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Caffeine as a psychomotor stimulant: mechanism of action
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Parallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527
Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01396-6 · Cited by 2,624
Association of coffee and caffeine intake with the risk of Parkinson disease
Ross, G. W. (2000) · JAMA · doi:10.1001/jama.283.20.2674 · Cited by 778
Prospective Study of Caffeine Consumption and Risk of Parkinson’s Disease in Men and Women
Ascherio, A., Zhang, S. M., Hernán, M. A., Kawachi, I., Colditz, G. A., Speizer, F. E., & Willett, W. C. (2001) · Annals of Neurology · doi:10.1002/ana.1052 · Cited by 677
Are we dependent upon coffee and caffeine? A review on human and animal data
Nehlig, A. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00050-5 · Cited by 453
Caffeine disposition after oral doses
Bonati, M., Latini, R., Galletti, F., Young, J. F., Tognoni, G., & Garattini, S. (1982) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1982.132 · Cited by 353
Caffeine Induces Dopamine and Glutamate Release in the Shell of the Nucleus Accumbens
Solinas, M., Ferré, S., You, Z.-B., Karcz-Kubicha, M., Popoli, P., & Goldberg, S. R. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06321.2002 · Cited by 338
Increases in cortical acetylcholine release during sustained attention performance in rats
Himmelheber, A. M., Sarter, M., & Bruno, J. P. (2000) · Cognitive Brain Research · doi:10.1016/s0926-6410(00)00012-4 · Cited by 261
Recent advances in the molecular biology of nucleoside transporters of mammalian cells
Cass, C. E., Young, J. D., & Baldwin, S. A. (1998) · Biochemistry and Cell Biology · doi:10.1139/o98-095 · Cited by 185
Caffeine Withdrawal: A Parametric Analysis of Caffeine Dosing Conditions
Evans, S. M., & Griffiths, R. R. (1999) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38135-2 · Cited by 145
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Coffee and Health: A Review of Recent Human Research
Higdon, J. V., & Frei, B. (2006) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390500400009 · Cited by 1,090
A Review of Caffeine’s Effects on Cognitive, Physical and Occupational Performance
McLellan, T. M., Caldwell, J. A., & Lieberman, H. R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.09.001 · Cited by 840
Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine
Huang, Z.-L., Qu, W.-M., Eguchi, N., Chen, J.-F., Schwarzschild, M. A., Fredholm, B. B., Urade, Y., & Hayaishi, O. (2005) · Nature Neuroscience · doi:10.1038/nn1491 · Cited by 640
Scientific Opinion on the safety of caffeine
EFSA Panel on Dietetic Products, N. A. A. (. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.4102 · Cited by 613
“Its mechanism of action appears to be substantially different from that of “dopaminomimetic” psychostimulants, such as cocaine and amphetamine (Fisone et al., 2004; Ferre, 2008).”
BackgroundSleep and anxiety: From mechanisms to interventions
Chellappa, S. L., & Aeschbach, D. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101583 · Cited by 509
Coffee, CYP1A2 genotype, and risk of myocardial infarction
Cornelis, M. C., El-Sohemy, A., Kabagambe, E. K., & Campos, H. (2006) · JAMA · doi:10.1001/jama.295.10.1135 · Cited by 490
Samuels, E., & Szabadi, E. (2008) · Current Neuropharmacology · doi:10.2174/157015908785777193 · Cited by 454
An Update on the Mechanisms of the Psychostimulant Effects of Caffeine
Ferré, S. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05196.x · Cited by 440
Arendash, G. W., Mori, T., Cao, C., Mamcarz, M., Runfeldt, M., Dickson, A., Rezai-Zadeh, K., Tan, J., Citron, B. A., Lin, X., et al. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1087 · Cited by 308
Caffeine as an Attention Enhancer: Reviewing Existing Assumptions
Einöther, S. J. L., & Giesbrecht, T. (2013) · Psychopharmacology · doi:10.1007/s00213-012-2917-4 · Cited by 215
Coffee components and cardiovascular risk: beneficial and detrimental effects
Godos, J., Pluchinotta, F. R., Marventano, S., Buscemi, S., Li Volti, G., Galvano, F., & Grosso, G. (2014) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2014.940287 · Cited by 210
Caffeine and risk of Parkinson’s disease in a large cohort of men and women
Palacios, N., Gao, X., McCullough, M. L., Schwarzschild, M. A., Shah, R., Gapstur, S., & Ascherio, A. (2012) · Movement Disorders · doi:10.1002/mds.25076 · Cited by 185
Sleep Loss Produces False Memories
Diekelmann, S., Landolt, H.-P., Lahl, O., Born, J., & Wagner, U. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003512 · Cited by 103
Arab, L., Biggs, M. L., O'Meara, E. S., Longstreth, W. T., Crane, P. K., & Fitzpatrick, A. L. (2011) · Journal of Alzheimer's Disease · doi:10.3233/jad-2011-110431 · Cited by 98
Pfaus, J. G., Wilkins, M. F., DiPietro, N., Benibgui, M., Toledano, R., Rowe, A., & Couch, M. C. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.10.004 · Cited by 63
Sleep is more sensitive to high doses of caffeine in the middle years of life
Robillard, R., Bouchard, M., Cartier, A., Nicolau, L., & Carrier, J. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881115575535 · Cited by 53
Lane, S., Palmer, J., Christie, B., Ehlting, J., & Le, C. (2017) · The Arbutus Review · doi:10.18357/tar81201716816 · Cited by 26
Effects of caffeine on exercise performance in sedentary females.
(2010) · Europe PMC (PubMed Central) · Cited by 25
Silva, H., Del Coso, J., & Pickering, C. (2025) · Sports Medicine · doi:10.1007/s40279-025-02245-y · Cited by 21
Caffeine intake in pregnancy: relationship between internal intake and effect on birth weight
Partosch, F., Mielke, H., Stahlmann, R., & Gundert-Remy, U. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.11.005 · Cited by 19
Giblin, K. A., Basili, D., Afzal, A. M., Rosenbrier-Ribeiro, L., Greene, N., Barrett, I., Hughes, S. J., & Bender, A. (2021) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.0c00311 · Cited by 18
Metadata
- Authors
- Fisone, G., Borgkvist, A., & Usiello, A.
- Venue
- Cellular and Molecular Life Sciences (CMLS)
- Published
- 2004-04-01
- Volume
- 61
- Issue
- 7-8
- Pages
- 857-872
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- OpenAlex
- W2022599378
- Cited by
- 538
- References
- 10
- FWCI
- 6.92
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.