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The enigma of vascular cognitive disorder and vascular dementia

Jellinger, Kurt A.·2007·Acta Neuropathologica
DOI 10.1007/s00401-006-0185-2
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Abstract

The prevalence, morphology and pathogenesis of vascular dementia (VaD), recently termed vascular cognitive impairment, are a matter of discussion, and currently used clinical diagnostic criteria show moderate sensitivity (average 50%) and variable specificity (range 64-98%). In Western clinic-based series, VaD is suggested in 8-10% of cognitively impaired aged subjects. Its prevalence in autopsy series varies from 0.03 to 58%, with reasonable values of 8-15%, while in Japan it is seen in 22-35%. Neuropathologic changes associated with cognitive impairment include multifocal and/or diffuse disease and focal lesions: multi-infarct encephalopathy, white matter lesions or arteriosclerotic subcortical (leuko)encephalopathy, multilacunar state, mixed cortico-subcortical type, borderline/watershed lesions, rare granular cortical atrophy, post-ischemic encephalopathy and hippocampal sclerosis. They result from systemic, cardiac and local large or small vessel disease. Recent data indicate that cognitive decline is commonly associated with widespread small ischemic/vascular lesions (microinfarcts, lacunes) throughout the brain with predominant involvement of subcortical and functionally important brain areas. Their pathogenesis is multifactorial, and their pathophysiology affects neuronal networks involved in cognition, memory, behavior and executive functioning. Vascular lesions often coexist with Alzheimer disease (AD) and other pathologies. Minor cerebrovascular lesions, except for…

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Research works printed but not linked: 496

  1. AGS Clinical Practice Committee (2003) Guidelines abstracted from the American Academy of Neurology’s Dementia Guidelines for early detection, diagnosis, and management of dementia. J Am Geriatr Soc 51:869–873 · DOI
  2. Aguero-Torres H, Kivipelto M, von Strauss E (2006) Rethinking the dementia diagnoses in a population-based study: what is Alzheimer’s disease and what is vascular dementia? A study from the Kungsholmen Project. Dement Geriatr Cogn Disord 22:244–249 · DOI
  3. Akatsu H, Takahashi M, Matsukawa N, Ishikawa Y, Kondo N, Sato T, Nakazawa H, Yamada T, Okada H, Yamamoto T, Kosaka K (2002) Subtype analysis of neuropathologically diagnosed patients in a Japanese geriatric hospital. J Neurol Sci 196:63–69 · DOI
  4. Akisaki T, Sakurai T, Takata T, Umegaki H, Araki A, Mizuno S, Tanaka S, Ohashi Y, Iguchi A, Yokono K, Ito H (2006) Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT). Diab Metab Res Rev 22:376–384 · DOI
  5. Ala TA, Beh GO, Frey WH 2nd (2000) Pure hippocampal sclerosis: a rare cause of dementia mimicking Alzheimer’s disease. Neurology 54:843–848 · DOI
  6. Alafuzoff I, Adolfsson R, Grundke-Iqbal I, Winblad B (1985) Perivascular deposits of serum proteins in cerebral cortex in vascular dementia. Acta Neuropathol Berl 66:292–298 · DOI · Paper page
  7. Alix JJ (2006) Recent biochemical advances in white matter ischaemia. Eur Neurol 56:74–77 · DOI
  8. Altieri M, Di Piero V, Pasquini M, Gasparini M, Vanacore N, Vicenzini E, Lenzi GL (2004) Delayed poststroke dementia: a 4-year follow-up study. Neurology 62:2193–2197 · DOI
  9. Alvarez-Sauco M, Molto-Jorda JM, Morera-Guitart J, Frutos-Alegria MT, Matias-Guiu Guia J (2005) [An update on the diagnosis of vascular dementia]. Rev Neurol 41:484–492 · DOI
  10. Amador-Ortiz C, Ahmed Z, Zehr C, Dickson DW (2006) Hippocampal sclerosis in the elderly differs from hippocampal sclerosis in frontal lobe degeneration. Acta Neuropathol (in press) · DOI
  11. Andin U, Gustafson L, Passant U, Brun A (2005) A clinico-pathological study of heart and brain lesions in vascular dementia. Dement Geriatr Cogn Disord 19:222–228 · DOI
  12. Andin U, Gustafson L, Brun A, Passant U (2006) Clinical manifestations in neuropathologically defined subgroups of vascular dementia. Int J Geriatr Psychiatry 21:688–697 · DOI
  13. Appelros P, Samuelsson M, Lindell D (2005) Lacunar infarcts: functional and cognitive outcomes at five years in relation to MRI findings. Cerebrovasc Dis 20:34–40 · DOI
  14. Appelros P, Viitanen M (2005) What causes increased stroke mortality in patients with prestroke dementia? Cerebrovasc Dis 19:323–327 · DOI
  15. Artero S, Tiemeier H, Prins ND, Sabatier R, Breteler MM, Ritchie K (2004) Neuroanatomical localisation and clinical correlates of white matter lesions in the elderly. J Neurol Neurosurg Psychiatry 75:1304–1308 · DOI
  16. Arvanitakis Z, Hachinski V (1999) Vascular cognitive impairment: what else do we need to learn? In: Sisodia S (ed) Alzheimer disease, 2nd edn. Lippincott Williams & Wilkins, Philadelphia, pp 147–160
  17. Attems J, Konig C, Huber M, Lintner F, Jellinger KA (2005) Cause of death in demented and non-demented elderly inpatients; an autopsy study of 308 cases. J Alzheimers Dis 8:57–62 · DOI
  18. Attems J, Jellinger KA (2006) Hippocampal sclerosis in Alzheimer disease and other dementias. Neurology 66:775 · DOI
  19. Awad IA, Johnson PC, Spetzler RF, Hodak JA (1986) Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. II. Postmortem pathological correlations. Stroke 17:1090–1097 · DOI · Paper page
  20. Babikian V, Ropper AH (1987) Binswanger’s disease: a review. Stroke 18:2–12 · DOI
  21. Bacchetta JP, Kovari E, Merlo M, Canuto A, Herrmann FR, Bouras C, Gold G, Hof PR, Giannakopoulos P (2006) Validation of clinical criteria for possible vascular dementia in the oldest-old. Neurobiol Aging. DOI 10.1016/j.neurobiolaging.2006.1002.1006 (in press) · DOI
  22. Bakker FC, Klijn CJM, van der Grond J, Kappelle LJ, Jennekens-Schinkel A (2004) Cognition and quality of life in patients with carotid artery occlusion. A follow-up study. Neurology 62:2230–2235 · DOI
  23. Ballard C, McKeith I, O’Brien J, Kalaria R, Jaros E, Ince P, Perry R (2000) Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes. Dement Geriatr Cogn Disord 11:59–65 · DOI
  24. Ballard CG, Morris CM, Rao H, O’Brien JT, Barber R, Stephens S, Rowan E, Gibson A, Kalaria RN, Kenny RA (2004) APOE epsilon4 and cognitive decline in older stroke patients with early cognitive impairment. Neurology 63:1399–1402 · DOI
  25. Bamford JM, Warlow CP (1988) Evolution and testing of the lacunar hypothesis. Stroke 19:1074–1082 · DOI
  26. Barber R, Gholkar A, Scheltens P, Ballard C, McKeith IG, Morris CM, O’Brien JT (1999) Apolipoprotein E epsilon4 allele, temporal lobe atrophy, and white matter lesions in late-life dementias. Arch Neurol 56:961–965 · DOI
  27. Barber R, Scheltens P, Gholkar A, Ballard C, McKeith I, Ince P, Perry R, O’Brien J (1999) White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer’s disease, vascular dementia, and normal aging. J Neurol Neurosurg Psychiatry 67:66–72 · DOI
  28. Barker WW, Luis CA, Kashuba A, Luis M, Harwood DG, Loewenstein D, Waters C, Jimison P, Shepherd E, Sevush S, Graff-Radford N, Newland D, Todd M, Miller B, Gold M, Heilman K, Doty L, Goodman I, Robinson B, Pearl G, Dickson D, Duara R (2002) Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank. Alzheimer Dis Assoc Disord 16:203–212 · DOI
  29. Barkhof F, Scheltens P (2002) Imaging of white matter lesions. Cerebrovasc Dis 13(Suppl 2):21–30 · DOI
  30. Barret AM (1913) Presenile, arteriosclerotic and senile disorders of the brain and cord. In: White WA, Jellife SA (eds) The modern treatment of nervous and mental diseases. Kimpton, London, pp 675–709 · DOI
  31. Bartzokis G, Cummings JL, Sultzer D, Henderson VW, Nuechterlein KH, Mintz J (2003) White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. Arch Neurol 60:393–398 · DOI
  32. Basso A, Capitani E, Luzzatti C, Spinnler H (1981) Intelligence and left hemisphere disease. The role of aphasia, apraxia and size of lesion. Brain 104:721–734 · DOI
  33. Beach TG, Sue L, Scott S, Layne K, Newell A, Walker D, Baker M, Sahara N, Yen SH, Hutton M, Caselli R, Adler C, Connor D, Sabbagh M (2003) Hippocampal sclerosis dementia with tauopathy. Brain Pathol 13:263–278 · DOI
  34. Beach TG, Wilson JR, Sue LI, Newell A, Poston M, Cisneros R, Pandya Y, Esh C, Connor DJ, Sabbagh M, Walker DG, Roher AB (2007): Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles. Acta Neuropathol (Brl) 113:13–21 · DOI
  35. Bennett DA, Wilson RS, Gilley DW, Fox JH (1990) Clinical diagnosis of Binswanger’s disease. J Neurol Neurosurg Psychiatry 53:961–965 · DOI
  36. Benson MD (1996) Leptomeningeal amyloid and variant transthyretins. Am J Pathol 148:351–354
  37. Berg L, McKeel DW Jr, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM, Price JL, Gearing M, Mirra SS, Saunders AM (1998) Clinicopathologic studies in cognitively healthy aging and Alzheimer’s disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype. Arch Neurol 55:326–335 · DOI · Paper page
  38. Bhatia KP, Marsden CD (1994) The behavioural and motor consequences of focal lesions of the basal ganglia in man. Brain 117:859–876 · DOI
  39. Blass JP, Hoyer S, Nitsch R (1991) A translation of Otto Binswanger’s article, ‘The delineation of the generalized progressive paralyses’. 1894. Arch Neurol 48:961–972 · DOI
  40. Blevins G, Macaulay R, Harder S, Fladeland D, Yamashita T, Yazaki M, Hamidi Asl K, Benson MD, Donat JR (2003) Oculoleptomeningeal amyloidosis in a large kindred with a new transthyretin variant Tyr69His. Neurology 60:1625–1630 · DOI
  41. Boiten J, Lodder J (2002) Risk factors for lacunar stroke. In: Donnan GA, Norrving B, Bogousslavski J (eds) Subcortical stroke. Oxford University Press, Oxford, pp 87–97 · DOI
  42. Bokura H, Kobayashi S, Yamaguchi S (1998) Distinguishing silent lacunar infarction from enlarged Virchow–Robin spaces: a magnetic resonance imaging and pathological study. J Neurol 245:116–122 · DOI · Paper page
  43. Bouras C, Kovari E, Herrmann FR, Rivara CB, Bailey TL, von Gunten A, Hof PR, Giannakopoulos P (2006) Stereologic analysis of microvascular morphology in the elderly: Alzheimer disease pathology and cognitive status. J Neuropathol Exp Neurol 65:235–244 · DOI
  44. Bowler J (2003) Epidemiology: identifying vascular cognitive impairment. Int Psychogeriatr 15(Suppl 1):115–122 · DOI
  45. Bowler JV, Hachinski V (1995) Vascular cognitive impairment: a new approach to vascular dementia. In: Hachinski V (ed) Baillière’s clinical neurology. Cerebrovascular disease. Baillière Tindall, London, pp 357–376
  46. Bowler JV, Hachinski V (1995) Vascular cognitive impairment: a new approach to vascular dementia. Baillieres Clin Neurol 4:357–376
  47. Bowler JV, Hachinski V (eds) (2003) Vascular cognitive impairment. Preventable dementia. Oxford University Press, Oxford · DOI
  48. Bowler JV, Hachinski V (2003) Current criteria for vascular dementia—a critical appraisal. In: Bowler JV, Hachinski V (eds) Vascular cognitive impairment. Preventable dementia. Oxford University Press, Oxford, pp 1–11 · DOI
  49. Bowler JV (2005) Vascular cognitive impairment. J Neurol Neurosurg Psychiatry 76(Suppl 5):35–44 · DOI
  50. Bracco L, Campani D, Baratti E, Lippi A, Inzitari D, Pracucci G, Amaducci L (1993) Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: a longitudinal study. J Neurol Sci 120:131–136 · DOI
  51. Bracco L, Piccini C, Moretti M, Mascalchi M, Sforza A, Nacmias B, Cellini E, Bagnoli S, Sorbi S (2005) Alzheimer’s disease: role of size and location of white matter changes in determining cognitive deficits. Dement Geriatr Cogn Disord 20:358–366 · DOI
  52. Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW (1988) Brain MR: pathologic correlation with gross and histopathology. 1. Lacunar infarction and Virchow–Robin spaces. AJR Am J Roentgenol 151:551–558 · DOI
  53. Breteler MM, van Swieten JC, Bots ML, Grobbee DE, Claus JJ, van den Hout JH, van Harskamp F, Tanghe HL, de Jong PT, van Gijn J et al (1994) Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study. Neurology 44:1246–1252 · DOI
  54. Brion S, Pragier G, Guerin R, Teitgen M (1969) Syndrome de Korsakoff par ramollisement bilatéral du fornix. Rev Neurol 120:255–262
  55. Brown MM, Pelz DM, Hachinski VC (1990) White matter vasodilatory reserve is impaired in patients with cerebrovascular disease and diffuse periventricular lacunes. J Neurol 237:157
  56. Brown WR, Moody DM, Thore CR, Challa VR (2000) Cerebrovascular pathology in Alzheimer’s disease and leukoaraiosis. Ann N Y Acad Sci 903:39–45 · DOI
  57. Brown WR, Moody DM, Challa VR, Thore CR, Anstrom JA (2002) Venous collagenosis and arteriolar tortuosity in leukoaraiosis. J Neurol Sci 203–204:159–163 · DOI
  58. Brun A, Englund E (1986) A white matter disorder in dementia of the Alzheimer type: a pathoanatomical study. Ann Neurol 19:253–262 · DOI · Paper page
  59. Brun A, Fredriksson K, Gustafson L (1992) Pure subcortical arteriosclerotic encephalopathy (Binswanger’s disease): a clinicopathological study. Part I: pathological features. Cerebrovasc Dis 2:87–92 · DOI
  60. Brun A (1994) Pathology and pathophysiology of cerebrovascular dementia: pure subgroups of obstructive and hypoperfusive etiology. Dementia 5:145–147
  61. Burton E, Ballard C, Stephens S, Kenny RA, Kalaria R, Barber R, O’Brien J (2003) Hyperintensities and fronto-subcortical atrophy on MRI are substrates of mild cognitive deficits after stroke. Dement Geriatr Cogn Disord 16:113–118 · DOI
  62. Cabrejo L, Chassagne P, Doucet J, Laquerriere A, Puech N, Hannequin D (2006) Sporadic cerebral amyloidotic angiopathy. Rev Neurol (Paris) 162:1059–1067 · DOI
  63. Cadavid D, Mena H, Koeller K, Frommelt RA (2000) Cerebral beta amyloid angiopathy is a risk factor for cerebral ischemic infarction. A case control study in human brain biopsies. J Neuropathol Exp Neurol 59:768–773 · DOI
  64. Cannata AP, Alberoni M, Franceschi M, Mariani C (2002) Frontal impairment in subcortical ischemic vascular dementia in comparison to Alzheimer’s disease. Dement Geriatr Cogn Disord 13:101–111 · DOI
  65. Capizzano AA, Acion L, Bekinschtein T, Furman M, Gomila H, Martinez A, Mizrahi R, Starkstein SE (2004) White matter hyperintensities are significantly associated with cortical atrophy in Alzheimer’s disease. J Neurol Neurosurg Psychiatry 75:822–827 · DOI
  66. Caplan LR (1995) Binswanger’s disease—revisited. Neurology 45:626–633 · DOI
  67. Caplan LR, Helgason CM (1995) Caudate infarcts. In: Bogousslavsky J (ed) Lacunar and other subcortical infarctions. Oxford University Press, Oxford, pp 117–130
  68. Caplan LR (2002) Caudate infarcts. In: Bogousslavsky J (ed) Subcortical stroke, 2nd edn. Oxford University Press, Oxford, pp 208–223
  69. Castaigne P, Lhermitte F, Buge A, Escourolle R, Hauw JJ, Lyon-Caen O (1981) Paramedian thalamic and midbrain infarct: clinical and neuropathological study. Ann Neurol 10:127–148 · DOI
  70. Chabriat H, Bousser MG (2002) Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. In: Bogousslavsky J (ed) Subcortical stroke, 2nd edn. Oxford University Press, Oxford, pp 116–126
  71. Challa VR, Thore CR, Moody DM, Anstrom JA, Brown WR (2004) Increase of white matter string vessels in Alzheimer’s disease. J Alzheimers Dis 6:379–383 · DOI
  72. Chen YF, Wang H, Chu Y, Huang YC, Su MY (2006) Regional quantification of white matter hyperintensity in normal aging, mild cognitive impairment, and Alzheimer’s disease. Dement Geriatr Cogn Disord 22:177–184 · DOI
  73. Chen YW, Gurol ME, Rosand J, Viswanathan A, Rakich SM, Groover TR, Greenberg SM, Smith EE (2006) Progression of white matter lesions and hemorrhages in cerebral amyloid angiopathy. Neurology 67:83–87 · DOI
  74. Chiu HF, Lam LC, Chi I, Leung T, Li SW, Law WT, Chung DW, Fung HH, Kan PS, Lum CM, Ng J, Lau J (1998) Prevalence of dementia in Chinese elderly in Hong Kong. Neurology 50:1002–1009 · DOI
  75. Cho KO, La HO, Cho YJ, Sung KW, Kim SY (2006) Minocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusion. J Neurosci Res 83:285–291 · DOI
  76. Christiansen P, Larsson HB, Thomsen C, Wieslander SB, Henriksen O (1994) Age dependent white matter lesions and brain volume changes in healthy volunteers. Acta Radiol 35:117–122 · DOI
  77. Chui HC, Victoroff JI, Margolin D, Jagust W, Shankle R, Katzman R (1992) Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer’s Disease Diagnostic and Treatment Centers. Neurology 42:473–480 · DOI · Paper page
  78. Chui HC, Mack W, Jackson JE, Mungas D, Reed BR, Tinklenberg J, Chang FL, Skinner K, Tasaki C, Jagust WJ (2000) Clinical criteria for the diagnosis of vascular dementia: a multicenter study of comparability and interrater reliability. Arch Neurol 57:191–196 · DOI
  79. Chui HC (2006) Vascular cognitive impairment: today and tomorrow. Alzheimer’s Dement 2:185–194 · DOI · Paper page
  80. Chukwudelunzu FE, Meschia JF, Graff-Radford NR, Lucas JA (2001) Extensive metabolic and neuropsychological abnormalities associated with discrete infarction of the genu of the internal capsule. J Neurol Neurosurg Psychiatry 71:658–662 · DOI
  81. Cole FM, Yates PO (1968) Comparative incidence of cerebrovascular lesions in normotensive and hypertensive patients. Neurology 18:255–259 · DOI
  82. Cook IA, Leuchter AF, Morgan ML, Dunkin JJ, Witte E, David S, Mickes L, O’Hara R, Simon S, Lufkin R, Abrams M, Rosenberg S (2004) Longitudinal progression of subclinical structural brain disease in normal aging. Am J Geriatr Psychiatry 12:190–200 · DOI
  83. Corbett A, Bennett H, Kos S (1994) Cognitive dysfunction following subcortical infarction. Arch Neurol 51:999–1007 · DOI
  84. Corey-Bloom J, Sabbagh MN, Bondi MW, Hansen L, Alford MF, Masliah E, Thal LJ (1997) Hippocampal sclerosis contributes to dementia in the elderly. Neurology 48:154–160 · DOI
  85. Cosentino SA, Jefferson AL, Carey M, Price CC, Davis-Garrett K, Swenson R, Libon DJ (2004) The clinical diagnosis of vascular dementia: A comparison among four classification systems and a proposal for a new paradigm. Clin Neuropsychol 18:6–21 · DOI
  86. Coulthard A, Blank SC, Bushby K, Kalaria RN, Burn DJ (2000) Distribution of cranial MRI abnormalities in patients with symptomatic and subclinical CADASIL. Br J Radiol 73:256–265 · DOI · Paper page
  87. Crystal H, Dickson D (2002) Cerebral infarcts in patients with autopsy proven Alzheimer’s disease (Abstract). Neurobiol Aging 23:207
  88. Cullen KM, Kócsi Z, Stone J (2006) Microvascular pathology in the aging human brain: Evidence that senile plaques are sites of microhaemorrhages. Neurobiol Aging 27:1786–1796 · DOI
  89. Cummings JL, Benson DF (1988) Psychological dysfunction accompanying subcortical dementias. Annu Rev Med 39:53–61 · DOI
  90. Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neurol 50:873–880 · DOI · Paper page
  91. D’Abreu A, Ott BR (2005) Poststroke dementia. In: Paul RH, Cohen R, Ott BR, Salloway S (eds) Vascular dementia: cerebrovascular mechanisms and clinical management. Human Press Inc. Totowa, pp 231–241 · DOI
  92. de Freitas GR, Bogousslavsky J (2002) Thalamic infarcts. In: Bogousslavsky J (ed) Subcortical stroke, 2nd edn. Oxford University Press, Oxford, pp 255–285 · DOI
  93. de Groot JC, de Leeuw FE, Oudkerk M, van Gijn J, Hofman A, Jolles J, Breteler MM (2000) Cerebral white matter lesions and cognitive function: the Rotterdam Scan Study. Ann Neurol 47:145–151 · DOI
  94. de Groot JC, de Leeuw FE, Oudkerk M, van Gijn J, Hofman A, Jolles J, Breteler MM (2002) Periventricular cerebral white matter lesions predict rate of cognitive decline. Ann Neurol 52:335–341 · DOI
  95. de Leeuw FE, de Groot JC, Oudkerk M, Witteman JC, Hofman A, van Gijn J, Breteler MM (2002) Hypertension and cerebral white matter lesions in a prospective cohort study. Brain 125:765–772 · DOI · Paper page
  96. de Leeuw FE, Korf E, Barkhof F, Scheltens P (2006) White matter lesions are associated with progression of medial temporal lobe atrophy in Alzheimer disease. Stroke 37:2248–2252 · DOI
  97. de Mendonca A, Ribeiro F, Guerreiro M, Palma T, Garcia C (2005) Clinical significance of subcortical vascular disease in patients with mild cognitive impairment. Eur J Neurol 12:125–130 · DOI
  98. de Reuck J, Schaumburg HH (1972) Periventricular atherosclerotic leukoencephalopathy. Neurology 22:1094–1097 · DOI
  99. de Reuck J, Van der Eecken H (1976) The topography of infarcts in the lacunar state. In: Reivich M (ed) Cerebral vascular disease, vol 7. Thieme Stuttgart, pp 162–165
  100. de Reuck J, Sieben G, de Coster W, vander Eecken H (1982) Dementia and confusional state in patients with cerebral infarcts. A clinicopathological study. Eur Neurol 21:94–97 · DOI
  101. de Reuck J, de Reus R, de Koninck J (1987) Sneddon’s syndrome A not unusual cause of stroke in young women. In: Ott E (ed) Cerebral vascular disease. Excerpta medica, vol 6, Amsterdam, pp 171–174
  102. de Reuck J (1994) Neuropathology of vascular dementia. In: Scheltens P (ed) Current issues in neurodegenerative diseases, vol 6: vascular dementia. ICG Amsterdam, pp 9–15
  103. DeCarli C, Miller BL, Swan GE, Reed T, Wolf PA, Carmelli D (2001) Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study. Arch Neurol 58:643–647 · DOI
  104. del Ser T, Bermejo F, Portera A, Arredondo JM, Bouras C, Constantinidis J (1990) Vascular dementia. A clinicopathological study. J Neurol Sci 96:1–17 · DOI
  105. Derouesne C, Gray F, Escourelle R, Castaigne P (1987) ‘Expanding cerebral lacunae’ in a hypertensive patient with normal pressure hydrocephalus. Neuropathol Appl Neurobiol 13:309–320 · DOI
  106. Derouesne C, Poirier J (1999) [Cerebral lacunae: still under debate]. Rev Neurol Paris 155:823–831
  107. Derouesne C (2005) Vascular dementia: the dubious disease (French). Psychol Neuropsychiatr Vieil 3:89–96
  108. Desmond DW (1996) Vascular dementia: a construct in evolution. Cerebrovasc Brain Metab Rev 8:296–325
  109. Desmond DW, Moroney JT, Sano M, Stern Y (2002) Incidence of dementia after ischemic stroke: results of a longitudinal study. Stroke 33:2254–2260 · DOI
  110. Dichgans M, Mayer M, Uttner I, Bruning R, Muller-Hocker J, Rungger G, Ebke M, Klockgether T, Gasser T (1998) The phenotypic spectrum of CADASIL: clinical findings in 102 cases. Ann Neurol 44:731–739 · DOI
  111. Dickson DW, Davies P, Bevona C, Van Hoeven KH, Factor SM, Grober E, Aronson MK, Crystal HA (1994) Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans. Acta Neuropathol (Berl) 88:212–221 · DOI
  112. Dickson DW (2001) Neuropathology of Alzheimer’s disease and other dementias. Clin Geriatr Med 17:209–228 · DOI
  113. Doody RS, Azher SN, Haykal HA, Dunn JK, Liao T, Schneider L (2000) Does APO epsilon4 correlate with MRI changes in Alzheimer’s disease? J Neurol Neurosurg Psychiatry 69:668–671 · DOI
  114. Du AT, Schuff N, Laakso MP, Zhu XP, Jagust WJ, Yaffe K, Kramer JH, Miller BL, Reed BR, Norman D, Chui HC, Weiner MW (2002) Effects of subcortical ischemic vascular dementia and AD on entorhinal cortex and hippocampus. Neurology 58:1635–1641 · DOI
  115. Du A-T, Schuff N, Chao LL, Kornak J, Ezekiel F, Jagust WJ, Kramer JH, Reed BR, Miller BL, Norman D, Chui HC, Weiner MW (2005) White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy. Neurobiol Aging 26:553–559 · DOI
  116. Dupont S (2003) [The anatomy of episodic memory: evolution of concepts]. Morphologie 87:5–9
  117. Duyckaerts C, Delaere P, Hauw JJ, Abbamondi-Pinto AL, Sorbi S, Allen I, Brion JP, Flament-Durand J, Duchen L, Kauss J et al (1990) Rating of the lesions in senile dementia of the Alzheimer type: concordance between laboratories. A European multicenter study under the auspices of EURAGE. J Neurol Sci 97:295–323 · DOI
  118. Duyckaerts C, Dickson DW (2003) Neuropathology of Alzheimer´s disease. In: Dickson DW (ed) Neurodegeneration. The molecular pathology of dementia and movement disorders. ISN Neuropath Press, Basel, pp 47–65
  119. Englund E (2000) White matter pathology in vascular dementia. In: Folstein M (ed) Cerebrovascular disease and dementia. pathology, neuropsychiatry and management. Martin Dunitz Publ, London, pp 77–84
  120. Englund E (2002) Neuropathology of white matter lesions in vascular cognitive impairment. Cerebrovasc Dis 13(Suppl 2):11–15 · DOI
  121. Enzinger C, Smith S, Fazekas F, Drevin G, Ropele S, Nichols T, Behrens T, Schmidt R, Matthews PM (2006) Lesion probability maps of white matter hyperintensities in elderly individuals: results of the Austrian stroke prevention study. J Neurol 253:1064–1070 · DOI
  122. Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A (1988) Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study. J Neurol Neurosurg Psychiatry 51:1037–1044 · DOI
  123. Erkinjuntti T, Benavente O, Eliasziw M, Munoz DG, Sulkava R, Haltia M, Hachinski V (1996) Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementia. Arch Neurol 53:325–332 · DOI
  124. Erkinjuntti T (1999) Cerebrovascular dementia: pathophysiology, diagnosis and treatment. CNS Drugs 12:35–48 · DOI
  125. Erkinjuntti T (2000) Classification and criteria. In: Folstein M (ed) Cerebrovascular disease and dementia. Pathology, neuropsychiatry and management. Martin Dunitz Publ, London, pp 99–113
  126. Erkinjuntti T, Inzitari D, Pantoni L, Wallin A, Scheltens P, Rockwood K, Roman GC, Chui H, Desmond DW (2000) Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 59:23–30
  127. Erkinjuntti T (2002) Subcortical vascular dementia. Cerebrovasc Dis 13(Suppl 2):58–60 · DOI
  128. Esiri MM, Wilcock GK (1986) Cerebral amyloid angiopathy in dementia and old age. J Neurol Neurosurg Psychiatry 49:1221–1226 · DOI
  129. Esiri MM, Hyman BT, Beyreuther K, Masters CL (1997) Vascular dementia. In: Lantos P (ed) Greenfield’s neuropathology, 6th edn. Arnold Publishing, London, pp 204–210
  130. Esiri MM (2000) Which vascular lesions are of importance in vascular dementia? Ann N Y Acad Sci 903:239–243 · DOI
  131. Farkas E, Donka G, De Vos RA, Mihaly A, Bari F, Luiten PG (2004) Experimental cerebral hypoperfusion induces white matter injury and microglial activation in the rat brain. Acta Neuropathol (Berl) 108:57–64 · DOI
  132. Farkas E, de Vos RA, Donka G, Jansen Steur EN, Mihaly A, Luiten PG (2006) Age-related microvascular degeneration in the human cerebral periventricular white matter. Acta Neuropathol (Berl) 111:150–157 · DOI
  133. Farkas E, Luiten PG (2007) Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative disease. Brain Res (in press) · DOI
  134. Fayet G, Hauw JJ, Delaere P, He Y, Duyckaerts C, Beck H, Forette F, Gallinari C, Laurent M, Moulias R et al (1994) Neuropathology of 20 centenarians. I: Clinical data. Rev Neurol 150:16–21
  135. Fazekas F, Schmidt R, Kleinert R, Kapeller P, Roob G, Flooh E (1998) The spectrum of age-associated brain abnormalities: their measurement and histopathological correlates. J Neural Transm Suppl 53:31–39 · DOI
  136. Feigin L, Poport N (1963) Neuropathological changes late in cerebral edema. The relationship to trauma, hypertensive disease and Binswanger’s encephalopathy. J Neuropathol Exp Neurol 22:500–511 · DOI
  137. Fein G, Di Sclafani V, Tanabe J, Cardenas V, Weiner MW, Jagust WJ, Reed BR, Norman D, Schuff N, Kusdra L, Greenfield T, Chui H (2000) Hippocampal and cortical atrophy predict dementia in subcortical ischemic vascular disease. Neurology 55:1626–1635 · DOI
  138. Ferguson SC, Blane A, Perros P, McCrimmon RJ, Best JJ, Wardlaw J, Deary IJ, Frier BM (2003) Cognitive ability and brain structure in type 1 diabetes: relation to microangiopathy and preceding severe hypoglycemia. Diabetes 52:149–156 · DOI
  139. Fernando MS, Ince PG (2004) Vascular pathologies and cognition in a population-based cohort of elderly people. J Neurol Sci 226:13–17 · DOI · Paper page
  140. Fernando MS, O’Brien JT, Perry RH, English P, Forster G, McMeekin W, Slade JY, Golkhar A, Matthews FE, Barber R, Kalaria RN, Ince PG (2004) Comparison of the pathology of cerebral white matter with post-mortem magnetic resonance imaging (MRI) in the elderly brain. Neuropathol Appl Neurobiol 30:385–395 · DOI
  141. Ferrand J (1902) Essai sur l’hémiplégie des viellards. Les lacunes de désintégration cérébrale. Thesis, Rousset, Paris
  142. Ferrer I, Bella R, Serrano MT, Marti E, Guionnet N (1990) Arteriolosclerotic leucoencephalopathy in the elderly and its relation to white matter lesions in Binswanger’s disease, multi-infarct encephalopathy and Alzheimer’s disease. J Neurol Sci 98:37–50 · DOI
  143. Filley CM, Thompson LL, Sze CI, Simon JA, Paskavitz JF, Kleinschmidt-DeMasters BK (1999) White matter dementia in CADASIL. J Neurol Sci 163:163–167 · DOI
  144. Firbank MJ, Minett T, O’Brien JT (2003) Changes in DWI and MRS associated with white matter hyperintensities in elderly subjects. Neurology 61:950–954 · DOI
  145. Fischer P, Lassmann H, Jellinger K, Simanyi M, Bancher C, Travniczek-Marterer A, Gatterer G, Danielczyk W (1991) [Alzheimer dementia. A clinical long-term study with quantitative neuropathology]. Wien Med Wochenschr 141:455–462
  146. Fisher CM (1965) The vascular lesion in lacunae. Trans Am Neurol Assoc 90:243–245
  147. Fisher CM (1968) Dementia in cerebral vascular disease. In: Whisnant J (ed) Cerebral vascular disease. Sixth Princeton Conference. Greene and Stratton, New York, pp 232–236
  148. Fisher CM (1982) Lacunar strokes and infarcts: a review. Neurology 32:871–876 · DOI · Paper page
  149. Fisher CM (1989) Binswanger’s encephalopathy: a review. J Neurol 236:65–79 · DOI
  150. Fratiglioni L, Grut M, Forsell Y, Viitanen M, Grafstrom M, Holmen K, Ericsson K, Backman L, Ahlbom A, Winblad B (1991) Prevalence of Alzheimer’s disease and other dementias in an elderly urban population: relationship with age, sex, and education. Neurology 41:1886–1892 · DOI · Paper page
  151. Galasko D, Hansen LA, Katzman R, Wiederholt W, Masliah E, Terry R, Hill LR, Lessin P, Thal LJ (1994) Clinical–neuropathological correlations in Alzheimer’s disease and related dementias. Arch Neurol 51:888–895 · DOI
  152. Gamaldo A, Moghekar A, Kilada S, Resnick SM, Zonderman AB, O’Brien R (2006) Effect of a clinical stroke on the risk of dementia in a prospective cohort. Neurology 67:1363–1369 · DOI
  153. Garcia JH, Brown GG (1992) Vascular dementia: neuropathologic alterations and metabolic brain changes. J Neurol Sci 109:121–131 · DOI
  154. Garcia JH, Lassen NA, Weiller C, Sperling B, Nakagawa J (1995) Ischemic stroke and incomplete infarction. Stroke 27:761–765 · DOI
  155. Garde E, Mortensen EL, Krabbe K, Rostrup E, Larsson HB (2000) Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study. Lancet 356:628–634 · DOI · Paper page
  156. Garde E, Lykke Mortensen E, Rostrup E, Paulson OB (2005) Decline in intelligence is associated with progression in white matter hyperintensity volume. J Neurol Neurosurg Psychiatry 76:1289–1291 · DOI · Paper page
  157. Gertz HJ, Wolf H, Arendt T (2002) [Vascular dementia]. Nervenarzt 73:393–404 · DOI
  158. Geschwind N (1965) Disconnexion syndromes in animals and man. I. Brain 88:237–294 · DOI
  159. Giannakopoulos P, Hof PR, Surini M, Michel JP, Bouras C (1993) Quantitative immunohistochemical analysis of the distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of nonagenarians and centenarians. Acta Neuropathol 85:602–610 · DOI
  160. Giannakopoulos P, Hof PR, Michel JP, Guimon J, Bouras C (1997) Cerebral cortex pathology in aging and Alzheimer’s disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts. Brain Res Brain Res Rev 25:217–245 · DOI
  161. Giannakopoulos P, Gold G, Kövari E, von Gunten A, Imhof A, Bouras C, Hof PR (2007) Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience. Acta Neuropathol 113:1–12 · DOI
  162. Glees P, Griffith GH (1953) Bilateral destruction of the hippocampus in case of dementia. Monatsschr Psychiatr Neurol 123:193–204 · DOI
  163. Gold G, Giannakopoulos P, Montes-Paixao Junior C, Herrmann FR, Mulligan R, Michel JP, Bouras C (1997) Sensitivity and specificity of newly proposed clinical criteria for possible vascular dementia. Neurology 49:690–694 · DOI
  164. Gold G, Bouras C, Canuto A, Bergallo MF, Herrmann FR, Hof PR, Mayor PA, Michel JP, Giannakopoulos P (2002) Clinicopathological validation study of four sets of clinical criteria for vascular dementia. Am J Psychiatry 159:82–87 · DOI · Paper page
  165. Gold G, Kovari E, Herrmann FR, Canuto A, Hof PR, Michel JP, Bouras C, Giannakopoulos P (2005) Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia. Stroke 36:1184–1188 · DOI
  166. Gorelick PB (1997) Status of risk factors for dementia associated with stroke. Stroke 28:459–463 · DOI
  167. Goulding J, Signorini D, Chatterjee S, Nicoll J, Stewart J, Morris R, Lammie G (1999) Inverse relation between Braak stage and cerebrovascular pathology in Alzheimer predominant dementia. J Neurol Neurosurg Psychiatry 67:654–657 · DOI
  168. Grabowski TJ, Cho HS, Vonsattel JP, Rebeck GW, Greenberg SM (2001) Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy. Ann Neurol 49:697–705 · DOI · Paper page
  169. Grafton ST, Sumi SM, Stimac GK, Alvord EC Jr, Shaw CM, Nochlin D (1991) Comparison of postmortem magnetic resonance imaging and neuropathologic findings in the cerebral white matter. Arch Neurol 48:293–298 · DOI
  170. Gray F, Dubas F, Roullet E, Escourolle R (1985) Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy. Ann Neurol 18:54–59 · DOI
  171. Greenberg SM, Gurol ME, Rosand J, Smith EE (2004) Amyloid angiopathy-related vascular cognitive impairment. Stroke 35:2616–2619 · DOI · Paper page
  172. Gunning-Dixon FM, Raz N (2003) Neuroanatomical correlates of selected executive functions in middle-aged and older adults: a prospective MRI study. Neuropsychologia 41:1929–1941 · DOI
  173. Gustafson I, Passant U (2000) Clinical pathological correlates. In: Folstein M (ed) Cerebrovascular disease and dementia. Pathology, neuropsychiatry and management. Martin Dunitz Publ, London, pp 85–97
  174. Hachinski V (2006) Commentary on “Vascular cognitive impairment: today and tomorrow.” Vascular cognitive impairment: yesterday, today, and tomorrow. Alzheimers Dement 2:198–199 · DOI
  175. Hachinski VC, Lassen NA, Marshall J (1974) Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet 2:207–210 · DOI · Paper page
  176. Hachinski VC, Iliff L, Zihlka E, Du Boulay G, McAllister V, Marshall J, Russel R, Symon L (1975) Cerebral blood flow in dementia. Arch Neurol 32:632–637 · DOI · Paper page
  177. Hachinski VC, Potter P, Merskey H (1987) Leuko-araiosis. Arch Neurol 44:21–23 · DOI · Paper page
  178. Haglund M, Sjobeck M, Englund E (2004) Severe cerebral amyloid angiopathy characterizes an underestimated variant of vascular dementia. Dement Geriatr Cogn Disord 18:132–137 · DOI
  179. Haglund M, Passant U, Sjobeck M, Ghebremedhin E, Englund E (2006) Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia. Int J Geriatr Psychiatry 21:681–687 · DOI
  180. Halliday G, Ng T, Rodriguez M, Harding A, Blumbergs P, Evans W, Fabian V, Fryer J, Gonzales M, Harper C, Kalnins R, Masters CL, McLean C, Milder DG, Pamphlett R, Scott G, Tannenberg A, Kril J (2002) Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria. Acta Neuropathol (Berl) 104:72–78 · DOI · Paper page
  181. Haltia M, Ghiso J, Prelli F, Gallo G, Kiuru S, Somer H, Palo J, Frangione B (1990) Amyloid in familial amyloidosis, Finnish type, is antigenically and structurally related to gelsolin. Am J Pathol 136:1223–1228
  182. Hamel E (2004) Cholinergic modulation of the cortical microvascular bed. Prog Brain Res 145:171–178 · DOI
  183. Hanyu H, Tanaka Y, Shimizu S, Takasaki M, Fujita H, Kaneko N, Yamamoto Y, Harada M (2003) Cerebral microbleeds in Binswanger’s disease: a gradient-echo T2*-weighted magnetic resonance imaging study. Neurosci Lett 340:213–216 · DOI
  184. Hasegawa K, Homma A, Imai Y (1986) An epidemiological study of age-related dementia in the community. Int J Geriatr Psychiatry 1:94–105 · DOI
  185. Hatanpaa KJ, Blass DM, Pletnikova O, Crain BJ, Bigio EH, Hedreen JC, White CL 3rd, Troncoso JC (2004) Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia. Neurology 63:538–542 · DOI · Paper page
  186. Hauw JJ, Zekry D, Seilhean D, Forette B, Gallinari C, Laurent M, Moulias R, Piette F, Sachet A, Duyckaerts C (2002) Neuropathology of the cerebral vessels in centenarians. J Mal Vasc 27:S13–S18.
  187. Hebert R, Brayne C (1995) Epidemiology of vascular dementia. Neuroepidemiology 14:240–257 · DOI
  188. Hebert R, Lindsay J, Verreault R, Rockwood K, Hill G, Dubois MF (2000) Vascular dementia: incidence and risk factors in the Canadian study of health and aging. Stroke 31:1487–1493 · DOI
  189. Heier LA, Bauer CJ, Schwartz L, Zimmerman RD, Morgello S, Deck MD (1989) Large Virchow–Robin spaces: MR-clinical correlation. AJNR Am J Neuroradiol 10:929–936
  190. Henon H, Pasquier F, Durieu I, Godefroy O, Lucas C, Lebert F, Leys D (1997) Preexisting dementia in stroke patients. Baseline frequency, associated factors, and outcome. Stroke 28:2429–2436 · DOI
  191. Henon H, Durieu I, Guerouaou D, Lebert F, Pasquier F, Leys D (2001) Poststroke dementia: incidence and relationship to prestroke cognitive decline. Neurology 57:1216–1222 · DOI
  192. Hentschel F, Kreis M, Damian M, Krumm B (2003) [Microangiopathic lesions of white matter. Quantitation of cerebral MRI findings and correlation with psychological tests]. Nervenarzt 74:355–361 · DOI
  193. Herholz K, Perani D, Morris JC (2006) The dementias: early diagnosis and evaluation. Taylor & Francis, New York · DOI
  194. Heyman A, Fillenbaum G, Welsh-Bohmer KA et al (1998) Cerebral infarcts in patients with autopsy-proven Alzheimer’s disease, CERAD, Part XVIII (Abstr.). Neurology 51:159–162 · DOI
  195. Hill MD, Silver FL, Austin PC, Tu JV (2000) Rate of stroke recurrence in patients with primary intracerebral hemorrhage. Stroke 31:123–127 · DOI
  196. Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Moller M, Revesz T (2002) Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. J Neuropathol Exp Neurol 61:254–267 · DOI
  197. Hughes W (1965) Hypothesis—origin of lacunes. Lancet 2:19–21 · DOI
  198. Hyman BT, Trojanowski JQ (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 56:1095–1097 · DOI · Paper page
  199. Hyman BT (1998) New neuropathological criteria for Alzheimer disease. Arch Neurol 55:1174–1176 · DOI
  200. Ikeda M, Hokoishi K, Maki N, Nebu A, Tachibana N, Komori K, Shigenobu K, Fukuhara R, Tanabe H (2001) Increased prevalence of vascular dementia in Japan: a community-based epidemiological study. Neurology 57:839–844 · DOI

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Metadata

Authors
Jellinger, K. A.
Venue
Acta Neuropathologica
Publisher
Springer Science and Business Media LLC
Published
2007-02-07
Volume
113
Issue
4
Pages
349-388
ISSN
  • 0001-6322
  • 1432-0533
DOI
10.1007/s00401-006-0185-2
Cited by
166
References
49
Language
en
Licence
www.springer.com/tdm (tdm)

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