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The Cardiovascular Effects of Methylxanthines
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“Caffeine, although tendentially promoting increases in cholesterol levels [102], seems to prevent cholesterol crystallization by possibly inhibiting gallbladder absorption [96,103,104].”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [102]
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Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01396-6 · Cited by 2,624
Effects of Caffeine on Plasma Renin Activity, Catecholamines and Blood Pressure
Robertson, D., Frölich, J. C., Carr, R. K., Watson, J. T., Hollifield, J. W., Shand, D. G., & Oates, J. A. (1978) · New England Journal of Medicine · doi:10.1056/nejm197801262980403 · Cited by 757
Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review
van Dam, R. M., & Hu, F. B. (2005) · JAMA · doi:10.1001/jama.294.1.97 · Cited by 662
Tolerance to the humoral and hemodynamic effects of caffeine in man.
Robertson, D., Wade, D., Workman, R., Woosley, R. L., & Oates, J. A. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110124 · Cited by 501
Coffee, CYP1A2 genotype, and risk of myocardial infarction
Cornelis, M. C., El-Sohemy, A., Kabagambe, E. K., & Campos, H. (2006) · JAMA · doi:10.1001/jama.295.10.1135 · Cited by 490
Are Methylxanthine Effects Due to Antagonism of Endogenous Adenosine?
Fredholm, B. B. (1979) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(79)90046-4 · Cited by 409
Noordzij, M., Uiterwaal, C. S., Arends, L. R., Kok, F. J., Grobbee, D. E., & Geleijnse, J. M. (2005) · Journal of Hypertension · doi:10.1097/01.hjh.0000166828.94699.1d · Cited by 376
Coffee, caffeine and blood pressure: a critical review
Nurminen, M.-L., Niittynen, L., Korpela, R., & Vapaatalo, H. (1999) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600899 · Cited by 351
Jee, S. H., He, J., Whelton, P. K., Suh, I., & Klag, M. J. (1999) · Hypertension · doi:10.1161/01.hyp.33.2.647 · Cited by 276
Olthof, M. R., Hollman, P. C., Zock, P. L., & Katan, M. B. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.3.532 · Cited by 222
Research works printed but not linked: 135
- Agwunobi J, Abedin M, Young M, Beeram M, Sinkford S (1996) Impact of theophylline use in Wolff-Parkinson-White syndrome. J Natl Med Assoc 88:450–452
- Andreas S, Reiter H, Luthje L et al (2004) Differential effects of theophylline on sympathetic excitation, hemodynamics, and breathing in congestive heart failure. Circulation 110:2157–2162 · DOI
- Bak AA, Grobbee DE (1990) A randomized study on coffee and blood pressure. J Hum Hypertens 4:259–264
- Bardou M, Goirand F, Bernard A et al (2002) Relaxant effects of selective phosphodiesterase inhibitors on U46619 precontracted human intralobar pulmonary arteries and role of potassium channels. J Cardiovasc Pharmacol 40:153–161 · DOI
- Barraco RA, Clough-Helfman C, Goodwin BP, Anderson GF (1995) Evidence for presynaptic adenosine A2A receptors associated with norepinephrine release and their desensitization in the rat nucleus tractus solitarius. J Neurochem 65:1604–1611 · DOI
- Baylin A, Hernandez-Diaz S, Kabagambe EK, Siles X, Campos H (2006) Transient exposure to coffee as a trigger of a first nonfatal myocardial infarction. Epidemiology 17:506–511 · DOI · Paper page
- Belardinelli L, Linden J, Berne RM (1989) The cardiac effects of adenosine. Prog Cardiovasc Dis 32:73–97 · DOI
- Belardinelli L, Shryock JC, Snowdy S et al (1998) The A2A adenosine receptor mediates coronary vasodilation. J Pharmacol Exp Ther 284:1066–1073 · DOI
- Belardinelli L, Shryock JC, Song Y, Wang D, Srinivas M (1995) Ionic basis of the electrophysiological actions of adenosine on cardiomyocytes. FASEB J 9:359–365 · DOI
- Biaggioni I, Olafsson B, Robertson RM, Hollister AS, Robertson D (1987) Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation. Circ Res 61:779–786 · DOI
- Biaggioni I, Onrot J, Hollister AS, Robertson D (1986) Cardiovascular effects of adenosine infusion in man and their modulation by dipyridamole. Life Sci 39:2229–2236 · DOI
- Biaggioni I, Paul S, Puckett A, Arzubiaga C (1991) Caffeine and theophylline as adenosine receptor antagonists in humans. J Pharmacol Exp Ther 258:588–593 · DOI
- Bijlstra P, van Ginneken EE, Huls M, van Dijk R, Smits P, Rongen GA (2004) Glyburide inhibits dipyridamole-induced forearm vasodilation but not adenosine-induced forearm vasodilation. Clin Pharmacol Ther 75:147–156 · DOI
- Brodmann M, Lischnig U, Lueger A, Pilger E, Stark G (2003) The effect of caffeine on peripheral vascular resistance in isolated perfused guinea pig hind limbs. J Cardiovasc Pharmacol 42:506–510 · DOI
- Brown NJ, Ryder D, Nadeau J (1993) Caffeine attenuates the renal vascular response to angiotensin II infusion. Hypertension 22:847–852 · DOI
- Burr ML, Gallacher JE, Butland BK, Bolton CH, Downs LG (1989) Coffee, blood pressure and plasma lipids: a randomized controlled trial. Eur J Clin Nutr 43:477–483
- Butcher RW, Sutherland EW (1962) Adenosine 3′,5′-phosphate in biological materials. I. Purification and properties of cyclic 3′,5′-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3′,5′-phosphate in human urine. J Biol Chem 237:1244–1250 · DOI · Paper page
- Carr CS, Hill RJ, Masamune H et al (1997) Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia. Cardiovasc Res 36:52–59 · DOI
- Casiglia E, Bongiovi S, Paleari CD et al (1991) Haemodynamic effects of coffee and caffeine in normal volunteers: a placebo-controlled clinical study. J Intern Med 229:501–504 · DOI
- Cawley MJ, Al-Jazairi AS, Stone EA (2001) Intravenous theophylline–an alternative to temporary pacing in the management of bradycardia secondary to AV nodal block. Ann Pharmacother 35:303–307 · DOI
- Christensen B, Mosdol A, Retterstol L, Landaas S, Thelle DS (2001) Abstention from filtered coffee reduces the concentrations of plasma homocysteine and serum cholesterol: a randomized controlled trial. Am J Clin Nutr 74:302–307 · DOI
- Costa F, Biaggioni I (1994) Role of adenosine in the sympathetic activation produced by isometric exercise in humans. J Clin Invest 93:1654–1660 · DOI
- Cox DA, Vita JA, Treasure CB, Fish RD, Selwyn AP, Ganz P (1989) Reflex increase in blood pressure during the intracoronary administration of adenosine in man. J Clin Invest 84:592–596 · DOI
- DeLago A, El-Hajjar M, Kirnus M (2008) Aminophylline for prevention of bradyarrhythmias induced by rheolytic thrombectomy. J Invasive Cardiol 20:9A–11A
- Dimarco AF, Nochomovitz M, DiMarco MS, Altose MD, Kelsen SG (1985) Comparative effects of aminophylline on diaphragm and cardiac contractility. Am Rev Respir Dis 132:800–805
- Donoso MV, Aedo F, Huidobro-Toro JP (2006) The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals. J Neurochem 96:1680–1695 · DOI
- Edlund A, Conradsson T, Sollevi A (1995) A role for adenosine in coronary vasoregulation in man. Effects of theophylline and enprofylline. Clin Physiol 15:623–636 · DOI
- Edlund A, Sollevi A (1995) Theophylline increases coronary vascular tone in humans: evidence for a role of endogenous adenosine in flow regulation. Acta Physiol Scand 155:303–311 · DOI
- Eppel GA, Ventura S, Evans RG (2006) Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids. Br J Pharmacol 149:523–531 · DOI
- Farag NH, Vincent AS, McKey BS, Whitsett TL, Lovallo WR (2005) Hemodynamic mechanisms underlying the incomplete tolerance to caffeine′s pressor effects. Am J Cardiol 95: 1389–1392 · DOI · Paper page
- Feoktistov I, Biaggioni I (1995) Adenosine A2B receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96:1979–1986 · DOI
- Francis SH, Sekhar KR, Ke H, Corbin JD (2010) Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
- Fredholm BB (1984) Cardiovascular and renal actions of methylxanthines. Prog Clin Biol Res 158:303–330
- Fredholm BB, Hedqvist P, Vernet L (1978) Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5′-nucleotidase and adenosine deaminase. Biochem Pharmacol 27:2845–2850 · DOI
- Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J (2001a) International union of pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527–552 · DOI · Paper page
- Fredholm BB, Irenius E, Kull B, Schulte G (2001b) Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells. Biochem Pharmacol 61:443–448 · DOI · Paper page
- Fredholm BB, Persson CG (1982) Xanthine derivatives as adenosine receptor antagonists. Eur J Pharmacol 81:673–676 · DOI
- Frost L, Vestergaard P (2005) Caffeine and risk of atrial fibrillation or flutter: the Danish diet, cancer, and health study. Am J Clin Nutr 81:578–582 · DOI
- Grossmann M, Braune J, Ebert U, Kirch W (1998) Dilatory effects of phosphodiesterase inhibitors on human hand veins in vivo. Eur J Clin Pharmacol 54:35–39 · DOI
- Grubben MJ, Boers GH, Blom HJ et al (2000) Unfiltered coffee increases plasma homocysteine concentrations in healthy volunteers: a randomized trial. Am J Clin Nutr 71:480–484 · DOI
- Guerreiro S, Marien M, Michel PP (2010) Methylxanthines and ryanodine receptor channels. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
- Happonen P, Voutilainen S, Tuomainen TP, Salonen JT (2006) Catechol-O-methyltransferase gene polymorphism modifies the effect of coffee intake on incidence of acute coronary events. PLoS ONE 1:e117 · DOI
- Harada K, Ohashi K, Kumagai Y, Fujimura A (1995) Comparison of venodilatory effect of amrinone and theophylline in human subjects. J Clin Pharmacol 35:1067–1070 · DOI
- Hasko G, Linden J, Cronstein B, Pacher P (2008) Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7:759–770 · DOI
- Hausenloy DJ, Yellon DM (2007) Preconditioning and postconditioning: united at reperfusion. Pharmacol Ther 116:173–191 · DOI · Paper page
- Hinschen AK, Rose'Meyer RB, Headrick JP (2003) Adenosine receptor subtypes mediating coronary vasodilation in rat hearts. J Cardiovasc Pharmacol 41:73–80 · DOI
- Hu G, Jousilahti P, Nissinen A, Bidel S, Antikainen R, Tuomilehto J (2007) Coffee consumption and the incidence of antihypertensive drug treatment in Finnish men and women. Am J Clin Nutr 86:457–464 · DOI
- Ishibashi Y, Duncker DJ, Zhang J, Bache RJ (1998) ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise. Circ Res 82:346–359 · DOI
- Ishida S, Ito M, Takahashi N, Fujino T, Akimitsu T, Saikawa T (1996) Caffeine induces ventricular tachyarrhythmias possibly due to triggered activity in rabbits in vivo. Jpn Circ J 60:157–165 · DOI
- Jansen DF, Nedeljkovic S, Feskens EJ et al (1995) Coffee consumption, alcohol use, and cigarette smoking as determinants of serum total and HDL cholesterol in two Serbian cohorts of the Seven Countries Study. Arterioscler Thromb Vasc Biol 15:1793–1797 · DOI
- Jee SH, He J, Appel LJ, Whelton PK, Suh I, Klag MJ (2001) Coffee consumption and serum lipids: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol 153:353–362 · DOI · Paper page
- Kabagambe EK, Baylin A, Campos H (2007) Nonfatal acute myocardial infarction in Costa Rica: modifiable risk factors, population-attributable risks, and adherence to dietary guidelines. Circulation 115:1075–1081 · DOI
- Kamphuis J, Smits P, Thien T (1994) Vascular effects of pentoxifylline in humans. J Cardiovasc Pharmacol 24:648–654 · DOI
- Kemp BK, Cocks TM (1999) Adenosine mediates relaxation of human small resistance-like coronary arteries via A2B receptors. Br J Pharmacol 126:1796–1800 · DOI
- Klag MJ, Wang NY, Meoni LA et al (2002) Coffee intake and risk of hypertension: the Johns Hopkins precursors study. Arch Intern Med 162:657–662 · DOI · Paper page
- Klatsky AL, Koplik S, Kipp H, Friedman GD (2008) The confounded relation of coffee drinking to coronary artery disease. Am J Cardiol 101:825–827 · DOI
- Klotz KN, Hessling J, Hegler J et al (1998) Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 357:1–9 · DOI
- Kong H, Jones PP, Koop A, Zhang L, Duff HJ, Chen SR (2008) Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor. Biochem J 414:441–452 · DOI
- Lai EY, Patzak A, Steege A et al (2006) Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction. Kidney Int 70:690–698 · DOI
- Lieu HD, Shryock JC, von Mering GO et al (2007) Regadenoson, a selective A2A adenosine receptor agonist, causes dose-dependent increases in coronary blood flow velocity in humans. J Nucl Cardiol 14:514–520 · DOI
- Lindahl B, Johansson I, Huhtasaari F, Hallmans G, Asplund K (1991) Coffee drinking and blood cholesterol: effects of brewing method, food intake and life style. J Intern Med 230:299–305 · DOI
- Little JA, Shanoff HM, Csima A, Toronto MA, Yano R (1966) Coffee and serum-lipids in coronary heart-disease. Lancet 1:732–734 · DOI
- Lo YC, Tsou HH, Lin RJ et al (2005) Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition. Life Sci 76:931–944 · DOI
- Lopez-Garcia E, van Dam RM, Li TY, Rodriguez-Artalejo F, Hu FB (2008) The relationship of coffee consumption with mortality. Ann Intern Med 148:904–914 · DOI
- McNamara R, Maginn M, Harkin A (2007) Caffeine induces a profound and persistent tachycardia in response to MDMA (“Ecstasy”) administration. Eur J Pharmacol 555:194–198 · DOI
- McPherson PS, Kim YK, Valdivia H et al (1991) The brain ryanodine receptor: a caffeine-sensitive calcium release channel. Neuron 7:17–25 · DOI · Paper page
- Mehta MC, Jain AC, Billie M (2004) Effects of cocaine and caffeine alone and in combination on cardiovascular performance: an experimental hemodynamic and coronary flow reserve study in a canine model. Int J Cardiol 97:225–232 · DOI
- Meijer P, Oyen WJ, Dekker D et al (2009) Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection. Arterioscler Thromb Vasc Biol 29:963–968 · DOI
- Melchert PJ, Duncker DJ, Traverse JH, Bache RJ (1999) Role of K(+)(ATP) channels and adenosine in regulation of coronary blood flow in the hypertrophied left ventricle. Am J Physiol 277:H617–H625
- Müller C, Jacobson KA (2010) Xanthines as adenosine receptor antagonists. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
- Myers MG, Basinski A (1992) Coffee and coronary heart disease. Arch Intern Med 152:1767–1772 · DOI · Paper page
- Newton GE, Azevedo ER, Parker JD (1999) Inotropic and sympathetic responses to the intracoronary infusion of a beta2-receptor agonist: a human in vivo study. Circulation 99: 2402–2407 · DOI
- Notarius CF, Rongen GA, Floras JS (2003) Caffeine and coffee tolerance. Circulation 108:e38–e40 · DOI
- Nygard O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, Vollset SE (1997) Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 337:230–236 · DOI · Paper page
- Panagiotakos DB, Pitsavos C, Zampelas A et al (2004) The association between coffee consumption and plasma total homocysteine levels: the “ATTICA” study. Heart Vessels 19:280–286 · DOI
- Paoloni HJ, Wilcken DE (1975) The action of aminophylline on the acutely transplanted dog heart: effect of alpha- and beta-adrenoceptor blockade. Br J Pharmacol 53:163–171 · DOI
- Papamichael CM, Aznaouridis KA, Karatzis EN et al (2005) Effect of coffee on endothelial function in healthy subjects. The role of caffeine. Clin Sci (Lond) 109:55–60 · DOI · Paper page
- Patti G, Pasceri V, Colonna G et al (2007) Atorvastatin pretreatment improves outcomes in patients with acute coronary syndromes undergoing early percutaneous coronary intervention: results of the ARMYDA-ACS randomized trial. J Am Coll Cardiol 49:1272–1278 · DOI · Paper page
- Paynter NP, Yeh HC, Voutilainen S et al (2006) Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus: the atherosclerosis risk in communities study. Am J Epidemiol 164:1075–1084 · DOI
- Pereira MA, Parker ED, Folsom AR (2006) Coffee consumption and risk of type 2 diabetes mellitus: an 11-year prospective study of 28 812 postmenopausal women. Arch Intern Med 166:1311–1316 · DOI
- Persson PB (2001) Tubuloglomerular feedback in adenosine A1 receptor-deficient mice. Am J Physiol Regul Integr Comp Physiol 281:R1361 · DOI
- Phillis JW, Song D, O'Regan MH (1998) The role of adenosine in rat coronary flow regulation during respiratory and metabolic acidosis. Eur J Pharmacol 356:199–206 · DOI
- Pietinen P, Aro A, Tuomilehto J, Uusitalo U, Korhonen H (1990) Consumption of boiled coffee is correlated with serum cholesterol in Finland. Int J Epidemiol 19:586–590 · DOI
- Plagemann PG, Wohlhueter RM (1984) Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in Novikoff rat hepatoma cells by methylxanthines, papaverine, N6-cyclohexyladenosine and N6-phenylisopropyladenosine. Biochem Pharmacol 33:1783–1788 · DOI
- Rakic V, Burke V, Beilin LJ (1999) Effects of coffee on ambulatory blood pressure in older men and women: a randomized controlled trial. Hypertension 33:869–873 · DOI
- Ramakers BP, Pickkers P, Deussen A et al (2008) Measurement of the endogenous adenosine concentration in humans in vivo: methodological considerations. Curr Drug Metab 9:679–685 · DOI
- Rasmussen CA Jr, Sutko JL, Barry WH (1987) Effects of ryanodine and caffeine on contractility, membrane voltage, and calcium exchange in cultured heart cells. Circ Res 60:495–504 · DOI
- Riksen NP, Rongen GA, Smits P (2009) Acute and long-term cardiovascular effects of coffee: implications for coronary heart disease. Pharmacol Ther 121:185–191 · DOI
- Riksen NP, Rongen GA, Yellon D, Smits P (2008) Human in vivo research on the vascular effects of adenosine. Eur J Pharmacol 585:220–227 · DOI
- Riksen NP, Zhou Z, Oyen WJ et al (2006) Caffeine prevents protection in two human models of ischemic preconditioning. J Am Coll Cardiol 48:700–707 · DOI
- Rongen GA, Brooks SC, Ando S, Abramson BL, Floras JS (1998a) Angiotensin AT1 receptor blockade abolishes the reflex sympatho-excitatory response to adenosine. J Clin Invest 101:769–776 · DOI
- Rongen GA, Brooks SC, Ando S, Notarius CF, Floras JS (1998b) Caffeine abstinence augments the systolic blood pressure response to adenosine in humans. Am J Cardiol 81:1382–1385 · DOI
- Rongen GA, Floras JS, Lenders JW, Thien T, Smits P (1997) Cardiovascular pharmacology of purines. Clin Sci (Lond) 92:13–24 · DOI
- Rongen GA, Smits P, Verdonck K et al (1995) Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection. J Clin Invest 95:658–668 · DOI
- Rosmarin PC, Applegate WB, Somes GW (1990) Coffee consumption and blood pressure: a randomized, crossover clinical trial. J Gen Intern Med 5:211–213 · DOI
- Rosner SA, Akesson A, Stampfer MJ, Wolk A (2007) Coffee consumption and risk of myocardial infarction among older Swedish women. Am J Epidemiol 165:288–293 · DOI
- Rutherford JD, Vatner SF, Braunwald E (1981) Effects and mechanism of action of aminophylline on cardiac function and regional blood flow distribution in conscious dogs. Circulation 63:378–387 · DOI
- Sanada S, Asanuma H, Minamino T et al (2004) Optimal windows of statin use for immediate infarct limitation: 5′-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase. Circulation 110:2143–2149 · DOI
- Sattin A, Rall TW (1970) The effect of adenosine and adenine nucleotides on the cyclic adenosine 3′,5′-phosphate content of guinea pig cerebral cortex slices. Mol Pharmacol 6:13–23 · DOI · Paper page
- Sekiguchi F, Miyake Y, Kashimoto T, Sunano S (2002) Unaltered caffeine-induced relaxation in the aorta of stroke-prone spontaneously hypertensive rats (SHRSP). J Smooth Muscle Res 38:11–22 · DOI
- Smits P, Schouten J, Thien T (1989) Cardiovascular effects of two xanthines and the relation to adenosine antagonism. Clin Pharmacol Ther 45:593–599 · DOI
- Smits P, Thien T, Van’t Laar A (1985a) The cardiovascular effects of regular and decaffeinated coffee. Br J Clin Pharmacol 19:852–854 · DOI
- Smits P, Thien T, Laar A (1985b) Circulatory effects of coffee in relation to the pharmacokinetics of caffeine. Am J Cardiol 56:958–963 · DOI
- Song Y, Shryock JC, Knot HJ, Belardinelli L (2001) Selective attenuation by adenosine of arrhythmogenic action of isoproterenol on ventricular myocytes. Am J Physiol Heart Circ Physiol 280:H2789–H2795 · DOI
- Stolzenberg-Solomon RZ, Miller ER III, Maguire MG, Selhub J, Appel LJ (1999) Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population. Am J Clin Nutr 69:467–475 · DOI
- Strandhagen E, Thelle DS (2003) Filtered coffee raises serum cholesterol: results from a controlled study. Eur J Clin Nutr 57:1164–1168 · DOI
- Strandhagen E, Zetterberg H, Aires N et al (2004) The methylenetetrahydrofolate reductase C677T polymorphism is a major determinant of coffee-induced increase of plasma homocysteine: a randomized placebo controlled study. Int J Mol Med 13:811–815
- Superko HR, Bortz W Jr, Williams PT, Albers JJ, Wood PD (1991) Caffeinated and decaffeinated coffee effects on plasma lipoprotein cholesterol, apolipoproteins, and lipase activity: a controlled, randomized trial. Am J Clin Nutr 54:599–605 · DOI
- Superko HR, Myll J, DiRicco C, Williams PT, Bortz WM, Wood PD (1994) Effects of cessation of caffeinated-coffee consumption on ambulatory and resting blood pressure in men. Am J Cardiol 73:780–784 · DOI
- Sutton-Tyrrell K, Najjar SS, Boudreau RM et al (2005) Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation 111:3384–3390 · DOI · Paper page
- Taddei S, Virdis A, Mattei P, Favilla S, Salvetti A (1991) Adenosine causes angiotensin II release in human forearm arterioles. J Hypertens Suppl 9:S232–S233
- Tawfik HE, Schnermann J, Oldenburg PJ, Mustafa SJ (2005) Role of A1 adenosine receptors in regulation of vascular tone. Am J Physiol Heart Circ Physiol 288:H1411–H1416 · DOI
- Thelle DS, Heyden S, Fodor JG (1987) Coffee and cholesterol in epidemiological and experimental studies. Atherosclerosis 67:97–103 · DOI
- Timmers HJ, Rongen GA, Karemaker JM, Wieling WW, Marres HA, Lenders JW (2004) The role of carotid chemoreceptors in the sympathetic activation by adenosine in humans. Clin Sci (Lond) 106:75–82 · DOI
- Tsuzuki J, Newburgh RW (1975) Inhibition of 5′-nucleotidase in rat brain by methylxanthines. J Neurochem 25:895–896 · DOI
- Uiterwaal CS, Verschuren WM, Bueno-de-Mesquita HB et al (2007) Coffee intake and incidence of hypertension. Am J Clin Nutr 85:718–723 · DOI · Paper page
- Urgert R, Katan MB (1997) The cholesterol-raising factor from coffee beans. Annu Rev Nutr 17:305–324 · DOI · Paper page
- Urquhart RA, Broadley KJ (1992a) The effects of P1- and muscarinic-receptor agonists upon cAMP-dependent and independent inotropic responses of guinea-pig cardiac preparations. Gen Pharmacol 23:619–626 · DOI
- Urquhart RA, Broadley KJ (1992b) The indirect negative inotropic effects of the P1-receptor agonist, L-phenylisopropyladenosine, in guinea-pig isolated cardiac preparations: comparison with cromakalim. Can J Physiol Pharmacol 70:910–915 · DOI
- van Dam RM, Feskens EJ (2002) Coffee consumption and risk of type 2 diabetes mellitus. Lancet 360:1477–1478 · DOI · Paper page
- van Dam RM, Willett WC, Manson JE, Hu FB (2006) Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women. Diab Care 29:398–403 · DOI
- van Woudenbergh GJ, Vliegenthart R, van Rooij FJA et al (2008) Coffee consumption and coronary calcification: the Rotterdam coronary calcification study. Arterioscler Thromb Vasc Biol 28:1018–1023 · DOI
- van Dusseldorp M, Smits P, Lenders JW, Thien T, Katan MB (1991) Boiled coffee and blood pressure. A 14-week controlled trial. Hypertension 18:607–613 · DOI
- Varani K, Portaluppi F, Gessi S et al (2000) Dose and time effects of caffeine intake on human platelet adenosine A2A receptors: functional and biochemical aspects. Circulation 102:285–289 · DOI
- Varani K, Portaluppi F, Merighi S, Ongini E, Belardinelli L, Borea PA (1999) Caffeine alters A2A adenosine receptors and their function in human platelets. Circulation 99:2499–2502 · DOI
- Verhoef P, Pasman WJ, Van VT, Urgert R, Katan MB (2002) Contribution of caffeine to the homocysteine-raising effect of coffee: a randomized controlled trial in humans. Am J Clin Nutr 76:1244–1248 · DOI · Paper page
- Weggemans RM, Zock PL, Ordovas JM, Pedro-Botet J, Katan MB (2001a) Apoprotein E genotype and the response of serum cholesterol to dietary fat, cholesterol and cafestol. Atherosclerosis 154:547–555 · DOI
- Weggemans RM, Zock PL, Ordovas JM, Ramos-Galluzzi J, Katan MB (2001b) Genetic polymorphisms and lipid response to dietary changes in humans. Eur J Clin Invest 31:950–957 · DOI
- Wierema TK, Houben AJ, Kroon AA et al (2005) Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients. J Hypertens 23:1731–1736 · DOI
- Winkelmayer WC, Stampfer MJ, Willett WC, Curhan GC (2005) Habitual caffeine intake and the risk of hypertension in women. JAMA 294:2330–2335 · DOI · Paper page
- Woo OF, Pond SM, Benowitz NL, Olson KR (1984) Benefit of hemoperfusion in acute theophylline intoxication. J Toxicol Clin Toxicol 22:411–424 · DOI
- Yang JN, Bjorklund O, Lindstrom-Tornqvist K et al (2009) Mice heterozygous for both A1 and A2A adenosine receptor genes show similarities to mice given long-term caffeine. J Appl Physiol 106:631–639 · DOI
- Ye Y, Abu Said G, Lin Y et al (2008) Caffeinated coffee blunts the myocardial protective effects of statins against ischemia-reperfusion injury in the rat. Cardiovasc Drugs Ther 22:275–282 · DOI
- Yellon DM, Downey JM (2003) Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev 83:1113–1151 · DOI · Paper page
- Zhang W, Lopez-Garcia E, Li TY, Hu FB, van Dam RM (2009) Coffee consumption and risk of cardiovascular diseases and all-cause mortality among men with type 2 diabetes. Diab Care 32:1043–1045 · DOI
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van Dam, R. M., Hu, F. B., & Willett, W. C. (2020) · New England Journal of Medicine · doi:10.1056/nejmra1816604 · Cited by 508
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Stohs, S. J., Preuss, H. G., & Shara, M. (2012) · International Journal of Medical Sciences · doi:10.7150/ijms.4446 · Cited by 115
Caffeine reduces myocardial blood flow during exercise
Higgins, J. P., & Babu, K. M. (2013) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.12.023 · Cited by 85
Assessing caffeine intake in the United Kingdom diet
Fitt, E., Pell, D., & Cole, D. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2012.07.092 · Cited by 74
Sampaio-Jorge, F., Morales, A. P., Pereira, R., Barth, T., & Ribeiro, B. G. (2021) · Scientific Reports · doi:10.1038/s41598-021-03158-2 · Cited by 15
Endogenous adenosine release is involved in the control of heart rate in rats
Jammes, Y., Joulia, F., Steinberg, J. G., Ravailhe, S., Delpierre, S., Condo, J., Guieu, R., & Delliaux, S. (2015) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0042 · Cited by 11
Han, S., Qiu, Y., Zhang, G. Q., Lian, F., & Zhang, W. (2024) · Nutrition Reviews · doi:10.1093/nutrit/nuad110 · Cited by 6
Metadata
- Authors
- Riksen, N. P., Smits, P., & Rongen, G. A.
- Venue
- Handbook of Experimental Pharmacology
- Publisher
- Springer Berlin Heidelberg
- Published
- 2010-08-19
- Pages
- 413-437
- ISSN
- 0171-2004
- 1865-0325
- Cited by
- 65
- References
- 30
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.