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Cited by 461

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Water proton MR properties of human blood at 1.5 Tesla: Magnetic susceptibility,T1,T2,T, and non‐Lorentzian signal behavior

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Spees, William M., Yablonskiy, Dmitriy A., Oswood, Mark C., Ackerman, Joseph J.H.·2001·Magnetic Resonance in Medicine
DOI 10.1002/mrm.1072
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Abstract

Accurate knowledge of the magnetic properties of human blood is required for the precise modeling of functional and vascular flow‐related MRI. Herein are reported determinations of the relaxation parameters of blood, employing in vitro samples that are well representative of human blood in situ. The envelope of the blood 1 H 2 O free‐induction decay signal magnitude during the first 100 msec following a spin echo at time TE is well‐ described empirically by an expression of the form,S(t) =So· exp{–R· (t– TE) –AR* · (t– TE)2}. The relaxation parameters AR* and Rincrease as a function of the square of the susceptibility difference between red blood cell and plasma and depend on the spin‐echo time. The Gaussian component,AR*, should be recognized in accurate modeling of MRI phenomena that depend upon the magnetic state of blood. The magnetic susceptibility difference between fully deoxygenated and fully oxygenated red blood cells at 37°C is 0.27 ppm, as determined independently by MR and superconducting quantum interference device (SQUID) measurements. This value agrees well with the 1936 report of Pauling and Coryell (Proc Natl Acad Sci USA 1936;22:210–216), but is substantially larger than that frequently used in MRI literature. Magn Reson Med 45:533–542, 2001. © 2001 Wiley‐Liss, Inc.

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Metadata

Authors
Spees, W. M., Yablonskiy, D. A., Oswood, M. C., & Ackerman, J. J. H.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
2001-03-27
Volume
45
Issue
4
Pages
533-542
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
DOI
10.1002/mrm.1072
OpenAlex
W2060182774
Cited by
461
References
37
FWCI
7.01
Type
journal article
Language
en
Open access
bronze

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