Cited by 178Sports Performance and TrainingExercise and Physiological ResponsesMuscle metabolism and nutrition

Time course of recovery following resistance training leading or not to failure

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Morán-Navarro, Ricardo, Pérez, Carlos E., Mora-Rodríguez, Ricardo, de la Cruz-Sánchez, Ernesto, González-Badillo, Juan José, Sánchez-Medina, Luis, Pallarés, Jesús G.·2017·European Journal of Applied Physiology

Abstract

Purpose To describe the acute and delayed time course of recovery following resistance training (RT) protocols differing in the number of repetitions (R) performed in each set (S) out of the maximum possible number (P).Methods Ten resistance-trained men undertook three RT protocols [S × R(P)]: (1) 3 × 5(10), (2) 6 × 5(10), and (3) 3 × 10(10) in the bench press (BP) and full squat (SQ) exercises. Selected mechanical and biochemical variables were assessed at seven time points (from - 12 h to + 72 h post-exercise). Countermovement jump height (CMJ) and movement velocity against the load that elicited a 1 m s-1 mean propulsive velocity (V1) and 75% 1RM in the BP and SQ were used as mechanical indicators of neuromuscular performance.Results Training to muscle failure in each set [3 × 10(10)], even when compared to completing the same total exercise volume [6 × 5(10)], resulted in a significantly higher acute decline of CMJ and velocity against the V1 and 75% 1RM loads in both BP and SQ. In contrast, recovery from the 3 × 5(10) and 6 × 5(10) protocols was significantly faster between 24 and 48 h post-exercise compared to 3 × 10(10). Markers of acute (ammonia, growth hormone) and delayed (creatine kinase) fatigue showed a markedly different course of recovery between protocols, suggesting that training to failure slows down recovery up to 24-48 h post-exercise.Conclusions RT leading to failure considerably increases the time needed for the recovery of neuromuscular function and metabolic and hormonal homeostasis. Avoiding failure would allow athletes to be in a better neuromuscular condition to undertake a new training session or competition in a shorter period of time.

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  • Pushing every set to absolute failure exponentially increases neuromuscular fatigue, prolongs recovery demands, and reduces the quality of subsequent sets or sessions.

    “However, pushing every set to absolute failure exponentially increases neuromuscular fatigue, prolongs recovery demands, and reduces the quality of subsequent sets or sessions [148].”

    From Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators (2026) · cites this paper as [148]

    The Discussion reports a greater acute decline in neuromuscular performance after sets taken to failure and slower recovery over the following 24–48 hours; the Abstract says avoiding failure could leave athletes in better condition for a subsequent session. Neither passage establishes an exponential increase in fatigue or measures the quality of subsequent sets. Page numbers were not supplied in our copy. (LLM, conf=0.88)

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Research works printed but not linked: 1

  1. Smilios I, Pilianidis T, Karamouzis M, Tokmakidis SP. Hormonal responses after various resistance exercise protocols. Med Sci Sports Exerc. 2003;35(4):644-654

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Authors
Morán-Navarro, R., Pérez, C. E., Mora-Rodríguez, R., de la Cruz-Sánchez, E., González-Badillo, J. J., Sánchez-Medina, L., & Pallarés, J. G.
Affiliations
  • Universidad de Murcia (ES)
  • University of Castilla-La Mancha (ES)
Corresponding author
Pallarés, Jesús G.
Venue
European Journal of Applied Physiology
Published
2017-09-30
Volume
117
Issue
12
Pages
2387-2399
ISSN
  • 0020-9376 (ISSN-L)
  • 1439-6319
  • 1439-6327
OpenAlex
W2757710276
Cited by
178
References
36
Citations by year
2026: 17 · 2025: 13 · 2024: 14 · 2023: 17 · 2022: 30 · 2021: 24 · 2020: 32 · 2019: 20 · 2018: 8 · 2017: 1 · 2013: 1
FWCI
18.22
Type
journal article
Language
en
Open access
Locations
  • European Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
  • Academica-e (Universidad Pública de Navarra) (submittedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Keywords
resistance training, training to failure, recovery time course, neuromuscular fatigue, countermovement jump, movement speed, bench press, squatting, creatine kinase, ammonia, growth hormone, exercise volume, acute fatigue
MeSH terms
Adult, Humans, Male, Random Allocation, Muscle, Skeletal, Muscle Fatigue, Recovery of Function, Resistance Training

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