Clinical and functional outcomes of cannabis use among individuals with anxiety disorders: A 3‐year population‐based longitudinal study
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BACKGROUND: Cannabis use has been reported to negatively affect the course and outcome of various psychiatric disorders, yet little is known on its effect on rates of remission from anxiety disorders and associated clinical and functional outcomes. METHODS: In this study, data were drawn from Waves 1 and 2 of the National Epidemiologic survey on Alcohol and Related Conditions, focusing on individuals who qualified for a diagnosis of any anxiety disorder (social anxiety, panic disorder, generalized anxiety disorder, and specific phobias) at Wave 1 (N = 3,723). Cannabis users and individuals with cannabis use disorders (CUDs) throughout a 4-year period were compared to nonusers in rates of remission, suicidality, general functioning, and quality of life at Wave 2, while controlling for baseline confounders. RESULTS: Although rates of remission decreased with level of cannabis use, this was not maintained in adjusted models. Aside from specific outcomes (individuals with CUDs were significantly more prone to report breaking up from a romantic relationship; adjusted odds ratio [AOR] = 3.85, 95% confidence interval [CI] = 1.66-8.97) and repeatedly quitting school (AOR = 6.02, 95% CI = 2.65-13.66)), following adjustment no additional differences were found in outcome measures. CONCLUSIONS: These findings add to previous reports suggesting that poorer outcome of anxiety disorders among cannabis users may be attributed mainly to differences in baseline factors and not cannabis use.
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Individuals with anxiety disorders who used cannabis but did not meet criteria for cannabis use disorder reported poorer quality of life than non-cannabis users in mental health and role functioning, while non-cannabis users did not differ from those with comorbid cannabis use disorder.
“finding that individuals with anxiety disorders who used cannabis (but did not meet criteria for cannabis use disorder) reported poorer QOL than non-cannabis users in the areas of mental health and role functioning, but non-cannabis users did not differ in QOL compared to those with comorbid cannabis use disorder [47].”
From Correlates of Quality of Life in Anxiety Disorders: Review of Recent Research (2021) · cites this paper as [47]
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Self-citation
- Authors
- Feingold, D., Rehm, J., Factor, H., Redler, A., & Lev‐Ran, S.
- Affiliations
- Lev Hasharon Hospital (IL)
- Centre for Addiction and Mental Health (CA)
- Ariel University (IL)
- Corresponding author
- Feingold, Daniel
- Venue
- Depression and Anxiety
- Publisher
- Wiley
- Published
- 2018-02-27
- Volume
- 35
- Issue
- 6
- Pages
- 490-501
- ISSN
- 1091-4269 (ISSN-L)
- 1520-6394
- OpenAlex
- W2792733662
- Cited by
- 24
- References
- 86
- Citations by year
- 2025: 3 · 2024: 3 · 2021: 5 · 2020: 7 · 2019: 6
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Depression and Anxiety (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- cannabis use, cannabis use disorder, anxiety disorders, remission, suicidality, quality of life, functional outcome, social anxiety, panic disorder, generalized anxiety disorder, specific phobia, romantic relationship dissolution, school dropout
- MeSH terms
- Marijuana Use, Adolescent, Adult, Aged, Anxiety Disorders, Female, Humans, Longitudinal Studies, Male, Middle Aged, Quality of Life, United States, Outcome Assessment, Health Care, Young Adult
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