Fox-1 family of RNA-binding proteins
Open accessAbstract
The Fox-1 family of RNA-binding proteins are evolutionarily conserved regulators of tissue-specific alternative splicing in metazoans. The Fox-1 family specifically recognizes the (U)GCAUG stretch in regulated exons or in flanking introns, and either promotes or represses target exons. Recent unbiased bioinformatics analyses of alternatively spliced exons and comparison of various vertebrate genomes identified the (U)GCAUG stretch as a highly conserved and widely distributed element enriched in intronic regions surrounding exons with altered inclusion in muscle, heart, and brain, consistent with specific expression of Fox-1 and Fox-2 in these tissues. Global identification of Fox-2 target RNAs in living cells revealed that many of the Fox-2 target genes themselves encode splicing regulators. Further systematic elucidation of target genes of the Fox-1 family and other splicing regulators in various tissues will lead to a comprehensive understanding of splicing regulatory networks.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
RBFOX binding upstream of, or within, an alternative exon typically inhibits exon inclusion, whereas downstream binding usually promotes splicing.
“RBFOX binding upstream of, or within, an alternative exon typically inhibits exon inclusion, whereas downstream binding usually promotes splicing48.”
From The neurogenetics of alternative splicing (2016) · cites this paper as [48]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
MOLMOL: A program for display and analysis of macromolecular structures
Koradi, R., Billeter, M., & Kurt Wüthrich, A. (1996) · Journal of Molecular Graphics · doi:10.1016/0263-7855(96)00009-4 · Cited by 7,163 · see citing works
Alternative isoform regulation in human tissue transcriptomes
Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature · doi:10.1038/nature07509 · Cited by 5,181 · see citing works
Pan, Q., Shai, O., Lee, L. J., Frey, B. J., & Blencowe, B. J. (2008) · Nature Genetics · doi:10.1038/ng.259 · Cited by 3,951 · see citing works
Mechanisms of Alternative Pre-Messenger RNA Splicing
Black, D. L. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161720 · Cited by 2,704 · see citing works
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
Licatalosi, D. D., Mele, A., Fak, J. J., Ule, J., Kayikci, M., Chi, S. W., Clark, T. A., Schweitzer, A. C., Blume, J. E., Wang, X., et al. (2008) · Nature · doi:10.1038/nature07488 · Cited by 1,352 · cited 2× · see citing works
“These stories are reminiscent of the CLIP-seq analysis of NOVA that led to the discovery that NOVA interacts with 30 UTRs of target mRNAs and regulates alternative polyadenylation in the brain [43].”
MethodUnderstanding alternative splicing: towards a cellular code
Matlin, A. J., Clark, F., & Smith, C. W. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1645 · Cited by 1,299 · see citing works
Alternative splicing: increasing diversity in the proteomic world
Graveley, B. R. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(00)02176-4 · Cited by 1,228 · see citing works
Maris, C., Dominguez, C., & Allain, F. H. ‐. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04653.x · Cited by 1,135 · see citing works
Lim, J., Hao, T., Shaw, C., Patel, A. J., Szabó, G., Rual, J.-F., Fisk, C. J., Li, N., Smolyar, A., Hill, D. E., et al. (2006) · Cell · doi:10.1016/j.cell.2006.03.032 · Cited by 789 · see citing works
Yeo, G. W., Coufal, N. G., Liang, T. Y., Peng, G. E., Fu, X.-D., & Gage, F. H. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1545 · Cited by 572 · see citing works
ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing
Warzecha, C. C., Sato, T. K., Nabet, B., Hogenesch, J. B., & Carstens, R. P. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.01.025 · Cited by 570 · see citing works
Protein Diversity from Alternative Splicing
Black, D. L. (2000) · Cell · doi:10.1016/s0092-8674(00)00128-8 · Cited by 565 · see citing works
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
Shi, Y., Giammartino, D. C. D., Taylor, D. J., Sarkeshik, A., Rice, W. J., Yates, J. R., Frank, J., & Manley, J. L. (2009) · Molecular Cell · doi:10.1016/j.molcel.2008.12.028 · Cited by 560 · see citing works
Rules for Nuclear Localization Sequence Recognition by Karyopherinβ2
Lee, B. J., Cansizoglu, A. E., Süel, K. E., Louis, T. H., Zhang, Z., & Chook, Y. M. (2006) · Cell · doi:10.1016/j.cell.2006.05.049 · Cited by 555 · see citing works
Different levels of alternative splicing among eukaryotes
Kim, E., Magen, A., & Ast, G. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl924 · Cited by 545 · see citing works
An RNA map predicting Nova-dependent splicing regulation
Ule, J., Stefani, G., Mele, A., Ruggiu, M., Wang, X., Taneri, B., Gaasterland, T., Blencowe, B. J., & Darnell, R. B. (2006) · Nature · doi:10.1038/nature05304 · Cited by 528 · see citing works
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
Kalsotra, A., Xiao, X., Ward, A. J., Castle, J. C., Johnson, J. M., Burge, C. B., & Cooper, T. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809045105 · Cited by 508 · see citing works
Cancer-associated regulation of alternative splicing
Venables, J. P., Klinck, R., Koh, C., Gervais-Bird, J., Bramard, A., Inkel, L., Durand, M., Couture, S., Froehlich, U., Lapointe, E., et al. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1608 · Cited by 340 · see citing works
Castle, J. C., Zhang, C., Shah, J. K., Kulkarni, A., Kalsotra, A., Cooper, T. A., & Johnson, J. M. (2008) · Nature Genetics · doi:10.1038/ng.264 · Cited by 319 · see citing works
Jin, Y., Suzuki, H., Maegawa, S., Endo, H., Sugano, S., Hashimoto, K., Yasuda, K., & Inoue, K. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg089 · Cited by 311 · see citing works
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2
Zhang, C., Zhang, Z., Castle, J., Sun, S., Johnson, J., Krainer, A. R., & Zhang, M. Q. (2008) · Genes & Development · doi:10.1101/gad.1703108 · Cited by 300 · see citing works
Underwood, J. G., Boutz, P. L., Dougherty, J. D., Stoilov, P., & Black, D. L. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.10005-10016.2005 · Cited by 272 · see citing works
Molecular basis of RNA recognition by the human alternative splicing factor Fox-1
Auweter, S. D., Fasan, R., Reymond, L., Underwood, J. G., Black, D. L., Pitsch, S., & Allain, F. H. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7600918 · Cited by 264 · see citing works
The splicing regulator TIA‐1 interacts with U1‐C to promote U1 snRNP recruitment to 5′ splice sites
Förch, P., Puig, Ó., Martínez, C., Séraphin, B., & Valcárcel, J. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf668 · Cited by 229 · see citing works
A novel protein with RNA-binding motifs interacts with ataxin-2
Shibata, H. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.9.1303 · Cited by 221 · see citing works
Unusual Intron Conservation near Tissue-Regulated Exons Found by Splicing Microarrays
Sugnet, C. W., Srinivasan, K., Clark, T. A., O’Brien, G. S., Cline, M., Wang, H., Williams, A., Kulp, D., Blume, J. E., Haussler, D. H., et al. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020004 · Cited by 194 · see citing works
Burdine, R. D., Branda, C., & Stern, M. (1998) · Development · doi:10.1242/dev.125.6.1083 · Cited by 194 · see citing works
DeVore, D. L., Horvitz, H. R., & Stern, M. (1995) · Cell · doi:10.1016/0092-8674(95)90101-9 · Cited by 189 · see citing works
Nakahata, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki338 · Cited by 182 · see citing works
The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex
Carmi, I., Kopczynski, J. B., & Meyer, B. J. (1998) · Nature · doi:10.1038/24164 · Cited by 160 · see citing works
Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements
Yeo, G. W.-M., Nostrand, E. L. V., & Liang, T. Y. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030085 · Cited by 158 · see citing works
Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element.Preprint
Huh, G. S., & Hynes, R. O. (1994) · Genes & Development · doi:10.1101/gad.8.13.1561 · Cited by 155 · see citing works
Southby, J., Gooding, C., & Smith, C. W. J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.4.2699 · Cited by 139 · see citing works
Modafferi, E. F., & Black, D. L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.11.6537 · Cited by 132 · see citing works
hnRNP H and hnRNP F Complex with Fox2 To Silence Fibroblast Growth Factor Receptor 2 Exon IIIc
Mauger, D., Lin, C., & García-Blanco, M. A. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00739-08 · Cited by 132 · see citing works
Burdine, R. D., Chen, E. B., Kwok, S. F., & Stern, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.6.2433 · Cited by 131 · see citing works
Meyer, B. J. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(00)02004-7 · Cited by 127 · see citing works
Alternative Splicing Events Identified in Human Embryonic Stem Cells and Neural Progenitors
Yeo, G. W.-M., Xu, X., Liang, T. Y., Muotri, A. R., Carson, C. T., Coufal, N. G., & Gage, F. H. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030196 · Cited by 122 · see citing works
Ponthier, J. L., Schluepen, C., Chen, W., Lersch, R., Gee, S. L., Hou, V., Lo, A., Short, S. A., Chasis, J. A., Winkelmann, J. C., et al. (2006) · eScholarship (California Digital Library) · Cited by 119 · see citing works
Brudno, M. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.11.2338 · Cited by 119 · see citing works
Fox-2 Mediates Epithelial Cell-Specific Fibroblast Growth Factor Receptor 2 Exon Choice
Baraniak, A. P., Chen, J. R., & García-Blanco, M. A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.4.1209-1222.2006 · Cited by 117 · see citing works
Oltean, S., Sorg, B. S., Albrecht, T. R., Bonano, V. I., Brazas, R. M., Dewhirst, M. W., & García-Blanco, M. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603090103 · Cited by 114 · see citing works
Species-specific variation of alternative splicing and transcriptional initiation in six eukaryotes
Nagasaki, H., Arita, M., Nishizawa, T., Suwa, M., & Gotoh, O. (2005) · Gene · doi:10.1016/j.gene.2005.07.027 · Cited by 112 · see citing works
Kuroyanagi, H., Kobayashi, T., Mitani, S., & Hagiwara, M. (2006) · Nature Methods · doi:10.1038/nmeth944 · Cited by 109 · see citing works
Self-citationOgura, K., Kishimoto, N., Mitani, S., Gengyo‐Ando, K., & Kohara, Y. (2003) · Development · doi:10.1242/dev.00469 · Cited by 109 · see citing works
X-chromosome-counting mechanisms that determine nematode sex
Nicoll, M., Akerib, C. C., & Meyer, B. J. (1997) · Nature · doi:10.1038/40669 · Cited by 108 · see citing works
Alternative Splicing of the Fibronectin EIIIB Exon Depends on Specific TGCATG Repeats
Lim, L. P., & Sharp, P. A. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.7.3900 · Cited by 107 · see citing works
Ohkura, N., Takahashi, M., Yaguchi, H., Nagamura, Y., & Tsukada, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502173200 · Cited by 105 · see citing works
Minovitsky, S. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki210 · Cited by 103 · see citing works
xo1-1 acts as an early switch in the C. elegans male/hermaphrodite decision
Rhind, N., Miller, L. M., Kopczynski, J. B., & Meyer, B. J. (1995) · Cell · doi:10.1016/0092-8674(95)90452-2 · Cited by 95 · see citing works
Intronic Alternative Splicing Regulators Identified by Comparative Genomics in Nematodes
Kabat, J. L., Barberán-Soler, S., McKenna, P., Clawson, H., Farrer, T., & Zahler, A. M. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020086 · Cited by 93 · see citing works
The Fox-1 Family and SUP-12 Coordinately Regulate Tissue-Specific Alternative Splicing In Vivo
Kuroyanagi, H., Ohno, G., Mitani, S., & Hagiwara, M. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01508-07 · Cited by 91 · see citing works
Self-citationBaraniak, A. P., Lasda, E. L., Wagner, E. J., & García-Blanco, M. A. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.24.9327-9337.2003 · Cited by 89 · see citing works
Das, D., Clark, T. A., Schweitzer, A. C., Yamamoto, M. L., Marr, H., Arribere, J., Minovitsky, S., Poliakov, A., Dubchak, I. L., Blume, J. E., et al. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm485 · Cited by 89 · see citing works
Developmental Control of CaV1.2 L-Type Calcium Channel Splicing by Fox Proteins
Tang, Z. Z., Zheng, S., Nikolic, J. M., & Black, D. L. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00608-09 · Cited by 82 · see citing works
Hodgkin, J., Zellan, J. D., & Albertson, D. G. (1994) · Development · doi:10.1242/dev.120.12.3681 · Cited by 77 · see citing works
Kawamoto, S. (1996) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86956-9 · Cited by 74 · see citing works
Regulation of alternative splicing of α‐actinin transcript by Bruno‐like proteins
Suzuki, H., Jin, Y., Otani, H., Yasuda, K., & Inoue, K. (2002) · Genes to Cells · doi:10.1046/j.1356-9597.2001.00506.x · Cited by 67 · see citing works
Zhou, H.-L., Baraniak, A. P., & Lou, H. J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.01015-06 · Cited by 66 · see citing works
Goodman, S. J., Branda, C., Robinson, M. K., Burdine, R. D., & Stern, M. (2003) · Development · doi:10.1242/dev.00604 · Cited by 66 · see citing works
Deguillien, M., Huang, S., Morinière, M., Dreumont, N., Benz, E. J. J., & Baklouti, F. (2001) · Blood · doi:10.1182/blood.v98.13.3809 · Cited by 61 · see citing works
Skipper, M., Milne, C. A., & Hodgkin, J. (1999) · Genetics · doi:10.1093/genetics/151.2.617 · Cited by 58 · see citing works
The search for alternative splicing regulators: new approaches offer a path to a splicing codePreprint
David, C. J., & Manley, J. L. (2008) · Genes & Development · doi:10.1101/gad.1643108 · Cited by 58 · see citing works
Control of alternative pre-mRNA splicing by distributed pentameric repeats
Hedjran, F., Yeakley, J. M., Huh, G. S., Hynes, R. O., & Rosenfeld, M. G. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12343 · Cited by 55 · see citing works
Kent, O. A., Ritchie, D. B., & MacMillan, A. M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.25.1.233-240.2005 · Cited by 48 · see citing works
Newman, E. A., Muh, S. J., Hovhannisyan, R. H., Warzecha, C. C., Jones, R. B., McKeehan, W. L., & Carstens, R. P. (2006) · RNA · doi:10.1261/rna.34906 · Cited by 47 · see citing works
Fukumura, K., Kato, A., Jin, Y., Ideue, T., Hirose, T., Kataoka, N., Fujiwara, T., Sakamoto, H., & Inoue, K. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm569 · Cited by 44 · see citing works
Human transformer 2β and SRp55 interact with a calcitonin-specific splice enhancer
Tran, Q. K., Coleman, T. P., & Roesser, J. R. (2003) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(02)00600-0 · Cited by 40 · see citing works
Regulated Fox-2 isoform expression mediates protein 4.1R splicing during erythroid differentiation
Yang, G., Huang, S.-C., Wu, J. Y., & Benz, E. J. J. (2007) · Blood · doi:10.1182/blood-2007-01-068940 · Cited by 39 · see citing works
SRp55 Is a Regulator of Calcitonin/CGRP Alternative RNA Splicing
Tran, Q. K., & Roesser, J. R. (2003) · Biochemistry · doi:10.1021/bi026753a · Cited by 37 · see citing works
Alternative splicing in C. elegans
Zahler, A. M. (2005) · WormBook · doi:10.1895/wormbook.1.31.1 · Cited by 36 · see citing works
A pair as a minimum: The two fibroblast growth factors of the nematode Caenorhabditis elegans
Birnbaum, D., Popovici, C., & Roubin, R. (2004) · Developmental Dynamics · doi:10.1002/dvdy.20219 · Cited by 36 · see citing works
Revisiting the X:A Signal That Specifies Caenorhabditis elegans Sexual Fate
Gladden, J. M., Farboud, B., & Meyer, B. J. (2007) · Genetics · doi:10.1534/genetics.107.078071 · Cited by 36 · see citing works
U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing
Fukumura, K., Taniguchi, I., Sakamoto, H., Ohno, M., & Inoue, K. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp050 · Cited by 35 · see citing works
Muscle-specific Exonic Splicing Silencer for Exon Exclusion in Human ATP Synthase γ-Subunit Pre-mRNA
Hayakawa, M., Sakashita, E., Ueno, E., Tominaga, S., Hamamoto, T., Kagawa, Y., & Endo, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110138200 · Cited by 30 · see citing works
Repression of Prespliceosome Complex Formation at Two Distinct Steps by Fox-1/Fox-2 Proteins
Zhou, H.-L., & Lou, H. J. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00530-08 · Cited by 30 · see citing works
Imaging the alternative silencing ofFGFR2exon IIIb in vivo
Bonano, V. I., Oltean, S., Brazas, R. M., & García-Blanco, M. A. (2006) · RNA · doi:10.1261/rna.248506 · Cited by 26 · see citing works
Expression of a novel DnaJA1 alternative splicing in human testis and sperm
Hu, Y., Zhou, Z., Huang, X., Xu, M., Lü, L., Xu, Z., Li, J., & Sha, J. (2004) · International Journal of Andrology · doi:10.1111/j.1365-2605.2004.00492.x · Cited by 14 · see citing works
Ponthier, J. L., Schluepen, C., Chen, W., Lersch, R. A., Gee, S. L., Hou, V. C., Lo, A. J., Short, S. A., Chasis, J. A., Winkelmann, J. C., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511556200
Flagged first, then by citations
Cited by
Sorted by citations
Mechanisms and Consequences of Alternative Polyadenylation
Di Giammartino, D. C., Nishida, K., & Manley, J. L. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.017 · Cited by 737 · see citing works
Evolution of SR protein and hnRNP splicing regulatory factors
Busch, A., & Hertel, K. J. (2011) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.100 · Cited by 394 · see citing works
Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex
Zhang, X., Chen, M. H., Wu, X., Kodani, A., Fan, J., Doan, R. N., Ozawa, M., Ma, J., Yoshida, N., Reiter, J. F., et al. (2016) · Cell · doi:10.1016/j.cell.2016.07.025 · Cited by 360 · see citing works
The neurogenetics of alternative splicing
Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.27 · Cited by 340 · see citing works
The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain
Gehman, L. T., Stoilov, P., Maguire, J., Damianov, A., Lin, C.-H., Shiue, L., Ares, M., Mody, I., & Black, D. L. (2011) · Nature Genetics · doi:10.1038/ng.841 · Cited by 331 · see citing works
Splicing-factor alterations in cancers
Anczuków, O., & Krainer, A. R. (2016) · RNA · doi:10.1261/rna.057919.116 · Cited by 297 · see citing works
Novel Insights into NeuN: from Neuronal Marker to Splicing Regulator
Duan, W., Zhang, Y., Hou, Z., Huang, C. L., Zhu, H., Zhang, C., & Yin, Q. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9122-5 · Cited by 296 · see citing works
Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes
Lee, J.-A., Damianov, A., Lin, C.-H., Fontes, M., Parikshak, N. N., Anderson, E. S., Geschwind, D. H., Black, D. L., & Martin, K. C. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.025 · Cited by 232 · see citing works
The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function
Gehman, L. T., Meera, P., Stoilov, P., Shiue, L., O'Brien, J. E., Meisler, M. H., Ares, M., Otis, T. S., & Black, D. L. (2012) · Genes & Development · doi:10.1101/gad.182477.111 · Cited by 213 · see citing works
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development
Fogel, B. L., Wexler, E., Wahnich, A., Friedrich, T., Vijayendran, C., Gao, F., Parikshak, N., Konopka, G., & Geschwind, D. H. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds240 · Cited by 216 · see citing works
Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR
Damianov, A., Yi, Y., Lin, C.-H., Lee, J.-A., Tran, D., Vashisht, A. A., Bahrami‐Samani, E., Xing, Y., Martin, K. C., Wohlschlegel, J. A., et al. (2016) · Cell · doi:10.1016/j.cell.2016.03.040 · Cited by 204 · see citing works
Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens
Feng, J., Wilkinson, M., Liu, X., Purushothaman, I., Ferguson, D., Vialou, V., Maze, I., Shao, N., Kennedy, P., Koo, J., et al. (2014) · Genome Biology · doi:10.1186/gb-2014-15-4-r65 · Cited by 198 · see citing works
Genes and Athletic Performance: An Update
Ahmetov, I. I., Egorova, E. S., Gabdrakhmanova, L. J., & Fedotovskaya, O. N. (2016) · Medicine and sport science/Medicine and sport · doi:10.1159/000445240 · Cited by 183 · see citing works
RNA Protein Interaction in Neurons
Darnell, R. B. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062912-114322 · Cited by 181 · see citing works
Vascular smooth muscle phenotypic diversity and function
Fisher, S. A. (2010) · Physiological Genomics · doi:10.1152/physiolgenomics.00111.2010 · Cited by 178 · see citing works
Bräutigam, C., Rago, L., Rolke, A., Waldmeier, L., Christofori, G., & Winter, J. (2013) · Oncogene · doi:10.1038/onc.2013.50 · Cited by 174 · see citing works
Developmental regulation of RNA processing by Rbfox proteins
Conboy, J. G. (2016) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1398 · Cited by 134 · see citing works
Rbfox2 controls autoregulation in RNA-binding protein networksPreprint
Jangi, M., Boutz, P. L., Paul, P., & Sharp, P. A. (2014) · Genes & Development · doi:10.1101/gad.235770.113 · Cited by 130 · see citing works
RNA-binding proteins in neurological development and disease
Prashad, S., & Gopal, P. P. (2020) · RNA Biology · doi:10.1080/15476286.2020.1809186 · Cited by 119 · see citing works
Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly
Jacko, M., Weyn‐Vanhentenryck, S. M., Smerdon, J. W., Yan, R., Feng, H., Williams, D. J., Pai, J. A., Xu, K., Wichterle, H., & Zhang, C. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.020 · Cited by 126 · see citing works
Dysregulation of mRNA Localization and Translation in Genetic Disease
Wang, E. T., Taliaferro, J. M., Lee, J.-A., Sudhakaran, I. P., Rossoll, W., Groß, C., Moss, K. R., & Bassell, G. J. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.2352-16.2016 · Cited by 115 · see citing works
Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1
Vuong, C. K., Wei, W., Lee, J.-A., Lin, C.-H., Damianov, A., de la Torre-Ubieta, L., Halabi, R., Otis, K. O., Martin, K. C., O’Dell, T. J., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.03.008 · Cited by 102 · see citing works
Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2
Sun, S., Zhang, Z., Fregoso, O. I., & Krainer, A. R. (2011) · RNA · doi:10.1261/rna.030486.111 · Cited by 103 · see citing works
Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma
Lu, Y., Xu, W., Ji, J., Feng, D., Sourbier, C., Yang, Y., Qu, J., Zeng, Z., Wang, C., Chang, X., et al. (2015) · Hepatology · doi:10.1002/hep.27923 · Cited by 101 · see citing works
Dredge, B. K., & Jensen, K. B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021585 · Cited by 99 · see citing works
Microexons: discovery, regulation, and function
Ustianenko, D., Weyn‐Vanhentenryck, S. M., & Zhang, C. (2017) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1418 · Cited by 98 · see citing works
Inference of transcriptional regulation in cancers
Jiang, P., Freedman, M. L., Liu, J. S., & Liu, X. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424272112 · Cited by 93 · see citing works
Orchestration of Neurodevelopmental Programs by RBFOX1
Bill, B. R., Lowe, J. K., DyBuncio, C. T., & Fogel, B. L. (2013) · International Review of Neurobiology · doi:10.1016/b978-0-12-418700-9.00008-3 · Cited by 94 · see citing works
Wei, C., Qiu, J., Zhou, Y., Xue, Y., Hu, J., Ouyang, K., Banerjee, I., Zhang, C., Chen, B., Li, H., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.02.013 · Cited by 92 · see citing works
Dou, X., Xiao, Y., Shen, C., Wang, K., Wu, T., Liu, C., Li, Y., Yu, X., Liu, J., Dai, Q., et al. (2023) · Nature Cell Biology · doi:10.1038/s41556-023-01213-w · Cited by 93 · see citing works
Diversification of the muscle proteome through alternative splicing
Nakka, K. K., Ghigna, C., Gabellini, D., & Dilworth, F. J. (2018) · Skeletal Muscle · doi:10.1186/s13395-018-0152-3 · Cited by 90 · see citing works
RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes
Wei, C., Xiao, R., Chen, L., Cui, H., Zhou, Y., Xue, Y., Hu, J., Zhou, B., Tsutsui, T., Qiu, J., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.04.013 · Cited by 89 · see citing works
Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation
Carreira-Rosario, A., Bhargava, V., Hillebrand, J., Kollipara, R. K., Ramaswami, M., & Buszczak, M. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.02.010 · Cited by 89 · see citing works
Satellite-like cells contribute to pax7-dependent skeletal muscle repair in adult zebrafish
Berberoglu, M. A., Gallagher, T. L., Morrow, Z. T., Talbot, J. C., Hromowyk, K. J., Tenente, I. M., Langenau, D. M., & Amacher, S. L. (2017) · Developmental Biology · doi:10.1016/j.ydbio.2017.03.004 · Cited by 85 · see citing works
Ahmetov, I. I., Kulemin, N. A., Викторович, П. Д., Naumov, V., Akimov, E. B., Bravyy, Y. R., Egorova, E. S., Galeeva, A. R., Generozov, E. V., Kostryukova, E., et al. (2014) · Biology of Sport · doi:10.5604/20831862.1124568 · Cited by 82 · see citing works
RNA ‐binding proteins, neural development and the addictions
Bryant, C. D., & Yazdani, N. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12273 · Cited by 79 · see citing works
RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes
Wei, C., Xiao, R., Chen, L., Cui, H., Zhou, Y., Xue, Y., Hu, J., Zhou, B., Tsutsui, T., Qiu, J., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.06.003 · Cited by 80 · see citing works
Park, J. Y., Li, W., Zheng, D., Zhai, P., Zhao, Y., Matsuda, T., Vatner, S. F., Sadoshima, J., & Tian, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022391 · Cited by 78 · see citing works
Shumay, E., Fowler, J. S., & Volkow, N. D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011067 · Cited by 78 · see citing works
Janakiraman, H., House, R. P., Gangaraju, V. K., Diehl, J. A., Howe, P. H., & Palanisamy, V. (2018) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-17-0547 · Cited by 74 · see citing works
Kuroyanagi, H., Ohno, G., Sakane, H., Maruoka, H., & Hagiwara, M. (2010) · Nature Protocols · doi:10.1038/nprot.2010.107 · Cited by 73 · see citing works
Self-citationRNA binding proteins in the regulation of heart development
Blech-Hermoni, Y. N., & Ladd, A. N. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.08.008 · Cited by 70 · see citing works
Chen, Y., Zubović, L., Yang, F., Godin, K. S., Pavelitz, T., Castellanos, J., Macchi, P., & Varani, G. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw177 · Cited by 65 · see citing works
RNA‐binding proteins in neurodegenerative disease: TDP‐43 and beyond
Hanson, K. A., Kim, S. H., & Tibbetts, R. S. (2011) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.111 · Cited by 65 · see citing works
Huntington’s disease-specific mis-splicing unveils key effector genes and altered splicing factors
Elorza, A., Márquez, Y., Cabrera, J. R., Sanchez‐Trincado, J. L., Santos‐Galindo, M., Hernández, I. H., Picó, S., Díaz‐Hernandéz, J. I., García‐Escudero, R., Irimia, M., et al. (2021) · Brain · doi:10.1093/brain/awab087 · Cited by 58 · see citing works
Decoding muscle alternative splicing
Llorian, M., & Smith, C. W. J. (2011) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2011.03.006 · Cited by 57 · see citing works
Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity
Begg, B. E., Jens, M., Wang, P. Y., Minor, C. M., & Burge, C. B. (2020) · Nature Structural & Molecular Biology · doi:10.1038/s41594-020-0475-8 · Cited by 54 · see citing works
Bozack, A. K., Rifas‐Shiman, S. L., Coull, B. A., Baccarelli, A., Wright, R. O., Amarasiriwardena, C. J., Gold, D. R., Oken, E., Hivert, M., & Cárdenas, A. (2021) · Clinical Epigenetics · doi:10.1186/s13148-021-01198-z · Cited by 54 · see citing works
Runfola, V., Sebastian, S., Dilworth, F. J., & Gabellini, D. (2015) · Journal of Cell Science · doi:10.1242/jcs.161059 · Cited by 54 · see citing works
Maurin, M. M., Ranjouri, M., Megino‐Luque, C., Newberg, J. Y., Du, D., Martin, K., Miner, R. E., Prater, M. S., Wee, D. K. B., Centeno, B. A., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-44126-w · Cited by 53 · see citing works
RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure
Hu, J., Gao, C., Wei, C., Xue, Y., Shao, C., Hao, Y., Gou, L., Zhou, Y., Zhang, J., Ren, S. V., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1822176116 · Cited by 50 · see citing works
Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8A
O'Brien, J. E., Drews, V. L., Jones, J. M., Dugas, J. C., Barres, B. A., & Meisler, M. H. (2012) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2011.10.005 · Cited by 49 · see citing works
Stress Granules Contain Rbfox2 with Cell Cycle-related mRNAs
Park, C., Choi, S., Kim, Y.-E., Lee, S., Park, S.-H., Adelstein, R. S., Kawamoto, S., & Kim, K. K. (2017) · Scientific Reports · doi:10.1038/s41598-017-11651-w · Cited by 49 · see citing works
Kuroyanagi, H., Watanabe, Y., & Hagiwara, M. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003337 · Cited by 46 · see citing works
Self-citationOhno, G., Ono, K., Togo, M., Watanabe, Y., Ono, S., Hagiwara, M., & Kuroyanagi, H. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002991 · Cited by 45 · see citing works
Self-citationThe transcription factor ERG recruits CCR4–NOT to control mRNA decay and mitotic progression
Rambout, X., Detiffe, C., Bruyr, J., Mariavelle, E., Cherkaoui, M., Brohée, S., Demoitié, P., Lebrun, M., Soin, R., Lesage, B., et al. (2016) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3243 · Cited by 45 · see citing works
The function of spliceosome components in open mitosis
Hofmann, J. C., Husedzinovic, A., & Gruß, O. J. (2010) · Nucleus · doi:10.4161/nucl.1.6.13328 · Cited by 44 · see citing works
Maxeiner, S., Glassmann, A., Kao, H., & Schilling, K. (2013) · Histochemistry and Cell Biology · doi:10.1007/s00418-013-1159-9 · Cited by 44 · see citing works
Alternative splicing interference by xenobiotics
Zaharieva, E. E., Chipman, J. K., & Soller, M. (2012) · Toxicology · doi:10.1016/j.tox.2012.01.014 · Cited by 43 · see citing works
RNA splicing regulators play critical roles in neurogenesis
Fisher, E., & Feng, J. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1728 · Cited by 45 · see citing works
Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins
Chen, Y., Yang, F., Zubović, L., Pavelitz, T., Yang, W. J., Godin, K. S., Walker, M. J. P., Zheng, S., Macchi, P., & Varani, G. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2128 · Cited by 43 · see citing works
Zhou, Y., Fan, J., Zhu, H., Li, J., Fan, W., Kapoor, I., Wang, Y., Wang, Y., Zhu, G., & Wang, J. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.09301 · Cited by 43 · see citing works
Cibi, D. M., Mia, M. M., Shekeran, S. G., Yun, L. S., Sandireddy, R., Gupta, P. S., Hota, M., Sun, L., Ghosh, S., & Singh, M. K. (2019) · eLife · doi:10.7554/elife.45418 · Cited by 46 · see citing works
Pistoni, M., Shiue, L., Cline, M., Bortolanza, S., Neguembor, M. V., Xynos, A., Ares, M., & Gabellini, D. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003186 · Cited by 38 · see citing works
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice
Paterson, H. A. B., Yu, S., Artigas, N., Prado, M. A., Haberman, N., Wang, Y.-F., Jobbins, A. M., Pahita, E., Mokochinski, J. B., Hall, Z., et al. (2022) · Nature Metabolism · doi:10.1038/s42255-022-00681-y · Cited by 41 · see citing works
Two Distinct Categories of Focal Deletions in Cancer Genomes
Rajaram, M., Zhang, J., Wang, T., Li, J., Kuscu, C., Qi, H., Kato, M., Grubor, V. D., Weil, R. J., Helland, Å., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066264 · Cited by 41 · see citing works
Evaluation of A2BP1 as an Obesity Gene
Ma, L., Hanson, R. L., Traurig, M. T., Muller, Y. L., Kaur, B. P., Perez, J. M., Meyre, D., Fu, M., Körner, A., Franks, P. W., et al. (2010) · Diabetes · doi:10.2337/db09-1604 · Cited by 41 · see citing works
Parallels between neuron and lens fiber cell structure and molecular regulatory networks
Frederikse, P. H., Kasinathan, C., & Kleiman, N. J. (2012) · Developmental Biology · doi:10.1016/j.ydbio.2012.05.022 · Cited by 38 · see citing works
Jiang, P., Singh, M., & Coller, H. A. (2013) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003075 · Cited by 36 · see citing works
Li, P., Yu, Z., He, L., Zhou, D., Xie, S., Hou, H., & Geng, X. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.05.087 · Cited by 36 · see citing works
Alternative mRNA Splicing in the Pathogenesis of Obesity
Wong, C., Xu, L., & Yau, M. Y. C. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020632 · Cited by 34 · see citing works
RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Kuwasako, K., Takahashi, M., Unzai, S., Tsuda, K., Yoshikawa, S., He, F., Kobayashi, N., Güntert, P., Shirouzu, M., Ito, T., et al. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2870 · Cited by 33 · see citing works
Self-citationLucas, C. G., Calvez, M., Babu, R., & Brown, A. M. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.10.037 · Cited by 33 · see citing works
Shen, F., Xu, X. M., Yu, Z., Li, H., Shen, H., Li, X., Shen, M., & Chen, G. (2020) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x20916860 · Cited by 33 · see citing works
Zubović, L., Baralle, M., & Baralle, F. E. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks249 · Cited by 30 · see citing works
RetractedNlend, R. N., Meyer, K., & Schümperli, D. (2010) · RNA Biology · doi:10.4161/rna.7.4.12206 · Cited by 30 · see citing works
A widespread length-dependent splicing dysregulation in cancer
Zhang, S., Mao, M., Lv, Y., Yang, Y., He, W., Song, Y., Wang, Y., Yang, Y., Abo, M. A., Freedman, J. A., et al. (2022) · Science Advances · doi:10.1126/sciadv.abn9232 · Cited by 26 · see citing works
RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish
Frese, K., Meder, B., Keller, A., Just, S., Haas, J., Vogel, B., Fischer, S., Backes, C., Matzas, M., Köhler, D., et al. (2015) · Journal of Cell Science · doi:10.1242/jcs.166850 · Cited by 27 · see citing works
RNA and neuronal function: the importance of post-transcriptional regulation
Bhat, V. D., Jayaraj, J., & Babu, K. (2022) · Oxford Open Neuroscience · doi:10.1093/oons/kvac011 · Cited by 26 · see citing works
RBFOX2 protein domains and cellular activities
Arya, A. D., Wilson, D. I., Baralle, D., & Raponi, M. (2014) · Biochemical Society Transactions · doi:10.1042/bst20140050 · Cited by 26 · see citing works
Conserved functions of RNA-binding proteins in muscle
Nikonova, E. V., Kao, S.-Y., Ravichandran, K., Wittner, A., & Spletter, M. L. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.02.008 · Cited by 23 · see citing works
Parra, M., Gee, S. L., Mohandas, N., & Conboy, J. G. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.158154 · Cited by 25 · see citing works
Protein kinase WNK3 regulates the neuronal splicing factor Fox-1
Lee, A.-Y., Chen, W., Stippec, S., Self, J., Yang, F., Ding, X., Chen, S., Juang, Y.-C. A., & Cobb, M. H. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215406109 · Cited by 25 · see citing works
Analysis of PI3K pathway components in human cancers
DARAGMEH, J., Barriah, W., Saad, B., & Zaid, H. (2016) · Oncology Letters · doi:10.3892/ol.2016.4309 · Cited by 25 · see citing works
Tissue-specific alternative splicing of Tak1 is conserved in deuterostomes.
Venables, J., Vignal, E., Baghdiguian, S., Fort, P., & Tazi, J. (2012) · Molecular biology and evolution · doi:10.1093/molbev/msr193 · Cited by 24 · see citing works
Amrane, S., Rébora, K., Zniber, I., Dupuy, D., & Mackereth, C. D. (2014) · Nature Communications · doi:10.1038/ncomms5595 · Cited by 23 · see citing works
Su, W., Lv, M., Wang, D., He, Y., Han, H., Zhang, Y., Zhang, X., Lv, S., & Yao, L. (2024) · Mediators of Inflammation · doi:10.1155/2024/7459054 · Cited by 22 · see citing works
RNA-Binding Proteins in Heart Development
Giudice, J., & Cooper, T. A. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-1221-6_11 · Cited by 22 · see citing works
RNA-binding proteins regulating the CD44 alternative splicing
Maltseva, D. V., & Tonevitsky, A. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1326148 · Cited by 21 · see citing works
Hagen, E. M., Sicko, R. J., Kay, D. M., Rigler, S. L., Dimopoulos, A., Ahmad, S., Doleman, M. H., Fan, R., Romitti, P. A., Browne, M. L., et al. (2016) · Human Genetics · doi:10.1007/s00439-016-1727-x · Cited by 21 · see citing works
Chen, P.-F., Hsiao, J. S., Sirois, C. L., & Chamberlain, S. J. (2016) · Scientific Reports · doi:10.1038/srep25368 · Cited by 21 · see citing works
The Role of Genetic Polymorphisms in Diabetic Retinopathy: Narrative Review
Sienkiewicz‐Szłapka, E., Fiedorowicz, E., Król-Grzymała, A., Kordulewska, N. K., Rozmus, D., Cieślińska, A., & Grzybowski, A. E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115865 · Cited by 20 · see citing works
Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq
Schwarzl, T., Sahadevan, S., Lang, B., Miladi, M., Backofen, R., Huber, W. K., Hentze, M. W., & Tartaglia, G. G. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad998 · Cited by 20 · see citing works
MEF2C exon α: Role in gene activation and differentiation
Infantino, V., Convertini, P., Menga, A., & Iacobazzi, V. (2013) · Gene · doi:10.1016/j.gene.2013.08.044 · Cited by 19 · see citing works
Wen, J., Chiba, A., & Cai, X. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq679 · Cited by 19 · see citing works
Kim, Y., Kim, J. O., Park, K.-S., Won, M., Kim, K. E., & Kim, K. K. (2016) · Molecules and Cells · doi:10.14348/molcells.2016.0150 · Cited by 19 · see citing works
Wang, J., Li, G., Yu, D., Wong, Y. P., Yong, T. F., Liang, M. C., Liao, P. H., Foo, R., Hoppe, U. C., & Soong, T. W. (2017) · Channels · doi:10.1080/19336950.2017.1381805 · Cited by 19 · see citing works
The combinatorial control of alternative splicing in C. elegans
Tan, J. H., & Fraser, A. G. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1007033 · Cited by 18 · see citing works
Bitel, C. L., Nathan, R. S., Wong, P., Kuppasani, S., Matsushita, M., Kanazawa, H., & Frederikse, P. H. (2010) · Current Eye Research · doi:10.3109/02713683.2010.500114 · Cited by 18 · see citing works
Hakim, N. H. A., Majlis, B. Y., Suzuki, H., & Tsukahara, T. (2016) · BioScience Trends · doi:10.5582/bst.2016.01169 · Cited by 18 · see citing works
- Authors
- Kuroyanagi, H.
- Affiliations
- Tokyo Medical and Dental University (JP)
- Corresponding author
- Kuroyanagi, Hidehito
- ORCID
- Kuroyanagi, Hidehito
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2009-08-18
- Volume
- 66
- Issue
- 24
- Pages
- 3895-3907
- ISSN
- 1420-682X (ISSN-L)
- 1420-9071
- PMC
- PMC2777236
- OpenAlex
- W2057774013
- Cited by
- 187
- References
- 78
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 12 · 2023: 10 · 2022: 13 · 2021: 7 · 2020: 9 · 2019: 9 · 2018: 12 · 2017: 11 · 2016: 23 · 2015: 10 · 2014: 10 · 2013: 17 · 2012: 11
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- Cellular and Molecular Life Sciences (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Tokyo Medical and Dental University
- Japan Society for the Promotion of Science
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA regulation and disease
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Keywords
- RNA-binding proteins, alternative splicing, intronic splicing enhancer, muscle, heart, brain, splicing regulators, splicing regulatory network, vertebrate genomes
- MeSH terms
- RNA Splicing Factors, Amino Acid Sequence, Animals, Base Sequence, Binding Sites, Humans, Molecular Sequence Data, RNA-Binding Proteins, Spliceosomes, Sequence Homology, Amino Acid, Alternative Splicing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review