The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Glutamate and GABA Imbalance Following Traumatic Brain Injury
Open accessAbstract
Traumatic brain injury (TBI) leads to multiple short- and long-term changes in neuronal circuits that ultimately conclude with an imbalance of cortical excitation and inhibition. Changes in neurotransmitter concentrations, receptor populations, and specific cell survival are important contributing factors. Many of these changes occur gradually, which may explain the vulnerability of the brain to multiple mild impacts, alterations in neuroplasticity, and delays in the presentation of posttraumatic epilepsy. In this review, we provide an overview of normal glutamate and GABA homeostasis and describe acute, subacute, and chronic changes that follow injury. We conclude by highlighting opportunities for therapeutic interventions in this paradigm.
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Weis, C. N., Webb, E. K., deRoon-Cassini, T. A., & Larson, C. L. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.07.023 · Cited by 75
Understanding individual variability in symptoms and recovery following mTBI: a role for TMS-EEG
Coyle, H. L., Ponsford, J., & Hoy, K. E. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.05.027 · Cited by 21
Rlip76: An Unexplored Player in Neurodegeneration and Alzheimer’s Disease?
Hindle, A., Singh, S. P., Pradeepkiran, J. A., Bose, C., Vijayan, M., Kshirsagar, S., Sawant, N. A., & Reddy, P. H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116098 · Cited by 14
Metadata
- Authors
- Guerriero, R. M., Giza, C. C., & Rotenberg, A.
- Venue
- Current Neurology and Neuroscience Reports
- Published
- 2015-03-22
- Volume
- 15
- Issue
- 5
- Pages
- 27-27
- ISSN
- 1528-4042 (ISSN-L)
- 1534-6293
- OpenAlex
- W2003760083
- Cited by
- 463
- References
- 16
- FWCI
- 14.17
- Type
- journal article
- Language
- en
- Open access
- green
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