Cited by 167Parkinson's Disease Mechanisms and TreatmentsNeurotransmitter Receptor Influence on BehaviorTryptophan and brain disorders

The DOI matches its Crossref record; 168 of the 170 references it cites were found in a registry or an index, and 2 are not checked yet.

The Role of Oxidative Stress, Metabolic Compromise, and Inflammation in Neuronal Injury Produced by Amphetamine-Related Drugs of Abuse

Open access

Yamamoto, Bryan K., Raudensky, Jamie·2008·Journal of Neuroimmune Pharmacology

DOI 10.1007/s11481-008-9121-7PMC PMC3955110

Open this paper in CoChat — free account

Abstract

Methamphetamine (METH) and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) are amphetamine derivatives with high abuse liability. These amphetamine-related drugs of abuse mediate their effects through the acute activation of both dopaminergic and serotonergic neurons. Long-term abuse of these amphetamine derivatives, however, results in damage to both dopaminergic and serotonergic terminals throughout the brain. This toxicity is mediated in part by oxidative stress, metabolic compromise, and inflammation. The overall objective of this review is to highlight experimental evidence that METH and MDMA increase oxidative stress, produce mitochondrial dysfunction, and increase inflammation that converge and culminate in the long-term toxicity to dopaminergic and serotonergic neurons.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/s11481-008-9121-7

Cites

168 of 170 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Hydroperoxide metabolism in mammalian organs.
Chance, B., Sies, H., & Boveris, A. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.3.527 · Cited by 5,827
Microglia: a sensor for pathological events in the CNS
Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
Epstein, F. H., Lipton, S. A., & Rosenberg, P. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403033300907 · Cited by 2,676
Peroxynitrite oxidation of sulfhydryls.
Radí, R., Beckman, J. S., Bush, K., & Freeman, B. Α. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)64313-7 · Cited by 2,492
Microglia as a source and target of cytokines
Hanisch, U. (2002) · Glia · doi:10.1002/glia.10161 · Cited by 1,645
Mechanisms of neurotransmitter release by amphetamines: A review
Sulzer, D., Sonders, M. S., Poulsen, N. W., & Galli, A. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.04.003 · Cited by 1,243
NMDA-dependent superoxide production and neurotoxicity
Lafon‐Cazal, M., Pietri, S., Culcasi, M., & Bockaert, J. (1993) · Nature · doi:10.1038/364535a0 · Cited by 1,183
Reactive microgliosis
Streit, W. J., Walter, S. A., & Pennell, N. A. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00069-0 · Cited by 1,096
Metalloproteinases in biology and pathology of the nervous system
Yong, W. V., Power, C., Forsyth, P., & Edwards, D. (2001) · Nature Reviews Neuroscience · doi:10.1038/35081571 · Cited by 1,094
Structural Abnormalities in the Brains of Human Subjects Who Use Methamphetamine
Thompson, P. M., Hayashi, K. M., Simon, S. L., Geaga, J. A., Hong, M., Sui, Y., Lee, J. Y., Toga, A. W., Ling, W. W., & London, E. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0713-04.2004 · Cited by 770
The role of microglia and macrophages in the pathophysiology of the CNS
Stollg, G., & Jander, S. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00083-5 · Cited by 683
Matrix metalloproteinases and diseases of the CNS
Yong, V. W., Forsyth, P. A., Bell, R. B., Krekoski, C. A., & Edwards, D. R. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01169-7 · Cited by 635
Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428
McCann, U. D., Wong, D. F., Yokoi, F., Villemagne, V., Dannals, R. F., & Ricaurte, G. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-20-08417.1998 · Cited by 602 · cited 1×
“Clinical studies using functional magnetic resonance imaging to measure changes in DAT levels in human METH abusers indicate that chronic use of METH results in decreased DAT in the striatum that persists for up to 3 years following abstinence (McCann et al. 1998).”
Background
NMDA receptors activate the arachidonic acid cascade system in striatal neurons
Dumuis, A., Sebben, M., Haynes, L., Pin, J., & Bockaert, J. (1988) · Nature · doi:10.1038/336068a0 · Cited by 593
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity
O’Hearn, E., Battaglia, G., Souza, E. B. D., Kuhar, M. J., & Me, M. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-08-02788.1988 · Cited by 543
Molecular Mechanisms of Glutamate Receptor-Mediated Excitotoxic Neuronal Cell Death
Sattler, R., & Tymianski, M. (2001) · Molecular Neurobiology · doi:10.1385/mn:24:1-3:107 · Cited by 537
Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine
Wagner, G. C., Ricaurte, G. A., Seiden, L. S., Schuster, C. R., Miller, R. J., & Westley, J. (1980) · Brain Research · doi:10.1016/0006-8993(80)91265-2 · Cited by 523
Monoamine transporters and psychostimulant drugs.
Rothman, R., & Baumann, M. (2003) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2003.08.054 · Cited by 509
Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory
Nagy, V., Bozdagi, O., Matynia, A., Balcerzyk, M., Okulski, P., Dzwonek, J., Costa, R. M., Silva, A. J., Kaczmarek, L., & Huntley, G. W. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4359-05.2006 · Cited by 499
Nitric oxide neurotoxicity
Dawson, V. L., & Dawson, T. M. (1996) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(96)00148-2 · Cited by 498
Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: A regional study
Ricaurte, G. A., Schuster, C. R., & Seiden, L. S. (1980) · Brain Research · doi:10.1016/0006-8993(80)90952-x · Cited by 490
Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain
Ricaurte, G. A., Guillery, R. W., Seiden, L. S., Schuster, C. R., & Moore, R. Y. (1982) · Brain Research · doi:10.1016/0006-8993(82)90198-6 · Cited by 479
Molecular mechanisms of calcium-dependent excitotoxicity
Sattler, R., & Tymianski, M. (2000) · Journal of Molecular Medicine · doi:10.1007/s001090000077 · Cited by 477
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
Battaglia, G., Yeh, S. Y., O’Hearn, E., Molliver, M. E., Kuhar, M. J., & Souza, E. B. D. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39191-3 · Cited by 458
Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
Volterra, A., Trotti, D., Tromba, C., FLORIDI, S., & Racagni, G. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02924.1994 · Cited by 457
Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine
LaVoie, M. J., & Hastings, T. G. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-04-01484.1999 · Cited by 449
Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain.
Hotchkiss, A. J., & Gibb, J. W. (1980) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)32165-8 · Cited by 443
Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo
Siman, R. G., & Noszek, J. C. (1988) · Neuron · doi:10.1016/0896-6273(88)90076-1 · Cited by 434
Further studies of the role of hyperthermia in methamphetamine neurotoxicity.
Bowyer, J. F., Davies, D. L., Schmued, L. C., Broening, H. W., Newport, G. D., Slikker, W., & Holson, R. R. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38650-7 · Cited by 412
Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse.
O'Callaghan, J. P., & Miller, D. B. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22433-8 · Cited by 409
Matrix Metalloproteinase-9 Undergoes Expression and Activation during Dendritic Remodeling in Adult Hippocampus
Szklarczyk, A., Lapinska, J., Rylski, M., McKay, R. D. G., & Kaczmarek, L. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-03-00920.2002 · Cited by 392
Matrix Metalloproteinase Inhibition Prevents Oxidative Stress-Associated Blood–Brain Barrier Disruption after Transient Focal Cerebral Ischemia
Gasche, Y., Copin, J., Sugawara, T., Fujimura, M., & Chan, P. H. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200112000-00003 · Cited by 388
Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures
Rosenberg, G. A., Cunningham, L. A., Wallace, J., Alexander, S., Estrada, E. Y., Grossetete, M., Razhagi, A., Miller, K., & Gearing, A. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03294-7 · Cited by 388
An introduction to the free radical hypothesis in Parkinson's disease
Olanow, C. W. (1992) · Annals of Neurology · doi:10.1002/ana.410320703 · Cited by 382
Matrix metalloproteinases in brain development and remodeling: Synaptic functions and targets
Ethell, I. M., & Ethell, D. W. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21273 · Cited by 378
Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals
Ricaurte, G. A., Bryan, G. K., Strauss, L., Seiden, L. S., & Schuster, C. R. (1985) · Science · doi:10.1126/science.4023719 · Cited by 367
Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3, 4-methylenedioxymethamphetamine
Nash, J. F., & Yamamoto, B. K. (1992) · Brain Research · doi:10.1016/0006-8993(92)90713-j · Cited by 354
Self-citation
The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain
Stone, D. M., Stahl, D. C., Hanson, G. R., & Gibb, J. W. (1986) · European Journal of Pharmacology · doi:10.1016/0014-2999(86)90555-8 · Cited by 346
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood–brain barrier dysfunction
Haorah, J., Ramirez, S. H., Schall, K. A., Smith, D. L., Pandya, R., & Persidsky, Y. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04393.x · Cited by 334
Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury
Dykens, J. A., Stern, A., & Trenkner, E. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb10014.x · Cited by 325
Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system
Hunter, R. L., Dragicevic, N., Seifert, K., Choi, D. Y., Liu, M., Kim, H., Cass, W. A., Sullivan, P. G., & Bing, G. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04327.x · Cited by 322
Selective microglial activation in the rat rotenone model of Parkinson's disease
Sherer, T., Betarbet, R. S., Kim, J.-H., & Greenamyre, J. T. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00172-1 · Cited by 317
Extracellular proteolysis in brain injury and inflammation: Role for plasminogen activators and matrix metalloproteinases
Lo, E. H., Wang, X., & Cuzner, M. L. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10270 · Cited by 310
Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys
Seiden, L. S., Fischman, M. W., & Schuster, C. R. (1976) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(76)90030-2 · Cited by 307
Role of dopamine in the neurotoxic effects of methamphetamine.
Schmidt, C. J., Ritter, J. K., Sonsalla, P. K., Hanson, G. R., & Gibb, J. W. (1985) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22853-1 · Cited by 300
(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates
Ricaurte, G. A. (1988) · JAMA · doi:10.1001/jama.1988.03410010059035 · Cited by 300
Cognitive performance in (±) 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") users: a controlled study
McCann, U., Mertl, M., Eligulashvili, V., & Ricaurte, G. A. (1999) · Psychopharmacology · doi:10.1007/s002130050967 · Cited by 300
Brain Serotonin Transporter Density and Aggression in Abstinent Methamphetamine Abusers
Sekine, Y., Ouchi, Y., Takei, N., Yoshikawa, E., Nakamura, K., Futatsubashi, M., Okada, H., Minabe, Y., Suzuki, K., Iwata, Y., et al. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.1.90 · Cited by 293
The Effects of Methamphetamine on the Production of Free Radicals and Oxidative Stress
Yamamoto, B. K., & Zhu, W. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37769-9 · Cited by 281
Self-citation
Methamphetamine-induced neuronal damage: A possible role for free radicals
Vito, M. J. D., & Wagner, G. C. (1989) · Neuropharmacology · doi:10.1016/0028-3908(89)90130-5 · Cited by 270
Rapid Communication: Attenuation of Methamphetamine‐Induced Neurotoxicity in Copper/Zinc Superoxide Dismutase Transgenic Mice
Cadet, J. L., Sheng, P., All, S., Rothman, R. B., Carlson, E. J., & Epstein, C. J. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62010380.x · Cited by 263
Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window
Rosenberg, G. A., Estrada, E. Y., Dencoff, J. E., & Stetler‐Stevenson, W. G. (1995) · Brain Research · doi:10.1016/0006-8993(95)01089-0 · Cited by 261
Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity
O'Callaghan, J. P., & Sriram, K. (2005) · Expert Opinion on Drug Safety · doi:10.1517/14740338.4.3.433 · Cited by 255
Oxidative modifications in nitrosative stress
Stamler, J. S., & Hausladen, A. (1998) · Nature Structural Biology · doi:10.1038/nsb0498-247 · Cited by 249
Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor‐α
Sriram, K., Miller, D. B., & O'Callaghan, J. P. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03566.x · Cited by 242 · cited 8×
“Moreover, the intracerebroventricular administration of IL-1β potentiated MDMA-induced 5HT toxicity (O’Shea et al. 2005).”
BackgroundInfluential
Increased Methamphetamine Neurotoxicity in Heterozygous Vesicular Monoamine Transporter 2 Knock-Out Mice
Fumagalli, F., Gainetdinov, R. R., Wang, Y., Valenzano, K. J., Miller, G. W., & Caron, M. G. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-07-02424.1999 · Cited by 241
Matrix metalloproteinases and free radicals in cerebral ischemia
JIANLIU, K., & Rosenberg, G. A. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.03.033 · Cited by 233
Gelatinase B modulates selective opening of the blood-brain barrier during inflammation
Mun-Bryce, S., & Rosenberg, G. A. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.274.5.r1203 · Cited by 230
Resveratrol potently reduces prostaglandin E2production and free radical formation in lipopolysaccharide-activated primary rat microglia
Candelario-Jalil, E., de Oliveira, A. C. P., Gräf, S., Bhatia, H. S., Hüll, M., Muñoz, E., & Fiebich, B. L. (2007) · Journal of Neuroinflammation · doi:10.1186/1742-2094-4-25 · Cited by 223
High-Dose Methamphetamine Acutely Activates the Striatonigral Pathway to Increase Striatal Glutamate and Mediate Long-Term Dopamine Toxicity
Mark, K. A., Soghomonian, J., & Yamamoto, B. K. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3597-04.2004 · Cited by 215
Self-citation
Multiphasic roles for matrix metalloproteinases after stroke
ROSELL, A., & LO, E. (2008) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.12.001 · Cited by 215
Differential effects of stimulants on monoaminergic transporters: Pharmacological consequences and implications for neurotoxicity
Fleckenstein, A. E., Gibb, J. W., & Hanson, G. R. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00639-7 · Cited by 213
Long-term effects of chronic methamphetamine administration in rhesus monkeys
Woolverton, W. L., Ricaurte, G. A., Forno, L. S., & Seiden, L. S. (1989) · Brain Research · doi:10.1016/0006-8993(89)91279-1 · Cited by 205
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users
McCann, U. D., Kuwabara, H., Kumar, A., Palermo, M., Abbey, R., Brašić, J. R., Ye, W., Alexander, M., Dannals, R. F., Wong, D. F., et al. (2007) · Synapse · doi:10.1002/syn.20471 · Cited by 205
Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity
LaVoie, M. J., Card, J. P., & Hastings, T. G. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.01.010 · Cited by 204
Quantitative PET Studies of the Serotonin Transporter in MDMA Users and Controls Using [11C]McN5652 and [11C]DASB
McCann, U. D., Szabó, Z. R., Seckin, E., Rosenblatt, P., Mathews, W. B., Ravert, H. T., Dannals, R. F., & Ricaurte, G. A. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300736 · Cited by 204
Estimating Hydroxyl Radical Content in Rat Brain Using Systemic and Intraventricular Salicylate: Impact of Methamphetamine
Giovanni, A., Liang, L., Hastings, T. G., & Zigmond, M. J. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64041819.x · Cited by 202
Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium
Harkness, K. A. (2000) · Brain · doi:10.1093/brain/123.4.698 · Cited by 195
Cytokines Regulate Gelatinase A and B (Matrix Metalloproteinase 2 and 9) Activity in Cultured Rat Astrocytes
Gottschall, P. E., & Yu, X. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.64041513.x · Cited by 192
Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines
Thomas, D. M., Dowgiert, J., Geddes, T. J., Francescutti, D. M., Liu, X., & Kuhn, D. M. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.065 · Cited by 192
Activation of murine microglial cell lines by lipopolysaccharide and interferon‐γ causes NO‐mediated decreases in mitochondrial and cellular function
Moss, D. W., & Bates, T. E. (2001) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2001.01418.x · Cited by 192
(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Clinical Studies
McCann, U. D., Eligulashvili, V., & Ricaurte, G. A. (2000) · Neuropsychobiology · doi:10.1159/000026665 · Cited by 190
Causes and consequences of methamphetamine and MDMA toxicity
Quinton, M. S., & Yamamoto, B. K. (2006) · The AAPS Journal · doi:10.1007/bf02854904 · Cited by 188
Self-citation
The Neuronal Nitric Oxide Synthase Inhibitor, 7‐Nitroindazole, Protects Against Methamphetamine‐Induced Neurotoxicity In Vivo
Itzhak, Y., & Ali, S. F. (1996) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1996.67041770.x · Cited by 184
Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine.
Stone, D. M., Johnson, M., Hanson, G. R., & Gibb, J. W. (1988) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20051-9 · Cited by 184
Role of Tumor Necrosis Factor-α in Methamphetamine-Induced Drug Dependence and Neurotoxicity
Nakajima, A., Yamada, K., Nagai, T., Uchiyama, T., Miyamoto, Y., Mamiya, T., He, J., Nitta, A., Mizuno, M., Tran, M. H., et al. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4847-03.2004 · Cited by 176
Monoamine oxidase, hydrogen peroxide, and Parkinson's disease.
Cohen, G. (1987) · PubMed · Cited by 173
High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus
Bowyer, J. F., & Ali, S. F. (2006) · Synapse · doi:10.1002/syn.20324 · Cited by 162
The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra
Fornstedt, B., Brun, A., Rosengren, E., & Carlsson, A. (1989) · Journal of Neural Transmission - Parkinsons Disease and Dementia Section · doi:10.1007/bf02263482 · Cited by 160
Increased production of gelatinase B (matrix metalloproteinase‐9) and interleukin‐6 by activated rat microglia in culture
Gottschall, P. E., Yu, X., & Bing, B. (1995) · Journal of Neuroscience Research · doi:10.1002/jnr.490420307 · Cited by 157
Parallel increases in lipid and protein oxidative markers in several mouse brain regions after methamphetamine treatment
Gluck, M. R., Moy, L. Y., Jayatilleke, E., Hogan, K. A., Manzino, L., & Sonsalla, P. K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00549.x · Cited by 153
Selective Blockade of mGlu5 Metabotropic Glutamate Receptors Is Protective against Methamphetamine Neurotoxicity
Battaglia, G., Fornai, F., Busceti, C. L., Aloisi, G., Cerrito, F., Blasi, A. D., Melchiorri, D., & Nicoletti, F. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-06-02135.2002 · Cited by 148
INVOLVEMENT OF OXIDATIVE STRESS IN 3-NITROPROPIONIC ACID NEUROTOXICITY
Schulz, J. B., Henshaw, D. R., MacGarvey, U. M., & Beal, M. F. (1996) · Neurochemistry International · doi:10.1016/0197-0186(95)00122-0 · Cited by 145
Rapid and transient inhibition of mitochondrial function following methamphetamine or 3,4-methylenedioxymethamphetamine administration
Burrows, K. B., Gudelsky, G. A., & Yamamoto, B. K. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00264-8 · Cited by 145
Self-citation
Methamphetamine‐Induced Changes in Antioxidant Enzymes and Lipid Peroxidation in Copper/Zinc‐Superoxide Dismutase Transgenic Mice
Jayanthi, S., Ladenheim, B., & Cadet, J. L. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb08224.x · Cited by 143
Rapid ATP Loss Caused by Methamphetamine in the Mouse Striatum: Relationship Between Energy Impairment and Dopaminergic Neurotoxicity
Chan, P., Monte, D. A. D., Luo, J. J., DeLanney, L. E., Irwin, I., & Langston, J. W. (1994) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1994.62062484.x · Cited by 141
Effect of antioxidant N-acetyl-l-cysteine on behavioral changes and neurotoxicity in rats after administration of methamphetamine
Fukami, G., Hashimoto, K., Koike, K., Okamura, N., Shimizu, E., & Iyo, M. (2004) · Brain Research · doi:10.1016/j.brainres.2004.04.072 · Cited by 137
Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells
Łazarewicz, J. W., Wroblewski, J. T., Palmer, M. E., & Costa, E. (1988) · Neuropharmacology · doi:10.1016/0028-3908(88)90088-3 · Cited by 137
MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity
Thomas, D. M., & Kuhn, D. M. (2005) · Brain Research · doi:10.1016/j.brainres.2005.05.049 · Cited by 132
Neurodegeneration in Striatum Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Role of Matrix Metalloproteinase-9 in Early Blood-Brain Barrier Disruption?
Kim, G. W., Gasche, Y., Grzeschik, S. M., Copin, J., Maier, C. M., & Chan, P. H. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08733.2003 · Cited by 131
Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6
Ladenheim, B., Krasnova, I. N., Deng, X., Oyler, J. M., Polettini, A., Moran, T. H., Huestis, M. A., & Cadet, J. L. (2000) · Molecular Pharmacology · doi:10.1124/mol.58.6.1247 · Cited by 131
Effects of GM-CSF and ordinary supplements on the ramification of microglia in culture: A morphometrical study
Fujita, H., Tanaka, J., Toku, K., Tateishi, N., Suzuki, Y., Matsuda, S., Sakanaka, M., & Maeda, N. (1996) · Glia · doi:10.1002/(sici)1098-1136(199612)18:4 · Cited by 128
Neurotoxicity in Dopamine and 5‐Hydroxytryptamine Terminal Fields: A Regional Analysis in Nigrostriatal and Mesolimbic Projections
Seiden, L. S., Commins, D., Vosmer, G. L., Axt, K. J., & Marek, G. J. (1988) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1988.tb42104.x · Cited by 126
Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons
Marek, G. J., Vosmer, G. L., & Seiden, L. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90467-p · Cited by 124
Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease
Jicha, G. A., Berenfeld, B., & Davies, P. J. (1999) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19990315)55:6 · Cited by 119
Developmental dissociation of methamphetamine-induced depletion of dopaminergic terminals and astrocyte reaction in rat striatum
Pu, C., & Vorhees, C. V. (1993) · Developmental Brain Research · doi:10.1016/0165-3806(93)90201-k · Cited by 119
Peroxynitrite Inactivation of Tyrosine Hydroxylase: Mediation by Sulfhydryl Oxidation, not Tyrosine Nitration
Kuhn, D. M., Aretha, C. W., & Geddes, T. J. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-23-10289.1999 · Cited by 115
The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits.
Sprague, J. E., & Nichols, D. E. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)09490-x · Cited by 115
Glial Fibrillary Acidic Protein
Vitry, F. D., Picart, R., Jacque, C., & Tixier‐Vidal, A. (2007) · Developmental Neuroscience · doi:10.1159/000112813 · Cited by 114
Dopamine Quinones Activate Microglia and Induce a Neurotoxic Gene Expression Profile
Kuhn, D. M., Francescutti‐Verbeem, D. M., & Thomas, D. M. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1369.003 · Cited by 111
The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge
Ben-Shaul, V., Lomnitski, L., Nyska, A., Zurovsky, Y., Bergman, M., & Grossman, S. (2001) · Toxicology Letters · doi:10.1016/s0378-4274(01)00369-1 · Cited by 110
Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX.
Farfel, G. M., & Seiden, L. S. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24411-1 · Cited by 110
Role of hypothermia in the mechanism of protection against serotonergic toxicity. II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan.
Farfel, G. M., & Seiden, L. S. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24505-0 · Cited by 109
The spin trap reagent α-phenyl-N-tert-butylnitrone prevents ‘ecstasy’-induced neurodegeneration of 5-hydroxytryptamine neurones
Colado, M. I., & Green, A. R. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00298-y · Cited by 105
Methamphetamine‐induced inhibition of mitochondrial complex II: roles of glutamate and peroxynitrite
Brown, J. M., Quinton, M. S., & Yamamoto, B. K. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03379.x · Cited by 103
Self-citation
In vivo neutralization of endogenous brain fractalkine increases hippocampal TNFα and 8-isoprostane production induced by intracerebroventricular injection of LPS
Zujovic, V., Schussler, N., Jourdain, D., Duverger, D., & Taupin, V. (2001) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(01)00259-4 · Cited by 102
[18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses
Mulholland, G. K., Wieland, D. M., Kilbourn, M. R., Frey, K. A., Sherman, P. S., Carey, J. E., & Kuhl, D. E. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199811)30:3 · Cited by 100
Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA
Schmued, L. C. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02563-0 · Cited by 100
Causes and Consequences of Methamphetamine and MDMA Toxicity
Quinton, M. S., & Yamamoto, B. K. (2006) · The AAPS Journal · doi:10.1208/aapsj080238 · Cited by 99
Self-citation
Overexpression of human copper/zinc superoxide dismutase in transgenic mice attenuates oxidative stress caused by methylenedioxymethamphetamine (Ecstasy)
Jayanthi, S., Ladenheim, B., Andrews, A. M., & Cadet, J. L. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00698-8 · Cited by 90
Substrates of Energy Metabolism Attenuate Methamphetamine‐Induced Neurotoxicity in Striatum
Stephans, S. E., Whittingham, T. S., Douglas, A., Lust, W. D., & Yamamoto, B. K. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.71020613.x · Cited by 90
Self-citation
A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine
Eyerman, D. J., & Yamamoto, B. K. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04837.x · Cited by 87
Self-citation
Protease production by cultured microglia: Substrate gel analysis and immobilized matrix degradation
Colton, C. A., Keri, J. E., Chen, W. T., & Monsky, W. L. (1993) · Journal of Neuroscience Research · doi:10.1002/jnr.490350309 · Cited by 84
Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine
Schmidt, C. J., Black, C. K., & Taylor, V. L. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)90245-2 · Cited by 82
Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): Evidence from using CuZn‐superoxide dismutase transgenic mice
Cadet, J. L., Ladenheim, B., Hirata, H., Rothman, R. B., Ali, S. F., Carlson, E. J., Epstein, C. J., & Moran, T. H. (1995) · Synapse · doi:10.1002/syn.890210210 · Cited by 81
Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies
Ryu, J. K., Nagai, A., Kim, J., Lee, M. C., McLarnon, J. G., & Kim, S. U. (2003) · Neurobiology of Disease · doi:10.1016/s0969-9961(03)00002-0 · Cited by 81
3,4‐Methylenedioxymethamphetamine increases interleukin‐1β levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5‐HT depletion
Orío, L., O’Shea, E., Sánchez, V., Pradillo, J. M., Escobedo, I., Camarero, J., Moro, M. Á., Green, A. R., & Colado, M. I. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02443.x · Cited by 80
Pretreatment with ascorbic acid attenuates the neurotoxic effects of methamphetamine in rats.
Wagner, G. C., Carelli, R. M., & Jarvis, M. F. (1985) · PubMed · Cited by 80
Acute inactivation of tryptophan hydroxylase by amphetamine analogs involves the oxidation of sulfhydryl sites
Stone, D. M., Johnson, M., Hanson, G. R., & Gibb, J. W. (1989) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(89)90048-5 · Cited by 80
Microgliosis and down-regulation of adenosine transporter induced by methamphetamine in rats
Escubedo, E., Guitart, L., Sureda, F. X., Jiménez, A., Pubill, D., Pallàs, M., Camins, A., & Camarasa, J. (1998) · Brain Research · doi:10.1016/s0006-8993(98)01065-8 · Cited by 79
Methamphetamine-induced neurotoxicity in mouse brain is attenuated by ketoprofen, a non-steroidal anti-inflammatory drug
Asanuma, M., Tsuji, T., Miyazaki, I., Miyoshi, K., & Ogawa, N. (2003) · Neuroscience Letters · doi:10.1016/j.neulet.2003.08.015 · Cited by 77
Reduction of methamphetamine‐induced sensitization and reward in matrix metalloproteinase‐2 and ‐9‐deficient mice
Mizoguchi, H., Yamada, K., Niwa, M., Mouri, A., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y., & Nabeshima, T. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04288.x · Cited by 75
Peroxynitrite Inactivates Tryptophan Hydroxylase via Sulfhydryl Oxidation
Kuhn, D. M., & Geddes, T. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.42.29726 · Cited by 75
Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst
Imam, S. Z., Crow, J. P., Newport, G. D., Islam, F., Slikker, W., & Ali, S. F. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01663-7 · Cited by 73
Neurochemical basis of neurotoxicity.
Gibb, J. W., Johnson, M., & Gr, H. (1990) · PubMed · Cited by 72
Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine‐induced behavioral sensitization and reward: implications for dopamine receptor down‐regulation and dopamine release
Mizoguchi, H., Yamada, K., Mouri, A., Niwa, M., Mizuno, T., Noda, Y., Nitta, A., Itohara, S., Banno, Y., & Nabeshima, T. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04623.x · Cited by 71
Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain
Zhang, L., Shirayama, Y., Shimizu, E., Iyo, M., & Hashimoto, K. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.05.047 · Cited by 71
Acute neuropathological changes in the caudate nucleus caused by MPTP and methamphetamine: Immunohistochemical studies
Hess, A., Desiderio, C., & McAuliffe, W. G. (1990) · Journal of Neurocytology · doi:10.1007/bf01188403 · Cited by 71
Acute systemic inflammation induces central mitochondrial damage and mnesic deficit in adult Swiss mice
Noble, F., Rubira, E., Boulanouar, M., Palmier, B., Plotkine, M., Warnet, J., Marchand‐Leroux, C., & Massicot, F. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.07.005 · Cited by 70
Mazindol Attenuates the 3,4‐Methylenedioxymethamphetamine‐Induced Formation of Hydroxyl Radicals and Long‐Term Depletion of Serotonin in the Striatum
Shankaran, M., Yamamoto, B. K., & Gudelsky, G. A. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0722516.x · Cited by 69
Self-citation
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB
Barhoumi, R., Faske, J. B., Liu, X., & Tjalkens, R. B. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2003.12.009 · Cited by 68
Methamphetamine-induced expression of interleukin-1β mRNA in the rat hypothalamus
Yamaguchi, T., Kuraishi, Y., Minami, M., Nakai, S., Hirai, Y., & Satoh, M. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90766-m · Cited by 65
(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates
Ricaurte, G. A. (1988) · JAMA · doi:10.1001/jama.260.1.51 · Cited by 65
Concurrent calpain and caspase-3 mediated proteolysis of αII-spectrin and tau in rat brain after methamphetamine exposure: A similar profile to traumatic brain injury
Warren, M. W., Kobeissy, F. H., Liu, M. C., Hayes, R. L., Gold, M. S., & Wang, K. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.04.058 · Cited by 64
Methamphetamine treatment rapidly inhibits serotonin, but not glutamate, transporters in rat brain
Kokoshka, J. M., Metzger, R. R., Wilkins, D. G., Gibb, J. W., Hanson, G. R., & Fleckenstein, A. E. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00472-7 · Cited by 62
L-DOPA potentiation of the serotonergic deficits due to a single administration of 3,4-methylenedioxymethamphetamine, p-chloroamphetamine or methamphetamine to rats
Schmidt, C. J., Black, C. K., & Taylor, V. L. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90788-r · Cited by 61
Induction of endothelial cell apoptosis by lipid hydroperoxide-derived bifunctional electrophiles
Jian, W., Arora, J. S., Oe, T., Shuvaev, V. V., & Blair, I. A. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.06.008 · Cited by 60
A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke
Bowler, R. P., Sheng, H., Enghild, J. J., Pearlstein, R. D., Warner, D. S., & Crapo, J. D. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01008-0 · Cited by 60
Cyclooxygenase-2 Is an Obligatory Factor in Methamphetamine-Induced Neurotoxicity
Thomas, D. M., & Kuhn, D. M. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.080242 · Cited by 58
Methamphetamine‐induced spectrin proteolysis in the rat striatum
Staszewski, R., & Yamamoto, B. K. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03618.x · Cited by 57
Self-citation
Effect of ascorbate and cysteine on the 3,4-methylenedioxymethamphetamine-induced depletion of brain serotonin
Gudelsky, G. A. (1996) · Journal of Neural Transmission · doi:10.1007/bf01271253 · Cited by 57
Enhancement of 3,4‐methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate
Nixdorf, W. L., Burrows, K. B., Gudelsky, G. A., & Yamamoto, B. K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00262.x · Cited by 57
Self-citation
Central Administration of Methamphetamine Synergizes with Metabolic Inhibition to Deplete Striatal Monoamines
Burrows, K. B., Nixdorf, W. L., & Yamamoto, B. K. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35363-7 · Cited by 57
Self-citation
Effects of repeated systemic administration of d -Fenfluramine on serotonin and glutamate release in rat ventral hippocampus: comparison with methamphetamine using in vivo microdialysis
Available, N. A. N., & Available, N. A. N. (2001) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s002100000381 · Cited by 55
Metabolic mapping of the effects of intravenous methamphetamine administration in freely moving rats
Pontieri, F. E., Crane, A. M., Seiden, L. S., Kleven, M. S., & Porrino, L. J. (1990) · Psychopharmacology · doi:10.1007/bf02245919 · Cited by 54
Evidence for the Involvement of Nitric Oxide in 3,4-Methylenedioxymethamphetamine-Induced Serotonin Depletion in the Rat Brain
Darvesh, A. S., Yamamoto, B. K., & Gudelsky, G. A. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.074849 · Cited by 53
Self-citation
Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat
Bémeur, C., Ste‐Marie, L., Desjardins, P., Vachon, L., Butterworth, R. F., Hazell, A. S., & Montgomery, J. A. (2005) · Neurochemistry International · doi:10.1016/j.neuint.2004.11.007 · Cited by 53
Effects of a high-dose treatment of methamphetamine on caudate dopamine and anorexia in rats
Bittner, S. E., Wagner, G. C., Aigner, T. G., & Seiden, L. S. (1981) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(81)90306-3 · Cited by 52
Prevention of Dopaminergic Neurotoxicity by Targeting Nitric Oxide and Peroxynitrite: Implications for the Prevention of Methamphetamine‐induced Neurotoxic Damage
Imam, S. Z., Islam, F., Itzhak, Y., SLIKKER, W., & Ali, S. F. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05193.x · Cited by 50
The N-methyl-d-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine 3,4-methylenedioxymethamphetamine and p-chloroamphetamine
Farfel, G. M., Vosmer, G. L., & Seiden, L. S. (1992) · Brain Research · doi:10.1016/0006-8993(92)91460-v · Cited by 49
Calpain- and caspase-mediated αII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure
Warren, M. W., Zheng, W., Kobeissy, F. H., Liu, M. C., Hayes, R. L., Gold, M. S., Larner, S. F., & Wang, K. (2006) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145706007061 · Cited by 49
Acute methylenedioxymethamphetamine administration: effects on local cerebral blood flow and glucose utilisation in the dark agouti rat
Quate, L., McBean, D. E., Ritchie, I. M., Olverman, H. J., & Kelly, P. A. T. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1784-z · Cited by 47
Neuropsychotoxicity of Abused Drugs: Involvement of Matrix Metalloproteinase-2 and -9 and Tissue Inhibitor of Matrix Metalloproteinase-2 in Methamphetamine-Induced Behavioral Sensitization and Reward in Rodents
Mizoguchi, H., Yamada, K., & Nabeshima, T. (2008) · Journal of Pharmacological Sciences · doi:10.1254/jphs.fm0070139 · Cited by 44
Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT
Darvesh, A. S., & Gudelsky, G. A. (2005) · Brain Research · doi:10.1016/j.brainres.2005.07.009 · Cited by 44
Methamphetamine-induced striatal dopamine neurotoxicity and cyclooxygenase-2 protein expression in BALB/c mice
Kita, T., Shimada, K., Mastunari, Y., Wagner, G. C., Kubo, K., & Nakashima, T. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(99)00175-6 · Cited by 41
Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats
Sanchez, V. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(02)00411-2 · Cited by 40
L-Tyrosine Contributes to (+)-3,4-Methylenedioxymethamphetamine-Induced Serotonin Depletions
Breier, J. M., Bankson, M. G., & Yamamoto, B. K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3353-05.2006 · Cited by 40
Self-citation
Antioxidant eugenosedin-A protects against lipopolysaccharide-induced hypotension, hyperglycaemia and cytokine immunoreactivity in rats and mice
Shen, K., Lo, Y., Yang, R., Liu, H., Chen, I., & Wu, B. (2004) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357055137 · Cited by 40
An antisense oligonucleotide targeted at MAO-B attenuates rat striatal serotonergic neurotoxicity induced by MDMA
Falk, E. M., Cook, V. J., Nichols, D. E., & Sprague, J. E. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00728-1 · Cited by 39
3,4-Methylenedioxymethamphetamine Produces Glycogenolysis and Increases the Extracellular Concentration of Glucose in the Rat Brain
Darvesh, A. S., Shankaran, M., & Gudelsky, G. A. (2002) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.301.1.138 · Cited by 37
The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells
Liu, X., Wu, J., Zhou, F., Sun, X., Yao, H., Yang, Y., Ding, J., & Hu, G. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.10.018 · Cited by 36
Molecular Footprints of Neurotoxic Amphetamine Action
Kuhn, D. M., & Geddes, T. J. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05187.x · Cited by 34
Matrix Metalloproteinases in Neuroinflammation and Cerebral Ischemia
Rosenberg, G. A., & Mun-Bryce, S. (2004) · Springer eBooks · doi:10.1007/978-3-662-05426-0_1 · Cited by 32
Inactivation of Tryptophan Hydroxylase by Nitric Oxide: Enhancement by Tetrahydrobiopterin
Kuhn, D. M., & Arthur, R. E. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.68041495.x · Cited by 29
Effects of Repeated High-Dose Methamphetamine on Local Cerebral Glucose Utilization in Rats
Huang, Y. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00029-9 · Cited by 28
The effect of amphetamine analogs on cleaved microtubule-associated protein-tau formation in the rat brain
Straiko, M. M. W., Coolen, L. M., Zemlan, F. P., & Gudelsky, G. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.073 · Cited by 27
Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum
Sprague, J. E., & Nichols, D. E. (1995) · Psychopharmacology · doi:10.1007/bf02245967 · Cited by 27
3,4-Methylenedioxymethamphetamine increases pro-interleukin-1β production and caspase-1 protease activity in frontal cortex, but not in hypothalamus, of Dark Agouti rats: Role of interleukin-1β in neurotoxicity
O’Shea, E., Sanchez, V., Orío, L., Escobedo, I., Green, A. R., & Colado, M. I. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.06.084 · Cited by 24
Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats
Zhang, X., Dong, F., Mayer, G. E., Bruch, D. C., Ren, J. T., & Culver, B. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.09.059 · Cited by 22
Continuous amphetamine administration induces tyrosine hydroxylase immunoreactive patches in the adult rat neostriatum
Ryan, L. J., Martone, M. E., Linder, J. C., & Groves, P. M. (1988) · Brain Research Bulletin · doi:10.1016/0361-9230(88)90129-3 · Cited by 21

Sorted by citations

Toxicity of amphetamines: an update
Carvalho, M. C., Carmo, H., Costa, V. M., Capela, J. P., Pontes, H., Remião, F., Carvalho, F. D., & Bastos, M. D. L. (2012) · Archives of Toxicology · doi:10.1007/s00204-012-0815-5 · Cited by 449
Cytokines mediated inflammation and decreased neurogenesis in animal models of depression
Song, C., & Wang, H. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.020 · Cited by 297
Amphetamine toxicities
Yamamoto, B. K., Moszczyńska, A., & Gudelsky, G. A. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05141.x · Cited by 289
Self-citation
The Effects of Psychostimulant Drugs on Blood Brain Barrier Function and Neuroinflammation
Kousik, S. M., Napier, T. C., & Carvey, P. M. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00121 · Cited by 180
Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse
Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148

See all 167

Authors: Yamamoto, B. K., & Raudensky, J.
Affiliations: Boston University (US)
Corresponding author: Yamamoto, Bryan K.
ORCID: Yamamoto, Bryan K.
Venue: Journal of Neuroimmune Pharmacology
Publisher: Springer Science and Business Media LLC
Published: 2008-08-15
Volume: 3
Issue: 4
Pages: 203-217
ISSN: 1557-1890 (ISSN-L)
1557-1904
DOI: 10.1007/s11481-008-9121-7
PMC: PMC3955110
OpenAlex: W2135980918
Cited by: 167
References: 168
Citations by year: 2026: 5 · 2025: 12 · 2024: 6 · 2023: 6 · 2022: 18 · 2021: 10 · 2020: 8 · 2019: 4 · 2018: 7 · 2017: 10 · 2016: 10 · 2015: 8 · 2014: 12 · 2013: 12 · 2012: 16
FWCI: 1.09
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Journal of Neuroimmune Pharmacology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Drug Abuse (R01DA007606)
Topics: Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
Keywords: methamphetamine, MDMA, ecstasy, oxidative stress, mitochondrial dysfunction, neuroinflammation, dopaminergic neurons, serotonergic neurons, neuronal injury, neurotoxicity, drug abuse
MeSH terms: Amphetamines, Animals, Brain, Humans, Inflammation, Neurons, Illicit Drugs, Oxidative Stress

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Role of Oxidative Stress, Metabolic Compromise, and Inflammation in Neuronal Injury Produced by Amphetamine-Related Drugs of Abuse

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks