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Cited by 130Coffee research and impactsSleep and Work-Related FatigueMind wandering and attention

Effects of caffeine on performance and mood depend on the level of caffeine abstinence

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Yeomans, Martin, Ripley, Tamzin, Davies, Laura, Rusted, Jennifer, Rogers, Peter·2002·Psychopharmacology
DOI 10.1007/s00213-002-1204-1
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Abstract

Rationale Most studies of the effects of caffeine on performance have used regular caffeine consumers who are deprived at test. Thus the reported effects of caffeine could be explained through reversal of caffeine withdrawal.Objectives To test how preloading deprived caffeine consumers with 0, 1 or 2 mg/kg caffeine altered the subsequent ability of caffeine to modify mood and performance.Methods Thirty moderate caffeine consumers were given a drink containing 0, 1 or 2 mg/kg caffeine at breakfast followed 60 min later by a second drink containing either 0 or 1 mg/kg caffeine. Performance on a measure of sustained attention and mood were measured before and after each drink.Results Administration of both 1 and 2 mg/kg caffeine at breakfast decreased reaction time and 1 mg/kg caffeine also increased performance accuracy on the sustained attention (RVIP) task relative to placebo. Both breakfast doses of caffeine also improved rated mental alertness. Similarly, 1 mg/kg caffeine administered 60 min after breakfast decreased reaction time and increased rated mental alertness in the group who had not been given caffeine at breakfast. However, this second dose of caffeine had no effect on subsequent performance or mood in the two groups who had received caffeine at breakfast.Conclusions Caffeine reliably improved performance on a sustained attention task, and increased rated mental alertness, in moderate caffeine consumers who were tested when caffeine-deprived. However, caffeine had no such effects when consumers were no longer caffeine deprived. These data are consistent with the view that reversal of caffeine withdrawal is a major component of the effects of caffeine on mood and performance.

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Crossref · 10.1007/s00213-002-1204-1

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  • The impact of caffeine on performance appears to be greater under conditions that would negatively impact performance, such as acute caffeine withdrawal or sleep deprivation.

    “The impact of caffeine appears to be greater under conditions that would negatively impact performance, such as acute caffeine withdrawal (74–76) or sleep deprivation (71, 77).”

    From The Safety of Ingested Caffeine: A Comprehensive Review (2017) · cites this paper as [75]

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Authors
Yeomans, M., Ripley, T., Davies, L., Rusted, J., & Rogers, P.
Affiliations
  • University of Sussex (GB)
  • University of Bristol (GB)
Corresponding author
Yeomans, Martin
ORCID
Venue
Psychopharmacology
Publisher
Springer Science and Business Media LLC
Published
2002-11-01
Volume
164
Issue
3
Pages
241-249
ISSN
  • 0033-3158 (ISSN-L)
  • 1432-2072
DOI
10.1007/s00213-002-1204-1
OpenAlex
W2151484680
Cited by
130
References
47
Citations by year
2025: 3 · 2024: 4 · 2023: 1 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 4 · 2018: 6 · 2017: 3 · 2016: 6 · 2015: 3 · 2014: 7 · 2013: 6 · 2012: 11
FWCI
5.04
Type
journal article
Language
en
Open access
Licence
Locations
  • Psychopharmacology (publishedVersion)
  • PubMed (publishedVersion)
  • Explore Bristol Research (publishedVersion)
  • Figshare (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Pharmacology › Coffee research and impacts
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
Keywords
caffeine, caffeine withdrawal, caffeine abstinence, sustained attention, reaction time, mental alertness, mood
MeSH terms
Adult, Affect, Central Nervous System Stimulants, Attention, Caffeine, Coffee, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, Humans, Male, Placebos, Psychomotor Performance, Surveys and Questionnaires, Reaction Time, Time Factors

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