CoChat
Sign Up
Cited by 1,010Ovarian function and disordersDiabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Function and Risk Factors

Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with the Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society

Wild, Robert A., Carmina, Enrico, Diamanti-Kandarakis, Evanthia, Dokras, Anuja, Escobar-Morreale, Hector F., Futterweit, Walter, Lobo, Rogerio, Norman, Robert J. +2 more·2010·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jc.2009-2724
Open this paper in CoChat — free account

Abstract

OBJECTIVE: Women with polycystic ovary syndrome (PCOS) often have cardiovascular disease (CVD) risk factors. The Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society created a panel to provide evidence-based reviews of studies assessing PCOS-CVD risk relationships and to develop guidelines for preventing CVD. PARTICIPANTS: An expert panel in PCOS and CVD reviewed literature and presented recommendations. EVIDENCE: Only studies comparing PCOS with control patients were included. All electronic databases were searched; reviews included individual studies/databases, systematic reviews, abstracts, and expert data. Articles were excluded if other hyperandrogenic disorders were not excluded, PCOS diagnosis was unclear, controls were not described, or methodology precluded evaluation. Inclusion/exclusion criteria were confirmed by at least two reviewers and arbitrated by a third. CONSENSUS PROCESS: Systematic reviews of CVD risk factors were compiled and submitted for approval to the AE-PCOS Society Board. CONCLUSIONS: Women with PCOS with obesity, cigarette smoking, dyslipidemia, hypertension, impaired glucose tolerance, and subclinical vascular disease are at risk, whereas those with metabolic syndrome and/or type 2 diabetes mellitus are at high risk for CVD. Body mass index, waist circumference, serum lipid/glucose, and blood pressure determinations are recommended for all women with PCOS, as is oral glucose tolerance testing in those with obesity, advanced age, personal history of gestational diabetes, or family history of type 2 diabetes mellitus. Mood disorder assessment is suggested in all PCOS patients. Lifestyle management is recommended for primary CVD prevention, targeting low-density and non-high-density lipoprotein cholesterol and adding insulin-sensitizing and other drugs if dyslipidemia or other risk factors persist.

Integrity signals

Registry

Crossref · 10.1210/jc.2009-2724

Cites

143 of 143 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • We did not identify high-quality PCOS-specific evidence to answer the question, hence a clinical consensus recommendation was made based on clinical expertise, an international position statement on CVD risk assessment in PCOS and on national guidelines on absolute CVD risk assessment, management of obesity, lipids and hypertension for the general population.

    “We did not identify high-quality PCOS-specific evidence to answer the question, hence a clinical consensus recommendation was made based on clinical expertise, an international position statement on CVD risk assessment in PCOS 78 and on national guidelines on absolute CVD risk assessment, 46 management of obesity, 54 lipids 77,79 and hypertension 80 for the general population.”

    From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [78]

  • Previous studies have noted that fasting blood glucose level alone appears to lack sensitivity in screening for prediabetes or DM2 in PCOS, with national and international groups recommending screening all women with PCOS with an OGTT.

    “Previous studies have noted that fasting blood glucose level alone appears to lack sensitivity in screening for prediabetes or DM2 in PCOS, with national and international groups recommending screening all women with PCOS with an OGTT. 78,107”

    From Assessment and management of polycystic ovary syndrome: Summary of an evidence-based guideline (2011) · cites this paper as [78]

Cites

1 retracted

Flagged first, then by citations

3 of the 146 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Wild, R. A., Carmina, E., Diamanti-Kandarakis, E., Dokras, A., Escobar-Morreale, H. F., Futterweit, W., Lobo, R., Norman, R. J., Talbott, E., & Dumesic, D. A.
Affiliations
  • OU Health (US)
  • University of Palermo (IT)
  • University of Athens Medical School (E.D.-K.), 11527 Athens, Greece
  • University of Pennsylvania (US)
  • Hospital Ramon y Cajal (H.F.E.-M.), 28034 Madrid, Spain
  • Icahn School of Medicine at Mount Sinai (US)
  • Columbia University (R.L.), New York, New York 10027
  • The University of Adelaide (AU)
  • University of Pittsburgh (US)
  • University of Wisconsin–Madison (US)
Corresponding author
Carmina, Enrico
ORCID
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
2010-05-01
Volume
95
Issue
5
Pages
2038-2049
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jc.2009-2724
OpenAlex
W2105749473
Semantic Scholar
5556ce96457d5a9ef1f00894a9f61047e5c6afb4
Cited by
1,010
References
146
Citations by year
2026: 34 · 2025: 47 · 2024: 45 · 2023: 62 · 2022: 77 · 2021: 52 · 2020: 56 · 2019: 73 · 2018: 61 · 2017: 58 · 2016: 62 · 2015: 89 · 2014: 85 · 2013: 69 · 2012: 62
FWCI
79.63
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords
polycystic ovary syndrome, cardiovascular risk, cardiovascular disease prevention, hyperandrogenism, obesity, dyslipidemia, hypertension, impaired glucose tolerance, metabolic syndrome, type 2 diabetes, subclinical vascular disease, body mass index, waist circumference, oral glucose tolerance test, mood disorders, lifestyle management, insulin-sensitizing drugs, cardiovascular risk assessment
MeSH terms
Cardiovascular Diseases, Diabetes Mellitus, Type 2, Female, Humans, Polycystic Ovary Syndrome, Risk Factors, Body Mass Index, Glucose Intolerance, Risk Assessment, Waist-Hip Ratio, Atherosclerosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review