Mitosis Detection in Breast Cancer Histology Images with Deep Neural Networks
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We use deep max-pooling convolutional neural networks to detect mitosis in breast histology images. The networks are trained to classify each pixel in the images, using as context a patch centered on the pixel. Simple postprocessing is then applied to the network output. Our approach won the ICPR 2012 mitosis detection competition, outperforming other contestants by a significant margin.
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Ciresan et al. employed CNNs of 11-13 layers for identifying mitotic figures, attaining recall and precision scores of 0.7 and 0.88 respectively.
“Ciresan et al. [291] employed CNNs of 11–13 layers for identifying mitotic figures. Fifty breast histology images from the MITOS dataset were used. Their technique attained recall and precision scores of 0.7 and 0.88 respectively.”
From Review of deep learning: concepts, CNN architectures, challenges, applications, future directions (2021) · cites this paper as [291]
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- Authors
- Cireşan, D. C., Giusti, A., Gambardella, L. M., & Schmidhuber, J.
- Affiliations
- University of Applied Sciences and Arts of Southern Switzerland (CH)
- Venue
- Lecture Notes in Computer Science
- Publisher
- Springer Berlin Heidelberg
- Published
- 2013
- Volume
- 16
- Issue
- Pt 2
- Pages
- 411-418
- ISSN
- 0302-9743 (ISSN-L)
- 1611-3349
- OpenAlex
- W22040386
- Cited by
- 1,536
- References
- 20
- Citations by year
- 2026: 21 · 2025: 54 · 2024: 79 · 2023: 100 · 2022: 139 · 2021: 174 · 2020: 183 · 2019: 187 · 2018: 185 · 2017: 178 · 2016: 126 · 2015: 70 · 2014: 35 · 2013: 2 · 2012: 1
- FWCI
- 50.14
- Type
- conference paper
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Lecture notes in computer science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (140399)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Cell Image Analysis Techniques
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Digital Imaging for Blood Diseases
- Keywords
- mitosis detection, breast cancer, histological images, convolutional neural networks, max pooling, pixel classification, post-processing
- MeSH terms
- Algorithms, Biopsy, Breast Neoplasms, Cell Nucleus, Female, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Microscopy, Mitosis, Pattern Recognition, Automated, Sensitivity and Specificity, Reproducibility of Results, Neural Networks, Computer
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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