Mouse models of neurodegenerative disease: preclinical imaging and neurovascular component

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

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Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

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Applications of the Morris water maze in the study of learning and memory

D’Hooge, R., & Deyn, P. P. D. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00067-4 · Cited by 2,035 · see citing works

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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UNRAVELING THE MECHANISMS INVOLVED IN MOTOR NEURON DEGENERATION IN ALS

Bruijn, L. I., Miller, T. M., & Cleveland, D. W. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144244 · Cited by 1,371 · see citing works

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer’s Disease

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Cerebral amyloid angiopathy. A critical review.

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Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

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Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

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Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease

Oddo, S. (2003) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2003.08.012 · Cited by 980 · see citing works

Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers

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The genetic landscape of Alzheimer disease: clinical implications and perspectives

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Alzheimer disease and cerebrovascular pathology: an update

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Animal models of Parkinson's disease

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VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

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Drug Design, Development and Therapy

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Targeting Angiogenesis in Cancer Therapy: Moving Beyond Vascular Endothelial Growth Factor

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Aβ toxicity in Alzheimer’s disease: globular oligomers (ADDLs) as new vaccine and drug targets

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VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

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Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein

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ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

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A delicate balance: Iron metabolism and diseases of the brain

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Animal models of Parkinson’s disease

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Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss

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Experimental Autoimmune Encephalomyelitis in the Mouse

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Spatial navigational strategies correlate with gray matter in the hippocampus of healthy older adults tested in a virtual maze

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Assessment of Motor Balance and Coordination in Mice using the Balance Beam

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Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy

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Animal models of Multiple Sclerosis

Procaccini, C., Rosa, V. D., Pucino, V., Formisano, L., & Matarese, G. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.03.042 · Cited by 371 · see citing works

Transgenic mouse models of Alzheimer’s disease.

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Mouse models of Alzheimer's disease

Hall, A. M., & Roberson, E. D. (2012) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2011.11.017 · Cited by 317 · see citing works

Cognitive Dysfunction Precedes Neuropathology and Motor Abnormalities in the YAC128 Mouse Model of Huntington's Disease

Raamsdonk, J. M. V., Pearson, J., Slow, E., Hossain, S. M., Leavitt, B. R., & Hayden, M. R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0590-05.2005 · Cited by 315 · see citing works

Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis

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Theiler's Virus Infection: a Model for Multiple Sclerosis

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PIB is a non-specific imaging marker of amyloid-beta (A ) peptide-related cerebral amyloidosis

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Age‐dependent cognitive decline in the APP23 model precedes amyloid deposition

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Curcumin-conjugated magnetic nanoparticles for detecting amyloid plaques in Alzheimer's disease mice using magnetic resonance imaging (MRI)

Cheng, K. K., Chan, P. S., Fan, S., Kwan, S. M., Yeung, K. L., Wáng, Y. X. J., Chow, A. H. L., Wu, E. X., & Baum, L. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2014.12.005 · Cited by 293 · see citing works

Cerebrovascular and blood–brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

Drouin‐Ouellet, J., Sawiak, S. J., Cisbani, G., Lagacé, M., Kuan, W., Saint‐Pierre, M., Dury, R. J., Alata, W., St‐Amour, I., Mason, S. L., et al. (2015) · Annals of Neurology · doi:10.1002/ana.24406 · Cited by 288 · see citing works

Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior

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Nonmotor Symptoms of Parkinson's Disease Revealed in an Animal Model with Reduced Monoamine Storage Capacity

Taylor, T. N., Caudle, W. M., Shepherd, K. R., Noorian, A. R., Jackson, C. R., Iuvone, P. M., Weinshenker, D., Greene, J. G., & Miller, G. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1495-09.2009 · Cited by 278 · see citing works

Molecular SPECT Imaging: An Overview

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Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

Ryu, J. K., Petersen, M. A., Murray, S. G., Baeten, K. M., Meyer-Franke, A., Chan, J. P., Vagena, E., Bedard, C., Machado, M. R., Coronado, P. E. R., et al. (2015) · Nature Communications · doi:10.1038/ncomms9164 · Cited by 271 · see citing works

Age-dependent Motor Deficits and Dopaminergic Dysfunction in DJ-1 Null Mice

Chen, L., Cagniard, B., Mathews, T. A., Jones, S. R., Koh, H. C., Ding, Y., Carvey, P. M., Ling, Z., Kang, U. J., & Zhuang, X. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413955200 · Cited by 261 · see citing works

Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice

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Noninvasive Molecular Imaging of Neuroinflammation

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The Big Idea: Iron-Dependent Inflammation in Venous Disease and Proposed Parallels in Multiple Sclerosis

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Animal Models of Huntington's Disease

Ramaswamy, S., McBride, J. L., & Kordower, J. H. (2007) · ILAR Journal · doi:10.1093/ilar.48.4.356 · Cited by 234 · see citing works

Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: A role for intraneuronal amyloid

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Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons

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Early formation of mature amyloid‐β protein deposits in a mutant APP transgenic model depends on levels of Aβ1–42

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Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease

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Molecular Targeting of Alzheimer's Amyloid Plaques for Contrast-Enhanced Magnetic Resonance Imaging

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Olfactory deficits in mice overexpressing human wildtype α‐synuclein

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Mouse Models of Multiple Sclerosis: Experimental Autoimmune Encephalomyelitis and Theiler’s Virus-Induced Demyelinating Disease

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Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl‐ 11 C]‐2‐(4′‐methylaminophenyl)‐ 6‐hydroxybenzothiazole

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ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood–Brain Barrier for Aβ 1–40 Peptides

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Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

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Alpha-synuclein and transgenic mouse models

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Behavioral phenotyping of mouse models of Parkinson's disease

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Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis

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Behavioral and histopathological consequences of paraquat intoxication in mice: Effects of α‐synuclein over‐expression

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Modeling PD pathogenesis in mice: Advantages of a chronic MPTP protocol

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The inflammatory response in the MPTP model of Parkinson’s disease is mediated by brain angiotensin: relevance to progression of the disease

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A New Mouse Mutant with Progressive Motor Neuronopathy

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Dense-Core Plaques in Tg2576 and PSAPP Mouse Models of Alzheimer's Disease Are Centered on Vessel Walls

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Regular exercise is beneficial to a mouse model of amyotrophic lateral sclerosis

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Parkinson’s disease: genetic versus toxin‐induced rodent models

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Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice

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Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

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Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease

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Changes in dopamine levels in the corpus striatum following lesions in the substantia nigra

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Automated deformation analysis in the YAC128 Huntington disease mouse model

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Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease

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Effects of commissural de- and remyelination on motor skill behaviour in the cuprizone mouse model of multiple sclerosis

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A partial lesion model of Parkinson's disease in mice – Characterization of a 6-OHDA-induced medial forebrain bundle lesion

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Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation

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Longitudinal Evaluation of theHdh(CAG)150Knock-In Murine Model of Huntington's Disease

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A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions

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Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease

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Rodent genetic models of Huntington disease

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Age-Dependent Cerebrovascular Abnormalities and Blood Flow Disturbances in APP23 Mice Modeling Alzheimer's Disease

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Characterization of relapsing–remitting and chronic forms of experimental autoimmune encephalomyelitis in C57BL/6 mice

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Novel Object Recognition as a Facile Behavior Test for Evaluating Drug Effects in AβPP/PS1 Alzheimer's Disease Mouse Model

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Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

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Additional file 1 of Control of the temporal development of Alzheimer’s disease pathology by the MR1/MAIT cell axis

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