Delivery of Therapeutic Proteins

Recent advances with liposomes as pharmaceutical carriers

Torchilin, V. P. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1632 · Cited by 5,282

Drug Delivery Systems: Entering the Mainstream

Allen, T. M., & Cullis, P. R. (2004) · Science · doi:10.1126/science.1095833 · Cited by 4,552

Biodegradable polymeric nanoparticles as drug delivery devices

Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00339-4 · Cited by 3,549

Effect of pegylation on pharmaceuticals

Harris, J. M., & Chess, R. B. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1033 · Cited by 3,431

The dawning era of polymer therapeutics

Duncan, R. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1088 · Cited by 3,312

Biodegradable Long-Circulating Polymeric Nanospheres

Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V. S., Torchilin, V. P., & Langer, R. (1994) · Science · doi:10.1126/science.8128245 · Cited by 2,951

An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System

Mazmanian, S. K., Liu, C. H., Tzianabos, A. O., & Kasper, D. L. (2005) · Cell · doi:10.1016/j.cell.2005.05.007 · Cited by 2,910

PEGylation, successful approach to drug delivery

Veronese, F. M., & Pasut, G. (2005) · Drug Discovery Today · doi:10.1016/s1359-6446(05)03575-0 · Cited by 2,344

Chemistry for peptide and protein PEGylation

Roberts, M. J., Bentley, M. D., & Harris, J. M. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00022-4 · Cited by 1,628

Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol.

Abuchowski, A., Es, T. V., Palczuk, N. C., & Davis, F. F. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40291-2 · Cited by 1,358

Long-circulating poly(ethylene glycol)-coated poly(lactid-co-glycolid) microcapsules as potential carriers for intravenously administered drugs

Ferenz, K. B., Waack, I. N., Mayer, C., de GROOT, H., & Kirsch, M. (2013) · Journal of Microencapsulation · doi:10.3109/02652048.2013.770098 · Cited by 18

Catalytic and thermodynamic properties of glycosylated Bacillus cereus cyclodextrin glycosyltransferase

Abdel–Naby, M. A., Fouad, A. A., & El-Refai, H. A. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.02.017 · Cited by 17

PEGylation and Cell-Penetrating Peptides: Glimpse into the Past and Prospects in the Future

Kumar, S., Singh, D., Kumari, P., Malik, R. S., Poonam, P., Parang, K., & Tiwari, R. K. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200128142603 · Cited by 17

Tumor-Targeting Liposomes with Transient Holes Allowing Intact Rituximab Internally

Kim, Y., Youn, Y. S., Oh, K. T., Kim, D., & Lee, E. S. (2020) · Biomacromolecules · doi:10.1021/acs.biomac.0c01514 · Cited by 17

Enzyme Engineering Strategies for the Bioenhancement of l-Asparaginase Used as a Biopharmaceutical

Miranda, J., Lefin, N., Beltrán, J. F., Belén, L. H., Tsipa, A., Farías, J. G., & Zamorano, M. (2023) · BioDrugs · doi:10.1007/s40259-023-00622-5 · Cited by 17

Synthesis of N-Terminally Linked Protein and Peptide Dimers by Native Chemical Ligation

Xiao, J., Hamilton, B. S., & Tolbert, T. J. (2010) · Bioconjugate Chemistry · doi:10.1021/bc100370j · Cited by 17

Lipids and inorganic nanoparticles in oral insulin delivery

Sonia, T. A., & Sharma, C. P. (2014) · Elsevier eBooks · doi:10.1533/9781908818683.219 · Cited by 17

MPET 2 : a multi-network poroelastic and transport theory for predicting absorption of monoclonal antibodies delivered by subcutaneous injection

Wang, H., Hu, T., Leng, Y., de Lucio, M., & Gómez, H. (2023) · Drug Delivery · doi:10.1080/10717544.2022.2163003 · Cited by 17

Safety of poly (ethylene glycol)-coated perfluorodecalin-filled poly (lactide-co-glycolide) microcapsules following intravenous administration of high amounts in rats

Ferenz, K. B., Waack, I. N., Laudien, J., Mayer, C., Broecker‐Preuss, M., de GROOT, H., & Kirsch, M. (2014) · Results in Pharma Sciences · doi:10.1016/j.rinphs.2014.04.001 · Cited by 16

Pharmacokinetic and pharmacodynamic profiles of recombinant human erythropoietin-loaded poly(lactic-co-glycolic acid) microspheres in rats

Zhou, X., He, J., Du, H.-J., Fan, Y.-Y., Wang, Y., Zhang, H., & Jiang, Y. (2011) · Acta Pharmacologica Sinica · doi:10.1038/aps.2011.157 · Cited by 16

New treatments in hemophilia: insights for the clinician

Knobe, K. E., & Berntorp, E. E. (2012) · Therapeutic Advances in Hematology · doi:10.1177/2040620712440007 · Cited by 16

Effect of cationic grafted copolymer structure on the encapsulation of bovine serum albumin

Flynn, N. H., Topal, Ç. Ö., Koralege, R. S. H., Hartson, S. D., Ranjan, A., Liu, J., Pope, C., & Ramsey, J. D. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.01.092 · Cited by 16

Insight into Heterogeneous Distribution of Protein Aggregates at the Surface Layer Using Attenuated Total Reflection-Fourier Transform Infrared Spectroscopic Imaging

Tiernan, H., Byrne, B., & Kazarian, S. G. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c00250 · Cited by 16

Nanocarriers for protein and peptide delivery: Recent advances and progress

-, S. S. V. S. B. B. (2021) · Journal of Research in Pharmacy · doi:10.29228/jrp.1 · Cited by 15

Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity

Honda, Y., Nomoto, T., Matsui, M., Takemoto, H., Miura, Y., & Nishiyama, N. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c20188 · Cited by 16

Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology

Sakr, O. S., Jordan, O., & Borchard, G. (2015) · Drug Delivery · doi:10.3109/10717544.2015.1069422 · Cited by 16

Sensitivity of PEGylated Interferon Detection by Anti-Polyethylene Glycol (PEG) Antibodies Depends on PEG Length

Cheng, T.-C., Chuang, K.-H., Chen, M. J., Wang, H.-E., Tzou, S., Su, Y.-C., Chuang, C., Kao, C.-H., Chen, B., Chang, L., et al. (2013) · Bioconjugate Chemistry · doi:10.1021/bc3006144 · Cited by 16

Efficacy of gene-therapy based on adenovirus encoding granulocyte-macrophage colony-stimulating factor in drug-sensitive and drug-resistant experimental pulmonary tuberculosis

Francisco‐Cruz, A., Mata‐Espinosa, D., Ramos‐Espinosa, O., Marquina‐Castillo, B., Estrada-Parra, S. A., Xing, Z., & Hernández‐Pando, R. (2016) · Tuberculosis · doi:10.1016/j.tube.2016.05.015 · Cited by 16

Poly-3-Hydroxybutyrate Functionalization with BioF-Tagged Recombinant Proteins

Bello‐Gil, D., Maestro, B., Fonseca, J., Dinjaski, N., Prieto, M. A., & Sanz, J. M. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.02595-17 · Cited by 16

Therapeutic protein and drug imprinted nanostructures as controlled delivery tools

Yavuz, H., Çetin, K., Akgönüllü, S., Battal, D., & Deni̇zli̇, A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813627-0.00012-0 · Cited by 16

Randomized controlled clinical trial of polyethylene glycol recombinant human granulocyte colony-stimulating factor in the treatment of neutropenia after chemotherapy for breast cancer

Huang, W., Liu, J., Yi, Z., Wu, F., Li, N., Chen, K., Yi, H., Wang, L., Zhen, H., & Lin, L. (2018) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-018-3639-z · Cited by 17

Functional Hydrogels: A Promising Platform for Biomedical and Environmental Applications

Quazi, M. Z., Quazi, A. S., Song, Y., & Park, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26189066 · Cited by 18

Biopharmaceutical nanoclusters: Towards the self-delivery of protein and peptide therapeutics

Danielsen, M., Hempel, C., Andresen, T. L., & Urquhart, A. J. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.04.050 · Cited by 15

Immobilized nanoparticles-mediated enzyme therapy; promising way into clinical development

Zangi, A. R., Amiri, A., Borzouee, F., Bagherifar, R., Pazooki, P., Hamishehkar, H., & Javadzadeh, Y. (2023) · Discover Nano · doi:10.1186/s11671-023-03823-7 · Cited by 18

Induction of Cancer Cell Death by Hyaluronic Acid-Mediated Uptake of Cytochrome C

Morales-Cruz, C. M. F. M., & Suarez, B. (2015) · Journal of Nanomedicine & Nanotechnology · doi:10.4172/2157-7439.1000316 · Cited by 15

Type I pig collagen enhances the efficacy of PEDF 34-mer peptide in a mouse model of laser-induced choroidal neovascularization

Kim, H. W., Roh, K.-H., Kim, S. W., Park, S. J., Lim, N.-Y., Jung, H., Choi, I., & Park, S. (2019) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-019-04394-z · Cited by 15

A DNA Vaccine Delivery Platform Based on Elastin-Like Recombinamer Nanosystems for Rift Valley Fever Virus

González‐Valdivieso, J., Borrego, B., Girotti, A., Moreno, S., Brun, A., Bermejo-Martín, J. F., & Arias, F. J. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00054 · Cited by 15

Treating brain diseases using systemic parenterally-administered protein therapeutics: Dysfunction of the brain barriers and potential strategies

Zaghmi, A., Drouin‐Ouellet, J., Brambilla, D., & Gauthier, M. A. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120461 · Cited by 17

Alternative Activation of Macrophages through Interleukin-13-Loaded Extra-Large-Pore Mesoporous Silica Nanoparticles Suppresses Experimental Autoimmune Encephalomyelitis

Park, J., Choi, S. W., Cha, B. G., Kim, J., & Kang, S. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00946 · Cited by 17

Polymers in oral insulin delivery

Sonia, T. A., & Sharma, C. P. (2014) · Elsevier eBooks · doi:10.1533/9781908818683.257 · Cited by 15

Phenyl Amide Linker Improves the Pharmacokinetics and Pharmacodynamics of N-Terminally Mono-PEGylated Human Growth Hormone

Wu, L., Ji, S., Shen, L., & Hu, T. (2014) · Molecular Pharmaceutics · doi:10.1021/mp500266c · Cited by 14

Delivery of Peptides and Proteins via Long Acting Injections and Implants

Stevenson, C. L., Rhodes, C. A., & Prestrelski, S. J. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0554-2_20 · Cited by 14

NANOMATERIALS FOR PROTEIN-MEDIATED THERAPY AND DELIVERY

Barry, J., & Vertegel, A. A. (2013) · Nano LIFE · doi:10.1142/s1793984413430010 · Cited by 14

Smart Release Nano-formulation of Cytochrome C and Hyaluronic Acid Induces Apoptosis in Cancer Cells

Figueroa, C. M., Suarez, B., Molina, A. M., Jc, F., Torres-Rivera, Z. J., & Griebenow, K. H. (2017) · Journal of Nanomedicine & Nanotechnology · doi:10.4172/2157-7439.1000427 · Cited by 14

Enhanced Adsorption of a Protein–Nanocarrier Complex onto Cell Membranes through a High Freeze Concentration by a Polyampholyte Cryoprotectant

Ahmed, S. G., Miyawaki, O., & Matsumura, K. (2018) · Langmuir · doi:10.1021/acs.langmuir.7b03622 · Cited by 14

Liposomal Drug Delivery System-A Review

Deepthi, V., & Kavitha, A. N. (2014) · Rajiv Gandhi University of Health Sciences Journal of Pharmaceutical Sciences · doi:10.5530/rjps.2014.2.3 · Cited by 13

Delivery of Therapeutic Proteins Using Electrospun Fibers—Recent Developments and Current Challenges

Seif, S., Planz, V., & Windbergs, M. (2017) · Archiv der Pharmazie · doi:10.1002/ardp.201700077 · Cited by 13

Barnase encapsulation into submicron porous CaCO 3 particles: studies of loading and enzyme activity

Yashchenok, A. M., Gusliakova, О. I., Коновалова, Е. В., Novoselova, M. V., Shipunova, V. O., Abakumova, T. O., Efimova, O., Kholodenko, R. V., Schulga, A. A., Zatsepin, T. S., et al. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb01315g · Cited by 13

Retention of modified BSA by ultrafiltration membranes

Levitsky, I., Dahan, Y., Arkhangelsky, E., & Gitis, V. (2014) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.4588 · Cited by 13

Self-Assembly of Colloidosome Shells on Drug-Containing Hydrogels

Rosenberg, R. T., & Dan, N. R. (2011) · Journal of Biomaterials and Nanobiotechnology · doi:10.4236/jbnb.2011.21001 · Cited by 13

The Delivery of Drugs – Peptides and Proteins

Schiffter, H. A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-08-088504-9.00338-x · Cited by 13

Systematic evaluation of pH and thermoresponsive poly(n-isopropylacrylamide-chitosan-fluorescein) microgel

Hernández, P., Lucero‐Acuña, A., Gutiérrez-Valenzuela, C. A., Moreno-Corral, R. A., & Esquivel, R. (2017) · e-Polymers · doi:10.1515/epoly-2016-0328 · Cited by 13

Kidney-Specific Drug Delivery: Review of Opportunities, Achievements, and Challenges

Sarko, D. (2016) · Journal of Analytical & Pharmaceutical Research · doi:10.15406/japlr.2016.02.00033 · Cited by 13

Microparticles Locally Deliver Active Interleukin‐1 Receptor Antagonist In Vivo

Clements, A. E. B., Groves, E. R., Chamberlain, C. S., Vanderby, R., & Murphy, W. L. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800263 · Cited by 13

The Current Landscape of Novel Formulations and the Role of Mathematical Modeling in Their Development

Cottura, N., Howarth, A., Rajoli, R. K. R., & Siccardi, M. (2020) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.1715 · Cited by 13

Half‐Life Modulating Strategies–An Introduction

Kontermann, R. E. (2012) · Wiley eBooks · doi:10.1002/9783527644827.ch1 · Cited by 15

High throughput onion-like liposome formation with efficient protein encapsulation under flash antisolvent mixing

Zhan, Q.-W., Gao, J., Li, D., & Huang, Y. (2022) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2022.03.043 · Cited by 12

Amphiphilic Polypeptides Obtained by Post-Polymerization Modification of Poly-l-Lysine as Systems for Combined Delivery of Paclitaxel and siRNA

Dzhuzha, A. Y., Gandalipov, E. R., Korzhikov-Vlakh, V. A., Katernyuk, E., Захарова, Н. В., Silonov, S. A., Tennikova, T. B., & Korzhikova‐Vlakh, E. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041308 · Cited by 12

Specific surface, crystallinity, and dissolution of lyophilized fibrinogen. A study by combined small- and wide-angle X-ray scattering (SWAXS)

Wahl, V., Saurugger, E., Khinast, J., & Laggner, P. (2014) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2014.12.018 · Cited by 12

Sterile dosage forms loaded nanosystems for parenteral, nasal, pulmonary and ocular administration

Ahmed, T. A., El‐Say, K. M., Ahmed, O. A. A., & Zidan, A. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813629-4.00009-7 · Cited by 12

Silica-Based Nanoparticles for Protein Encapsulation and Delivery

Begarani, F., Cassano, D., Margheritis, E. G., Marotta, R., Cardarelli, F., & Voliani, V. (2018) · Nanomaterials · doi:10.3390/nano8110886 · Cited by 12

Thermally Assisted Generation of Protein–Poly(ethylene sodium phosphate) Conjugates with High Mineral Affinity

Noree, S., & Iwasaki, Y. (2019) · ACS Omega · doi:10.1021/acsomega.8b03585 · Cited by 12

Profile of PEGylated interferon beta in the treatment of relapsing-remitting multiple sclerosis

Cocco, E. E., & Marrosu, M. G. (2015) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s69123 · Cited by 12

Lipid and PLGA Microparticles for Sustained Delivery of Protein and Peptide Drugs

Wu, C., & Mu, H. (2019) · Pharmaceutical Nanotechnology · doi:10.2174/2211738507666191029160944 · Cited by 12

Lipid modification of staphylokinase and its implications on stability and activity

Mannully, S. T., Shanthi, C., & Pulicherla, K. K. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.10.134 · Cited by 11

Formulation and In Vitro Characterization of PLGA/PLGA-PEG Nanoparticles Loaded with Murine Granulocyte-Macrophage Colony-Stimulating Factor

Mihalik, N. E., Wen, S., Driesschaert, B., & Eubank, T. D. (2021) · AAPS PharmSciTech · doi:10.1208/s12249-021-02049-z · Cited by 11

Controlling and quantifying the stability of amino acid-based cargo within polymeric delivery systems

Souery, W. N., Kumar, S. A., Prasca-Chamorro, D., Moore, D. M., Good, J., & Bishop, C. J. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.02.042 · Cited by 11

Insights on the Formulation of Recombinant Proteins

Ribeiro, R., Abreu, T. R., Silva, A. C., Gonçalves, J., & Moreira, J. N. (2019) · Advances in biochemical engineering, biotechnology · doi:10.1007/10_2019_119 · Cited by 11

Overcoming barriers confronting application of protein therapeutics in bone fracture healing

Czech, T., & Oyewumi, M. O. (2020) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00829-x · Cited by 11

Insulin Release from NPH Insulin-Loaded Pluronic® F127 Hydrogel in the Presence of Simulated Tissue Enzyme Activity

Sultan, M. H., Mahdi, W. A., & Kwon, Y. M. (2020) · Processes · doi:10.3390/pr8101320 · Cited by 11

Characterization of 40 kDa poly(ethylene glycol) polymers by proton transfer reaction QTOF mass spectrometry and 1H-NMR spectroscopy

Malmstrøm, J. (2012) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-012-5942-6 · Cited by 11

Nanostructures of whey proteins for encapsulation of food ingredients

Ramos, Ó. L., Pereira, R. N., Simões, L. S., Madalena, D. A., Rodrigues, R. M. M., Teixeira, J. A., & Vicente, A. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815663-6.00003-3 · Cited by 11

Protein charge parameters that influence stability and cellular internalization of polyelectrolyte complex micelles

Kapelner, R. A., Fisher, R. S., Elbaum‐Garfinkle, S., & Obermeyer, A. C. (2022) · Chemical Science · doi:10.1039/d2sc00192f · Cited by 11

Amphiphilic Cell-Penetrating Peptides Containing Arginine and Hydrophobic Residues as Protein Delivery Agents

Moreno, J., Zoghebi, K. A., Salehi, D., Kim, L., Shoushtari, S. K., Tiwari, R. K., & Parang, K. (2023) · Pharmaceuticals · doi:10.3390/ph16030469 · Cited by 10

Modification with polysialic acid–PEG copolymer as a new method for improving the therapeutic efficacy of proteins

Wu, J., Lu, S., Zheng, Z., Zhu, L., & Zhan, X. (2016) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2015.1135463 · Cited by 10

Investigation of thermal denaturation of solid bovine serum albumin by terahertz dielectric spectroscopy

Li, X., Fu, X., Liu, J., Du, Y., & Hong, Z. (2013) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2013.06.048 · Cited by 10

Introduction into Formulation Development of Biologics

Weinbuch, D., Hawe, A., Jiskoot, W., & Frieß, W. (2018) · AAPS advances in the pharmaceutical sciences series · doi:10.1007/978-3-319-90603-4_1 · Cited by 10

Temperature-induced aggregation behavior in bovine pancreas trypsin solutions

Trampari, S., Papagiannopoulos, A., & Pispas, S. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.05.124 · Cited by 10

Targeted Delivery of Recombinant Heat Shock Protein 27 to Cardiomyocytes Promotes Recovery from Myocardial Infarction

Kim, N., Ullah, I., Chung, K., Lee, D., Cha, M., Ban, H., Choi, C. S., Kim, S., Hwang, K.-C., Kumar, P., et al. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00192 · Cited by 10

Advances in Supportive Care for Acute Lymphoblastic Leukemia

Cook, J., & Litzow, M. R. (2020) · Current Hematologic Malignancy Reports · doi:10.1007/s11899-020-00585-2 · Cited by 11

Clinical and demographic factors contributing to asparaginase-associated toxicities in children with acute lymphoblastic leukemia

Dharia, P., Swartz, M. D., Bernhardt, M. B., Chen, H., Gramatges, M. M., Lupo, P. J., Brown, A. L., & Scheurer, M. E. (2022) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2022.2102621 · Cited by 10

Extraction of PLGA-Microencapsulated Proteins Using a Two-Immiscible Liquid Phases System Containing Surfactants

Saez, V. M., Ramón, J., Caballero, L., Aldana, R., Cruz, E., Peniche-Covas, C., & Páez, R. (2012) · Pharmaceutical Research · doi:10.1007/s11095-012-0916-0 · Cited by 10

Osmogen‐Mediated One‐Step Technique of Fabricating Hollow Microparticles for Encapsulation and Delivery of Bioactive Molecules

Kharel, S., Lee, W., Lee, X. Y., & Loo, S. C. J. (2016) · Macromolecular Bioscience · doi:10.1002/mabi.201600328 · Cited by 10

Surface Interactions between Boundary Layers of Poly(ethylene oxide)–Liposome Complexes: Lubrication, Bridging, and Selective Ligation

Angayarkanni, S. A., Kampf, N., & Klein, J. E. (2019) · Langmuir · doi:10.1021/acs.langmuir.9b01708 · Cited by 10

A genipin-crosslinked protein–polymer hybrid system for the intracellular delivery of ribonuclease A

Liang, X., Tang, X., Yang, J., Zhang, J., Han, H., & Li, Q. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s210486 · Cited by 10

Chemopreventive role of proteins and polysaccharides from Pleurotus tuber-regium

Abdullah, E., Amirullah, N. A., Vijayan, H., Rashid, N. A., Abdullah, N., & Abidin, N. Z. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.104311 · Cited by 9

Release and pharmacokinetics of near-infrared labeled albumin from monodisperse poly(d,l-lactic-co-hydroxymethyl glycolic acid) microspheres after subcapsular renal injection

Kazazi-Hyseni, F., van Vuuren, S. H., van der Giezen, D. M., Pieters, E. H. E., Ramazani, F., Rodríguez, S., Veldhuis, G. J., Goldschmeding, R., van Nostrum, C. F., Hennink, W. E., et al. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.04.030 · Cited by 9

Molecular screening and genetic diversity analysis of anticancer Azurin-encoding and Azurin-like genes in human gut microbiome deduced through cultivation-dependent and cultivation-independent studies

Nguyễn, V. D., Nguyen, T. T., Pham, T. T., Packianather, M., & Le, C. H. (2019) · International Microbiology · doi:10.1007/s10123-019-00070-8 · Cited by 9

Protein Encapsulation of Experimental Anticancer Agents 5F 203 and Phortress: Towards Precision Drug Delivery

Breen, A. F., Scurr, D. J., Cassioli, M. L., Wells, G., Thomas, N. R., Zhang, J., Turyanska, L., & Bradshaw, T. D. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s226293 · Cited by 9

A cell-penetrating peptide suppresses the hypoxia inducible factor-1 function by binding to the helix-loop-helix domain of the aryl hydrocarbon receptor nuclear translocator

Wang, Y., Thompson, J., & Chan, W. K. (2013) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2013.02.003 · Cited by 9

High-throughput in vitro drug release and pharmacokinetic simulation as a tool for drug delivery system development: Application to intravitreal ocular administration

Sarkhel, S., Ramsay, E., Kontturi, L.-S., Peltoniemi, J., & Urtti, A. O. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.10.062 · Cited by 9

Polymer-based Vehicles for Therapeutic Peptide Delivery

Zhang, J., Desale, S. S., & Bronich, T. K. (2015) · Therapeutic Delivery · doi:10.4155/tde.15.71 · Cited by 9

Experimental evidences on the role of silica nanoparticles surface morphology on the loading, release and activity of three proteins

Zampini, G., Matino, D., Quaglia, G., Tarpani, L., Gargaro, M., Cecchetti, F., Iorio, A., Fallarino, F., & Latterini, L. (2019) · Microporous and Mesoporous Materials · doi:10.1016/j.micromeso.2019.06.005 · Cited by 11

Attenuating the immunogenicity of PEGylated liposomes by gangliosides

Park, K. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.03.002 · Cited by 9

Asymmetric Triblock Copolymer Nanocarriers for Controlled Localization and pH-Sensitive Release of Proteins

Vasquez‐Muñoz, D., Einfalt, T., Meier, W. P., & Palivan, C. G. (2016) · Langmuir · doi:10.1021/acs.langmuir.6b01803 · Cited by 8

Development of papain containing pellets produced by extrusion–spheronization: an operational stage approach

Varca, G. H. C., Lopes, P. S., & Ferraz, H. G. (2014) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2013.877481 · Cited by 8

A comparative analysis of catalytic activity and stability of microbial transglutaminase in controlled denaturing conditions

Caporale, A., Monti, A., Selis, F., Sandomenico, A., Tonon, G., Ruvo, M., & Doti, N. (2019) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2019.06.299 · Cited by 8

Evaluating Endosomal Escape of Caspase-3-Containing Nanomaterials Using Split GFP

Anson, F., Liu, B., Kanjilal, P., Wu, P., Hardy, J. A., & Thayumanavan, S. (2021) · Biomacromolecules · doi:10.1021/acs.biomac.0c01767 · Cited by 9

Allometry of Factor VIII and Informed Scaling of Next-Generation Therapeutic Proteins

Kosloski, M. P., Pisal, D. S., Mager, D. E., & Balu‐Iyer, S. V. (2013) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.23566 · Cited by 8

In vitro and in vivo biocompatibility evaluation of a novobiocin stimulus-responsive poly(ethylene glycol)-based hydrogel designed for soft tissue regeneration

Laird, D. F., El‐Baba, M. D., Hamri, G. C., Eberwein, P., Nelson, K., Tomakidi, P., & Steinberg, T. (2015) · Journal of Bioactive and Compatible Polymers · doi:10.1177/0883911515570370 · Cited by 8

Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-β for Cancer Gene Therapy

Hamana, A., Takahashi, Y., Nishikawa, M., & Takakura, Y. (2016) · Human Gene Therapy · doi:10.1089/hum.2016.023 · Cited by 7

Effect of IFN‑γ encapsulated liposomes on major signal transduction pathways in the lymphocytes of patients with lung cancer

Alhawamdeh, M., Almajali, B., Hourani, W., Al‐Jamal, H. A. N., Al-wajeeh, A. S., Mwafi, N., Al‐Hajaya, Y., Saad, H. K. M., Anderson, D. C., Odeh, M., et al. (2023) · Oncology Letters · doi:10.3892/ol.2023.14141 · Cited by 8

An effective cell-penetrating peptide-based loading method to extracellular vesicles and enhancement in cellular delivery of drugs

Zhang, J., Su, N., Liu, W., Li, M., Zheng, H., Li, B., Jin, X., Gao, M., & Zhang, X. (2025) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-025-05742-1 · Cited by 7

Highly variable aggregation and glycosylation profiles and their roles in immunogenicity to protein-based therapeutics

Sarsarshahi, S., Bhattacharya, S., Zacharias, Z. R., Kamel, E. S., Houtman, J. C. D., & Nejadnik, M. R. (2025) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2025.103771 · Cited by 7

Cationic nanogels as Trojan carriers for disruption of endosomes

Maximova, E. D., Zhiryakova, M. V., Файзулоев, Е. Б., Nikonova, A. A., Ezhov, A. A., Izumrudov, V. A., Orlov, V. N., Grozdova, I. D., & Melik‐Nubarov, N. S. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.10.051 · Cited by 7

Glycosaminoglycan-Conjugated Insulin Derivatives Suitable for Once-Daily Formulations

Fukushima, M., Hirayama, T., Ichikawa, M., Kitazawa, I., Kojima, K., Sakai, T., Takatsu, Y., & Ohtaki, T. (2019) · ACS Omega · doi:10.1021/acsomega.9b00059 · Cited by 7

Polyethylene-glycol-modified zwitterionic polymer assisted protein aggregation arrest and refolding

Debas, A., Matsumura, K., & Rajan, R. (2022) · Molecular Systems Design & Engineering · doi:10.1039/d2me00084a · Cited by 6

Functional characterization of recombinant human granulocyte colony stimulating factor (hGMCSF) immobilized onto silica nanoparticles

Selvarajan, V., Goswami, U., Chaubey, N., Ghosh, S. S., & Sanpui, P. (2015) · Biotechnology Letters · doi:10.1007/s10529-015-1984-0 · Cited by 6

Recombinant and chemo-/bio-orthogonal synthesis of liposomal thrombomodulin and its antithrombotic activity

Wang, L., Jiang, R., Liu, Y., Cheng, M., Wu, Q., & Sun, X. (2017) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2017.05.008 · Cited by 6

Design Rules for Antibody Delivery by Self-Assembled Block-Copolyelectrolyte Nanocapsules

Nikkhah, S. J., Cazade, P., McManus, J. J., & Thompson, D. (2022) · Macromolecules · doi:10.1021/acs.macromol.2c00118 · Cited by 6

Nanosized Delivery Systems for Therapeutic Proteins: Clinically Validated Technologies and Advanced Development Strategies

Moncalvo, F., Espinoza, M. I. M., & Cellesi, F. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00089 · Cited by 106

Engineered therapeutic proteins for sustained-release drug delivery systems

Nguyen, T. T. K., Pham, K., & Yook, S. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.09.018 · Cited by 55

Therapeutic Protein Delivery Systems

Niazi, S. K. (2022) · CRC Press eBooks · doi:10.1201/9781003146933-10

Nanotechnological Strategies for Protein Delivery

Villegas, M. R., Baeza, A., & Vallet‐Regí, M. (2018) · Molecules · doi:10.3390/molecules23051008 · Cited by 63

Recent Developments in Protein and Peptide Parenteral Delivery Approaches

Patel, A., Cholkar, K., & Mitra, A. K. (2014) · Therapeutic Delivery · doi:10.4155/tde.14.5 · Cited by 166