Cited by 10Optical Imaging and Spectroscopy TechniquesPhotoacoustic and Ultrasonic ImagingInfrared Thermography in Medicine

Deep learning: step forward to high‐resolution in vivo shortwave infrared imaging

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Baulin, Vladimir A., Usson, Yves, Le Guével, Xavier·2021·Journal of Biophotonics

Abstract

Shortwave infrared window (SWIR: 1000–1700 nm) represents a major improvement compared to the NIR‐I region (700–900 nm) in terms of temporal and spatial resolutions in depths down to 4 mm. SWIR is a fast and cheap alternative to more precise methods such as X‐ray and opto‐acoustic imaging. Main obstacles in SWIR imaging are the noise and scattering from tissues and skin that reduce the precision of the method. We demonstrate that the combination of SWIR in vivo imaging in the NIR‐IIb region (1500–1700 nm) with advanced deep learning image analysis allows to overcome these obstacles and making a large step forward to high resolution imaging: it allows to precisely segment vessels from tissues and noise, provides morphological structure of the vessels network, with learned pseudo‐3D shape, their relative position, dynamic information of blood vascularization in depth in small animals and distinguish the vessels types: artieries and veins. For demonstration we use neural network IterNet that exploits structural redundancy of the blood vessels, which provides a useful analysis tool for raw SWIR images.

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Crossref · 10.1002/jbio.202100102

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Authors
Baulin, V. A., Usson, Y., & Le Guével, X.
Affiliations
  • Universitat Rovira i Virgili (ES)
  • Translational Innovation in Medicine and Complexity (FR)
  • Cancer Targets and Experimental Therapeutics, Cancer Targets and Experimental Therapeutics University of Grenoble Alpes Grenoble France
Corresponding author
Baulin, Vladimir A.
Venue
Journal of Biophotonics
Publisher
Wiley
Published
2021-05-12
Volume
14
Issue
7
Pages
e202100102-e202100102
ISSN
  • 1864-063X (ISSN-L)
  • 1864-0648
OpenAlex
W3158432244
Cited by
10
References
26
Citations by year
2026: 1 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 1
FWCI
1.06
Type
journal article
Language
en
Open access
Locations
  • Journal of Biophotonics (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
Funders
  • Agence Nationale de la Recherche
  • Plan National Cancer
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Infrared Thermography in Medicine
Keywords
short-wave infrared imaging, in vivo imaging, deep learning, vessel segmentation, small animal imaging, vascularization
MeSH terms
Deep Learning, Animals, Infrared Rays, Radio Waves, Neural Networks, Computer

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