Cited by 193Balance, Gait, and Falls PreventionStroke Rehabilitation and RecoveryParkinson's Disease Mechanisms and Treatments

Treadmill training for the treatment of gait disturbances in people with Parkinson's disease: a mini-review

Herman, T., Giladi, N., Hausdorff, J. M.·2009·Journal of Neural Transmission

Abstract

This report reviews recent investigations of the effects of treadmill training (TT) on the gait of patients with Parkinson's disease. A literature search identified 14 relevant studies. Three studies reported on the immediate effects of TT; over-ground walking improved (e.g., increased speed and stride length) after one treadmill session. Effects persisted even 15 min later. Eleven longer-term trials demonstrated feasibility, safety and efficacy, reporting positive benefits in gait speed, stride length and other measures such as disease severity (e.g., Unified Parkinson's Disease Rating Scale) and health-related quality of life, even several weeks after cessation of the TT. Long-term carryover effects also raise the possibility that TT may elicit positive neural plastic changes. While encouraging, the work to date is preliminary; none of the identified studies received a quality rating of Gold or level Ia. Additional high quality randomized controlled studies are needed before TT can be recommended with evidence-based support.

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Registry

Crossref · 10.1007/s00702-008-0139-z

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85 of 85 references verified0 citation errors · 0 not checkable

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  • Treadmill exercise studies have shown that individuals with mild to moderate Parkinson's disease can improve gait performance, including velocity, stride length, cadence, postural stability, gait rhythmicity, and joint excursion.

    “Studies, using treadmill exercise (with or without body weight support typically used for the purpose of maintaining safety) have shown that through exercise practice individuals with mild to moderate stages of PD can improve gait performance, including velocity, stride length, cadence, postural stability, gait rhythmicity, and joint excursion 24, 25.”

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Authors
Herman, T., Giladi, N., & Hausdorff, J. M.
Affiliations
  • Tel Aviv Sourasky Medical Center (IL)
  • Tel Aviv University (IL)
  • Harvard University (US)
Corresponding author
Hausdorff, J. M.
Venue
Journal of Neural Transmission
Published
2008-11-04
Volume
116
Issue
3
Pages
307-318
ISSN
  • 0300-9564 (ISSN-L)
  • 1435-1463
OpenAlex
W2101329822
Cited by
193
References
86
Citations by year
2026: 3 · 2025: 3 · 2024: 14 · 2023: 8 · 2022: 5 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 12 · 2017: 10 · 2016: 13 · 2015: 18 · 2014: 18 · 2013: 15 · 2012: 16
FWCI
1.40
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Neural Transmission (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • European Commission
  • National Institutes of Health
  • National Institute on Aging (AG 14100)
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
Keywords
treadmill training, Parkinson's disease, gait disturbance, walking speed, stride length, residual effects, neuroplasticity, health-related quality of life, exercise therapy
MeSH terms
Clinical Trials as Topic, Exercise Therapy, Gait, Humans, Parkinson Disease, Quality of Life, Severity of Illness Index, Time Factors, Treatment Outcome

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