Hepatic lipid metabolism and non-alcoholic fatty liver disease

Design and validation of a histological scoring system for nonalcoholic fatty liver disease†

Kleiner, D. E., Brunt, E. M., Van Natta, M., Behling, C., Contos, M. J., Cummings, O. W., Ferrell, L. D., Liu, Y., Torbenson, M. S., Unalp‐Arida, A., et al. (2005) · Hepatology · doi:10.1002/hep.20701 · Cited by 10,791 · see citing works

Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci13505 · Cited by 5,652 · see citing works

Nonalcoholic Fatty Liver Disease

Angulo, P. (2002) · New England Journal of Medicine · doi:10.1056/nejmra011775 · Cited by 5,228 · see citing works

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

Yamauchi, T., Kamon, J., Minokoshi, Y., Ito, Y., Waki, H., Uchida, S., Yamashita, S., Noda, M., Kita, S., Ueki, K., et al. (2002) · Nature Medicine · doi:10.1038/nm788 · Cited by 4,238 · see citing works

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

Sanyal, A. J., Campbell–Sargent, C., Mirshahi, F., Rizzo, W. B., Contos, M. J., Sterling, R. K., Luketic, V. A., Shiffman, M. L., & Clore, J. N. (2001) · Gastroenterology · doi:10.1053/gast.2001.23256 · Cited by 2,078 · see citing works

Molecular mediators of hepatic steatosis and liver injury

Browning, J. D., & Horton, J. D. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200422422 · Cited by 1,772 · see citing works

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

Kersten, S., Seydoux, J., Peters, J. M., Gonzalez, F. J., Desvergne, B., & Wahli, W. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6223 · Cited by 1,649 · see citing works

Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population

Szczepaniak, L. S., Nurenberg, P., Leonard, D. S., Browning, J. D., Reingold, J. S., Grundy, S. M., Hobbs, H. H., & Dobbins, R. L. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00064.2004 · Cited by 1,562 · see citing works

Nonalcoholic Fatty Liver Disease: Predictors of Nonalcoholic Steatohepatitis and Liver Fibrosis in the Severely Obese

Dixon, J. B., Bhathal, P. S., & O’Brien, P. E. (2001) · Gastroenterology · doi:10.1053/gast.2001.25540 · Cited by 1,365 · see citing works

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

Xu, A., Wang, Y., Keshaw, H., Xu, L. Y., Lam, K. S. L., & Cooper, G. J. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17797 · Cited by 1,298 · see citing works

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

Xu, A., Wang, Y., Keshaw, H., Xu, L. Y., Lam, K. S. L., & Cooper, G. J. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200317797 · Cited by 1,298 · see citing works

5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

Corton, J. M., Gillespie, J. G., Hawley, S. A., & Hardie, D. G. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.tb20498.x · Cited by 1,232 · see citing works

Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis

Rajala, M. W., & Scherer, P. E. (2003) · Endocrinology · doi:10.1210/en.2003-0580 · Cited by 1,190 · see citing works

The AMP-activated protein kinase pathway – new players upstream and downstream

Hardie, D. G. (2004) · Journal of Cell Science · doi:10.1242/jcs.01540 · Cited by 1,136 · see citing works

Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J.-M., Lee, C. H., Oh, W. K., Kim, C. T., et al. (2006) · Diabetes · doi:10.2337/db06-0006 · Cited by 1,054 · see citing works

Resistin, an Adipokine with Potent Proinflammatory Properties

Bokarewa, M. I., Nagaev, I., Dahlberg, L., Smith, U., & Tarkowski, A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.9.5789 · Cited by 1,037 · see citing works

The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways

Fryer, L. G. D., Patel, A. P., & Carling, D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202489200 · Cited by 1,030 · see citing works

Beyond insulin resistance in NASH: TNF-α or adiponectin?

Hui, J. M., Hodge, A., Farrell, G. C., Kench, J. G., Kriketos, A., & George, J. (2004) · Hepatology · doi:10.1002/hep.20280 · Cited by 942 · see citing works

Lipid Metabolism and Liver Inflammation. II. Fatty liver disease and fatty acid oxidation

Reddy, J. K., & Rao, M. S. (2006) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00521.2005 · Cited by 860 · see citing works

Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

Winder, W. W., & Hardie, D. G. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.2.e299 · Cited by 799 · see citing works

Dietary Habits and Their Relations to Insulin Resistance and Postprandial Lipemia in Nonalcoholic Steatohepatitis

Musso, G., Gambino, R., Michieli, F. D., Cassader, M., Rizzetto, M., Durazzo, M., Fagà, E., Silli, B., & Pagano, G. (2003) · Hepatology · doi:10.1053/jhep.2003.50132 · Cited by 758 · see citing works

Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

Wei, Y., Wang, D., Topczewski, F., & Pagliassotti, M. J. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00644.2005 · Cited by 736 · see citing works

Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis.

Pérez-Carreras, M., Del Hoyo, P., Martín, M. A., Rubio, J. C., Martín, A., Castellano, G., Colina, F., Arenas, J., & Solis-Herruzo, J. A. (2003) · Hepatology · doi:10.1002/hep.1840380426 · Cited by 734 · see citing works

Increased Levels of Nuclear SREBP-1c Associated with Fatty Livers in Two Mouse Models of Diabetes Mellitus

Shimomura, I., Bashmakov, Y. K., & Horton, J. D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.30028 · Cited by 708 · see citing works

Overproduction of large VLDL particles is driven by increased liver fat content in man

Adiels, M., Taskinen, M.-R., Packard, C., Caslake, M. J., Soro-Paavonen, A., Westerbacka, J., Vehkavaara, S., Häkkinen, A., Olofsson, S.-O., Yki-Järvinen, H., et al. (2006) · Diabetologia · doi:10.1007/s00125-005-0125-z · Cited by 690 · see citing works

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

Yamashita, H., Takenoshita, M., Sakurai, M., Bruick, R. K., Henzel, W. J., Shillinglaw, W., Arnot, D., & Uyeda, K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.161284298 · Cited by 682 · see citing works

Metformin reverses fatty liver disease in obese, leptin-deficient mice.

Lin, H. Z., Yang, S. Q., Chuckaree, C., Kuhajda, F., Ronnet, G., & Diehl, A. M. (2000) · Nature Medicine · doi:10.1038/79697 · Cited by 673 · see citing works

Etiopathogenesis of Nonalcoholic Steatohepatitis

Chitturi, S., & Farrell, G. C. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-12927 · Cited by 664 · see citing works

Functional specialization of different hepatocyte populations

Jungermann, K. A., & Katz, N. R. (1989) · Physiological Reviews · doi:10.1152/physrev.1989.69.3.708 · Cited by 655 · see citing works

Malonyl-CoA, fuel sensing, and insulin resistance

Ruderman, N. B., Saha, A. K., Vavvas, D. G., & Witters, L. A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.276.1.e1 · Cited by 644 · see citing works

Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects

Gastaldelli, A., Cusi, K., Pettiti, M., Hardies, J., Miyazaki, Y., Berria, R., Buzzigoli, E., Sironi, A. M., Cersosimo, E., Ferrannini, E., et al. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.04.068 · Cited by 629 · see citing works

DIETARY n-6 AND n-3 FATTY ACID BALANCE AND CARDIOVASCULAR HEALTH

Wijendran, V., & Hayes, K. C. (2004) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.24.012003.132106 · Cited by 607 · see citing works

Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): A population based study

Zelber‐Sagi, S., Nitzan, D., Goldsmith, R., Webb, M., Blendis, L. M., Halpern, Z., & Oren, R. (2007) · Journal of Hepatology · doi:10.1016/j.jhep.2007.06.020 · Cited by 545 · see citing works

Regulation of Plasma Triglycerides in Insulin Resistance and Diabetes

Ginsberg, H. N., Zhang, Y.-L., & Hernandez-Ono, A. (2005) · Archives of Medical Research · doi:10.1016/j.arcmed.2005.01.005 · Cited by 531 · see citing works

Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

Viollet, B., Foretz, M., Guigas, B., Horman, S., Dentin, R., Bertrand, L., Hue, L., & Andréelli, F. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.108506 · Cited by 529 · see citing works

In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases

Seki, S., Kitada, T., Yamada, T., Sakaguchi, H., Nakatani, K., & Wakasa, K. (2002) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00073-9 · Cited by 523 · see citing works

Adipocytokines and Insulin Resistance

Pittas, A. G., Joseph, N. A., & Greenberg, A. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031005 · Cited by 515 · see citing works

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

Foufelle, F., & Ferré, P. (2002) · Biochemical Journal · doi:10.1042/bj20020430 · Cited by 479 · see citing works

The role of AMP-activated protein kinase in the action of ethanol in the liver

You, M., Matsumoto, M., Pacold, C. M., Cho, W. K., & Crabb, D. W. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.09.049 · Cited by 469 · see citing works

Animal Models of Steatosis

Koteish, A. A., & Diehl, A. M. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-12932 · Cited by 447 · see citing works

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro

Galli, A., Crabb, D. W., Ceni, E., Salzano, R., Mello, T., Svegliati–Baroni, G., Ridolfi, F., Trozzi, L., Surrenti, C., & Casini, A. (2002) · Gastroenterology · doi:10.1053/gast.2002.33666 · Cited by 440 · see citing works

Obesity Induces Expression of Uncoupling Protein-2 in Hepatocytes and Promotes Liver ATP Depletion

Chavin, K. D., Yang, S., Lin, H. Z., Chatham, J. C., Chacko, V. P., Hoek, J. B., Walajtys-Rode, E., Rashid, A., Chen, C., Huang, C., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5692 · Cited by 440 · see citing works

Diseases of liporegulation: new perspective on obesity and related disorders

Unger, R. H., & Orci, L. (2001) · The FASEB Journal · doi:10.1096/fj.00-0590 · Cited by 429 · see citing works

Gene expression in human NAFLD

Greco, D., Kotronen, A., Westerbacka, J., Puig, O., Arkkila, P., Kiviluoto, T., Laitinen, S., Kolak, M., Fisher, R. M., Hamsten, A., et al. (2008) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00074.2008 · Cited by 427 · see citing works

Nonalcoholic fatty liver disease and the metabolic syndrome

Marchesini, G., Marzocchi, R., Agostini, F., & Bugianesi, E. (2005) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000174153.53683.f2 · Cited by 420 · see citing works

Acquired Obesity Is Associated with Changes in the Serum Lipidomic Profile Independent of Genetic Effects – A Monozygotic Twin Study

Pietiläinen, K. H., Sysi‐Aho, M., Rissanen, A., Seppänen‐Laakso, T., Yki‐Järvinen, H., Kaprio, J. A., & Orešič, M. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000218 · Cited by 415 · see citing works

Adiponectin and its receptors in non-alcoholic steatohepatitis

Kaser, S., Moschen, A. R., Cayon, A., Kaser, A., Crespo, J., Pons-Romero, F., Ebenbichler, C. F., Patsch, J. R., & Tilg, H. (2004) · Gut · doi:10.1136/gut.2003.037010 · Cited by 412 · see citing works

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes

Berson, A., de Beco, V., Lettéron, P., Robin, M. A., Moreau, C., Elkahwaji, J. E., Verthier, N., Feldmann, G., Fromenty, B., & Pessayre, D. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70590-6 · Cited by 402 · see citing works

Nonalcoholic Fatty Liver Disease: Cytokine-Adipokine Interplay and Regulation of Insulin Resistance

Tilg, H., & Hotamışlıgil, G. S. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.05.054 · Cited by 385 · see citing works

Role of resistin in diet-induced hepatic insulin resistance

Muse, E. D., Obici, S., Bhanot, S., Monia, B. P., McKay, R. A., Rajala, M. W., Scherer, P. E., & Rossetti, L. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21270 · Cited by 371 · see citing works

Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance

James, O., & Day, C. P. (1998) · Journal of Hepatology · doi:10.1016/s0168-8278(98)80073-1 · Cited by 370 · see citing works

Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?

Chitturi, S., Farrell, G. C., Frost, L., Kriketos, A. D., Lin, R., Liddle, C., Samarasinghe, D., & George, J. (2002) · Hepatology · doi:10.1053/jhep.2002.34738 · Cited by 363 · see citing works

Regulation of Hepatic De Novo Lipogenesis in Humans

Hellerstein, M. K., Schwarz, J.-M., & Neese, R. A. (1996) · Annual Review of Nutrition · doi:10.1146/annurev.nu.16.070196.002515 · Cited by 349 · see citing works

Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase

Fan, C.-Y., Pan, J., Usuda, N., Yeldandi, A. V., Rao, M. S., & Reddy, J. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.25.15639 · Cited by 343 · see citing works

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes.

García‐Ruiz, C., Colell, A., Morales, A., Kaplowitz, N., & Fernández-Checa, J. C. (1995) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10539-7 · Cited by 337 · see citing works

Apolipoprotein synthesis in nonalcoholic steatohepatitis

Charlton, M., Raghavakaimal, S., Rasmussen, D. L., Lindor, K. D., & Nair, S. K. (2002) · Hepatology · doi:10.1053/jhep.2002.32527 · Cited by 332 · see citing works

Adipose Tissue Inflammation and Increased Ceramide Content Characterize Subjects With High Liver Fat Content Independent of Obesity

Kolak, M., Westerbacka, J., Velagapudi, V., Wågsäter, D., Yetukuri, L., Makkonen, J., Rissanen, A., Häkkinen, A., Lindell, M., Bergholm, R., et al. (2007) · Diabetes · doi:10.2337/db07-0111 · Cited by 318 · see citing works

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

Dentin, R. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25256 · Cited by 315 · see citing works

Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition

Cave, M. C., Deaciuc, I. V., Mendez, C. M., Song, Z., Joshi‐Barve, S., Barve, S. S., & McClain, C. J. (2007) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2006.12.006 · Cited by 290 · see citing works

NUTRITIONAL AND HORMONAL REGULATION OF ENZYMES IN FAT SYNTHESIS: Studies of Fatty Acid Synthase and Mitochondrial Glycerol-3-Phosphate Acyltransferase Gene Transcription

Sul, H. S., & Wang, D. (1998) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.18.1.331 · Cited by 280 · see citing works

Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

Pan, M., Cederbaum, A. I., Zhang, Y., Ginsberg, H. N., Williams, K. J., & Fisher, E. A. A. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19197 · Cited by 278 · see citing works

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK

Watt, M. J., Dzamko, N. L., Thomas, W. G., Rose‐John, S., Ernst, M., Carling, D., Kemp, B. E., Febbraio, M. A., & Steinberg, G. R. (2006) · Nature Medicine · doi:10.1038/nm1383 · Cited by 275 · see citing works

Adipokines in NASH: Postprandial Lipid Metabolism as a Link Between Adiponectin and Liver Disease *

Musso, G., Gambino, R., Durazzo, M., Biroli, G., Carello, M., Fagà, E., Pacini, G., Michieli, F. D., Rabbione, L., Premoli, A., et al. (2005) · Hepatology · doi:10.1002/hep.20896 · Cited by 271 · see citing works

Fat in the liver and insulin resistance

Yki‐Järvinen, H. (2005) · Annals of Medicine · doi:10.1080/07853890510037383 · Cited by 267 · see citing works

Plasma adiponectin is decreased in nonalcoholic fatty liver disease

Pagano, C., Soardo, G., Esposito, W., Fallo, F., Basan, L., Donnini, D., Federspil, G., Sechi, L. A., & Vettor, R. (2005) · European Journal of Endocrinology · doi:10.1530/eje.1.01821 · Cited by 257 · see citing works

Synthesis and function of hepatic very-low-density lipoprotein

Gibbons, G. F., Wiggins, D. K., Brown, A.-M., & Hebbachi, A.-M. (2004) · Biochemical Society Transactions · doi:10.1042/bst0320059 · Cited by 254 · see citing works

Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle.

Barazzoni, R., Bosutti, A., Stebel, M., Cattin, M. R., Roder, E., Visintin, L., Cattin, L., Biolo, G., Zanetti, M., & Guarnieri, G. (2005) · American Journal of Physiology. Endocrinology and Metabolism · doi:10.1152/ajpendo.00115.2004 · Cited by 250 · see citing works

How different is the dietary pattern in non-alcoholic steatohepatitis patients?

Cortez‐Pinto, H., Jesus, L., Barros, H., Lopes, C. M. M., de Moura, M. C., & Camilo, M. (2006) · Clinical Nutrition · doi:10.1016/j.clnu.2006.01.027 · Cited by 245 · see citing works

Mechanisms of Disease: adipocytokines and visceral adipose tissue—emerging role in nonalcoholic fatty liver disease

Schäffler, A., Schölmerich, J., & Büchler, C. (2005) · Nature Clinical Practice Gastroenterology &#38 Hepatology · doi:10.1038/ncpgasthep0186 · Cited by 240 · see citing works

Relationships between Desacylated and Acylated Ghrelin and Insulin Sensitivity in the Metabolic Syndrome

Barazzoni, R., Zanetti, M., Ferreira, C., Vinci, P., Pirulli, A., Mucci, M., Dore, F., Fonda, M., Ciocchi, B., Cattin, L., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2527 · Cited by 238 · see citing works

Behavior therapy for nonalcoholic fatty liver disease: The need for a multidisciplinary approach

Bellentani, S., Grave, R. D., Suppini, A., & Marchesini, G. (2007) · Hepatology · doi:10.1002/hep.22009 · Cited by 236 · see citing works

Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase

Hutber, C. A., Hardie, D. G., & Winder, W. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.2.e262 · Cited by 229 · see citing works

Obesity and Nonalcoholic Fatty Liver Disease

Angulo, P. (2008) · Nutrition Reviews · doi:10.1111/j.1753-4887.2007.tb00329.x · Cited by 223 · see citing works

Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo

Saha, A. K., Avilucea, P. R., Ye, J.-M., Assifi, M. M., Kraegen, E. W., & Ruderman, N. B. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.12.120 · Cited by 218 · see citing works

Dietary Composition and Nonalcoholic Fatty Liver Disease

Solga, S. F., Alkhuraishe, A. R., Clark, J. M., TORBENSON, M., Greenwald, A., Diehl, A. M., & Magnuson, T. H. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000043367.69470.b7 · Cited by 214 · see citing works

Obesity and Nonalcoholic Fatty Liver Disease

Angulo, P. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.jun.s57-s63 · Cited by 198 · see citing works

Increased Serum Resistin in Nonalcoholic Fatty Liver Disease Is Related to Liver Disease Severity and Not to Insulin Resistance

Pagano, C., Soardo, G., Pilon, C., Milocco, C., Basan, L., Milan, G., Donnini, D., Faggian, D., Mussap, M., Plebani, M., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1056 · Cited by 190 · see citing works

Hepatic Gene Expression in Histologically Progressive Nonalcoholic Steatohepatitis

Raghavakaimal, S., Rosado, B., Rasmussen, D. L., & Charlton, M. (2003) · Hepatology · doi:10.1053/jhep.2003.50290 · Cited by 184 · see citing works

The Evolving Role of Leptin and Adiponectin in Chronic Liver Diseases

Tsochatzis, E. A., Papatheodoridis, G., & Archimandritis, A. J. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00848.x · Cited by 182 · see citing works

Metabolic Syndrome Is Associated with Greater Histologic Severity, Higher Carbohydrate, and Lower Fat Diet in Patients with NAFLD

Kang, H., Greenson, J. K., Omo, J. T., Chao, C., Peterman, D., Anderson, L., Foess-Wood, L., Sherbondy, M. A. H., & Conjeevaram, H. S. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00719.x · Cited by 180 · see citing works

Bax inhibition protects against free fatty acid-induced lysosomal permeabilization

Feldstein, A. E., Werneburg, N. W., Li, Z., Bronk, S. F., & Gores, G. J. (2006) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00509.2005 · Cited by 174 · see citing works

Associations between plasma adiponectin concentrations and liver histology in patients with nonalcoholic fatty liver disease

Targher, G., Bertolini, L., Rodella, S., Zoppini, G., Scala, L., Zenari, L., & Falezza, G. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02527.x · Cited by 172 · see citing works

Statins and hepatic steatosis: Perspectives from the Dallas Heart Study

Browning, J. D. (2006) · Hepatology · doi:10.1002/hep.21248 · Cited by 161 · see citing works

Ghrelin, the peripheral hunger hormone

Higgins, S. C., Gueorguiev, M., & Korbonits, M. (2007) · Annals of Medicine · doi:10.1080/07853890601149179 · Cited by 158 · see citing works

Usefulness of a Combined Evaluation of the Serum Adiponectin Level, HOMA-IR, and Serum Type IV Collagen 7S Level to Predict the Early Stage of Nonalcoholic Steatohepatitis

Shimada, M., Kawahara, H., Ozaki, K., Fukura, M., Yano, H., Tsuchishima, M., Tsutsumi, M., & Takase, S. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01322.x · Cited by 156 · see citing works

Clinical usefulness of biochemical markers of liver fibrosis in patients with nonalcoholic fatty liver disease

Sakugawa, H. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i2.255 · Cited by 156 · see citing works

AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats

Assifi, M. M., Suchánková, G., Constant, S., Prentki, M., Saha, A. K., & Ruderman, N. B. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00144.2005 · Cited by 155 · see citing works

Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle

Collier, C., Bruce, C. R., Smith, A. C., Lopaschuk, G. D., & Dyck, D. J. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00272.2005 · Cited by 155 · see citing works

Regulation of fat metabolism in the liver: link to non-alcoholic hepatic steatosis and impact of physical exercise

Lavoie, J.-M., & Gauthier, M. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6600-y · Cited by 149 · see citing works

Oxidative stress, KLF6 and transforming growth factor-β up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats

Stärkel, P., Sempoux, C. L., Leclercq, I. A., Hérin, M., Deby, C. M. T., Desager, J., & Horsmans, Y. (2003) · Journal of Hepatology · doi:10.1016/s0168-8278(03)00360-x · Cited by 132 · see citing works

Influence of Plasma Free Fatty Acids on Lipoprotein Synthesis and Diabetic Dyslipidemia

Julius, U. (2003) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-2003-41284 · Cited by 131 · see citing works

Hepatic preconditioning preserves energy metabolism during sustained ischemia

Peralta, C., Bartrons, R., Riera, L., Manzano, À., Xaus, C., Gelpı́, E., & Roselló‐Catafau, J. (2000) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2000.279.1.g163 · Cited by 131 · see citing works

Diabetes and liver disease: An ominous association

Moscatiello, S., Manini, R., & Marchesini, G. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2006.08.004 · Cited by 129 · see citing works

Diabetes mellitus, obesity, and hepatic steatosis.

Youssef, W. I., & McCullough, A. J. (2002) · PubMed · Cited by 127 · see citing works

Inhibitors of hepatic microsomal triacylglycerol hydrolase decrease very low density lipoprotein secretion

Gilham, D., Ho, S. B., Rasouli, M., Martres, P., Vance, D. E., & Lehner, R. S. (2003) · The FASEB Journal · doi:10.1096/fj.02-0728fje · Cited by 115 · see citing works

Levels of serum hyaluronic acid, TNF-alpha and IL-8 in patients with nonalcoholic steatohepatitis.

Bahçecioğlu, İ. H., Yalnız, M., Ataseven, H., İlhan, A., Özercan, İ. H., Seçkin, D., & Şahin, K. (2005) · PubMed · Cited by 111 · see citing works

Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis

Yamaguchi, K., Yang, L., McCall, S. J., Huang, J., Yu, X. X., Pandey, S., Bhanot, S., Monia, B. P., Li, Y.-X., & Diehl, A. M. (2007) · Hepatology · doi:10.1002/hep.21988 · Cited by 102 · see citing works

AICAR, an AMPK Activator, Has Protective Effects on Alcohol‐Induced Fatty Liver in Rats

Tomita, K., Tamiya, G., Ando, S., Kitamura, N., Koizumi, H., Kato, S., Horie, Y., Kaneko, T., Azuma, T., Nagata, H., et al. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000191126.11479.69 · Cited by 102 · see citing works

Hepatic VLDL Production in ob/ob Mice Is Not Stimulated by Massive De Novo Lipogenesis but Is Less Sensitive to the Suppressive Effects of Insulin

Wiegman, C., Bandsma, R., Ouwens, D. M., van der Sluijs, F. H., Havinga, R., Boer, T. S., Reijngoud, D., Romijn, J. A., & Kuipers, F. (2003) · Diabetes · doi:10.2337/diabetes.52.5.1081 · Cited by 99 · see citing works

Non‐invasive markers to predict the liver fibrosis in non‐alcoholic fatty liver disease

Lydatakis, H., Hager, I. P., Kostadelou, E., Mpousmpoulas, S., Pappas, S. I., & Diamantis, I. D. (2006) · Liver International · doi:10.1111/j.1478-3231.2006.01312.x · Cited by 97 · see citing works

Functional foods for coronary heart disease risk reduction: a meta-analysis using a multivariate approach

de Castro, I. A., Barroso, L. P., & Sinnecker, P. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.1.32 · Cited by 95 · see citing works

Effect of dietary protein intake on insulin secretion and glucose metabolism in insulin-dependent diabetes mellitus

Linn, T., Geyer, R., Prassek, S., & Laube, H. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.11.8923841 · Cited by 95 · see citing works

Leptin, free leptin index, insulin resistance and liver fibrosis in children with non-alcoholic fatty liver disease

Nobili, V., Manco, M., Ciampalini, P., Ciommo, V. M. D., Vito, R. D., Piemonte, F., Comparcola, D., Guidi, R., & Marcellini, M. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02288 · Cited by 94 · see citing works

Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins

Pietiläinen, K. H., Rissanen, A., Kaprio, J. A., Mäkimattila, S., Häkkinen, A., Westerbacka, J., Sutinen, J., Vehkavaara, S., & Yki‐Järvinen, H. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00381.2004 · Cited by 90 · see citing works

Postprandial triglyceride‐rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients

Cassader, M., Gambino, R., Musso, G., Depetris, N., Mecca, F., Cavallo‐Perin, P., Pacini, G., Rizzetto, M., & Pagano, G. (2001) · Lipids · doi:10.1007/s11745-001-0822-5 · Cited by 88 · see citing works

Effect of Reye's syndrome serum on isolated chinchilla liver mitochondria.

Tonsgard, J. H., & Getz, G. S. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112039 · Cited by 88 · see citing works

The role of leptin in progression of non-alcoholic fatty liver disease

Ikejima, K., Okumura, K., LANG, T., HONDA, H., Abe, W., Yamashina, S., ENOMOTO, N., TAKEI, Y., & Sato, N. (2005) · Hepatology Research · doi:10.1016/j.hepres.2005.09.024 · Cited by 85 · see citing works

Functional foods for coronary heart disease risk reduction: a meta-analysis using a multivariate approach

de Castro, I. A., Barroso, L. P., & Sinnecker, P. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.1.32 · Cited by 78 · see citing works

Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: An open question

Loria, P., Lonardo, A., Bellentani, S., Day, C., Marchesini, G., & Carulli, N. (2007) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2007.01.007 · Cited by 77 · see citing works

Purification and Characterization of Rat Skeletal Muscle Acetyl-CoA Carboxylase

Trumble, G. E., Smith, M. A., & Winder, W. W. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.0192f.x · Cited by 76 · see citing works

Ghrelin Enhances in Vivo Skeletal Muscle But Not Liver AKT Signaling in Rats

Barazzoni, R., Zanetti, M., Cattin, M. R., Visintin, L., Vinci, P., Cattin, L., Stebel, M., & Guarnieri, G. (2007) · Obesity · doi:10.1038/oby.2007.313 · Cited by 71 · see citing works

Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo

Fishman, S., Muzumdar, R. H., Atzmon, G., Ma, X., Yang, X., Einstein, F. H., & Barzilai, N. (2006) · The FASEB Journal · doi:10.1096/fj.06-6557com · Cited by 70 · see citing works

Contribution of de novo fatty acid synthesis to very low density lipoprotein triacylglycerols: evidence from mass isotopomer distribution analysis of fatty acids synthesized from [2H6]ethanol

Yang, L.-Y., Kuksis, A., Myher, J. J., & Steiner, G. A. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37614-8 · Cited by 68 · see citing works

Purification and Characterization of Rat Skeletal Muscle Acetyl-CoA Carboxylase

Trumble, G. E., Smith, M. A., & Winder, W. W. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.tb20686.x · Cited by 68 · see citing works

Methionine Deficiency and Hepatic Injury in a Dietary Steatohepatitis Model

Oz, H. S., Chen, T. S., & Neuman, M. G. (2007) · Digestive Diseases and Sciences · doi:10.1007/s10620-007-9900-7 · Cited by 64 · see citing works

Low Ghrelin Concentrations in Nonalcoholic Fatty Liver Disease Are Related to Insulin Resistance

Marchesini, G., Pagotto, U., Bugianesi, E., Iasio, R. D., Manini, R., Vanni, E., Pasquali, R., Melchionda, N., & Rizzetto, M. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031094 · Cited by 64 · see citing works

Leptin activates AMP-activated protein kinase in hepatic cells via a JAK2-dependent pathway

Uotani, S., Abe, T., & Yamaguchi, Y. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.10.015 · Cited by 52 · see citing works

Serum Adipokine and Ghrelin Levels in Nonalcoholic Steatohepatitis

Yalnız, M., Bahçecioğlu, İ. H., Ataseven, H., Üstündağ, B., İlhan, F., Poyrazoğlu, O. K., & Erensoy, A. (2006) · Mediators of Inflammation · doi:10.1155/mi/2006/34295 · Cited by 49 · see citing works

Flexibility of zonation of fatty acid oxidation in rat liver

Guzmán, M., Bijleveld, C., & Geelen, M. J. H. (1995) · Biochemical Journal · doi:10.1042/bj3110853 · Cited by 46 · see citing works

Serum Resistin and Hepatic Fat Content in Nondiabetic Individuals

Perseghin, G., Lattuada, G., COBELLI, F. D., Ntali, G., Esposito, A., Burska, A. N., Belloni, E., Canu, T., Ragogna, F., Scifo, P., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1368 · Cited by 44 · see citing works

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside causes acute hepatic insulin resistance in vivo.

Pencek, R., Shearer, J., Camacho, R. C., James, F. D., Lacy, D., Fueger, P., Donahue, E., Snead, W., & Wasserman, D. (2005) · Diabetes · doi:10.2337/diabetes.54.2.355 · Cited by 41 · see citing works

Effects of a Long-Term High-Fat Diet and Switching from a High-Fat to Low-Fat, Standard Diet on Hepatic Fat Accumulation in Sprague-Dawley Rats

Omagari, K., Kato, S., Tsuneyama, K., Inohara, C., Kuroda, Y., Tsukuda, H., Fukazawa, E., Shiraishi, K., & Mune, M. (2008) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0303-1 · Cited by 39 · see citing works

Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice

Nagao, K., Inoue, N., Ujino, Y., Kouki, H. I. G. A., Shirouchi, B., Wang, Y., & Yanagita, T. (2008) · Lipids in Health and Disease · doi:10.1186/1476-511x-7-8 · Cited by 26 · see citing works

[Role of oxidative stress in non-alcoholic steatohepatitis].

Mitsuyoshi, H., Itoh, Y., & Okanoue, T. (2006) · PubMed · Cited by 22 · see citing works

Metformin treatment of rats with diet-induced overweight and hypertriglyceridemia decreases plasma triglyceride concentrations, while decreasing triglyceride and increasing ketone body output by the isolated perfused liver

Tessari, P., & Tiengo, A. (2008) · Acta Diabetologica · doi:10.1007/s00592-008-0032-0 · Cited by 21 · see citing works

Hepatic zonation of the formation and hydrolysis of cholestery esters in periportal and perivenous parenchymal cells

Romero, J. R., Fresnedo, O., Isusi, E., Barrionuevo, J., & Ochoa, B. (1999) · Lipids · doi:10.1007/s11745-999-0439-8 · Cited by 11 · see citing works

Perfused Liver Carnitine Palmitoyl-Transferase Activity and Ketogenesis in Streptozotocin Treated and Genetic Hyperinsulinemic Rats. Effect of Glucagon

Nosadini, R., Ursini, F., Tessari, P., Giengo, A., & Gregolin, C. S. (1979) · Hormone and Metabolic Research · doi:10.1055/s-0028-1092794 · Cited by 9 · see citing works

Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase

Gilham, D., Perreault, K. R., Holmes, C. F. B., Brindley, D. N., Vance, D. E., & Lehner, R. S. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2005.08.013 · Cited by 8 · see citing works

Glycerophosphate acyltransferase activity in perfused liver of normal and hyperlipemic rats: Glucagon effect

Tessari, P., Meneghel, A., Avogaro, A., Duner, E., Prato, S. D., Tuzzato, M., & Tiengo, A. (1981) · Acta Diabetologica · doi:10.1007/bf02042820 · Cited by 4 · see citing works

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

Ipsen, D. H., Lykkesfeldt, J., & Tveden-Nyborg, P. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2860-6 · Cited by 1,471 · see citing works

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

Rolo, A. P., Teodoro, J. S., & Palmeira, C. M. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.003 · Cited by 955 · see citing works

Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline

Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887 · see citing works

De novo lipogenesis in health and disease

Ameer, F., Scandiuzzi, L., Hasnain, S., Kalbacher, H., & Zaidi, N. (2014) · Metabolism · doi:10.1016/j.metabol.2014.04.003 · Cited by 612 · see citing works

Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis

Spahis, S., DELVIN, E. E., Borys, J.-M., & Levy, E. H. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6776 · Cited by 386 · see citing works

Acetaldehyde adducts in alcoholic liver disease

Setshedi, M., Wands, J. R., & de la Monte, S. M. (2010) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.3.3.12288 · Cited by 365 · see citing works

Severity of Nonalcoholic Fatty Liver Disease and Progression to Cirrhosis Are Associated With Atherogenic Lipoprotein Profile

Siddiqui, M. S., Fuchs, M. A., Idowu, M. O., Luketic, V. A., Boyett, S. L., Sargeant, C., Stravitz, R. T., Puri, P., Matherly, S. C., Sterling, R. K., et al. (2014) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2014.10.008 · Cited by 231 · see citing works

Molecular Pathogenesis of NASH

Caligiuri, A., Gentilini, A., & Marra, F. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17091575 · Cited by 212 · see citing works

Experimental models of non-alcoholic fatty liver disease in rats

Kučera, O. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i26.8364 · Cited by 194 · see citing works

PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion

Morris, E. M., Meers, G. M.-E., Booth, F. W., Fritsche, K. L., Hardin, C. D., Thyfault, J. P., & Ibdah, J. A. (2012) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00169.2012 · Cited by 186 · see citing works

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

Pogribny, I. P., Starlard‐Davenport, A., Tryndyak, V., Han, T., Ross, S. A., Rusyn, I., & Beland, F. A. (2010) · Laboratory Investigation · doi:10.1038/labinvest.2010.113 · Cited by 185 · see citing works

Zonation of glucose and fatty acid metabolism in the liver: Mechanism and metabolic consequences

Hijmans, B. S., Grefhorst, A., Oosterveer, M. H., & Groen, A. K. (2013) · Biochimie · doi:10.1016/j.biochi.2013.06.007 · Cited by 169 · see citing works

Hydrogen sulfide and the liver

Mani, S., Cao, W., Wu, L., & Wang, R. (2014) · Nitric Oxide · doi:10.1016/j.niox.2014.02.006 · Cited by 158 · see citing works

Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK–mTOR–SREBP signaling pathway

Quan, H. Y., Kim, D. Y., Kim, S. J., Jo, H. K., Kim, G. W., & Chung, S. H. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.02.007 · Cited by 155 · see citing works

Nonalcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine

Arendt, B. M., David, W. L., Simons, B. L., Noureldin, S. A., Therapondos, G., Guindi, M. M., Sherman, M., & Allard, J. P. (2013) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2012-0261 · Cited by 154 · see citing works

Therapeutic Role of Ursolic Acid on Ameliorating Hepatic Steatosis and Improving Metabolic Disorders in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Rats

Li, S., Meng, F., Liao, X.-L., Wang, Y., Sun, Z., Guo, F., Li, X., Meng, M., Li, Y., & Sun, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086724 · Cited by 153 · see citing works

Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies

Geerling, J. J., Boon, M. R., Kooijman, S., Parlevliet, E. T., Havekes, L. M., Romijn, J. A., Meurs, I. M., & Rensen, P. C. N. (2014) · Journal of Lipid Research · doi:10.1194/jlr.r045013 · Cited by 137 · see citing works

Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men

Fukumitsu, S., Aida, K., Shimizu, H., & Toyoda, K. (2010) · Nutrition Research · doi:10.1016/j.nutres.2010.06.004 · Cited by 128 · see citing works

Ginsenoside Rb1 reduces fatty liver by activating AMP-activated protein kinase in obese rats

Shen, L., Xiong, Y., Wang, D. Q. ‐., Howles, P. N., Basford, J. E., Wang, J., Xiong, Y., Hui, D. Y., Woods, S. C., & Liu, M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m035907 · Cited by 127 · see citing works

Potential Therapeutic Application of Estrogen in Gender Disparity of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

Lee, C., Kim, J., & Jung, Y. (2019) · Cells · doi:10.3390/cells8101259 · Cited by 123 · see citing works

Differential Roles of Cell Death-inducing DNA Fragmentation Factor-α-like Effector (CIDE) Proteins in Promoting Lipid Droplet Fusion and Growth in Subpopulations of Hepatocytes

Xu, W., Wu, L., Yu, M., Chen, F., Arshad, M., Xia, X., Hao, R., Yu, J., Xu, L. M., Xu, D., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.701094 · Cited by 119 · see citing works

Fatty Acids - Induced Lipotoxicity and Inflammation

Savary, S., Trompier, D., Andreoletti, P., Le Borgne, F., Demarquoy, J., & Lizard, G. (2012) · Current Drug Metabolism · doi:10.2174/138920012803762729 · Cited by 111 · see citing works

Dendrobium officinale polysaccharide ameliorates the liver metabolism disorders of type II diabetic rats

Yang, J., Chen, H., Nie, Q., Huang, X., & Nie, S. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.08.007 · Cited by 110 · see citing works

Astaxanthin restricts weight gain, promotes insulin sensitivity and curtails fatty liver disease in mice fed a obesity-promoting diet

Bhuvaneswari, S., Elumalai, A., Viswanathan, P., & Anuradha, C. V. (2010) · Process Biochemistry · doi:10.1016/j.procbio.2010.05.016 · Cited by 107 · see citing works

Non-alcoholic fatty liver disease and metabolic syndrome in adolescents: Pathogenetic role of genetic background and intrauterine environment

Alisi, A., Cianfarani, S., Manco, M., Agostoni, C. V., & Nobili, V. (2011) · Annals of Medicine · doi:10.3109/07853890.2010.547869 · Cited by 107 · see citing works

Glycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-Inflammation

Yan, T., Wang, H., Cao, L.-J., Wang, Q., Takahashi, S., Yagai, T., Li, G.-L., Krausz, K., Wang, G.-J., Gonzalez, F., et al. (2018) · Drug Metabolism And Disposition · doi:10.1124/dmd.118.082008 · Cited by 97 · see citing works

Dietary d-limonene alleviates insulin resistance and oxidative stress–induced liver injury in high-fat diet and L-NAME-treated rats

Santiago, J. V. A., Jayaraman, J., Shenbagam, M., & Nalini, N. (2011) · European Journal of Nutrition · doi:10.1007/s00394-011-0182-7 · Cited by 103 · see citing works

Non-alcoholic Fatty Liver Disease in Lean Subjects: Characteristics and Implications

Kumar, R. K., & Mohan, S. (2017) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2016.00068 · Cited by 102 · see citing works

Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice

Bjørndal, B., Alterås, E. K., Lindquist, C., Svardal, A. M., Skorve, J., & Berge, R. K. (2018) · Nutrition & Metabolism · doi:10.1186/s12986-018-0241-7 · Cited by 100 · see citing works

Prebiotic approach alleviates hepatic steatosis: Implication of fatty acid oxidative and cholesterol synthesis pathways

Pachikian, B. D., Essaghir, A., Demoulin, J., Catry, É., Neyrinck, A. M., Dewulf, E. M., Sohet, F. M., Portois, L., Clerbaux, L., Carpentier, Y., et al. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200364 · Cited by 99 · see citing works

Brown Alga Ecklonia cava Polyphenol Extract Ameliorates Hepatic Lipogenesis, Oxidative Stress, and Inflammation by Activation of AMPK and SIRT1 in High-Fat Diet-Induced Obese Mice

Eo, H., Jeon, Y., Lee, M., & Lim, Y. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf502830b · Cited by 96 · see citing works

Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro

Jung, Y., Park, J., Kim, H., Sim, J., Youn, D., Kang, J., Lim, S., Jeong, M., Yang, W. M., Lee, S., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700231rr · Cited by 91 · see citing works

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

Bravo, E., Palleschi, S., Aspichueta, P., Buqué, X., Rossi, B., Cano, A., Napolitano, M., Ochoa, B., & Botham, K. M. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-60 · Cited by 91 · see citing works

In situ visualization of peroxisomal viscosity in the liver of mice with non-alcoholic fatty liver disease by near-infrared fluorescence and photoacoustic imaging

Zhou, Y., Li, P., Wang, X., Wu, C., Fan, N., Liu, X., Wu, L., Zhang, W., Zhang, W., Liu, Z., et al. (2020) · Chemical Science · doi:10.1039/d0sc02922j · Cited by 90 · see citing works

Multifactorial Basis and Therapeutic Strategies in Metabolism-Related Diseases

Guerra, J. V. D. S., Dias, M. M. G., Brilhante, A. J. V. C., Terra, M. F., García‐Arévalo, M., & Figueira, A. C. M. (2021) · Nutrients · doi:10.3390/nu13082830 · Cited by 87 · see citing works

Serum homocysteine levels, oxidative stress and cardiovascular risk in non-alcoholic steatohepatitis

Leach, N. V., Dronca, E., Vesa, Ș. C., Sâmpelean, D., Crăciun, E. C., Lupșor‐Platon, M., Crișan, D., Tarau, R., Rusu, R., Para, I., et al. (2014) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2014.09.007 · Cited by 83 · see citing works

Effect of aerobic exercise training on non-alcoholic fatty liver disease induced by a high fat diet in C57BL/6 mice

Cho, J., Lee, I., Kim, D.-H., Koh, Y., Kong, J., Lee, S. S., & Kang, H. (2014) · Physical Activity and Nutrition · doi:10.5717/jenb.2014.18.4.339 · Cited by 82 · see citing works

Osteocalcin improves nonalcoholic fatty liver disease in mice through activation of Nrf2 and inhibition of JNK

Du, J., Zhang, M., Lu, J., Zhang, X., Xiong, Q., Xu, Y., Bao, Y., & Jia, W. (2016) · Endocrine · doi:10.1007/s12020-016-0926-5 · Cited by 84 · see citing works

Apple peel polyphenols reduce mitochondrial dysfunction in mice with DSS-induced ulcerative colitis

Yeganeh, P. R., Leahy, J., Spahis, S., Patey, N., Desjardins, Y., Roy, D., DELVIN, E. E., Garofalo, C., Leduc‐Gaudet, J., St-Pierre, D., et al. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.03.008 · Cited by 82 · see citing works

Pediatric non-alcoholic fatty liver disease: Preventive andtherapeutic value of lifestyle intervention

Nobili, V., Alisi, A., & Raponi, M. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.6017 · Cited by 80 · see citing works

From chronic overfeeding to hepatic injury: Role of endoplasmic reticulum stress and inflammation

Mollica, M. P., Lionetti, L., Putti, R., Cavaliere, G., Gaita, M., & Barletta, A. (2011) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.10.012 · Cited by 80 · see citing works

Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN

Piguet, A., Stroka, D., Zimmermann, A., & Dufour, J. (2009) · Clinical Science · doi:10.1042/cs20090313 · Cited by 79 · see citing works

Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms

Yan, Z., Fan, R., Yin, S., Zhao, X., Liu, J., Li, L., Zhang, W., & Ge, L. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.05.054 · Cited by 78 · see citing works

Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet

Fraulob, J. C., Souza‐Mello, V., Águila, M. B., & Mandarim‐de‐Lacerda, C. A. (2012) · Clinical Science · doi:10.1042/cs20110373 · Cited by 75 · see citing works

Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport

Kawano, Y., Nishiumi, S., Tanaka, S., Nobutani, K., Miki, A., Yano, Y., Seo, Y., Kutsumi, H., Ashida, H., Azuma, T., et al. (2010) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2010.09.001 · Cited by 74 · see citing works

The Lactobacillus as a Probiotic: Focusing on Liver Diseases

Jeong, J., Park, H., Cha, M. G., Park, E., Won, S., Ganesan, R., Gupta, H., Gebru, Y. A., Sharma, S. P., Lee, S. B., et al. (2022) · Microorganisms · doi:10.3390/microorganisms10020288 · Cited by 74 · see citing works

Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis

Awad, A. S., Haleem, E. N. A. A., El‐Bakly, W. M., & Sherief, M. A. (2016) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-015-1207-1 · Cited by 73 · see citing works

Alisol A 24-Acetate Prevents Hepatic Steatosis and Metabolic Disorders in HepG2 Cells

Zeng, L., Tang, W., Yin, J., Feng, L., Li, Y., Yao, X., & Zhou, B. (2016) · Cellular Physiology and Biochemistry · doi:10.1159/000452560 · Cited by 72 · see citing works

Cherry Anthocyanins Regulate NAFLD by Promoting Autophagy Pathway

Chu, Q., Zhang, S., Chen, M., Han, W., Jia, R., Chen, W., & Zheng, X. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/4825949 · Cited by 72 · see citing works

Effect of methionine‐deficient and methionine‐supplemented diets on the hepatic one‐carbon and lipid metabolism in mice

Aissa, A. F., Tryndyak, V., de Conti, A., Melnyk, S., Gomes, T. D. U. H., Bianchi, M. L. P., James, S. J., Beland, F. A., Antunes, L. M. G., & Pogribny, I. P. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300726 · Cited by 67 · see citing works

Resveratrol Helps Recovery from Fatty Liver and Protects against Hepatocellular Carcinoma Induced by Hepatitis B Virus X Protein in a Mouse Model

Lin, H., Chen, Y., Hsu, W., Yang, C.-W., Kao, C., & Tsai, T. (2012) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-12-0001 · Cited by 66 · see citing works

Ursodeoxycholic Acid Ameliorates Fructose-Induced Metabolic Syndrome in Rats

Mahmoud, A. A. A., & Elshazly, S. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106993 · Cited by 66 · see citing works

The Positive Effects of Grifola frondosa Heteropolysaccharide on NAFLD and Regulation of the Gut Microbiota

Li, X., Zeng, F., Huang, Y., & Liu, B. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215302 · Cited by 64 · see citing works

Potential role of bioactive compounds of Phaseolus vulgaris L. on lipid-lowering mechanisms

Ramírez‐Jiménez, A. K., Reynoso‐Camacho, R., Tejero, M. E., León‐Galván, M. F., & Loarca-Piña, G. F. (2015) · Food Research International · doi:10.1016/j.foodres.2015.01.002 · Cited by 65 · see citing works

The Impacts of Herbal Medicines and Natural Products on Regulating the Hepatic Lipid Metabolism

Li, S., Xu, Y., Guo, W., Chen, F., Zhang, C., Tan, H. Y., Wang, N., & Feng, Y. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00351 · Cited by 64 · see citing works

Effects of taurine on growth performance, antioxidant capacity, and lipid metabolism in broiler chickens

Han, H., Zhang, J., Yan, E., Shen, M., Wu, J., Gan, Z., Wei, C., Zhang, L. L., & Wang, T. (2020) · Poultry Science · doi:10.1016/j.psj.2020.07.020 · Cited by 63 · see citing works

Mechanisms of Disease Progression in NASH

Bohinc, B. N., & Diehl, A. M. (2012) · Clinics in Liver Disease · doi:10.1016/j.cld.2012.05.002 · Cited by 62 · see citing works

Long-term bisphenol S exposure induces fat accumulation in liver of adult male zebrafish (Danio rerio) and slows yolk lipid consumption in F1 offspring

Wang, W., Zhang, X., Qin, J., Wei, P., Jia, Y., Wang, J., & Ru, S. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.01.020 · Cited by 62 · see citing works

Suboptimal maternal nutrition, during early fetal liver development, promotes lipid accumulation in the liver of obese offspring

Hyatt, M. A., Gardner, D. S., Sebert, S. P., Wilson, V., Davidson, N. J., Nigmatullina, Y., Chan, L. L. Y., Budge, H., & Symonds, M. E. (2010) · Reproduction · doi:10.1530/rep-10-0325 · Cited by 61 · see citing works

Mulberry extract inhibits oleic acid‐induced lipid accumulation via reduction of lipogenesis and promotion of hepatic lipid clearance

Ou, T., Hsu, M., Chan, K., Huang, C., Ho, H.-H., & Wang, C. (2011) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4489 · Cited by 61 · see citing works

Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats

Fan, H., Ma, X., Lin, P., Kang, Q., Zhao, Z., Wang, L., Sun, D., Cheng, J., & Li, Y. (2017) · Medical Science Monitor · doi:10.12659/msm.907530 · Cited by 61 · see citing works

Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society

Soresi, M., Noto, D., Cefalù, A., Martini, S., Vigna, G., Fonda, M., Manzato, E., Cattin, L., Fellin, R., Averna, M., et al. (2013) · Acta Diabetologica · doi:10.1007/s00592-012-0406-1 · Cited by 53 · see citing works

Resveratrol Attenuates High-Fat Diet Induced Hepatic Lipid Homeostasis Disorder and Decreases m6A RNA Methylation

Wu, J., Li, Y., Yu, J., Gan, Z., Wei, W., Wang, C., Zhang, L., Wang, T. Z., & Zhong, X. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.568006 · Cited by 60 · see citing works

Jaboticaba berry peel intake increases short chain fatty acids production and prevent hepatic steatosis in mice fed high-fat diet

Batista, Â. G., da Silva-Maia, J. K., Mendonça, M. C. P., Soares, E. S., Lima, G. C., Bogusz, S., da Cruz‐Höfling, M. A., & Maróstica, M. R. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.07.020 · Cited by 61 · see citing works

Carnosic acid (CA) prevents lipid accumulation in hepatocytes through the EGFR/MAPK pathway

Wang, T., Takikawa, Y., Tabuchi, T., Satoh, T., Kosaka, K., & Suzuki, K. (2012) · Journal of Gastroenterology · doi:10.1007/s00535-012-0546-7 · Cited by 58 · see citing works

Levels of Serum Ceruloplasmin Associate With Pediatric Nonalcoholic Fatty Liver Disease

Nobili, V., Siotto, M., Bedogni, G., Ravà, L., Pietrobattista, A., Panera, N., Alisi, A., & Squitti, R. (2012) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31827aced4 · Cited by 58 · see citing works

Effects of Antioxidants in Reducing Accumulation of Fat in Hepatocyte

Yang, J., Shin, J., Seo, S., Kim, S., Lee, S. H., & Shin, E. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092563 · Cited by 57 · see citing works

Schisandrin B: A Double‐Edged Sword in Nonalcoholic Fatty Liver Disease

Leong, P. K., & Ko, K. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/6171658 · Cited by 56 · see citing works

Antioxidant effects of Se-glutathione peroxidase in alcoholic liver disease

Shen, Y., Huang, H., Wang, Y., Yang, R., & Ke, X. (2022) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2022.127048 · Cited by 56 · see citing works

Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment

Vilà, L., Rebollo, A., Ađalsteisson, G. S., Alegret, M., Merlos, M., Roglans, N., & Laguna, J. C. (2010) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2010.11.011 · Cited by 55 · see citing works

High prevalence of diabetes mellitus in patients with liver cirrhosis

Wlazlo, N., Beijers, H. J. B. H., Schoon, E. J., Sauerwein, H. P., Stehouwer, C. D. A., & Bravenboer, B. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03093.x · Cited by 54 · see citing works

Antidiabetic effects of different polysaccharide fractions from Artemisia sphaerocephala Krasch seeds in db/db mice

Li, J., Zhao, H., Hu, X., Shi, J., Shao, D., & Jin, M. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.01.002 · Cited by 54 · see citing works

Chronic exposure to tetrabromodiphenyl ether (BDE-47) aggravates hepatic steatosis and liver fibrosis in diet-induced obese mice

Yang, C., Zhu, L., Kang, Q., Lee, H. K., Li, D., Chung, A. C. K., & Cai, Z. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.120766 · Cited by 54 · see citing works

Activation of Male Liver Chromatin Accessibility and STAT5-Dependent Gene Transcription by Plasma Growth Hormone Pulses

Connerney, J., Lau-Corona, D., Rampersaud, A., & Waxman, D. J. (2017) · Endocrinology · doi:10.1210/en.2017-00060 · Cited by 53 · see citing works

Complexity of microRNA function and the role of isomiRs in lipid homeostasis

Vickers, K. C., Sethupathy, P., Baran‐Gale, J., & Remaley, A. T. (2013) · Journal of Lipid Research · doi:10.1194/jlr.r034801 · Cited by 51 · see citing works

The prevalence of non-alcoholic fatty liver disease and metabolic syndrome in obese children

Gupta, R., Bhangoo, A., Matthews, N., Anhalt, H., Matta, Y., Lamichhane, B., Malik, S., Narwal, S., Wetzler, G., & Ten, S. (2011) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2011.282 · Cited by 51 · see citing works

Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis

Bernal, C., Martín‐Pozuelo, G., Lozano, A. B., Sevilla, A., García‐Alonso, J., Cánovas, M., & Periago, M. J. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.05.003 · Cited by 53 · see citing works

Treatment options for hypertriglyceridemia: From risk reduction to pancreatitis

Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., & Stalenhoef, A. (2014) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.10.002 · Cited by 50 · see citing works

Adzuki bean ameliorates hepatic lipogenesis and proinflammatory mediator expression in mice fed a high-cholesterol and high-fat diet to induce nonalcoholic fatty liver disease

Kim, S., Hong, J., Jeon, R., & Kim, H.-S. (2015) · Nutrition Research · doi:10.1016/j.nutres.2015.11.002 · Cited by 50 · see citing works

Normal weight dyslipidemia: Is it all about the liver?

Ipsen, D. H., Tveden‐Nyborg, P., & Lykkesfeldt, J. (2016) · Obesity · doi:10.1002/oby.21443 · Cited by 51 · see citing works

Untargeted metabonomics reveals intervention effects of chicory polysaccharide in a rat model of non-alcoholic fatty liver disease

Zhu, H., Wang, Z., Wu, Y., Jiang, H., Zhou, F., Xie, X., Wang, R., & Hua, C. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.01.141 · Cited by 50 · see citing works

HIV protease inhibitors and obesity

Anuurad, E., Bremer, A. A., & Berglund, L. (2010) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e32833dde87 · Cited by 50 · see citing works

Interaction between metformin and leucine in reducing hyperlipidemia and hepatic lipid accumulation in diet-induced obese mice

Fu, L., Bruckbauer, A., Li, F., Cao, Q., Cui, X., Wu, R., Shi, H., Zemel, M. B., & Xue, B. (2015) · Metabolism · doi:10.1016/j.metabol.2015.07.006 · Cited by 49 · see citing works

Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism

Ni, H.-Y., Yu, L., Zhao, X., Wang, L., Zhao, C., Huang, H. F., Zhu, H.-L., Efferth, T., Gu, C., & Fu, Y. (2022) · Phytomedicine · doi:10.1016/j.phymed.2021.153919 · Cited by 48 · see citing works

Nonalcoholic Fatty Liver in Children and Adolescents: An Overview

Corte, C. D., Alisi, A., Saccari, A., Vito, R. D., Vania, A., & Nobili, V. (2012) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2012.01.010 · Cited by 48 · see citing works

A theoretical study of lipid accumulation in the liver—implications for nonalcoholic fatty liver disease

Schleicher, J., Guthke, R., Dahmen, U., Dirsch, O., Holzhütter, H., & Schuster, S. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.08.016 · Cited by 48 · see citing works

The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding

Henriksen, B. S., Curtis, M. E., Fillmore, N., Cardon, B. R., Thomson, D. M., & Hancock, C. R. (2013) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-5-29 · Cited by 48 · see citing works

Cordycepin attenuates high-fat diet-induced non-alcoholic fatty liver disease via down-regulation of lipid metabolism and inflammatory responses

Gong, X., Tian-ju, L., Wan, R., & Sha, L. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.107173 · Cited by 48 · see citing works

Developmental origins of health and disease: experimental and human evidence of fetal programming for metabolic syndrome

Correia, M. L., Volpato, A. M., Águila, M. B., & Mandarim‐de‐Lacerda, C. A. (2011) · Journal of Human Hypertension · doi:10.1038/jhh.2011.61 · Cited by 47 · see citing works

Silybum marianum oil attenuates hepatic steatosis and oxidative stress in high fat diet-fed mice

Zhu, S. Y., Jiang, N., Yang, J., Tu, J., Zhou, Y. H., Xiao, X., & Dong, Y. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.144 · Cited by 47 · see citing works

Thyroid hormone analogues and derivatives: Actions in fatty liver

Coppola, M. (2014) · World Journal of Hepatology · doi:10.4254/wjh.v6.i3.114 · Cited by 46 · see citing works

Association between metabolic abnormalities and HBV related hepatocelluar carcinoma in Chinese: A cross-sectional study

Zhao, J., Zhao, Y., Wang, H., Gu, X., Ji, J., & Gao, C. (2011) · Nutrition Journal · doi:10.1186/1475-2891-10-49 · Cited by 46 · see citing works

A polyphenol extract modifies quantity but not quality of liver fatty acid content in high-fat–high-sucrose diet-fed rats: possible implication of the sirtuin pathway

Aoun, M., Michel, F., Fouret, G., Casas, F., Jullien, M., Wrutniak‐Cabello, C., Ramos, J., Cristol, J., Coudray, C., Carbonneau, M., et al. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510002850 · Cited by 46 · see citing works

The Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic Fatty Liver Disease

Feldman, A., Aigner, E. S., Weghuber, D., & Paulmichl, K. (2015) · BioMed Research International · doi:10.1155/2015/287401 · Cited by 45 · see citing works

The Role of Liver Zonation in Physiology, Regeneration, and Disease

Panday, R., Monckton, C. P., & Khetani, S. R. (2022) · Seminars in Liver Disease · doi:10.1055/s-0041-1742279 · Cited by 44 · see citing works

Circadian Rhythms in Liver Physiology and Liver Diseases

Tong, X., & Yin, L. (2013) · Comprehensive physiology · doi:10.1002/cphy.c120017 · Cited by 48 · see citing works

Way back for fructose and liver metabolism: Bench side to molecular insights

Rebollo, A. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i45.6552 · Cited by 44 · see citing works

Immunohistochemical study of the autophagy marker microtubule‐associated protein 1 light chain 3 in normal and steatotic human livers

Kashima, J., Shintani‐Ishida, K., Nakajima, M., Maeda, H., Unuma, K., Uchiyama, Y., & Yoshida, K. (2013) · Hepatology Research · doi:10.1111/hepr.12183 · Cited by 43 · see citing works

Dyslipidemia: Obese or Not Obese—That Is Not the Question

Ipsen, D. H., Tveden‐Nyborg, P., & Lykkesfeldt, J. (2016) · Current Obesity Reports · doi:10.1007/s13679-016-0232-9 · Cited by 42 · see citing works

Coumarin attenuates hepatic steatosis by down-regulating lipogenic gene expression in mice fed a high-fat diet

Um, M. Y., Moon, M. K., Ahn, J., & Ha, T. Y. (2013) · British Journal Of Nutrition · doi:10.1017/s0007114512005260 · Cited by 42 · see citing works

Molecular pathways in non-alcoholic fatty liver disease

Auguet, T., Berlanga, A., Guiu‐Jurado, E., & Porras, J. A. (2014) · Clinical and Experimental Gastroenterology · doi:10.2147/ceg.s62831 · Cited by 380 · see citing works

Non-Alcoholic Fatty Liver Disease

Engin, A. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-48382-5_19 · Cited by 247 · see citing works

Molecular mechanisms of steatosis in nonalcoholic fatty liver disease.

Pettinelli, P., Obregón, A. M., & Videla, L. A. (2011) · PubMed · doi:10.1590/s0212-16112011000300003 · Cited by 75 · see citing works

Non alcoholic fatty liver disease: pathogenesis, role of (TNF-α, IL-6) in hepatic inflammation and future potential nutraceutical treatment

Faheem, S. A., Saeed, N. M., El‐Naga, R. N., & Azab, S. S. (2019) · Archives of Pharmaceutical Sciences Ain Shams University · doi:10.21608/aps.2019.17201.1012

Pathophysiology of NAFLD

(2017) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9781681084657117010008