Anhedonia in schizophrenia
Abstract
This review highlights key issues and recent progress in understanding the epidemiology, phenomenology, etiology, and treatment of anhedonia in schizophrenia. A reduced pleasure capacity has been recognized as an important feature of the illness since the time of Kraepelin and Bleuler. However, it remains poorly understood for many reasons, including the phenotypic heterogeneity of schizophrenia, the multidimensionality and multifactorial etiology of anhedonia, and the difficulties inherent in the scientific analysis of subjective emotional experiences. We do know that anhedonia is common in schizophrenia, that it has significant negative consequences, and that current treatments are insufficient. Better assessment tools, greater understanding of biological and psychosocial mechanisms, and novel pharmacologic and psychosocial interventions are sorely needed. Anhedonia has received increasing attention in recent years, and there is optimism that the new Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative on negative symptoms will catalyze rapid progress in the near future.
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Anhedonia (diminished 'liking') is a less prominent feature of schizophrenia than avolition (diminished 'wanting').
“Several authoritative reviews thus concluded that anhedonia (diminished ‘liking’) is a less prominent feature of schizophrenia than avolition (diminished ‘wanting’) [49,51-53].”
From Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications (2012) · cites this paper as [53]
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- Authors
- Wolf, D. H.
- Affiliations
- University of Pennsylvania (US)
- Corresponding author
- Wolf, Daniel H.
- ORCID
- Wolf, Daniel H.
- Venue
- Current Psychiatry Reports
- Published
- 2006-07
- Volume
- 8
- Issue
- 4
- Pages
- 322-328
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- OpenAlex
- W2051023649
- Cited by
- 66
- References
- 50
- Citations by year
- 2023: 4 · 2022: 2 · 2021: 3 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 5 · 2015: 6 · 2014: 4 · 2013: 6 · 2012: 7
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- National Institutes of Health
- National Institute of Mental Health (T32MH019112)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- anhedonia, schizophrenia, negative symptoms, pleasure, etiology, treatment, phenomenology, psychosocial interventions, pharmacological interventions, assessment instruments, MATRICS
- MeSH terms
- Cognition Disorders, Humans, Schizophrenia, Schizophrenic Psychology, Antipsychotic Agents, Dopamine Antagonists, Mood Disorders, Dopamine D2 Receptor Antagonists
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