Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 315,771 · see citing works

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518 · see citing works

Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions

Brunt, E. M., Janney, C. G., Di Bisceglie, A. M., Neuschwander-Tetri, B. A., & Bacon, B. R. (1999) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01377.x · Cited by 3,907 · see citing works

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity.

MATTEONI, C., YOUNOSSI, Z., GRAMLICH, T., BOPARAI, N., LIU, Y., & MCCULLOUGH, A. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70506-8 · Cited by 3,345 · see citing works

Mitochondrial diseases in man and mouse

Wallace, D. C. (1999) · Science · doi:10.1126/science.283.5407.1482 · Cited by 3,060 · see citing works

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?

Halliwell, B. B. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92211-x · Cited by 2,926 · see citing works

Nonalcoholic Steatohepatitis

Ludwig, J., Viggiano, T. R., McGill, D. B., & Ott, B. J. (1980) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(24)00530-5 · Cited by 2,903 · see citing works

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

Uysal, K. T., Wiesbrock, S. M., Marino, M. W., & Hotamisligil, G. S. (1997) · Nature · doi:10.1038/39335 · Cited by 2,234 · see citing works

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

Sanyal, A. J., Campbell–Sargent, C., Mirshahi, F., Rizzo, W. B., Contos, M. J., Sterling, R. K., Luketic, V. A., Shiffman, M. L., & Clore, J. N. (2001) · Gastroenterology · doi:10.1053/gast.2001.23256 · Cited by 2,078 · see citing works

Carnitine—metabolism and functions

Bremer, J. (1983) · Physiological Reviews · doi:10.1152/physrev.1983.63.4.1420 · Cited by 1,666 · see citing works

Classification of chronic viral hepatitis: a need for reassessment

Scheuer, P. J. (1991) · Journal of Hepatology · doi:10.1016/0168-8278(91)90084-o · Cited by 1,588 · see citing works

The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase

Kern, P. A., Saghizadeh, M., Ong, J. M., Bosch, R. J., Deem, R., & Simsolo, R. B. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117899 · Cited by 1,305 · see citing works

Guidelines for Healthy Weight

Willett, W. C., Dietz, W. H., & Colditz, G. A. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908053410607 · Cited by 1,141 · see citing works

Cytokines in Alcoholic and Nonalcoholic Steatohepatitis

Tilg, H., & Diehl, A. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011163432007 · Cited by 935 · see citing works

Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

Li, Z., Yang, S., Lin, H., Huang, J., Watkins, P. A., Moser, A. B., Desimone, C., Song, X.-Y., & Diehl, A. M. (2003) · Hepatology · doi:10.1053/jhep.2003.50048 · Cited by 930 · see citing works

The homeostasis model in the San Antonio Heart Study.

Haffner, S. M., Miettinen, H., & Stern, M. P. (1997) · Diabetes Care · doi:10.2337/diacare.20.7.1087 · Cited by 788 · see citing works

Mitochondrial DNA Damage and Dysfunction Associated With Oxidative Stress in Failing Hearts After Myocardial Infarction

Ide, T., Tsutsui, H., Hayashidani, S., Kang, D., Suematsu, N., Nakamura, K., Utsumi, H., Hamasaki, N., & Takeshita, A. (2001) · Circulation Research · doi:10.1161/01.res.88.5.529 · Cited by 733 · see citing works

Gene expression of tumor necrosis factor α and TNF-receptors, p55 and p75, in nonalcoholic steatohepatitis patients

Crespo, J., Cayón, A., Fernández-Gil, P. L., Hernández‐Guerra, M., Mayorga, M., Domínguez‐Díez, A., Fernández-Escalante, J. C., & Pons‐Romero, F. (2001) · Hepatology · doi:10.1053/jhep.2001.29628 · Cited by 693 · see citing works

Hydroxyl radicals and DNA base damage

Cadet, J., Delatour, T., Douki, T., Gasparutto, D., Pouget, J., Ravanat, J., & Sauvaigo, S. (1999) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s0027-5107(99)00004-4 · Cited by 687 · see citing works

Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

Fromenty, B., & Pessayre, D. (1995) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(95)00012-6 · Cited by 665 · see citing works

Etiopathogenesis of Nonalcoholic Steatohepatitis

Chitturi, S., & Farrell, G. C. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-12927 · Cited by 664 · see citing works

Mitochondrial disorders

Zeviani, M., & Spinazzola, A. (2003) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-003-0026-9 · Cited by 533 · see citing works

Mitochondrial abnormalities in non-alcoholic steatohepatitis

Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., & Parker, W. D. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80033-6 · Cited by 495 · see citing works

Muscle Carnitine Palmityltransferase Deficiency and Myoglobinuria

DiMauro, S., & DiMauro, P. M. M. (1973) · Science · doi:10.1126/science.182.4115.929 · Cited by 479 · see citing works

Tumor Necrosis Factor (TNF)-α Inhibits Insulin Signaling through Stimulation of the p55 TNF Receptor and Activation of Sphingomyelinase

Peraldi, P., Hotamisligil, G. S., Buurman, W. A., White, M. F., & Spiegelman, B. M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.22.13018 · Cited by 412 · see citing works

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes

Berson, A., de Beco, V., Lettéron, P., Robin, M. A., Moreau, C., Elkahwaji, J. E., Verthier, N., Feldmann, G., Fromenty, B., & Pessayre, D. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70590-6 · Cited by 402 · see citing works

Oxidative DNA damage, antioxidants, and cancer

Collins, A. R. (1999) · BioEssays · doi:10.1002/(sici)1521-1878(199903)21:3 · Cited by 312 · see citing works

V. Mitochondrial dysfunction in steatohepatitis

Pessayre, D., Mansouri, A., & Fromenty, B. (2002) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00426.2001 · Cited by 292 · see citing works

Non‐alcoholic steatohepatitis: another disease of affluence

James, *., & Day, C. (1999) · The Lancet · doi:10.1016/s0140-6736(99)00163-4 · Cited by 271 · see citing works

Nonalcoholic fatty liver disease: An agenda for clinical research

Younossi, Z. M., Diehl, A. M., & Ong, J. P. (2002) · Hepatology · doi:10.1053/jhep.2002.32483 · Cited by 260 · see citing works

The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles

Paradies, G., Petrosillo, G., Pistolese, M., & Ruggiero, F. M. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01082-6 · Cited by 251 · see citing works

Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation

Fromenty, B., Berson, A., & Pessayre, D. (1997) · Journal of Hepatology · doi:10.1016/s0168-8278(97)82328-8 · Cited by 175 · see citing works

Inhibition of target cell mitochondrial electron transfer by tumor necrosis factor

Lancaster, J. R., Laster, S. M., & Gooding, L. R. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80454-5 · Cited by 148 · see citing works

Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: Possible role in microvesicular steatosis induced by this antibiotic

Fréneaux, E., Labbe, G., Lettéron, P., Dinh, T. L., Degott, C., Genève, J., Larrey, D. G., & Pessayre, D. (1988) · Hepatology · doi:10.1002/hep.1840080513 · Cited by 144 · see citing works

Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis

Higuchi, M., Proske, R. J., & Yeh, E. T. H. (1998) · Oncogene · doi:10.1038/sj.onc.1202485 · Cited by 117 · see citing works

l-Carnitine therapy in home parenteral nutrition patients with abnormal liver tests and low plasma carnitine concentrations

Bowyer, B. A., Miles, J. M., Haymond, M. W., et al. (1988) · Gastroenterology · doi:10.1016/0016-5085(88)90433-7 · Cited by 107 · see citing works

Plasma carnitine insufficiency and effectiveness of L ‐carnitine therapy in patients with mitochondril myopathy

Campos, Y., Huertas, R., Lorenzo, G., et al. (1993) · Muscle & Nerve · doi:10.1002/mus.880160205 · Cited by 103 · see citing works

Inhibition by perhexiline of oxidative phosphorylation and the β-oxidation of fatty acids: Possible role in pseudoalcoholic liver lesions

Deschamps, D., DeBeco, V., Fisch, C., Fromenty, B., Guillouzo, A., & Pessayre, D. (1994) · Hepatology · doi:10.1002/hep.1840190422 · Cited by 103 · see citing works

Inhibition by perhexiline of oxidative phosphorylation and the beta-oxidation of fatty acids: possible role in pseudoalcoholic liver lesions.

Deschamps, D., DeBeco, V., Fisch, C., Fromenty, B., Guillouzo, A., & Pessayre, D. (1994) · PubMed · Cited by 100 · see citing works

Propionylcarnitine excretion in propionic and methylmalonic acidurias: a cause of carnitine deficiency

Donato, S. D., Rimoldi, M., Garavaglia, B., et al. (1984) · Clinica Chimica Acta · doi:10.1016/0009-8981(84)90187-6 · Cited by 90 · see citing works

Mitochondrial Disorders

Zeviani, M., Tiranti, V., & Piantadosi, C. (1998) · Medicine · doi:10.1097/00005792-199801000-00006 · Cited by 87 · see citing works

Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochrome b of the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells

Sánchez-Alcázar, J. A., Schneider, E., Martı́nez, M. A., Carmona, P., Hernández‐Muñoz, I., Siles, E., de la Torre, P., Ruı́z-Cabello, J., García‐Ruíz, I., & Solis-Herruzo, J. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.18.13353 · Cited by 85 · see citing works

Mitochondrial respiratory chain disorders and the liver

Morris, A. A. M. (1999) · Liver International · doi:10.1111/j.1478-3231.1999.tb00063.x · Cited by 71 · see citing works

Relation between central canals and portal tracts in alcoholic hepatitis

Gerber, M. A., & Pópper, H. (1972) · Human Pathology · doi:10.1016/s0046-8177(72)80073-x · Cited by 61 · see citing works

Thyroid hormone regulates oxidative phosphorylation in the cerebral cortex and striatum of neonatal rats

Martinez, B. V., del Hoyo, P., Martín, M. A., et al. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00487.x · Cited by 54 · see citing works

Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity.

Krähenbühl, S., Mang, G., Kupferschmidt, H. H. T., et al. (1995) · Gut · doi:10.1136/gut.37.1.140 · Cited by 52 · see citing works

Two novel gene mutations (Glu174→Lys, Phe383→Tyr) causing the "hepatic" form of carnitine palmitoyltransferase II deficiency

Yamamoto, S., Abe, H., Kohgo, T., Ogawa, A., Ohtake, A., Hayashibe, H., Sakuraba, H., Suzuki, Y., Aramaki, S., Takayanagi, M., et al. (1996) · Human Genetics · doi:10.1007/s004390050170 · Cited by 38 · see citing works

Free and total carnitine and acylcarnitine content of plasma, urine, liver and muscle of alcoholics

Sousa, C. D., Leung, N. W. Y., CHALMERS, R. A., et al. (1988) · Clinical Science · doi:10.1042/cs0750437 · Cited by 22 · see citing works

Increased liver carnitine content in obese women

Harper, P., Wadström, C., Bäckman, L., & Cederblad, G. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.1.18 · Cited by 19 · see citing works

Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications

Fabbrini, E., Sullivan, S., & Klein, S. (2010) · Hepatology · doi:10.1002/hep.23280 · Cited by 2,100 · see citing works

Role of Mitochondrial Dysfunction in Insulin Resistance

Kim, J.-A., Wei, Y., & Sowers, J. R. (2008) · Circulation Research · doi:10.1161/circresaha.107.165472 · Cited by 1,103 · see citing works

Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis

Koliaki, C., Szendroedi, J., Kaul, K., Jelenik, T., Nowotny, P., Jankowiak, F., Herder, C., Carstensen, M., Krausch, M., Knoefel, W. T., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.04.004 · Cited by 1,032 · see citing works

NAFLD and diabetes mellitus

Tilg, H., Moschen, A. R., & Roden, M. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.147 · Cited by 1,002 · see citing works

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, J. A., Coppotelli, G., Rolo, A. P., Palmeira, C. M., Ross, J. M., & Sinclair, D. A. (2022) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00626-7 · Cited by 990 · see citing works

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

Rolo, A. P., Teodoro, J. S., & Palmeira, C. M. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.003 · Cited by 955 · see citing works

Mitochondrial dysfunction in Nash: causes, consequences and possible means to prevent it

Begriche, K., Igoudjil, A., Pessayre, D., & Fromenty, B. (2006) · Mitochondrion · doi:10.1016/j.mito.2005.10.004 · Cited by 753 · see citing works

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

Sunny, N. E., Parks, E. J., Browning, J. D., & Burgess, S. C. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.11.004 · Cited by 672 · see citing works

The role of mitochondria in the pathogenesis of type 2 diabetes

Patti, M.-E., & Corvera, S. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0027 · Cited by 551 · see citing works

NASH: a mitochondrial disease

Pessayre, D., & Fromenty, B. (2005) · Journal of Hepatology · doi:10.1016/j.jhep.2005.03.004 · Cited by 441 · see citing works

Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases

Mantena, S. K., King, A. L., Andringa, K. K., Eccleston, H. B., & Bailey, S. M. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.029 · Cited by 429 · see citing works

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

Pirola, C. J., Gianotti, T. F., Burgueño, A. L., Rey-Funes, M., Loidl, C. F., Mallardi, P., Martino, J. S., Castaño, G. O., & Sookoian, S. (2013) · Gut · doi:10.1136/gutjnl-2012-302962 · Cited by 364 · see citing works

Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance

Matthews, V. B., Allen, T. L., Risis, S., Chan, M. H. S., Henstridge, D. C., Watson, N., Zaffino, L. A., Babb, J. R., Boon, J., Meikle, P. J., et al. (2010) · Diabetologia · doi:10.1007/s00125-010-1865-y · Cited by 334 · see citing works

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

Browning, J. D., Baker, J. A., Rogers, T., Davis, J., Satapati, S., & Burgess, S. C. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.007674 · Cited by 328 · see citing works

Hepatic lipid metabolism and non-alcoholic fatty liver disease

Tessari, P., Coracina, A., Cosma, A., & Tiengo, A. (2009) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2008.12.015 · Cited by 314 · see citing works

Hepatic Selective Insulin Resistance at the Intersection of Insulin Signaling and Metabolic Dysfunction-Associated Steatotic Liver Disease

Bo, T., Gao, L., Yao, Z., Shao, S., Wang, X., Proud, C. G., & Zhao, J. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.04.006 · Cited by 293 · see citing works

Central role of mitochondria in drug-induced liver injury

Pessayre, D., Fromenty, B., Berson, A., Robin, M.-A., Lettéron, P., Moreau, R., & Mansouri, A. (2012) · Drug Metabolism Reviews · doi:10.3109/03602532.2011.604086 · Cited by 277 · see citing works

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function<i>in vivo</i>

Mantena, S. K., Vaughn, D. P., Andringa, K. K., Eccleston, H. B., King, A. L., Abrams, G. A., Doeller, J. E., Kraus, D. W., Darley-Usmar, V. M., & Bailey, S. M. (2009) · Biochemical Journal · doi:10.1042/bj20080868 · Cited by 265 · see citing works

Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression

Peng, K.-Y., Watt, M. J., Rensen, S., Greve, J. W., Huynh, K., Jayawardana, K. S., Meikle, P. J., & Meex, R. C. R. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m085613 · Cited by 220 · see citing works

Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump

Aleo, M. D., Luo, Y., Swiss, R., Bonin, P. D., Potter, D. M., & Will, Y. (2014) · Hepatology · doi:10.1002/hep.27206 · Cited by 215 · see citing works

Abnormal Hepatic Energy Homeostasis in Type 2 Diabetes†

Szendroedi, J., Chmelik, M., Schmid, A. I., Nowotny, P., Brehm, A., Krssak, M., Moser, E., & Roden, M. (2009) · Hepatology · doi:10.1002/hep.23093 · Cited by 204 · see citing works

Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease

Gariani, K., Ryu, D., Menzies, K. J., Yi, H.-S., Stein, S., Zhang, H., Perino, A., Lemos, V., Katsyuba, E., Jha, P., et al. (2017) · Journal of Hepatology · doi:10.1016/j.jhep.2016.08.024 · Cited by 167 · see citing works

Thyroid hormone-related regulation of gene expression in human fatty liver.

Pihlajamäki, J., Boes, T., Kim, E.-Y., Dearie, F., Kim, B. W., Schroeder, J., Mun, E., Nasser, I., Park, P. J., Bianco, A. C., et al. (2009) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2009-0212 · Cited by 164 · see citing works

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver

Jelenik, T., Kaul, K., Séquaris, G., Flögel, U., Phielix, E., Kotzka, J., Knebel, B., Fahlbusch, P., Hörbelt, T., Lehr, S., et al. (2017) · Diabetes · doi:10.2337/db16-1147 · Cited by 154 · see citing works

Role of Innate Immune Response in Non-Alcoholic Fatty Liver Disease: Metabolic Complications and Therapeutic Tools

Meli, R., Mattace Raso, G., & Calignano, A. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00177 · Cited by 137 · see citing works

Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet

Serviddio, G., Giudetti, A. M., Bellanti, F., Priore, P., Rollo, T., Tamborra, R., Siculella, L., Vendemiale, G., Altomare, E., & Gnoni, G. V. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024084 · Cited by 128 · see citing works

Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice

Uddin, G. M., Youngson, N. A., Sinclair, D. A., & Morris, M. J. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00258 · Cited by 95 · see citing works

Effects of exercise training on intrahepatic lipid content in humans

Brouwers, B., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016) · Diabetologia · doi:10.1007/s00125-016-4037-x · Cited by 94 · see citing works

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis

Montfort, C. V., Matias, N., Fernandez, A., Fucho, R., de la Rosa, L. C., Martinez-Chantar, M. L., Mato, J. M., Machida, K., Tsukamoto, H., Murphy, M. P., et al. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.05.024 · Cited by 83 · see citing works

The Role of Lipid Accumulation in Liver and Muscle for Insulin Resistance and Type 2 Diabetes Mellitus in Humans

Krssak, M., & Roden, M. (2004) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/b:remd.0000021434.98627.dc · Cited by 68 · see citing works

Mitochondrial Reactive Oxygen Species Signal Hepatocyte Steatosis by Regulating the Phosphatidylinositol 3-Kinase Cell Survival Pathway

Kohli, R., Pan, X., Malladi, P., Wainwright, M. S., & Whitington, P. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701759200 · Cited by 67 · see citing works

Advancements in MAFLD Modeling with Human Cell and Organoid Models

Wang, S.-X., Yan, J.-S., & Chan, Y.-S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911850 · Cited by 22 · see citing works

Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

Amorim, R., Simões, I., Veloso, C., Carvalho, A., Simões, R., Pereira, F., Thiel, T., Normann, A., Morais, C., Jurado, A., et al. (2021) · Nutrients · doi:10.3390/nu13051723 · Cited by 21 · see citing works

Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells

Dhami-Shah, H., Vaidya, R., Talwadekar, M., Shaw, E., Udipi, S., Kolthur-Seetharam, U., & Vaidya, A. D. B. (2021) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2021.04.007 · Cited by 15 · see citing works

Aldafermin quantitatively improves inflammation in a 24-week clinical trial in patients with nonalcoholic steatohepatitis

Lan, T., Ruiz, L., Liu, W., et al. (2022) · Journal of Hepatology · doi:10.1016/s0168-8278(22)01222-3

Correction of endotoxemia in patients with nonalcoholic steatohepatitis

Собирова, Г. Н., Каримов, М. М., & Alavi, A. (2011) · Medical and Health Science Journal · doi:10.15208/mhsj.2011.180 · Cited by 2 · see citing works

Dataset for: A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for non-alcoholic steatohepatitis

Ejima, C., Kuroda, H., & Ishizaki, S. (2016) · Figshare · doi:10.6084/m9.figshare.3984502

Mixed steatohepatitis: more questions than answers (Part 1)

Raikhelson, K. L., Александровна, К. Э., & Владимировна, П. Е. (2020) · Terapevticheskii arkhiv · doi:10.26442/00403660.2020.12.200470 · Cited by 20 · see citing works

[Clinical and biochemical characteristics in patients with histology compatible with steatothepatitis in National Hospital Arzobispo Loayza, Lima, Peru, from 2010 to 2012].

Matos, A., Cabello, K. S. T., Miranda, A. L., et al. (2017) · PubMed