Cited by 1,536AI in cancer detectionCell Image Analysis TechniquesDigital Imaging for Blood Diseases

Mitosis Detection in Breast Cancer Histology Images with Deep Neural Networks

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Cireşan, Dan C., Giusti, Alessandro, Gambardella, Luca M., Schmidhuber, Jürgen·2013·Lecture Notes in Computer Science

Abstract

We use deep max-pooling convolutional neural networks to detect mitosis in breast histology images. The networks are trained to classify each pixel in the images, using as context a patch centered on the pixel. Simple postprocessing is then applied to the network output. Our approach won the ICPR 2012 mitosis detection competition, outperforming other contestants by a significant margin.

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Crossref · 10.1007/978-3-642-40763-5_51

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  • Ciresan et al. employed CNNs of 11-13 layers for identifying mitotic figures, attaining recall and precision scores of 0.7 and 0.88 respectively.

    “Ciresan et al. [291] employed CNNs of 11–13 layers for identifying mitotic figures. Fifty breast histology images from the MITOS dataset were used. Their technique attained recall and precision scores of 0.7 and 0.88 respectively.”

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  1. Sommer, C., Fiaschi, L., Heidelberg, H., Hamprecht, F., Gerlich, D.: Learning-based mitotic cell detection in histopathological images. In: Proc. ICPR 2012 (2012) 415, 416

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Authors
Cireşan, D. C., Giusti, A., Gambardella, L. M., & Schmidhuber, J.
Affiliations
University of Applied Sciences and Arts of Southern Switzerland (CH)
Venue
Lecture Notes in Computer Science
Published
2013
Volume
16
Issue
Pt 2
Pages
411-418
ISSN
  • 0302-9743 (ISSN-L)
  • 1611-3349
OpenAlex
W22040386
Cited by
1,536
References
20
Citations by year
2026: 21 · 2025: 54 · 2024: 79 · 2023: 100 · 2022: 139 · 2021: 174 · 2020: 183 · 2019: 187 · 2018: 185 · 2017: 178 · 2016: 126 · 2015: 70 · 2014: 35 · 2013: 2 · 2012: 1
FWCI
50.14
Type
conference paper
Language
en
Open access
Locations
  • Lecture notes in computer science (publishedVersion)
  • PubMed (publishedVersion)
Funders
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (140399)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Cell Image Analysis Techniques
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Digital Imaging for Blood Diseases
Keywords
mitosis detection, breast cancer, histological images, convolutional neural networks, max pooling, pixel classification, post-processing
MeSH terms
Algorithms, Biopsy, Breast Neoplasms, Cell Nucleus, Female, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Microscopy, Mitosis, Pattern Recognition, Automated, Sensitivity and Specificity, Reproducibility of Results, Neural Networks, Computer

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