Cited by 317Multimodal Machine Learning ApplicationsArtificial Intelligence in Healthcare and EducationRadiomics and Machine Learning in Medical Imaging

Making the Most of Text Semantics to Improve Biomedical Vision-Language Processing

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Boecking, Benedikt, Usuyama, Naoto, Bannur, Shruthi, Castro, Daniel C., Schwaighofer, Anton, Hyland, Stephanie, Wetscherek, Maria, Naumann, Tristan +4 more·2022·Lecture Notes in Computer Science

Abstract

Multi-modal data abounds in biomedicine, such as radiology images and reports. Interpreting this data at scale is essential for improving clinical care and accelerating clinical research. Biomedical text with its complex semantics poses additional challenges in vision--language modelling compared to the general domain, and previous work has used insufficiently adapted models that lack domain-specific language understanding. In this paper, we show that principled textual semantic modelling can substantially improve contrastive learning in self-supervised vision--language processing. We release a language model that achieves state-of-the-art results in radiology natural language inference through its improved vocabulary and novel language pretraining objective leveraging semantics and discourse characteristics in radiology reports. Further, we propose a self-supervised joint vision--language approach with a focus on better text modelling. It establishes new state of the art results on a wide range of publicly available benchmarks, in part by leveraging our new domain-specific language model. We release a new dataset with locally-aligned phrase grounding annotations by radiologists to facilitate the study of complex semantic modelling in biomedical vision--language processing. A broad evaluation, including on this new dataset, shows that our contrastive learning approach, aided by textual-semantic modelling, outperforms prior methods in segmentation tasks, despite only using a global-alignment objective.

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  • The official MIMIC-CXR test split is highly enriched for abnormal cases, hence prior studies are more common.

    “We note that the official MIMIC-CXR test split is highly enriched for abnormal cases, 26 hence prior studies are more common (Table 1).”

    From MAIRA-2: Grounded Radiology Report Generation (2024) · cites this paper as [26]

    Section 4.1 (p. 9) describes the paper’s MIMIC-CXR training, validation, and held-out evaluation data, but does not give the abnormal-case distribution of the official test split. Section B.1 (p. 28) says normal scans are generally more common; it does not address whether the official test split is enriched for abnormal cases. Searches for the official split and abnormal-case prevalence did not establish the claim. (LLM, conf=0.74)

    Experimental — accuracy not yet measured
  • The paper's qualitative evaluation approach differs from most existing works that primarily ask experts to rate overall report quality via a Likert scale, provide total error counts/categorisation, or engage in comparison rankings.

    “By inviting a domain expert to review and adapt individual phrase outputs, our approach to qualitative evaluation of report generation differs from most existing works that primarily ask experts to rate overall report quality via a (Likert-) scale; 59 provide total error counts/ categorisation; 48,60 or engage in comparison rankings across different report candidates.61”

    From MAIRA-2: Grounded Radiology Report Generation (2024) · cites this paper as [48]

    Section C.1 (p. 30) describes radiologists reviewing phrase–bounding-box annotations for a grounding dataset, not evaluating generated reports. Section 4.1 (p. 10) describes grounding metrics. Searches for Likert ratings, report-error counts or categories, and candidate rankings found no passage supporting the attributed evaluation approach. (LLM, conf=0.77)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 22

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Authors
Boecking, B., Usuyama, N., Bannur, S., Castro, D. C., Schwaighofer, A., Hyland, S., Wetscherek, M., Naumann, T., Nori, A., Alvarez-Valle, J., Poon, H., & Oktay, O.
Affiliations
Microsoft (United States) (US)
Corresponding author
Oktay, Ozan
Venue
Lecture Notes in Computer Science
Published
2022
Pages
1-21
ISSN
  • 0302-9743 (ISSN-L)
  • 1611-3349
OpenAlex
W4312533035
Cited by
317
References
68
Citations by year
2026: 88 · 2025: 122 · 2024: 73 · 2023: 34
FWCI
20.76
Type
conference paper
Language
en
Open access
Locations
  • Lecture notes in computer science (publishedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Topics
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
Keywords
radiology reports, contrastive learning, domain-specific language models, natural language inference, phrase grounding, multimodal medical data

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