Insomnia as a Precipitating Factor in New Onset Mental Illness: a Systematic Review of Recent Findings
Abstract
Purpose We aimed to systematically review recent publications (01/2014-03/2017) with longitudinal designs allowing for the assessment of the prospective risk of insomnia on new onset mental illness in key conditions: anxiety, depression, bipolar disorder, posttraumatic stress disorder, substance use disorders, and suicide.Recent findings A literature yielded 1859 unique articles meeting search criteria were identified; 16 articles met all selection criteria and reviewed with some studies reporting on more than one mental health outcome. Overall, the review supports the hypothesis that insomnia is a predictor of subsequent mental illness. The evidence is strongest for an insomnia-depression relationship. The new studies identified and reviewed add to a modest number of publications supporting a prospective role of insomnia in new onset mental illness in three areas: anxiety disorders, bipolar disorder, and suicide. The few selected new studies focused on SUD were mixed, and no studies focused on PTSD were identified that met the selection criteria. Treatment of insomnia may also be a preventive mental health strategy.
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There is good evidence that insomnia increases the risk for depression, hypertension, and type 2 diabetes.
“There is good evidence that insomnia increases the risk for certain disorders including depression (439), hypertension (31), and type 2 diabetes (561)”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [439]
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- Authors
- Pigeon, W. R., Bishop, T. M., & Krueger, K. M.
- Affiliations
- University of Rochester Medicine (US)
- Canandaigua VA Medical Center (US)
- Corresponding author
- Pigeon, Wilfred R.
- Venue
- Current Psychiatry Reports
- Published
- 2017-06-14
- Volume
- 19
- Issue
- 8
- Pages
- 44-44
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- OpenAlex
- W2625391076
- Cited by
- 233
- References
- 82
- Citations by year
- 2026: 11 · 2025: 32 · 2024: 21 · 2023: 30 · 2022: 36 · 2021: 36 · 2020: 21 · 2019: 29 · 2018: 11 · 2017: 6
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- insomnia, depression, anxiety disorders, bipolar disorder, suicide, substance use disorders, post-traumatic stress disorder, insomnia treatment, mental health prevention
- MeSH terms
- Anxiety Disorders, Mental Disorders, Bipolar Disorder, Depressive Disorder, Humans, Sleep Initiation and Maintenance Disorders, Longitudinal Studies, Prospective Studies, Risk Factors, Stress Disorders, Post-Traumatic, Suicide, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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