Cited by 24Cannabis and Cannabinoid ResearchSubstance Abuse Treatment and OutcomesMental Health Treatment and Access

Clinical and functional outcomes of cannabis use among individuals with anxiety disorders: A 3‐year population‐based longitudinal study

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Feingold, Daniel, Rehm, Jürgen, Factor, Hagai, Redler, Avigayil, Lev‐Ran, Shaul·2018·Depression and Anxiety

Abstract

BACKGROUND: Cannabis use has been reported to negatively affect the course and outcome of various psychiatric disorders, yet little is known on its effect on rates of remission from anxiety disorders and associated clinical and functional outcomes. METHODS: In this study, data were drawn from Waves 1 and 2 of the National Epidemiologic survey on Alcohol and Related Conditions, focusing on individuals who qualified for a diagnosis of any anxiety disorder (social anxiety, panic disorder, generalized anxiety disorder, and specific phobias) at Wave 1 (N = 3,723). Cannabis users and individuals with cannabis use disorders (CUDs) throughout a 4-year period were compared to nonusers in rates of remission, suicidality, general functioning, and quality of life at Wave 2, while controlling for baseline confounders. RESULTS: Although rates of remission decreased with level of cannabis use, this was not maintained in adjusted models. Aside from specific outcomes (individuals with CUDs were significantly more prone to report breaking up from a romantic relationship; adjusted odds ratio [AOR] = 3.85, 95% confidence interval [CI] = 1.66-8.97) and repeatedly quitting school (AOR = 6.02, 95% CI = 2.65-13.66)), following adjustment no additional differences were found in outcome measures. CONCLUSIONS: These findings add to previous reports suggesting that poorer outcome of anxiety disorders among cannabis users may be attributed mainly to differences in baseline factors and not cannabis use.

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  • Individuals with anxiety disorders who used cannabis but did not meet criteria for cannabis use disorder reported poorer quality of life than non-cannabis users in mental health and role functioning, while non-cannabis users did not differ from those with comorbid cannabis use disorder.

    “finding that individuals with anxiety disorders who used cannabis (but did not meet criteria for cannabis use disorder) reported poorer QOL than non-cannabis users in the areas of mental health and role functioning, but non-cannabis users did not differ in QOL compared to those with comorbid cannabis use disorder [47].”

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Research works printed but not linked: 2

  1. Piccinelli, M., & Wilkinson, G. (2000). Gender differences in depression. British Journal of Psychiatry, 177, 486-492.
  2. Stetser, M., Shepherd, J., & Moore, T. F. (2002). Using the census 2000/2001 supplementary survey as a sampling frame for the national epidemi- ologic survey on alcohol and related conditions. Retrieved from https://www.amstat.org/sections/srms/proceedings/y2002/Files/JSM2 002-000531.pdf

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Authors
Feingold, D., Rehm, J., Factor, H., Redler, A., & Lev‐Ran, S.
Affiliations
  • Lev Hasharon Hospital (IL)
  • Centre for Addiction and Mental Health (CA)
  • Ariel University (IL)
Corresponding author
Feingold, Daniel
Venue
Depression and Anxiety
Publisher
Wiley
Published
2018-02-27
Volume
35
Issue
6
Pages
490-501
ISSN
  • 1091-4269 (ISSN-L)
  • 1520-6394
OpenAlex
W2792733662
Cited by
24
References
86
Citations by year
2025: 3 · 2024: 3 · 2021: 5 · 2020: 7 · 2019: 6
FWCI
2.88
Type
journal article
Language
en
Open access
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords
cannabis use, cannabis use disorder, anxiety disorders, remission, suicidality, quality of life, functional outcome, social anxiety, panic disorder, generalized anxiety disorder, specific phobia, romantic relationship dissolution, school dropout
MeSH terms
Marijuana Use, Adolescent, Adult, Aged, Anxiety Disorders, Female, Humans, Longitudinal Studies, Male, Middle Aged, Quality of Life, United States, Outcome Assessment, Health Care, Young Adult

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