Effect of pregnancy on the pharmacokinetics of caffeine

The Pharmacological Basis of Therapeutics

Goodman, L., & Gilman, A. (1976) · Optometry and Vision Science · doi:10.1097/00006324-197604000-00018 · Cited by 17,456 · see citing works

The Pharmacological Basis of Therapeutics

(1976) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/33.4.373a · Cited by 9,216 · see citing works

The pharmacological basis of therapeutics

Frank, A. L. (1981) · Environmental Research · doi:10.1016/0013-9351(81)90176-6 · Cited by 2,738 · see citing works

The pharmacological basis of therapeutics. 6th ed

Atkinson, A. J., & Littman, A. (1981) · Gastroenterology · doi:10.1016/0016-5085(81)90293-6 · Cited by 466 · see citing works

Effect of smoking on caffeine clearance

Parsons, W. D., & Neims, A. H. (1978) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt197824140 · Cited by 302 · see citing works

A STUDY OF THE METABOLISM OF THEOBROMINE, THEOPHYLLINE, AND CAFFEINE IN MAN

Cornish, H. H., & Christman, A. A. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)70714-x · Cited by 302 · see citing works

Therapeutic Drug Monitoring in Saliva

Danhof, M., & Breimer, D. D. (1978) · Clinical Pharmacokinetics · doi:10.2165/00003088-197803010-00003 · Cited by 296 · see citing works

THE FATE OF CAFFEINE IN MAN AND A METHOD FOR ITS ESTIMATION IN BIOLOGICAL MATERIAL

Axelrod, J., & Reichenthal, J. (1953) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)05200-0 · Cited by 242 · see citing works

Use of saliva in therapeutic drug monitoring.

Horning, M. G., Brown, L. S., Nowlin, J., Lertratanangkoon, K., Kellaway, P., & Zion, T. E. (1977) · Clinical Chemistry · doi:10.1093/clinchem/23.2.157 · Cited by 187 · see citing works

Relationship between theophylline concentration in plasma and saliva of man

Koysooko, R., Ellis, E. F., & Levy, G. (1974) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1974155454 · Cited by 147 · see citing works

Concepts in Biochemical Pharmacology

Gillette, J. R., & Mitchell, J. R. (1975) · Springer eBooks · doi:10.1007/978-3-642-46314-3 · Cited by 127 · see citing works

Decreased theophylline half-life in cigarette smokers

Jenne, J. W., Nagasawa, H. T., McHugh, R., MacDonald, F. M., & Wyse, E. P. (1975) · Life Sciences · doi:10.1016/0024-3205(75)90503-2 · Cited by 124 · see citing works

Physiological Disposition of Caffeine

Burg, A. W. (1975) · Drug Metabolism Reviews · doi:10.3109/03602537508993756 · Cited by 114 · see citing works

Caffeine in plasma and saliva by a radioimmunoassay procedure.

Cook, C. E., Tallent, C. R., Amerson, E., Myers, M., Kepler, J. A., Taylor, G. F., & Christensen, H. D. (1976) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)30729-9 · Cited by 81 · see citing works

Indirect Plasma-Theophylline Monitoring in Asthmatic Children by Determination of Theophylline Concentration in Saliva

Levy, G., Ellis, E. F., & Koysooko, R. (1974) · PEDIATRICS · doi:10.1542/peds.53.6.873 · Cited by 63 · see citing works

Identification, kinetic and quantitative study of [2-14C] and [1-Me-14C]caffeine metabolites in rat's urine by chromatographic separations

Arnaud, M. J. (1976) · Biochemical Medicine · doi:10.1016/0006-2944(76)90010-7 · Cited by 54 · see citing works

High performance liquid chromatographic and mass spectrometric identification of dimethylxanthine metabolites of caffeine in human plasma

Midha, K. K., Sved, S., Hossie, R. D., & McGilveray, I. J. (1977) · Journal of Mass Spectrometry · doi:10.1002/bms.1200040309 · Cited by 44 · see citing works

[Are coffee and alcohol consumption risk factors in pregnancy? (author's transl)].

Mau, G., & Netter, P. (1974) · PubMed · Cited by 41 · see citing works

Metabolism of caffeine-3H in the rat*1, *2

KHANNA, K. (1972) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(72)90112-3 · Cited by 38 · see citing works

The human metabolism of caffeine to theophylline.

Sved, S., Rd, H., & McGilveray, I. J. (1976) · PubMed · Cited by 36 · see citing works

Identification of two new metabolites of caffeine in the rat urine

Rao, G. S., Khanna, K. L., & Cornish, H. H. (1973) · Cellular and Molecular Life Sciences · doi:10.1007/bf01930396 · Cited by 24 · see citing works

Metabolism of 1,3,7-trimethyldihydrouric acid in the rat: new metabolic pathway of caffeine

Arnaud, M. J. (1976) · Experientia · doi:10.1007/bf01953069 · Cited by 16 · see citing works

Actions of caffeine in the brain with special reference to factors that contribute to its widespread use

Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01396-6 · Cited by 2,624 · see citing works

Pregnancy-Induced Changes in Pharmacokinetics

Anderson, G. D. (2005) · Clinical Pharmacokinetics · doi:10.2165/00003088-200544100-00001 · Cited by 650 · see citing works

Scientific Opinion on the safety of caffeine

EFSA Panel on Dietetic Products, N. A. A. (. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.4102 · Cited by 613 · see citing works

The Safety of Ingested Caffeine: A Comprehensive Review

Temple, J. L., Bernard, C., Lipshultz, S. E., Czachor, J. D., Westphal, J. A., & Mestre, M. A. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00080 · Cited by 557 · see citing works

Are we dependent upon coffee and caffeine? A review on human and animal data

Nehlig, A. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00050-5 · Cited by 453 · see citing works

Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy: A Database for Parameters Required in Physiologically Based Pharmacokinetic Modelling

Abduljalil, K., Furness, P., Johnson, T. N., Rostami-Hodjegan, A., & Soltani, H. (2012) · Clinical Pharmacokinetics · doi:10.2165/11597440-000000000-00000 · Cited by 371 · see citing works

Caffeine Use in Sports, Pharmacokinetics in Man, and Cellular Mechanisms of Action

Magkos, F., & Kavouras, S. A. (2005) · Critical Reviews in Food Science and Nutrition · doi:10.1080/1040-830491379245 · Cited by 350 · see citing works

Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

Stillhart, C., Vučićević, K. M., Augustijns, P., Basit, A. W., Batchelor, H. K., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., et al. (2020) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2020.105280 · Cited by 326 · see citing works

Metabolic Dynamics and Prediction of Gestational Age and Time to Delivery in Pregnant Women

Liang, L., Rasmussen, M.-L. H., Piening, B., Shen, X., Chen, S., Röst, H. L., Snyder, J. K., Tibshirani, R. J., Skotte, L., Lee, N. C. Y., et al. (2020) · Cell · doi:10.1016/j.cell.2020.05.002 · Cited by 308 · see citing works

Adherence to the Caffeine Intake Guideline during Pregnancy and Birth Outcomes: A Prospective Cohort Study

Peacock, A., Hutchinson, D. M., Wilson, J., McCormack, C. A., Bruno, R., Olsson, C. A., ALLSOP, S. J., Elliott, E. J., Burns, L., & Mattick, R. P. (2018) · Nutrients · doi:10.3390/nu10030319 · Cited by 279 · see citing works

Hazard characterisation of chemicals in food and diet

Dybing, E., Doe, J. E., Groten, J. P., Kleiner, J., O'Brien, J., Renwick, A. G. C., Schlatter, J. R., Steinberg, P., Tritscher, A. M., Walker, R., et al. (2002) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(01)00115-6 · Cited by 269 · see citing works

The Health Consequences of Caffeine

Curatolo, P. W., & ROBERTSON, D. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-5-641 · Cited by 269 · see citing works

Variation in CYP1A2 Activity and its Clinical Implications: Influence of Environmental Factors and Genetic Polymorphisms

Gunes, A., & Dahl, M. (2008) · Pharmacogenomics · doi:10.2217/14622416.9.5.625 · Cited by 257 · see citing works

Are the Current Guidelines on Caffeine Use in Sport Optimal for Everyone? Inter-individual Variation in Caffeine Ergogenicity, and a Move Towards Personalised Sports Nutrition

Pickering, C., & Kiely, J. (2017) · Sports Medicine · doi:10.1007/s40279-017-0776-1 · Cited by 221 · see citing works

Caffeine and cardiovascular health

Turnbull, D., Rodricks, J. V., Mariano, G. F., & Chowdhury, F. (2017) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2017.07.025 · Cited by 216 · see citing works

Coffee and fetal death: a cohort study with prospective data

Bech, B. H., Nohr, E. A., Vaeth, M., Henriksen, T. B., & Olsen, J. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi317 · Cited by 202 · see citing works

Comparing the subjective, psychomotor, and physiological effects of intravenous hydromorphone and morphine in healthy volunteers

Hill, J. L., & Zacny, J. P. (2000) · Psychopharmacology · doi:10.1007/s002130000500 · Cited by 194 · see citing works

Sex-Related Differences in Drug Disposition in Man

Wilson, K. (1984) · Clinical Pharmacokinetics · doi:10.2165/00003088-198409030-00001 · Cited by 163 · see citing works

THE ASSOCIATION BETWEEN LOW BIRTH WEIGHT AND CAFFEINE CONSUMPTION DURING PREGNANCY

MARTIN, T. R., & Bracken, M. B. (1987) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114718 · Cited by 150 · see citing works

Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis

Chen, L.-W., Wu, Y., Neelakantan, N., Chong, M. F.-F., Pan, A., & van Dam, R. M. (2014) · BMC Medicine · doi:10.1186/s12916-014-0174-6 · Cited by 147 · see citing works

Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene.

Nakajima, M., Yokoi, T., Mizutani, M., Shin, S., Kadlubar, F. F., & Kamataki, T. (1994) · PubMed · Cited by 141 · see citing works

The health effects of stimulant drinks

Finnegan, D. (2003) · Nutrition Bulletin · doi:10.1046/j.1467-3010.2003.00345.x · Cited by 131 · see citing works

Potential teratogenic and neurodevelopmental consequences of coffee and caffeine exposure: A review on human and animal data

Nehlig, A., & Debry, G. (1994) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(94)90032-9 · Cited by 129 · see citing works

A pregnancy physiologically based pharmacokinetic (p‐ PBPK ) model for disposition of drugs metabolized by CYP1A2 , CYP2D6 and CYP3A4

Gaohua, L., Abduljalil, K., Jamei, M., Johnson, T. N., & Rostami‐Hodjegan, A. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04363.x · Cited by 128 · see citing works

Alterations in drug disposition during pregnancy:

Hodge, L. S., & Tracy, T. S. (2007) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.3.4.557 · Cited by 114 · see citing works

Maternal caffeine consumption during pregnancy and risk of low birth weight: a dose-response meta-analysis of observational studies

Rhee, J., Kim, R., Kim, Y., Tam, M., Lai, Y., Keum, N., & Oldenburg, C. E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132334 · Cited by 111 · see citing works

A meta-analysis of risk of pregnancy loss and caffeine and coffee consumption during pregnancy

Li, J., Zhao, H., Song, J., Zhang, J., Tang, Y., & Xin, C. (2015) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2015.03.033 · Cited by 102 · see citing works

Pharmacokinetics during pregnancy: evidence-based maternal dose formulation

Little, B. B. (1999) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(98)00444-x · Cited by 102 · see citing works

Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be

James, J. E. (2020) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2020-111432 · Cited by 98 · see citing works

Methylxanthines: Toxicity to humans. 2. Caffeine

Stavrić, B. (1988) · Food and Chemical Toxicology · doi:10.1016/0278-6915(88)90236-0 · Cited by 92 · see citing works

Buprenorphine

Heit, H. A., & Gourlay, D. L. (2008) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e31815ca2b4 · Cited by 87 · see citing works

Cytochrome P450 IA2 Activity in Man Measured by Caffeine Metabolism: Effect of Smoking, Broccoli and Exercise

Vistisen, K. K., Loft, S. H., & Poulsen, H. E. (1991) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-5877-0_55 · Cited by 83 · see citing works

Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes

Jahanfar, S., & Jaafar, S. H. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006965.pub4 · Cited by 81 · see citing works

Using pharmacokinetics to predict the effects of pregnancy and maternal–infant transfer of drugs during lactation

Anderson, G. D. (2006) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2.6.947 · Cited by 81 · see citing works

Obstetric Anaesthetists' Association

Thorburn, J. (1982) · Anaesthesia · doi:10.1111/j.1365-2044.1982.tb01210.x · Cited by 78 · see citing works

Treatment of obstetric post-dural puncture headache. Part 1: conservative and pharmacological management

Russell, R. I., Laxton, C., Lucas, D. N., Niewiarowski, J., Scrutton, M., & Stocks, G. M. (2018) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2018.12.006 · Cited by 76 · see citing works

Mechanism-based Pharmacokinetic–Pharmacodynamic Modeling of the Antinociceptive Effect of Buprenorphine in Healthy Volunteers

Yassen, A., Olofsen, E., Romberg, R. R., Sarton, E. Y., Danhof, M., & Dahan, A. (2006) · Anesthesiology · doi:10.1097/00000542-200606000-00019 · Cited by 76 · see citing works

Effects of single doses of alcohol and caffeine on cigarette smoke puffing behavior

Nil, R., Buzzi, R., & Bättig, K. (1984) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(84)90308-3 · Cited by 72 · see citing works

Adenosine A1 receptor down‐regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats

León, D., Albasanz, J. L., Ruiz, M. A., Fernández, M., & Martı́n, M. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01008.x · Cited by 71 · see citing works

Prediction of maternal pharmacokinetics using physiologically based pharmacokinetic models: assessing the impact of the longitudinal changes in the activity of CYP1A2, CYP2D6 and CYP3A4 enzymes during pregnancy

Abduljalil, K., Pansari, A., & Jamei, M. (2020) · Journal of Pharmacokinetics and Pharmacodynamics · doi:10.1007/s10928-020-09711-2 · Cited by 69 · see citing works

Consequences on the newborn of chronic maternal consumption of coffee during gestation and lactation: a review.

Nehlig, A., & Debry, G. (1994) · Journal of the American College of Nutrition · doi:10.1080/07315724.1994.10718366 · Cited by 69 · see citing works

Dietary effect on mixed function P450 1A2 activity assayed by estimation of caffeine metabolism in man

Kall, M., & Clausen, J. (1995) · Human & Experimental Toxicology · doi:10.1177/096032719501401004 · Cited by 69 · see citing works

A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy

Xia, B., Heimbach, T., Gollen, R., Nanavati, C., & He, H. (2013) · The AAPS Journal · doi:10.1208/s12248-013-9505-3 · Cited by 68 · see citing works

Pregnancy‐induced changes in the pharmacokinetics of caffeine and its metabolites

Tian, Y., Campbell, S., Stockmann, C. R., Tak, C. R., Schoen, K., Clark, E., Varner, M. W., Spigarelli, M. G., & Sherwin, C. M. T. (2015) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.632 · Cited by 67 · see citing works

Metronidazole and Antipyrine as Probes for the Study of Foreign Compound Metabolism

Loft, S. H. (1990) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1990.tb01611.x · Cited by 66 · see citing works

Chronic prenatal caffeine exposure impairs novel object recognition and radial arm maze behaviors in adult rats

Soellner, D., Grandys, T., & Nuñez, J. L. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.08.012 · Cited by 62 · see citing works

Clinical Therapeutics in Pregnancy

Feghali, M. N., & Mattison, D. R. (2011) · BioMed Research International · doi:10.1155/2011/783528 · Cited by 60 · see citing works

The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women

Nordmark, A., Lundgren, S., Ask, B., Granath, F. N., & Rane, A. (2002) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2002.01673.x · Cited by 60 · see citing works

The Biochemistry of Drug Metabolism – An Introduction

Krämer, S. D., & Testa, B. (2008) · Chemistry & Biodiversity · doi:10.1002/cbdv.200890214 · Cited by 59 · see citing works

Caffeine‐induced limb malformations: Description of malformations and quantitation of placental transfer

Scott, W. J. (1983) · Teratology · doi:10.1002/tera.1420280314 · Cited by 59 · see citing works

Accumulation of caffeine in healthy volunteers treated with furafylline.

Tarrus, E., Camı́, J., Roberts, D., Spickett, R. G. W., Celdrán, E., & Segura, J. (1987) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1987.tb03003.x · Cited by 59 · see citing works

An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics

Eke, A. C. (2021) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2021-0312 · Cited by 54 · see citing works

A study of gender-based cytochrome P4501A2 variability: a possible mechanism for the male excess of bladder cancer.

Horn, E. P., Tucker, M. A., Lambert, G. H., Silverman, D. T., Zametkin, D. P., Sinha, R. R., Hartge, T., Landi, M. T., & Caporaso, N. E. (1995) · PubMed · Cited by 51 · see citing works

Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models

Chaphekar, N., Dodeja, P., Shaik, I. H., Caritis, S. N., & Venkataramanan, R. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.733823 · Cited by 50 · see citing works

Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism

Wietholtz, H., Zysset, T., Kreiten, K., Kohl, D., B�chsel, R., & Matern, S. (1989) · European Journal of Clinical Pharmacology · doi:10.1007/bf00558303 · Cited by 50 · see citing works

Labetalol disposition and concentration‐effect relationships during pregnancy.

Rubin, P. C., Butters, L., Kelman, A. W., Fitzsimons, C., & Reid, J. L. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb01531.x · Cited by 50 · see citing works

Drug metabolism in pregnancy, infancy and childhood

Perucca, E. (1987) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(87)90096-9 · Cited by 49 · see citing works

Caffeine disposition in obesity.

Abernethy, D., Todd, E. L., & Schwartz, J. B. (1985) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1985.tb02799.x · Cited by 49 · see citing works

Caffeine Metabolism and the Risk of Spontaneous Abortion of Normal Karyotype Fetuses

Signorello, L. B., Nordmark, A., Granath, F., Blot, W. J., McLaughlin, J. K., Annerén, G., Lundgren, S., Ekbom, A., Rane, A., & Cnattingius, S. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01575-7 · Cited by 47 · see citing works

A Survey of Pharmacokinetic Data from Pregnant Women

CUMMINGS, A. J. (1983) · Clinical Pharmacokinetics · doi:10.2165/00003088-198308040-00005 · Cited by 46 · see citing works

Neurobehavioral hazard identification and characterization for caffeine

Turnbull, D., Rodricks, J. V., & Mariano, G. (2015) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2015.12.002 · Cited by 45 · see citing works

Longitudinal effects of pregnancy on the pharmacokinetics of theophylline

Gardner, M. J., Schatz, M. X., Cousins, L., Zeiger, R. S., Middleton, E., & Jusko, W. J. (1987) · European Journal of Clinical Pharmacology · doi:10.1007/bf00607577 · Cited by 45 · see citing works

Systematic review of randomised controlled trials of the effects of caffeine or caffeinated drinks on blood glucose concentrations and insulin sensitivity in people with diabetes mellitus

Whitehead, N., & White, H. (2013) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12033 · Cited by 41 · see citing works

Repression of Hepatobiliary Transporters and Differential Regulation of Classic and Alternative Bile Acid Pathways in Mice During Pregnancy

Aleksunes, L. M., Yeager, R. L., Wen, X., Cui, J. Y., & Klaassen, C. D. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs248 · Cited by 41 · see citing works

Caffeine: A Multifunctional Efficacious Molecule with Diverse Health Implications and Emerging Delivery Systems

Song, X., Singh, M. V., Lee, K. E., Vinayagam, R., & Kang, S. G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212003 · Cited by 40 · see citing works

How Can Drug Metabolism and Transporter Genetics Inform Psychotropic Prescribing?

Henriques, B. C., Yang, E. H., Lapetina, D. L., Carr, M. S., Yavorskyy, V., Hague, J., & Aitchison, K. J. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.491895 · Cited by 39 · see citing works

The effects of caffeine on physiological functions and mental performance

Bättig, K., Buzzi, R., Martin, J. R., & Feierabend, J. M. (1984) · Cellular and Molecular Life Sciences · doi:10.1007/bf01946650 · Cited by 39 · see citing works

Caffeine and its dimethylxanthines and fetal cerebral development in rat

Tanaka, H., Nakazawa, K., Arima, M., & Iwasaki, S. (1984) · Brain and Development · doi:10.1016/s0387-7604(84)80111-4 · Cited by 36 · see citing works

Caffeine Induces High Expression of cyp-35A Family Genes and Inhibits the Early Larval Development in Caenorhabditis elegans

Min, H., Kawasaki, I., Gong, J., & Shim, Y. (2015) · Molecules and Cells · doi:10.14348/molcells.2015.2282 · Cited by 34 · see citing works

Identification of novel polymorphisms in the 5’ flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance

Aitchison, K. J., Gonzalez, F. J., Quattrochi, L. C., Sapone, A., Zhao, J. H., Zaher, H., Elizondo, G., Bryant, C., Munro, J., Collier, D. A., et al. (2000) · Pharmacogenetics · doi:10.1097/00008571-200011000-00004 · Cited by 34 · see citing works

Rate of Caffeine Metabolism and Risk of Spontaneous Abortion

Fenster, L., Quale, C. M., Hiatt, R. A., Wilson, M., Windham, G. C., & Benowitz, N. L. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009477 · Cited by 33 · see citing works

The Biochemistry of Drug Metabolism – An Introduction

Krämer, S. D., & Testa, B. (2009) · Chemistry & Biodiversity · doi:10.1002/cbdv.200900233 · Cited by 33 · see citing works

Pharmacologic studies in vulnerable populations: Using the pediatric experience

Zimmerman, K. O., González, D., Swamy, G. K., & Cohen‐Wolkowiez, M. (2015) · Seminars in Perinatology · doi:10.1053/j.semperi.2015.08.007 · Cited by 29 · see citing works

Adverse effect of maternal caffeine ingestion on fetal cerebrum in rat

Tanaka, H., Nakazawa, K., & Arima, M. (1983) · Brain and Development · doi:10.1016/s0387-7604(83)80045-x · Cited by 29 · see citing works

The effect of pregnancy on drug pharmacokinetics

Jeffries, W. S., & Bochner, F. (1988) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1988.tb120820.x · Cited by 29 · see citing works

Human drug metabolism in vivo

SITAR, D. S. (1989) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(89)90016-8 · Cited by 27 · see citing works

Protein-Energy Malnutrition in Rats during Pregnancy Modifies the Effects of Caffeine on Fetal Bones

Nakamoto, T., & Shaye, R. (1986) · Journal of Nutrition · doi:10.1093/jn/116.4.633 · Cited by 26 · see citing works

Placental transfer of the major caffeine metabolite in the rat using 6-amino-5[N-formylmethylamino]1,3[Me-14C]-dimethyluracil administered orally or intravenously to the pregnant rat

Arnaud, M. J., Bracco, I., Sauvageat, J.-L., & Clerc, M.-F. (1983) · Toxicology Letters · doi:10.1016/0378-4274(83)90187-x · Cited by 25 · see citing works

Determination of methylxanthine contents and risk characterisation for various types of tea in Korea

Baek, G.-H., Yang, S.-W., Yun, C., Lee, J.-G., & Kim, Y. (2021) · Food Control · doi:10.1016/j.foodcont.2021.108543 · Cited by 25 · see citing works

THE RELEVANCE OF ETHNIC INFLUENCES ON PHARMACOGENETICS TO THE TREATMENT OF PSYCHOSIS

Aitchison, K. J., Barry D. Jordan, & Sharma, T. (2000) · Drug metabolism and drug interactions · doi:10.1515/dmdi.2000.16.1.15 · Cited by 25 · see citing works

Caffeine: Clinical and experimental effects in humans

Bruce, M. S., & LADER, M. H. (1986) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.470010203 · Cited by 25 · see citing works

Caffeine Reduces 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in Human Trophoblast Cells through the Adenosine A2B Receptor

Sharmin, S., Guan, H., Williams, A. S., & Yang, K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038082 · Cited by 24 · see citing works

The complexity of coffee and its impact on metabolism

Zhang, H., & Speakman, J. R. (2024) · Journal of Endocrinology · doi:10.1530/joe-24-0075 · Cited by 22 · see citing works

Pharmacokinetics of buprenorphine following intravenous administration in dogs

Krotscheck, U., Boothe, D. M., & Little, A. A. (2008) · American Journal of Veterinary Research · doi:10.2460/ajvr.69.6.722 · Cited by 22 · see citing works

Maternal tea consumption and the risk of preterm delivery in urban China: a birth cohort study

Huang, L., Lerro, C. C., Yang, T., Li, J., Qiu, J., Qiu, W., He, X., Cui, H., Lv, L., Xu, R., et al. (2016) · BMC Public Health · doi:10.1186/s12889-016-3100-3 · Cited by 22 · see citing works

Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation

Chen, X., Zhang, L., Yang, D., Li, C., An, G., Wang, J., Shao, Y., Fan, R., & Ma, Q. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00108 · Cited by 21 · see citing works

Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome

Jahanfar, S., & Jaafar, S. H. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006965.pub3 · Cited by 21 · see citing works

Coffee Intake during Pregnancy and Lactation in Rats: Maternal and Pup Hematological Parameters and Liver Iron, Zinc and Copper Concentration

Muñoz, L. M., Keen, C. L., Lönnerdal, B. L., & Dewey, K. G. (1986) · Journal of Nutrition · doi:10.1093/jn/116.7.1326 · Cited by 20 · see citing works

Caffeine intake in pregnancy: relationship between internal intake and effect on birth weight

Partosch, F., Mielke, H., Stahlmann, R., & Gundert-Remy, U. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.11.005 · Cited by 19 · see citing works

Pharmacokinetics and metabolism of salbutamol in premature labour.

Hutchings, M., Paull, J., Wilson‐Evered, E., & Morgan, D. J. (1987) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1987.tb03138.x · Cited by 19 · see citing works

Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats

Shively, C. A., & Tarka, S. M. (1983) · Toxicology and Applied Pharmacology · doi:10.1016/0041-008x(83)90321-6 · Cited by 19 · see citing works

Interaction between ethanol and caffeine in operant behavior of rats

Elsner, J., Alder, S., & Zbinden, G. (1988) · Psychopharmacology · doi:10.1007/bf00177560 · Cited by 19 · see citing works

Coffee consumption during pregnancy — what the gynecologist should know? Review of the literature and clinical studies

Surma, S., & Witek, A. (2022) · Ginekologia Polska · doi:10.5603/gp.a2022.0061 · Cited by 17 · see citing works

Effects of caffeine on the fetal heart

Resch, B. A., & Papp, J. G. (1983) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(83)91070-0 · Cited by 17 · see citing works

Consumo de cafeína e de alimentos-fonte de cafeína e prematuridade: um estudo caso-controle

de Souza, R. A. G., & Sichieri, R. (2005) · Cadernos de Saúde Pública · doi:10.1590/s0102-311x2005000600042 · Cited by 16 · see citing works

Potentiating effect of caffeine on embryotoxicity of cyclophosphamide treatment in vivo during the preimplanation period

Vogel, R. W., & Spielmann, H. (1987) · Teratogenesis Carcinogenesis and Mutagenesis · doi:10.1002/tcm.1770070207 · Cited by 16 · see citing works

Prediction of Xenobiotic Metabolism by Non‐Invasive Methods

Loft, S. H., & Poulsen, H. E. (1990) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1990.tb00793.x · Cited by 15 · see citing works

Maternal caffeine intake during pregnancy and the risk of delivering a small for gestational age baby: Kuopio Birth Cohort

Kukkonen, A., Hantunen, S., Voutilainen, A., Ruusunen, A. A., Backman, K., Kirjavainen, P. V., Ylilauri, M. P., Voutilainen, R., Pasanen, M., & Keski‐Nisula, L. (2024) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-024-07538-7 · Cited by 14 · see citing works

Developmental Neurotoxicity of Alcohol and Anesthetic Drugs Is Augmented by Co-Exposure to Caffeine

Yuede, C. M., Olney, J. W., & Creeley, C. E. (2013) · Brain Sciences · doi:10.3390/brainsci3031128 · Cited by 14 · see citing works

Association between self-reported caffeine intake during pregnancy and social responsiveness scores in childhood: The EARLI and HOME studies

Patti, M. A., Li, N., Eliot, M., Newschaffer, C. J., Yolton, K. A., Khoury, J. C., Chen, A., Lanphear, B. P., Lyall, K., Hertz‐Picciotto, I., et al. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245079 · Cited by 13 · see citing works

The effect of pregnancy on the pharmacokinetics of caffeine

Knutti, R., Rothweiler, H., & Schlatter, C. (1982) · Archives of Toxicology · doi:10.1007/978-3-642-68511-8_33 · Cited by 106 · see citing works

Placental transfer and foetal disposition of caffeine and its immediate metabolites in the 20-day pregnant rat: function of dose

Abdi, F. B., Pollard, I., & Wilkinson, J. (1993) · Xenobiotica · doi:10.3109/00498259309057033 · Cited by 27 · see citing works

Pharmacokinetics of caffeine during and after pregnancy

Brazier, J. L., Ritter, J., Berland, M., Khenfer, D., & Faucon, G. (2017) · Developmental Pharmacology and Therapeutics · doi:10.1159/000457332 · Cited by 155 · see citing works

The effect of caffeine ingestion on pharmacokinetics of caffeine and its metabolites after a single administration in pregnant rats.

Nakazawa, K., Tanaka, H., & Arima, M. (1985) · Journal of Pharmacobio-Dynamics · doi:10.1248/bpb1978.8.151 · Cited by 16 · see citing works

Pregnancy‐induced changes in the pharmacokinetics of caffeine and its metabolites

Tian, Y., Campbell, S., Stockmann, C. R., Tak, C. R., Schoen, K., Clark, E., Varner, M. W., Spigarelli, M. G., & Sherwin, C. M. T. (2015) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.632 · Cited by 67 · see citing works