Post-traumatic stress disorder and diabetes: co-morbidity and outcomes in a male veterans sample

Trief, Paula M.; Ouimette, Paige; Wade, Michael; Shanahan, Paul; Weinstock, Ruth S.

doi:10.1007/s10865-006-9067-2

Cited by 104Posttraumatic Stress Disorder ResearchDiabetes Management and EducationMigration, Health and Trauma

Post-traumatic stress disorder and diabetes: co-morbidity and outcomes in a male veterans sample

Trief, Paula M., Ouimette, Paige, Wade, Michael, Shanahan, Paul, Weinstock, Ruth S.·2006·Journal of Behavioral Medicine

DOI 10.1007/s10865-006-9067-2

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Abstract

The purpose of this study was to assess the prevalence and correlates of comorbid diabetes and Post-Traumatic Stress disorder(PTSD)and potential relationships between PTSD and diabetes outcomes. Male patients enrolled in a VA primary care database (N = 73,270) were classified as having diabetes from pharmacy records (N = 14,438) and grouped into those with diagnoses of PTSD with depression (N = 649), PTSD-only (N = 480), Depression-only (N = 1696), Other psychiatric diagnosis (N = 736), or No psychiatric diagnosis (N = 10,877) based on the Purpose of Visit diagnoses in the medical record. Outcomes included glycemic control (HbA1c), cholesterol and triglycerides. Correlates were age, substance use disorder, other psychiatric diagnosis, number of primary care encounters, and medications. The prevalence of comorbid diabetes and PTSD was 8% (n = 1129). Of these, 57% (n = 649) had comorbid depression. Patients with PTSD and depression had higher rates of substance use disorder and higher cholesterol and LDL. Patients with depression had poorer glycemic control. Patients with PTSD and depression weighed more and had higher BMI than patients with neither diagnosis. Thus, male diabetes patients with PTSD and depression may be vulnerable to substance use disorders and to weight/lipid problems that can affect health. Depression is a likely contributor to poor glycemic control. Careful screening for mental health comorbidities is needed for diabetes patients.

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Severe hypoglycemia has been associated with PTSD, PTSD-like symptoms, and panic disorder symptoms.
“Occurrence of severe hypoglycemia has been shown to be associated with PTSD and PTSD-like and panic disorder symptoms (74,75).”
From Psychosocial care for people with diabetes: a position statement of the American Diabetes Association (2016) · cites this paper as [75]

The central role of the propensity score in observational studies for causal effects
ROSENBAUM, P. R., & RUBIN, D. B. (1983) · Biometrika · doi:10.1093/biomet/70.1.41 · Cited by 31,241 · see citing works
Posttraumatic Stress Disorder in the National Comorbidity Survey
Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379 · see citing works
Combat Duty in Iraq and Afghanistan, Mental Health Problems, and Barriers to Care
Hoge, C. W., Castro, C. A., Messer, S. C., McGurk, D., Cotting, D. I., & Koffman, R. L. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040603 · Cited by 4,778 · see citing works
The Prevalence of Comorbid Depression in Adults With Diabetes
Anderson, R. J., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.6.1069 · Cited by 3,926 · see citing works
Prevalence of civilian trauma and posttraumatic stress disorder in a representative national sample of women.
Resnick, H. S., Kilpatrick, D. G., Dansky, B. S., Saunders, B. E., & al, E. (1993) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.61.6.984 · Cited by 1,868 · see citing works
Prevalence of civilian trauma and posttraumatic stress disorder in a representative national sample of women.
Resnick, H. S., Kilpatrick, D. G., Dansky, B. S., Saunders, B. E., & Best, C. L. (1993) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.61.6.984 · Cited by 1,868 · see citing works
Depression and poor glycemic control: a meta-analytic review of the literature.
Lustman, P. J., Anderson, R. J., Freedland, K. E., de Groot, M., Carney, R. M., & Clouse, R. E. (2000) · Diabetes Care · doi:10.2337/diacare.23.7.934 · Cited by 1,854 · see citing works
Association of depression and diabetes complications: a meta-analysis
de Groot, M., Anderson, R., Freedland, K. E., Clouse, R. E., & Lustman, P. J. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200107000-00015 · Cited by 1,799 · see citing works
Trauma and the Vietnam War generation: report of findings from the National Vietnam Veterans Readjustment Study
(1990) · Choice Reviews Online · doi:10.5860/choice.27-6366 · Cited by 1,627 · see citing works
Relationship of Depression and Diabetes Self-Care, Medication Adherence, and Preventive Care
Lin, E. H. B., Katon, W., Von Korff, M., Rutter, C., Simon, G. E., Oliver, M., Ciechanowski, P., Ludman, E. J., Bush, T., & Young, B. (2004) · Diabetes Care · doi:10.2337/diacare.27.9.2154 · Cited by 1,146 · see citing works
Post-traumatic stress disorder in the community: an epidemiological study
Davidson, J. R. T., Hughes, D., Blazer, D. G., & George, L. K. (1991) · Psychological Medicine · doi:10.1017/s0033291700022352 · Cited by 969 · see citing works
Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies
BOSCARINO, J. A. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1314.011 · Cited by 691 · see citing works
Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment
Musselman, D. L., Betan, E. J., Larsen, H., & Phillips, L. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00569-9 · Cited by 670 · see citing works
Post-Traumatic Stress Disorder and Chronic Fatigue Syndrome-like Illness among Gulf War Veterans: A Population-based Survey of 30,000 Veterans
Kang, H. K. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwf187 · Cited by 524 · see citing works
Levels and risks of depression and anxiety symptomatology among diabetic adults
Peyrot, M., & Rubin, R. R. (1997) · Diabetes Care · doi:10.2337/diacare.20.4.585 · Cited by 488 · see citing works
Depression and All-Cause and Coronary Heart Disease Mortality Among Adults With and Without Diabetes
Egede, L. E., Nietert, P. J., & Zheng, D. (2005) · Diabetes Care · doi:10.2337/diacare.28.6.1339 · Cited by 473 · see citing works
Posttraumatic Stress Symptoms, Intrusive Thoughts, Loss, and Immune Function after Hurricane Andrew
Ironson, G. H., Wynings, C., Schneiderman, N., Baum, A. E., Rodriguez, M. S., Greenwood, D., Benight, C. C., Antoni, M. H., LaPerriere, A. R., Huang, H.-S., et al. (1997) · Psychosomatic Medicine · doi:10.1097/00006842-199703000-00003 · Cited by 435 · see citing works
Trauma and the Vietnam War Generation: Report of Findings from the National Vietnam Veterans Readjustment Study
Kudler, H. S. (1991) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199110000-00024 · Cited by 434 · see citing works
Disparities in Diabetes Care: Impact of Mental Illness
Frayne, S. M., Halanych, J. H., Miller, D. R., Wang, F., Lin, H., Pogach, L., Sharkansky, E. J., Keane, T. M., Skinner, K. M., Rosen, C. S., et al. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.22.2631 · Cited by 336 · see citing works
Anxiety and Poor Glycemic Control: A Meta-Analytic Review of the Literature
Anderson, R. J., Grigsby, A. B., Freedland, K. E., De Groot, M., McGill, J. B., Clouse, R. E., & Lustman, P. J. (2002) · The International Journal of Psychiatry in Medicine · doi:10.2190/klgd-4h8d-4ryl-twq8 · Cited by 328 · see citing works
Health Status, Somatization, and Severity of Posttraumatic Stress Disorder in Vietnam Combat Veterans With Posttraumatic Stress Disorder
Beckham, J. C., Moore, S. D., Feldman, M. E., Hertzberg, M. A., Kirby, A. C., & Fairbank, J. A. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.11.1565 · Cited by 269 · see citing works
Symptoms of depression as a risk factor for incident diabetes: findings from the National Health and Nutrition Examination Epidemiologic Follow-up Study, 1971-1992
Carnethon, M. R. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwg172 · Cited by 244 · see citing works
Physical health and post-traumatic stress disorder: review and synthesis.
Schnurr, P. P., & Jankowski, M. K. (1999) · PubMed · Cited by 239 · see citing works
Health Status of Vietnam Veterans
(1988) · JAMA · doi:10.1001/jama.1988.03720180027028 · Cited by 210 · see citing works
Nonpsychiatric Illness Among Primary Care Patients With Trauma Histories and Posttraumatic Stress Disorder
Weisberg, R. B., Bruce, S. E., Machan, J. T., Kessler, R. C., Culpepper, L., & Keller, M. B. (2002) · Psychiatric Services · doi:10.1176/appi.ps.53.7.848 · Cited by 198 · see citing works
The relationship between trauma, post-traumatic stress disorder, and physical health.
Friedman, M. J., & Schnurr, P. P. (1995) · Cited by 186 · see citing works
Depression and coronary heart disease in women with diabetes
Clouse, R. E., Lustman, P. J., Freedland, K. E., Griffith, L. S., McGill, J. B., & Carney, R. M. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000041624.96580.1f · Cited by 179 · see citing works
A Descriptive and Comparative Study of the Prevalence of Depressive and Anxiety Disorders in Low-Income Adults With Type 2 Diabetes and Other Chronic Illnesses
Thomas, J., Jones, G. N., Scarinci, I. C., & Brantley, P. J. (2003) · Diabetes Care · doi:10.2337/diacare.26.8.2311 · Cited by 155 · see citing works
Predictors and outcomes of posttraumatic stress disorder in World War II veterans exposed to mustard gas.
Schnurr, P. P., Ford, J. D., Friedman, M. J., Green, B. L., Dain, B. J., & Sengupta, A. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.2.258 · Cited by 146 · see citing works
Burden of Medical Illness in Women With Depression and Posttraumatic Stress Disorder
Frayne, S. M., Seaver, M. R., Loveland, S. A., Christiansen, C. L., Spiro, A., Parker, V. A., & Skinner, K. M. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.12.1306 · Cited by 125 · see citing works
Posttraumatic stress disorder and health status among female and male medical patients
Ouimette, P. C., Cronkite, R. C., Henson, B. R., Prins, A., Gima, K. S., & Moos, R. H. (2004) · Journal of Traumatic Stress · doi:10.1023/b:jots.0000014670.68240.38 · Cited by 119 · see citing works
Self-citation
Mental Health Care Needs among Recent War Veterans
Kang, H. K., & Hyams, K. C. (2005) · New England Journal of Medicine · doi:10.1056/nejmp058024 · Cited by 107 · see citing works
Self-reported diabetes and posttraumatic stress disorder among adults in the community
Goodwin, R. D., & Davidson, J. R. T. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2004.07.013 · Cited by 100 · see citing works
Relationship between posttraumatic stress disorder and self-reported physical symptoms in Persian Gulf War veterans.
Baker, D. G., Mendenhall, C. L., Simbartl, L. A., Magan, L. K., & Steinberg, J. L. (1997) · PubMed · Cited by 89 · see citing works
Health status of Vietnam veterans. I. Psychosocial characteristics. The Centers for Disease Control Vietnam Experience Study
(1988) · JAMA · doi:10.1001/jama.259.18.2701 · Cited by 75 · see citing works
Relationship Between Posttraumatic Stress Disorder and Self-Reported Physical Symptoms in Persian Gulf War Veterans
Baker, D. G. (1997) · Archives of Internal Medicine · doi:10.1001/archinte.1997.00440390062009 · Cited by 66 · see citing works
Biobehavioral Stress Response: Protective And Damaging Effects
Yehuda, R., & McEwen, B. S. (2004) · Medical Entomology and Zoology · Cited by 59 · see citing works
Somatic Complaints, Stress Reaction, and Posttraumatic Stress Disorder: A Three-Year Follow-up Study
Solomon, Z. (1988) · Behavioral Medicine · doi:10.1080/08964289.1988.9935143 · Cited by 45 · see citing works
Finding a home for post-traumatic stress disorder in biological psychiatry
Sullivan, G. M., & Gorman, J. M. (2002) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(01)00010-7 · Cited by 17 · see citing works
Diabetes Care in the Veterans Health Administration
Haas, L. B., & Watts, S. A. (2005) · Diabetes Spectrum · doi:10.2337/diaspect.18.3.159 · Cited by 4 · see citing works

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Psychosocial care for people with diabetes: a position statement of the American Diabetes Association
Young-Hyman, D., de Groot, M., Hill-Briggs, F., Gonzalez, J. S., Hood, K., & Peyrot, M. (2016) · Diabetes Care · doi:10.2337/dc16-2053 · Cited by 1,072 · see citing works
The physical health consequences of PTSD and PTSD symptoms: A meta-analytic review
Pacella, M. L., Hruska, B., & Delahanty, D. L. (2013) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2012.08.004 · Cited by 677 · see citing works
Posttraumatic Stress Disorder, Cardiovascular, and Metabolic Disease: A Review of the Evidence
Dedert, E. A., Calhoun, P. S., Watkins, L. L., Sherwood, A., & Beckham, J. C. (2010) · Annals of Behavioral Medicine · doi:10.1007/s12160-010-9165-9 · Cited by 263 · see citing works
Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: Evidence from the general population
Spitzer, C., Barnow, S., Völzke, H., Wallaschofski, H., John, U., Freyberger, H. J., Löwe, B., & Grabe, H. J. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.06.002 · Cited by 205 · see citing works
Psychological conditions in adults with diabetes.
de Groot, M., Golden, S. H., & Wagner, J. (2016) · American Psychologist · doi:10.1037/a0040408 · Cited by 170 · see citing works
Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population
Weiss, T., Skelton, K., Phifer, J., Jovanovic, T., Gillespie, C. F., Smith, A., Umpierrez, G., Bradley, B., & Ressler, K. J. (2011) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2011.01.002 · Cited by 87 · see citing works
Posttraumatic stress disorder and new-onset diabetes among adult survivors of the World Trade Center disaster
Miller-Archie, S. A., Jordan, H. T., Ruff, R. R., Chamany, S., Cone, J. E., Brackbill, R. M., Kong, J., Ortega, F., & Stellman, S. D. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.05.016 · Cited by 79 · see citing works
The association between childhood trauma and lipid levels in an adult low-income, minority population
Spann, S. J., Gillespie, C. F., Davis, J. S., Brown, A., Schwartz, A., Wingo, A., Habib, L., & Ressler, K. J. (2014) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2013.10.004 · Cited by 33 · see citing works
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Mejia, C. R., Serna-Alarcón, V., Vilela-Estrada, M. A., Armada, J., Ubillus, M., Beraún-Barrantes, J., Álvarez-Risco, A., Del-Aguila-Arcentales, S., Davies, N. M., & Yáñez, J. A. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1302694 · Cited by 5 · see citing works

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Derks, W., de Leeuw, R. J., & Hordijk, G. J. (2005) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/01.moo.0000156169.63204.39 · Cited by 66 · see citing works
Influence of comorbidity on the choice of treatment and survival of elderly patients with advanced non-small cell lung cancer
Ai-wu, Li, Caicun, et al. (2008) · Acta Scientiarum Naturalium Universitatis Sunyatseni
Health Care Resource Utilization And Costs Associated With HIV-Positive Patients With Comorbidity Versus HIV-Negative Patients With Comorbidity
Lachaîne, J., Baribeau, V., Lorgeoux, R.-P., et al. (2017) · Value in Health · doi:10.1016/j.jval.2017.08.2323 · Cited by 4 · see citing works
Comorbidity in head and neck cancer: A critical appraisal and recommendations for practice
Paleri, V., Wight, R. G., Silver, C. E., Haigentz, M., Takes, R. P., Bradley, P. J., Rinaldo, A., Sanabria, Á., Bień, S., & Ferlito, A. (2010) · Oral Oncology · doi:10.1016/j.oraloncology.2010.07.008 · Cited by 247 · see citing works
Assessing the impact of comorbidity in the older population
Guralnik, J. M. (1996) · Annals of Epidemiology · doi:10.1016/s1047-2797(96)00060-9 · Cited by 224 · see citing works

Authors: Trief, P. M., Ouimette, P., Wade, M., Shanahan, P., & Weinstock, R. S.
Affiliations: United States Department of Veterans Affairs (US)
Syracuse VA Medical Center (US)
SUNY Upstate Medical University (US)
ORCID: Trief, Paula M.
Wade, Michael
Weinstock, Ruth S.
Venue: Journal of Behavioral Medicine
Publisher: Springer Science and Business Media LLC
Published: 2006-07-25
Volume: 29
Issue: 5
Pages: 411-418
ISSN: 0160-7715 (ISSN-L)
1573-3521
DOI: 10.1007/s10865-006-9067-2
OpenAlex: W2068390456
Cited by: 104
References: 40
Citations by year: 2026: 1 · 2025: 1 · 2024: 8 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 8 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 10 · 2015: 6 · 2014: 6 · 2013: 6 · 2012: 12
FWCI: 4.79
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Behavioral Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Social Sciences › Psychology › Clinical Psychology › Migration, Health and Trauma
Keywords: post-traumatic stress disorder, diabetes mellitus, comorbidities, depression, veterans, glycemic control, HbA1c, cholesterol, substance use disorders, body mass index, lipid profile, primary care, mental health screening
MeSH terms: Aged, Blood Glucose, Cholesterol, Combat Disorders, Cross-Sectional Studies, Depressive Disorder, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Glycated Hemoglobin, Humans, Male, Middle Aged, Statistics as Topic, Triglycerides, Veterans, Health Behavior, Comorbidity, Body Mass Index, Treatment Refusal, Treatment Outcome, Substance-Related Disorders

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Post-traumatic stress disorder and diabetes: co-morbidity and outcomes in a male veterans sample

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