The DOI matches its Crossref record; 99 of the 103 references it cites were found in a registry or an index.
The Basal Ganglia and Chunking of Action Repertoires
Abstract
The basal ganglia have been shown to contribute to habit and stimulus-response (S-R) learning. These forms of learning have the property of slow acquisition and, in humans, can occur without conscious awareness. This paper proposes that one aspect of basal ganglia-based learning is the recoding of cortically derived information within the striatum. Modular corticostriatal projection patterns, demonstrated experimentally, are viewed as producing recoded templates suitable for the gradual selection of new input-output relations in cortico-basal ganglia loops. Recordings from striatal projection neurons and interneurons show that activity patterns in the striatum are modified gradually during the course of S-R learning. It is proposed that this recoding within the striatum can chunk the representations of motor and cognitive action sequences so that they can be implemented as performance units. This scheme generalizes Miller's notion of information chunking to action control. The formation and the efficient implementation of action chunks are viewed as being based on predictive signals. It is suggested that information chunking provides a mechanism for the acquisition and the expression of action repertoires that, without such information compression would be biologically unwieldy or difficult to implement. The learning and memory functions of the basal ganglia are thus seen as core features of the basal ganglia's influence on motor and cognitive pattern generators.
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“It has been suggested that the basal ganglia are important for chunking action sequences (Graybiel, 1998).”
From The Neural Correlates of Motor Skill Automaticity (2005) · cites this paper as Graybiel, 1998
In the citing paper
“Thus, decreased activity in the basal ganglia may reflect a more effective (chunked) representation that accompanies automatization.”
From The Neural Correlates of Motor Skill Automaticity (2005) · cites this paper as Graybiel, 1998
In the citing paper
“This learning process appears to be mediated, in part, by the dorsolateral striatum (or the putamen) (Knowlton et al., 1996; White, 1997; Graybiel, 1998; Hikosaka, 1998; Yin and Knowlton, 2006).”
From Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex (2007) · cites this paper as Graybiel, 1998
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Covert spatial selection in primate basal ganglia
Arcizet, F., & Krauzlis, R. J. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2005930 · Cited by 23
“Another well documented contribution of the basal ganglia in the primate is the coordination of motor outputs by grouping individual movements into action “chunks” (Graybiel 1998) during sequences of eye movements (Seo et al. 2012) or arm movements (Miyachi et al. 2002).”
BackgroundRodent models of serial reaction time tasks and their implementation in neurobiological research
Schwarting, R. K. W. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.07.004 · Cited by 23
Rabin, E., Muratori, L. M., Svokos, K. A., & Gordon, A. M. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.12.051 · Cited by 22
Phenomenology of abnormal movements in stuttering
Riva‐Posse, P., Busto-Marolt, L., Schteinschnaider, Á., Martinez-Echenique, L., Cammarota, Á., & Merello, M. (2008) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2007.11.006 · Cited by 22
Shephard, E., Groom, M. J., & Jackson, G. M. (2018) · Journal of Neuropsychology · doi:10.1111/jnp.12167 · Cited by 25
“Marsh et al. (2004) explained this impairment in terms of an inability to concatenate or chunk individual actions into a complete habitual behaviour, a mechanism believed to be critical in habit-learning and dependent on changes in striatal dopaminergic firing (described by Graybiel, 1998).”
BackgroundRole and Reference Grammar as a Framework for Linguistic Analysis
Valin, R. D. V. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199544004.013.0028 · Cited by 22
Olsen, C. M., Huang, Y., Goodwin, S. B., Ciobanu, D. C., Lu, L., Sutter, T. R., & Winder, D. G. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00224.2006 · Cited by 22
“The dStr is known to be involved in habit learning (38, 79), and drug-induced plasticity in the dStr has been proposed to underlie the compulsive nature of addiction (25, 34).”
BackgroundMuralidharan, V., Balasubramani, P. P., Chakravarthy, V. S., Gilat, M., Lewis, S. J. G., & Moustafa, A. A. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00649 · Cited by 21
“The cortico-basal ganglia system is organized as parallel loops associated with specific functional domains (Alexander et al., 1986; Parent and Hazrati, 1995; Graybiel, 1998).”
Using an unbiased symbolic movement representation to characterize Parkinson’s disease states
Abrami, A., Heisig, S., Ramos, V. F. M. L., Thomas, K. C., Ho, B. K., & Caggiano, V. (2020) · Scientific Reports · doi:10.1038/s41598-020-64181-3 · Cited by 20
“Purposeful and meaningful behaviors are built on sequences of movements 23 which are organized within the basal ganglia 29,40 , and transmitted through the brainstem 41–43 to the spinal cord, where movement signals are converted into synergistic muscle contractions 30 .”
BackgroundMcLaughlin, A. E., Diehl, G. W., & Redish, A. D. (2020) · International review of neurobiology · doi:10.1016/bs.irn.2020.11.009 · Cited by 25
“…decision-making relies on recognizing and categorizing situations based on experience and responding with appropriate, well-learned action-chains (Barnes, Kubota, Hu, Jin, & Graybiel, 2005; Dezfouli & Balleine, 2012; Graybiel, 1998; Mishkin & Appenzeller, 1987) (see Redish, 2013, for review).”
BackgroundInfluentialThunderstruck: The ACDC model of flexible sequences and rhythms in recurrent neural circuits
Calderon, C. B., Verguts, T., & Frank, M. J. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009854 · Cited by 21
“While several neural network models of corticostriatal circuit exist, these are typically applied to single shot stimulus-action pairings rather than sequential choices, despite extensive evidence that basal ganglia is implicated in such sequential behaviors (Graybiel, 1998).”
BackgroundSubthalamic and nigral neurons are differentially modulated during parkinsonian gait
Gulberti, A., Wagner, J., Horn, M. A., Reuss, J. H., Heise, M., Koeppen, J. A., Pinnschmidt, H. O., Westphal, M., Engel, A. K., Gerloff, C. P., et al. (2023) · Brain · doi:10.1093/brain/awad006 · Cited by 21
“Another hypothesis of the subthalamic function during gait could be derived from the BG model of motor sequencing of ‘chunks’ of motor-cognitive performance units.(60) Locomotion represents a sequence of alternating leg movements, which is disturbed in Parkinson’s disease with initial normal-sized, larger steps but in…”
BackgroundMethodTowards Learning of Generic Skills for Robotic Manipulation
Metzen, J. H., Fabisch, A., Senger, L., Fernández, J. D. G., & Kirchner, E. A. (2013) · Künstliche Intell. · doi:10.1007/s13218-013-0280-1 · Cited by 21
Temporal characteristics of overt attentional behavior during category learning
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Sequential motor skill in preadolescent children: The development of automaticity
Ruitenberg, M. F. L., Abrahamse, E. L., & Verwey, W. B. (2013) · Journal of Experimental Child Psychology · doi:10.1016/j.jecp.2013.04.005 · Cited by 23
Hypoxia-induced mitochondrial and nuclear DNA damage in the rat brain
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Phenomenological coping skills and the striatal memory system
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““Chunks take their advantage from being manipulable as entities, and the intervention of consciousness or attention might actually disrupt their smooth implementation” ( Graybiel 1998, 131).”
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“Nevertheless, models which propose the involvement of DAergic basal ganglia processes in sequential behavior are widely accepted ( Graybiel 1998; Doyon and Ungerleider 2002; Doyon et al. 2002; Da Cunha et al. 2009; Schwarting 2009).”
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“First, it is widely reported that aged animals with hippocampal-dependent spatial memory impairments tend to overuse of responsebased strategies (Barnes et al., 1980; Tomas Pereira et al., 2015) that are supported by the DS (Packard and McGaugh, 1992; Graybiel, 1998; Pych et al., 2005).”
BackgroundBhaduri, B., Abhilash, P. L., & Alladi, P. A. (2018) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2018.04.005 · Cited by 19
“The striatum is a major integrative component of the basal ganglia, in control of motor activities and reward behaviours (Graybiel, 1998; Parent and Hazrati, 1995; Schultz, 2002).”
Crittenden, J. R., Zhai, S., Sauvage, M., Kitsukawa, T., Burguière, E., Thomsen, M., Zhang, H., Costa, C., Martella, G., Ghiglieri, V., et al. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105473 · Cited by 19
“Psychomotor stimulants differentially affect immediate-early gene (IEG) expression in striosomes relative to their expression in the matrix, scored as a ratio (Crittenden and Graybiel, 2016; Graybiel, 1998, 2008; Saka et al., 2004).”
Reduced midbrain functional connectivity and recovery in abstinent heroin users
Xu, Y., Wang, S., Chen, L., Shao, Z., Zhang, M., Liu, S., Wen, X., Li, Y., Yang, W., Tang, F., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.10.011 · Cited by 18
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“Long-term changes in the synaptic strength of corticostriatal synapses are believed to represent the cellular substrate of sensorimotor learning (Di Filippo et al., 2009; Graybiel, 1998; Pisani et al., 2005).”
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“However, recent studies have shown that they are implicated in sensory, cognitive, and autonomic functions (Abbruzzese and Berardelli 2003; Graybiel 1998; Green et al. 2002a; Kimura 1995; Packard and Knowlton 2002; Schultz 1998; Soliveri et al. 1997).”
BackgroundAsudeh, A., & Toivonen, I. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199544004.013.0017 · Cited by 20
The Neural Plasticity of Giftedness
Kalbfleisch, M. L. (2009) · Springer eBooks · doi:10.1007/978-1-4020-6162-2_12 · Cited by 20
Glassman, R. B. (2000) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(99)00096-2 · Cited by 20
Activity density in the open field: a measure for differentiating the effect of psychostimulants
Kafkafi, N., & Elmer, G. I. (2004) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.11.004 · Cited by 20
Stein, D. J. (2006) · Annals of Clinical Psychiatry · doi:10.1080/10401230600801192 · Cited by 20
Chemical architecture of the basal ganglia
Graybiel, A. M., & Penney, J. B. (1999) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(99)80025-6 · Cited by 20
Li, H., & Jin, X. (2023) · eLife · doi:10.7554/elife.87644 · Cited by 22
Early-stage chunking of finger tapping sequences by persons who stutter and fluent speakers
Smits‐Bandstra, S., & Nil, L. F. D. (2012) · Clinical Linguistics & Phonetics · doi:10.3109/02699206.2012.746397 · Cited by 19
“These structures send organization signals critical to sequential movements whether they are eventually routed to hand or mouth execution areas of the motor cortex (Graybiel, 1998).”
BackgroundFunctional Anatomy: Dynamic States in Basal Ganglia Circuits
Garcia-Munoz, M., Carrillo‐Reid, L., & Arbuthnott, G. W. (2010) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2010.00144 · Cited by 18
“composItIonAl propertIes And bAsAl gAnglIA functIon Procedural memories and habits can be represented by basic motor actions (Graybiel, 1998; Grillner, 2006).”
BackgroundActivity of neurons in the caudate and putamen during a visuomotor task
Romero, M. C., Bermúdez, M. A., Vicente, A. F., Perez, R., & González, F. (2008) · Neuroreport · doi:10.1097/wnr.0b013e328307c3fc · Cited by 19
Chunking movements into sequence: The visual pre-selection of subsequent goals
Baldauf, D. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.01.041 · Cited by 19
“In fact, sequencing also requires the adjustment of spatiotemporal parameters of the individual components: the movements have to be chunked (Graybiel, 1998; Miller, 1956), i.e. combined into one common action plan, implying considerable crosstalk between the single movement units (Henry & Rogers,…”
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Ensemble encoding of action speed by striatal fast-spiking interneurons
Roberts, B. M., White, M. G., Patton, M. H., Chen, R., & Mathur, B. N. (2019) · Brain Structure and Function · doi:10.1007/s00429-019-01908-7 · Cited by 19
“Despite the critical role that FSIs play in action control, it remains unclear how FSI encoding of action compares to MSNs, which encode complex features of actions (Jin and Costa 2010; Graybiel 1998; Barnes et al.”
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Appetitive operant conditioning in mice: heritability and dissociability of training stages
Malkki, H. A. I. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00171 · Cited by 19
Abstract Rule Learning: The Differential Effects of Lesions in Frontal Cortex
Kayser, A. S., & D’Esposito, M. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs013 · Cited by 19
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Learning-induced changes in the neural circuits underlying motor sequence execution
Harpaz, N. K., Hardcastle, K., & Ölveczky, B. P. (2022) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2022.102624 · Cited by 17
A Perspective on Prosthetic Hands Control: From the Brain to the Hand
Gentile, C., & Gruppioni, E. (2023) · Prosthesis · doi:10.3390/prosthesis5040083 · Cited by 21
“These regions are responsible for modulating and refining hand movements, as well as for learning and habit formation [70,71].”
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Son, J., Kuhn, J., & Keefe, K. A. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.09.021 · Cited by 19
“The basis for the perseveration observed in individuals with a history of METH exposure is not yet clear; however, it has been suggested that corticostriatal circuitry is highly associated with perseveration (Graybiel, 1998, 2000; Haber and Calzavara, 2009).”
BackgroundRiegler, A. (2003) · Lecture notes in computer science · doi:10.1007/978-3-540-45002-3_2 · Cited by 18
“Such implicit knowledge is the result of a long and continuous training, or " habit learning " , as Ann Graybiel (1998) calls it.”
BackgroundRetention of Implicit Sequence Learning in Persons Who Stutter and Persons With Parkinson's Disease
Smits‐Bandstra, S., & Gracco, V. L. (2014) · Journal of Motor Behavior · doi:10.1080/00222895.2014.961890 · Cited by 18
“Facilitation of sequential movement patterns is thought to be regulated by the cortico-striato-thalamo-cortical circuit (Graybiel, 1998).”
BackgroundModelling the Stroop effect: A connectionist approach
Kaplan, G. B., Şengör, N. S., Gurvit, H. I., & Guzelis, C. (2006) · Neurocomputing · doi:10.1016/j.neucom.2006.05.009 · Cited by 18
“According to Graybiel automated behavior is an attribute of the BG and this explains the BG lesioned patient's difficulties in performing sequential actions [29].”
BackgroundObsessive-compulsive disorders and dermatologic disease.
Vythilingum, B., & Stein, D. J. (2005) · Dermatologia clinica · doi:10.1016/j.det.2005.05.006 · Cited by 17
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Jackendoff, R. S. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199544004.013.0023 · Cited by 18
The Proceduralization of Hominin Knapping Skill: Memorizing Different Lithic Technologies
Muller, A., Shipton, C., & Clarkson, C. (2023) · Cambridge Archaeological Journal · doi:10.1017/s0959774323000070 · Cited by 20
“Chunking has been hypothesized to assist the memorization of long procedural sequences by dividing them into smaller and easier to memorize ‘chunks’, relieving the strain on both short-term and long-term memory (Ericsson & Kintsch 1995; Graybiel 1998; Sakai et al. 2003; Thalmann et al. 2019).”
BackgroundThe Hippocampus Preorders Movements for Skilled Action Sequences
Yewbrey, R., & Kornysheva, K. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0832-24.2024 · Cited by 21
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“…information is transformed where representations of motor and cognitive action sequences can be integrated into more complex behavioral responses (Graybiel, 1998) emphasizing that in addition to the role of striatum in motor control, the striatum plays an essential role in the function of more…”
BackgroundFunctional neurochemistry of the basal ganglia
Samadi, P., Rouillard, C., Bédard, P. J., & Paolo, T. D. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)83002-8 · Cited by 17
“Some of the changes occurring during learning involve altering the parameters of corticostriatal transmission (Graybiel, 1998).”
BackgroundDorsal hippocampal lesions boost performance in the rat sequential reaction time task
Eckart, M. T., Huelse-Matia, M. C., & Schwarting, R. K. W. (2011) · Hippocampus · doi:10.1002/hipo.20965 · Cited by 17
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“…of our interest in potentially separable procurement and consumption behaviors, results of procedures deliberately designed to study unitized or ‘‘chunked” strings of responses (e.g., Greybiel, 1998; Ostlund, Winterbauer, & Balleine, 2009) will not be discussed in detail in the present review.”
The BesMan Learning Platform for Automated Robot Skill Learning
Gutzeit, L., Fabisch, A., Otto, M., Metzen, J. H., Hansen, J. M., Kirchner, F., & Kirchner, E. A. (2018) · Frontiers in Robotics and AI · doi:10.3389/frobt.2018.00043 · Cited by 18
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BackgroundMethodInfluentialInteractive reservoir computing for chunking information streams
Asabuki, T., Hiratani, N., & Fukai, T. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006400 · Cited by 17
Hamano, Y. H., Sugawara, S. K., Yoshimoto, T., & Sadato, N. (2019) · Neuroscience Research · doi:10.1016/j.neures.2019.03.004 · Cited by 17
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Striatal Neuropeptides Enhance Selection and Rejection of Sequential Actions
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“Patterned SP connectivity may allow the striatum to incorporate probabilistic links between component actions that could represent a neurological basis for “chunking” (Graybiel, 1998) and higher– order hierarchical groups (Balleine et al., 2015).”
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Segment difficulty in two-stroke movements in patients with Parkinson’s disease
Rand, M. K., Gemmert, A. W. A. V., & Stelmach, G. E. (2002) · Experimental Brain Research · doi:10.1007/s00221-002-1000-5 · Cited by 17
“Recent unitary studies and inactivation experiments in animals also implicate an involvement of basal ganglia in organizing sequential actions ( Graybiel 1998; Kermadi and Joseph 1995; Matsumoto et al. 1999; Miyachi et al. 1997; Mushiake and Strick 1995).”
Cerebral reorganization in Parkinson's disease.
Helmich, R. C. G. (2011) · Radboud Repository (Radboud University) · Cited by 17
Sweis, B. M., Thomas, M. J., & Redish, A. D. (2018) · Learning & Memory · doi:10.1101/lm.047795.118 · Cited by 17
Regional Interplay for Temporal Processing in Parkinson’s Disease: Possibilities and Challenges
Schwartze, M., & Kotz, S. A. (2016) · Frontiers in Neurology · doi:10.3389/fneur.2015.00270 · Cited by 16
“One of the most fundamental functions attributed to the basal ganglia and associated brain regions is the patterning and chunking of behavior from simple motion sequences to complex cognitive sequences (6, 7).”
BackgroundA novel free-operant framework enables experimental habit induction in humans
Gera, R., Barak, S., & Schönberg, T. (2023) · Behavior Research Methods · doi:10.3758/s13428-023-02263-6 · Cited by 18
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“…in which the task is repeatedly accomplished, there is evidence that control may be transferred from cortical areas such as the prefrontal cortex (PFC) to the basal ganglia (BG) (Doyon and Benali, 2005; Packard and Knowlton, 2002; Jog et al., 1999; Puttemans et al., 2005; Graybiel, 1998).”
BackgroundJaremko, K. M., Thompson, N. L., Reyes, B. A. S., Jin, J., Ebersole, B., Jenney, C. B., Grigson, P. S., Levenson, R. G., Berrettini, W. H., & Bockstaele, E. J. V. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.12.003 · Cited by 16
Reversal Learning in Humans and Gerbils: Dynamic Control Network Facilitates Learning
Jarvers, C., Brosch, T., Brechmann, A., Woldeit, M. L., Schulz, A. L., Ohl, F. W., Lommerzheim, M., & Heiko Neumann, B. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00535 · Cited by 17
“These experts are then selectively activated by a gating network (Jacobs et al., 1991a,b; Graybiel, 1998) or in a hierarchically organized structure (Frank and Badre, 2012).”
BackgroundMethodInfluentialLearning performance is linked to procedural memory consolidation across both sleep and wakefulness
Rångtell, F. H., Karamchedu, S., Andersson, P. S. G., van Egmond, L. T., Hultgren, T., Broman, J., Cedernaes, J., & Benedict, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-09263-5 · Cited by 17
Sequential behavior in the rat: role of skill and attention
Domenger, D., & Schwarting, R. K. W. (2007) · Experimental Brain Research · doi:10.1007/s00221-007-0987-z · Cited by 16
“In a similar way, one could assume that the violation not only interfered with processing of a single position, but with a chunk of several positions, since chunking is also thought to be critical for sequential performance (e.g., Graybiel 1998).”
Senger, L., Schröer, M., Metzen, J. H., & Kirchner, E. A. (2014) · Proceedings - International Conference on Pattern Recognition/Proceedings/International Conference on Pattern Recognition · doi:10.1109/icpr.2014.781 · Cited by 16
“This process is called chunking of action repertoires [3].”
BackgroundSuperior Longitudinal Fasciculus and Arcuate Fasciculus
Schmahmann, J. D., & Pandya, D. Ν. (2006) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195104233.003.0013 · Cited by 19
Biological Psychiatry and Psychopharmacology
Fountoulakis, K. N., Nimatoudis, I., & Stahl, S. M. (2019) · Springer eBooks · doi:10.1007/978-3-030-18323-3_13 · Cited by 17
Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortexPreprint
Jamali, S., Bagur, S., Brémont, E., van Kerkoerle, T., Dehaene, S., & Bathellier, B. (2024) · eLife · doi:10.7554/elife.102702 · Cited by 16
Ideomotor learning: Time to generalize a longstanding principle
Moeller, B., & Pfister, R. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104782 · Cited by 15
Ji, J., Ye, C., & Yang, C. (2024) · Knowledge-Based Systems · doi:10.1016/j.knosys.2024.111450 · Cited by 15
Fan, Y., Wang, M., Fang, F., Ding, N., & Luo, H. (2024) · Nature Human Behaviour · doi:10.1038/s41562-024-02047-8 · Cited by 20
Intelligent Assistive System Using Real-Time Action Recognition for Stroke Survivors
Jean-Baptiste, E. M. D., Nabiei, R., Parekh, M., Fringi, E., Drozdowska, B. A., Baber, C., Jančovič, P., Rotshtein, P., & Russell, M. J. (2014) · IEEE International Conference on Healthcare Informatics (ICHI) · doi:10.1109/ichi.2014.13 · Cited by 15
“Indeed, in [23], [24] De Klein and Graybiel highlighted the impact of familiar and unfamiliar sequences on success rate.”
BackgroundThe Adaptive Approach to Grammar
Givón, T. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780199544004.013.0002 · Cited by 15
Cunningham, P. J., Regier, P. S., & Redish, A. D. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.3080-20.2021 · Cited by 16
“Other perspectives conceptualize procedural actions as action-chains that have been “chunked” together into a cohesive sequence that defines a single unit eligible for action selection (Graybiel, 1998; Barnes et al., 2005; Smith and Graybiel, 2013).”
BackgroundAsem, J. S. A., & Holland, P. C. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.06.009 · Cited by 15
“In particular, striatal projection neurons and interneurons show activity patterns that modify gradually during the slow acquisition of stimulus–response (S–R) learning, producing ‘‘action chunks’’ for future efficient performance (Graybiel, 1998).”
BackgroundSchönberger, A. R., Hagelweide, K., Pelzer, E. A., Fink, G. R., & Schubotz, R. I. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.09.017 · Cited by 16
“The striatal loops' contribution to cognitive sequencing can be understood in the framework put forward by Graybiel (1998), according to which the striatum chunks motor performance in order to allow implicit learning of sequences.”
Timing Matters? Learning of Complex Spatiotemporal Sequences in Left-hemisphere Stroke Patients
Dovern, A., Fink, G. R., Timpert, D. C., Saliger, J., Karbe, H., Weiss, P. H., & Koch, I. (2015) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00890 · Cited by 15
“One key structure known to be critical for the chunking process is the striatum (Penhune & Steele, 2012; Orban et al., 2011; Graybiel, 1998).”
BackgroundA review and empirical study of the composite scales of the Das–Naglieri cognitive assessment system
McCrea, S. M. (2009) · Psychology Research and Behavior Management · doi:10.2147/prbm.s5074 · Cited by 15
“93 However the data do suggest that in the posterior cortex (eg, anterior temporal regions) that verbal and nonverbal sequencing is Abbreviations: Sex: M, male; F, female; Ethnicity: A, Asian; B, Black; C, Caucasian; F, First Nations.”
Nakajima, T., Hosaka, R., Tsuda, I., Tanji, J., & Mushiake, H. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0855-13.2013 · Cited by 15
“These findings provide the basis for understanding mechanisms of impairments in sequential behavior among patients with lesions in the medial motor area (Gentilucci et al., 2000) or the basal ganglia with which the medial frontal cortex is closely linked (Marsden, 1984; Graybiel, 1998).”
BackgroundStriatal Network Models of Huntington's Disease Dysfunction Phenotypes
Zheng, P., & Kozloski, J. (2017) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2017.00070 · Cited by 15
“The neuronal structure affected most by HD, striatum, acts in global brain circuitry as the input stage to the Basal Ganglia (BG), a set of basal forebrain structures involved in behavioral reinforcement learning and action selection among all vertebrate organisms (Graybiel, 1998).”
BackgroundBonnavion, P., Fernández, E. P., Varin, C., & d’Exaerde, A. D. K. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.01.009 · Cited by 15
“…lines of evidences suggest that the motor circuit of the BG, and particularly the DS, play an important role in these motor planning and learning processes involving sequential behaviors (Graybiel, 1998; Yin and Knowlton, 2006; Balleine et al., 2009; Hilario et al., 2012; Jin and Costa, 2015).”
BackgroundInfluentialZhang, Z., Luo, Y., Wang, C., Warren, C. M., Qi, X., Xing, Q., Cao, B., Lei, Y., & Li, H. (2019) · Biological Psychology · doi:10.1016/j.biopsycho.2019.02.004 · Cited by 15
“…has wide application in human 72 cognition (Gobet et al., 2001), affecting a diverse set of mental tasks including the 73 learning of action repertoires (Graybiel, 1998) speech (Gilbert, Boucher, & Jemel, 74 2015), memory (Miller, 1956), and problem solving (Chase & Simon, 1973; De Groot, 75 1978).”
Stimulus and response chunking in the Hebb Digits task
O’Shea, G., & Clegg, B. A. (2005) · Psychological Research · doi:10.1007/s00426-004-0198-1 · Cited by 15
Neurodynamics of the Prefrontal Cortex during Conditional Visuomotor Associations
Loh, M., Pasupathy, A., Miller, E. K., & Deco, G. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2008.20031 · Cited by 15
“…that the basal ganglia have a dominant role in the learning of new associations (Pasupathy & Miller, 2005; Bar-Gad et al., 2003; Houk & Wise, 1995), whereas the other one suggests that they are responsible for consolidating associations, and thus, habits (Packard & Knowlton, 2002; Graybiel, 1998).”
BackgroundInfluentialPieruccini‐Faria, F., Jones, J. A., & Almeida, Q. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.019 · Cited by 14
“This would suggest that basal ganglia damage leads to a decreased ability to store complex movement plans (Benecke et al., 1986, 1987; Graybiel, 1998).”
Edelman, S. (2017) · Language Sciences · doi:10.1016/j.langsci.2017.04.003 · Cited by 14
An avian cortical circuit for chunking tutor song syllables into simple vocal-motor units
Mackevicius, E. L., Happ, M., & Fee, M. S. (2020) · Nature Communications · doi:10.1038/s41467-020-18732-x · Cited by 20
Caligiore, D., Tommasino, P., Sperati, V., & Baldassarre, G. (2014) · Adaptive Behavior · doi:10.1177/1059712314539710 · Cited by 15
“…of brain, in particular: (a) the organization of the motor cortex based on neural columns (Aflalo & Graziano, 2011); (b) the organization of basal ganglia in channels, where channels support trial-and-error learning and the selection of different actions (Graybiel, 1998; Gurney et al., 2001b).”
BackgroundOn the Asymptotic Equivalence Between Differential Hebbian and Temporal Difference Learning
Kolodziejski, C., Porr, B., & Wörgötter, F. (2008) · Neural Computation · doi:10.1162/neco.2008.04-08-750 · Cited by 14
“Their response, which is a reduction of activity, is exceedingly well timed and occurs together with conditioned stimuli (Graybiel, 1998; Morris, Arkadir, Nevet, Vaadia, & Bergman, 2004).”
BackgroundZapparoli, L., Tettamanti, M., Porta, M., Zerbi, A., Servello, D., Banfi, G., & Paulesu, E. (2017) · European Journal of Neuroscience · doi:10.1111/ejn.13658 · Cited by 14
Metadata
- Authors
- Graybiel, A. M.
- Affiliations
- Massachusetts Institute of Technology (US)
- Corresponding author
- Graybiel, Ann M.
- ORCID
- Graybiel, Ann M.
- Venue
- Neurobiology of Learning and Memory
- Publisher
- Elsevier BV
- Published
- 1998-07
- Volume
- 70
- Issue
- 1-2
- Pages
- 119-136
- ISSN
- 1074-7427 (ISSN-L)
- OpenAlex
- W2148201341
- Cited by
- 1,042
- References
- 103
- Citations by year
- 2026: 25 · 2025: 32 · 2024: 31 · 2023: 48 · 2022: 26 · 2021: 47 · 2020: 36 · 2019: 25 · 2018: 37 · 2017: 39 · 2016: 42 · 2015: 43 · 2014: 41 · 2013: 37 · 2012: 84
- FWCI
- 8.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurobiology of Learning and Memory (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (R03 MH57878, R01 NS25529)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- basal ganglia, striatum, repertoires of action, habit learning, stimulus-response learning, corticostriatal projections, striatal projection neurons, striatal interneurons, predictive signals
- MeSH terms
- Animals, Basal Ganglia, Brain Mapping, Corpus Striatum, Habits, Humans, Learning, Memory, Models, Neurological, Nerve Net, Synaptic Transmission, Neuronal Plasticity, Obsessive-Compulsive Disorder, Parkinson Disease, Neocortex, In Vitro Techniques
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