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Cited by 320

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Motion correction and the use of motion covariates in multiple‐subject fMRI analysis

Open access
Johnstone, Tom, Ores Walsh, Kathleen S., Greischar, Larry L., Alexander, Andrew L., Fox, Andrew S., Davidson, Richard J., Oakes, Terrence R.·2006·Human Brain Mapping

Abstract

The impact of using motion estimates as covariates of no interest was examined in general linear modeling (GLM) of both block design and rapid event‐related functional magnetic resonance imaging (fMRI) data. The purpose of motion correction is to identify and eliminate artifacts caused by task‐correlated motion while maximizing sensitivity to true activations. To optimize this process, a combination of motion correction approaches was applied to data from 33 subjects performing both a block‐design and an event‐related fMRI experiment, including analysis: (1) without motion correction; (2) with motion correction alone; (3) with motion‐corrected data and motion covariates included in the GLM; and (4) with non–motion‐corrected data and motion covariates included in the GLM. Inclusion of covariates was found to be generally useful for increasing the sensitivity of GLM results in the analysis of event‐related data. When motion parameters were included in the GLM for event‐related data, it made little difference if motion correction was actually applied to the data. For the block design, inclusion of motion covariates had a deleterious impact on GLM sensitivity when even moderate correlation existed between motion and the experimental design. Based on these results, we present a general strategy for block designs, event‐related designs, and hybrid designs to identify and eliminate probable motion artifacts while maximizing sensitivity to true activations. Hum. Brain Mapp, 2006. © 2006 Wiley‐Liss, Inc.

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Crossref · 10.1002/hbm.20219

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Metadata

Authors
Johnstone, T., Ores Walsh, K. S., Greischar, L. L., Alexander, A. L., Fox, A. S., Davidson, R. J., & Oakes, T. R.
Venue
Human Brain Mapping
Publisher
Wiley
Published
2006-09-22
Volume
27
Issue
10
Pages
779-788
ISSN
  • 1065-9471 (ISSN-L)
  • 1097-0193
OpenAlex
W2103040438
Cited by
320
References
3
FWCI
8.82
Type
journal article
Language
en
Open access
green

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