Mood improvement reduces memory complaints in depressed patients
Abstract
Background The aim was to examine associations between memory complaints, cognitive performance and mood in 174 adult, clinically depressed, neurologically healthy patients at baseline and during six months of follow-up.Methods Subjective memory disturbance was assessed using the Memory Complaint Questionnaire (MCQ). Levels of cognitive function, including memory, were assessed using a battery of neuropsychological tests. Mood and personality traits were assessed using rating scales, including the Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HDRS) and the 90-item Symptom Check List (SCL-90).Results At baseline, patients complaining of memory disturbances had higher BDI and HDRS scores than patients not complaining of memory problems. They also did less well in objective memory performances but not in other cognitive functions. Complaints of memory problems decreased during the follow-up. This change was associated with mood improvement and with reductions in other mental symptoms but not with changes in cognitive performance. In logistic regression analysis factors independently associated with MCQ change were age (OR 0.96) and BDI change (OR 1.06).Conclusions Subjective memory problems usually decline if depression is alleviated.
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Research has highlighted discrepancies between objectively measured cognitive function and patients' self-report from questionnaires, with the latter being affected by depressed mood.
“Research has highlighted discrepancies between objectively measured cognitive function and patients’ self-report from questionnaires, with the latter being affected by depressed mood [15,24,25].”
From Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study (2019) · cites this paper as [25]
Discrepancies between objectively and subjectively assessed cognitive function have been reported, with subjective assessments affected by depressed mood.
“Discrepancies between objectively and subjectively assessed cognitive function have been reported before, with the latter being affected by depressed mood [15,24,25].”
From Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study (2019) · cites this paper as [25]
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- Authors
- Antikainen, R., Hänninen, T., Honkalampi, K., Hintikka, J., Koivumaa-Honkanen, H., Tanskanen, A., & Viinamäki, H.
- Affiliations
- Kuopio University Hospital (FI)
- Venue
- European Archives of Psychiatry and Clinical Neuroscience
- Published
- 2001-03-21
- Volume
- 251
- Issue
- 1
- Pages
- 6-11
- ISSN
- 0003-9373 (ISSN-L)
- 0940-1334
- 1433-8491
- OpenAlex
- W2070699184
- Cited by
- 93
- References
- 24
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 6 · 2020: 3 · 2019: 4 · 2018: 5 · 2017: 2 · 2016: 3 · 2015: 10 · 2014: 4 · 2013: 6 · 2012: 3
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- European Archives of Psychiatry and Clinical Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, subjective memory complaints, memory impairment, mood improvement, cognitive performance, memory, personality traits
- MeSH terms
- Adult, Affect, Antidepressive Agents, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neuropsychological Tests, Psychiatric Status Rating Scales, Mental Recall, Wechsler Scales, Treatment Outcome
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