Cited by 347Muscle metabolism and nutritionSports Performance and TrainingCardiovascular and exercise physiology

The DOI matches its Crossref record; 192 of the 192 references it cites were found in a registry or an index.

Interference between Concurrent Resistance and Endurance Exercise: Molecular Bases and the Role of Individual Training Variables

Open access

Fyfe, Jackson J., Bishop, David J., Stepto, Nigel K.·2014·Sports Medicine

Open this paper in CoChat — free account

Abstract

Concurrent training is defined as simultaneously incorporating both resistance and endurance exercise within a periodized training regime. Despite the potential additive benefits of combining these divergent exercise modes with regards to disease prevention and athletic performance, current evidence suggests that this approach may attenuate gains in muscle mass, strength, and power compared with undertaking resistance training alone. This has been variously described as the interference effect or concurrent training effect. In recent years, understanding of the molecular mechanisms mediating training adaptation in skeletal muscle has emerged and provided potential mechanistic insight into the concurrent training effect. Although it appears that various molecular signaling responses induced in skeletal muscle by endurance exercise can inhibit pathways regulating protein synthesis and stimulate protein breakdown, human studies to date have not observed such molecular 'interference' following acute concurrent exercise that might explain compromised muscle hypertrophy following concurrent training. However, given the multitude of potential concurrent training variables and the limitations of existing evidence, the potential roles of individual training variables in acute and chronic interference are not fully elucidated. The present review explores current evidence for the molecular basis of the specificity of training adaptation and the concurrent interference phenomenon. Additionally, insights provided by molecular and performance-based concurrent training studies regarding the role of individual training variables (i.e., within-session exercise order, between-mode recovery, endurance training volume, intensity, and modality) in the concurrent interference effect are discussed, along with the limitations of our current understanding of this complex paradigm.

Integrity signals

Registry

Crossref · 10.1007/s40279-014-0162-1

Cites

192 of 192 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Aviat space environ med
(1992) · Applied Ergonomics · doi:10.1016/0003-6870(92)90338-v · Cited by 7,153
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
Inoki, K., Zhu, T., & Guan, K.-L. (2003) · Cell · doi:10.1016/s0092-8674(03)00929-2 · Cited by 3,914
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
Gwinn, D. M., Shackelford, D. B., Egan, D. F., Mihaylova, M. M., Mery, A., Vasquez, D. S., Turk, B. E., & Shaw, R. J. (2008) · Molecular Cell · doi:10.1016/j.molcel.2008.03.003 · Cited by 3,849
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Inoki, K., Li, Y., Zhu, T., Wu, J., & Guan, K.-L. (2002) · Nature Cell Biology · doi:10.1038/ncb839 · Cited by 3,083
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L., & Sabatini, D. M. (2008) · Science · doi:10.1126/science.1157535 · Cited by 2,773
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
Bodine, S. C., Stitt, T. N., Gonzalez, M., Kline, W. O., Stover, G. L., Bauerlein, R., Zlotchenko, E., Scrimgeour, A., Lawrence, J. C., Glass, D. J., et al. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1014 · Cited by 2,752
Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes
Kelley, D. E., He, J., Menshikova, E. V., & Ritov, V. B. (2002) · Diabetes · doi:10.2337/diabetes.51.10.2944 · Cited by 2,321
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Jung, C. H., Jun, C. B., Ro, S.-H., Kim, Y.-M., Otto, N. M., Cao, J., Kundu, M., & Kim, D.-H. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-12-1249 · Cited by 2,025
Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
Holloszy, J. O., & Coyle, E. F. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.56.4.831 · Cited by 1,985
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.
Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00211-4 · Cited by 1,964

Show all 192 references

Research works printed but not linked: 4

Hennessy L, Watson A. The interference effects of training for strength and endurance simultaneously. J Strength Cond Res. 1994;12:9–12.
Gravelle BL, Blessing DL. Physiological adaptation in women concurrently training for strength and endurance. J Strength Cond Res. 2000;14:5–13.
Craig B, Lucas J, Pohlman R. Effects of running, weightlifting and a combination of both on growth hormone release. J Appl Sport Sci Res. 1991;5:198–203.
Sporer BC, Wenger HA. Effects of aerobic exercise on strength performance following various periods of recovery. J Strength Cond Res. 2003;17(4):638–44.

Sorted by citations

Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association
Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290
Sarcopenia from mechanism to diagnosis and treatment in liver disease
Dasarathy, S., & Merli, M. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.07.040 · Cited by 608
Concurrent exercise training: do opposites distract?
Coffey, V. G., & Hawley, J. A. (2017) · The Journal of Physiology · doi:10.1113/jp272270 · Cited by 351
Strength training in soccer with a specific focus on highly trained players
Silva, J. R., Nassis, G. P., & Rebelo, A. (2015) · Sports Medicine - Open · doi:10.1186/s40798-015-0006-z · Cited by 269
The Impact of Resistance Training on Swimming Performance: A Systematic Review
Crowley, E., Harrison, A. J., & Lyons, M. (2017) · Sports Medicine · doi:10.1007/s40279-017-0730-2 · Cited by 221
Minimal-dose resistance training for improving muscle mass, strength, and function: A narrative review of current evidence and practical considerations
Fyfe, J. J., Hamilton, D. L., & Daly, R. M. (2022) · Sports Medicine · doi:10.1007/s40279-021-01605-8 · Cited by 172
Self-citation
The Transition Period in Soccer: A Window of Opportunity
Silva, J. R., Brito, J., Akenhead, R., & Nassis, G. P. (2015) · Sports Medicine · doi:10.1007/s40279-015-0419-3 · Cited by 177
Effects of Strength Training on Running Economy in Highly Trained Runners: A Systematic Review With Meta-Analysis of Controlled Trials
Balsalobre‐Fernández, C., Santos‐Concejero, J., & Grivas, G. V. (2015) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001316 · Cited by 167
Skeletal muscle hypertrophy with concurrent exercise training: Contrary evidence for an interference effect
Murach, K. A., & Bagley, J. R. (2016) · Sports Medicine · doi:10.1007/s40279-016-0496-y · Cited by 158
Transference effect of vertical and horizontal plyometrics on sprint performance of high-level U-20 soccer players
Loturco, I., Pereira, L. A., Kobal, R., Zanetti, V., Kitamura, K., Abad, C. C. C., & Nakamura, F. Y. (2015) · Journal of Sports Sciences · doi:10.1080/02640414.2015.1081394 · Cited by 157
How to Construct, Conduct and Analyze an Exercise Training Study?
Hecksteden, A., Faude, O., Meyer, T., & Donath, L. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01007 · Cited by 172
The physiological effects of concurrent strength and endurance training sequence: a systematic review and meta-analysis.
Murlasits, Z., Kneffel, Z., & Thalib, L. (2018) · Journal of Sports Sciences · doi:10.1080/02640414.2017.1364405 · Cited by 150
Compatibility of Concurrent Aerobic and Strength Training for Skeletal Muscle Size and Function: An Updated Systematic Review and Meta-Analysis
Schumann, M., Feuerbacher, J. F., Sünkeler, M., Freitag, N., Rønnestad, B. R., Doma, K., & Lundberg, T. R. (2022) · Sports Medicine · doi:10.1007/s40279-021-01587-7 · Cited by 156
Optimising training adaptations and performance in military environment
Kyröläinen, H., Pihlainen, K., Vaara, J. P., Ojanen, T., & Santtila, M. (2017) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2017.11.019 · Cited by 137
Genetics and sports performance: the present and future in the identification of talent for sports based on DNA testing
Varillas‐Delgado, D., Coso, J. D., Gutiérrez‐Hellín, J., Aguilar‐Navarro, M., Muñoz, A., Maestro, A., & Morencos, E. (2022) · European Journal of Applied Physiology · doi:10.1007/s00421-022-04945-z · Cited by 156
Performance in sports – With specific emphasis on the effect of intensified training
Bangsbo, J. (2015) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12605 · Cited by 163
Resistance Training Recommendations to Maximize Muscle Hypertrophy in an Athletic Population: Position Stand of the IUSCA
Schoenfeld, B. J., Fisher, J. P., Grgić, J., Haun, C. T., Helms, E. R., Phillips, S. M., Steele, J., & Vigotsky, A. D. (2021) · International Journal of Strength and Conditioning · doi:10.47206/ijsc.v1i1.81 · Cited by 141
Neuromuscular Responses to Conditioned Soccer Sessions Assessed via GPS-Embedded Accelerometers: Insights Into Tactical Periodization
Buchheit, M., Lacome, M., Cholley, Y., & Simpson, B. M. (2017) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2017-0045 · Cited by 125
Periodization and Block Periodization in Sports: Emphasis on Strength-Power Training—A Provocative and Challenging Narrative
Stone, M. H., Hornsby, W. G., Haff, G. G., Fry, A. C., Suarez, D. G., Liu, J., González‐Ravé, J. M., & Pierce, K. C. (2021) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000004050 · Cited by 138
Sarcopenia: Ammonia metabolism and hepatic encephalopathy
Jindal, A., & Jagdish, R. K. (2019) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2019.0015 · Cited by 117
Glycogen availability and skeletal muscle adaptations with endurance and resistance exercise
Knuiman, P., Hopman, M. T. E., & Mensink, M. (2015) · Nutrition & Metabolism · doi:10.1186/s12986-015-0055-9 · Cited by 113
A Brief Review on Concurrent Training: From Laboratory to the Field
Methenitis, S. K. (2018) · Sports · doi:10.3390/sports6040127 · Cited by 119
Physical training considerations for optimizing performance in essential military tasks
Vaara, J. P., Groeller, H., Drain, J. R., Kyröläinen, H., Pihlainen, K., Ojanen, T., Connaboy, C., Santtila, M., Agostinelli, P. J., & Nindl, B. C. (2021) · European Journal of Sport Science · doi:10.1080/17461391.2021.1930193 · Cited by 103
The role of intra-session exercise sequence in the interference effect: a systematic review with meta-analysis.
Eddens, L., van Someren, K., & Howatson, G. (2018) · Sports Medicine · doi:10.1007/s40279-017-0784-1 · Cited by 100
Physical Fitness Among Swedish Military Conscripts and Long-Term Risk for Type 2 Diabetes Mellitus
Crump, C., Sundquist, J., Winkleby, M. A., Sieh, W., & Sundquist, K. (2016) · Annals of Internal Medicine · doi:10.7326/m15-2002 · Cited by 102
Effects of morning versus evening combined strength and endurance training on physical performance, muscle hypertrophy, and serum hormone concentrations
Küüsmaa-Schildt, M., Schumann, M., Sedliak, M., Kraemer, W. J., Newton, R. U., Malinen, J.-P., Nyman, K., HÄKKINEN, A. H., & Häkkinen, K. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0271 · Cited by 108
Mechanical, Material and Morphological Adaptations of Healthy Lower Limb Tendons to Mechanical Loading: A Systematic Review and Meta-Analysis
Lazarczuk, S. L., Maniar, N., Opar, D. A., Duhig, S. J., SHIELD, A. J., Barrett, R., & Bourne, M. N. (2022) · Sports Medicine · doi:10.1007/s40279-022-01695-y · Cited by 103
Mixed Training Methods: Effects of Combining Resisted Sprints or Plyometrics with Optimum Power Loads on Sprint and Agility Performance in Professional Soccer Players
Loturco, I., Kobal, R., Kitamura, K., Abad, C. C. C., Faust, B., Almeida, L. G., & Pereira, L. A. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.01034 · Cited by 96
Variables Influencing the Effectiveness of Creatine Supplementation as a Therapeutic Intervention for Sarcopenia
Candow, D. G., Forbes, S. C., Chilibeck, P. D., Cornish, S. M., Antonio, J., & Kreider, R. B. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00124 · Cited by 89
The compatibility of concurrent high intensity interval training and resistance training for muscular strength and hypertrophy: a systematic review and meta-analysis
Sabag, A., Najafi, A., Michael, S., Esgin, T., Halaki, M., & Hackett, D. (2018) · Journal of Sports Sciences · doi:10.1080/02640414.2018.1464636 · Cited by 90
Endurance Training Intensity Does Not Mediate Interference to Maximal Lower-Body Strength Gain during Short-Term Concurrent Training
Fyfe, J. J., Bartlett, J. D., Hanson, E. D., Stepto, N. K., & Bishop, D. J. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00487 · Cited by 96
Self-citation
Does Aerobic Training Promote the Same Skeletal Muscle Hypertrophy as Resistance Training? A Systematic Review and Meta-Analysis
Grgić, J., McIlvenna, L. C., Fyfe, J. J., Sabol, F., Bishop, D. J., Schoenfeld, B. J., & Pedišić, Ž. (2018) · Sports Medicine · doi:10.1007/s40279-018-1008-z · Cited by 96
Self-citation
Concurrent exercise incorporating high-intensity interval or continuous training modulates mTORC1 signaling and microRNA expression in human skeletal muscle
Fyfe, J. J., Bishop, D. J., Zacharewicz, E., Russell, A. P., & Stepto, N. K. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00479.2015 · Cited by 87
Self-citation
Endurance Exercise Enhances the Effect of Strength Training on Muscle Fiber Size and Protein Expression of Akt and mTOR
Kazior, Z., Willis, S. J., Moberg, M., Apró, W., Calbet, J. A. L., Holmberg, H.-C., & Blomstrand, E. (2016) · PLOS ONE · doi:10.1371/journal.pone.0149082 · Cited by 82
The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men
Bagheri, R., Moghadam, B. H., Church, D. D., Tinsley, G. M., Eskandari, M., Moghadam, B. H., Motevalli, M. S., Baker, J. S., Robergs, R. A., & Wong, A. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.110869 · Cited by 81
Concurrent Training and Detraining: brief Review on the Effect of Exercise Intensities
Sousa, A. C., Neiva, H. P., Izquierdo, M., Cadore, E. L., Alves, A. R., & Marinho, D. A. (2019) · International Journal of Sports Medicine · doi:10.1055/a-0975-9471 · Cited by 84
The Multimodal Nature of High-Intensity Functional Training: Potential Applications to Improve Sport Performance
Neto, J. H. F., & Kennedy, M. D. (2019) · Sports · doi:10.3390/sports7020033 · Cited by 90
Training and Competition Readiness in Triathlon
Etxebarria, N., Mujika, I., & Pyne, D. B. (2019) · Sports · doi:10.3390/sports7050101 · Cited by 93
Maximal muscular power: lessons from sprint cycling
Douglas, J. M., Ross, A., & Martin, J. C. (2021) · Sports Medicine - Open · doi:10.1186/s40798-021-00341-7 · Cited by 82
High-intensity interval training (HIT) for effective and time-efficient pre-surgical exercise interventions
Weston, M., Weston, K. L., Prentis, J. M., & Snowden, C. P. (2016) · Perioperative Medicine · doi:10.1186/s13741-015-0026-8 · Cited by 81
Effects of high-intensity functional training on physical fitness and sport-specific performance among the athletes: A systematic review with meta-analysis
Wang, X., Soh, K. G., Samsudin, S., Deng, N., Liu, X., Zhao, Y., & Akbar, S. (2023) · PLoS ONE · doi:10.1371/journal.pone.0295531 · Cited by 107
Enhanced skeletal muscle ribosome biogenesis, yet attenuated mTORC1 and ribosome biogenesis-related signalling, following short-term concurrent versus single-mode resistance training
Fyfe, J. J., Bishop, D. J., Bartlett, J. D., Hanson, E. D., Anderson, M. J., Garnham, A. P., & Stepto, N. K. (2018) · Scientific Reports · doi:10.1038/s41598-017-18887-6 · Cited by 69
Self-citation
Training Considerations for Optimising Endurance Development: An Alternate Concurrent Training Perspective
Doma, K., Deakin, G. B., Schumann, M., & Bentley, D. J. (2019) · Sports Medicine · doi:10.1007/s40279-019-01072-2 · Cited by 68
Effects of light-load maximal lifting velocity weight training vs. combined weight training and plyometrics on sprint, vertical jump and strength performance in adult soccer players
Rodríguez‐Rosell, D., Torres‐Torrelo, J., Franco-Márquez, F., González-Suárez, J. M., & González‐Badillo, J. J. (2017) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2016.11.010 · Cited by 66
Interpreting Adaptation to Concurrent Compared with Single-Mode Exercise Training: Some Methodological Considerations
Fyfe, J. J., & Loenneke, J. P. (2017) · Sports Medicine · doi:10.1007/s40279-017-0812-1 · Cited by 68
Self-citation
Scheduling of training and recovery during the in‐season weekly micro‐cycle: Insights from team sport practitioners
Cross, R. L., Siegler, J. C., Marshall, P. W., & Lovell, R. J. (2019) · European Journal of Sport Science · doi:10.1080/17461391.2019.1595740 · Cited by 63
Skeletal Muscle Ribosome and Mitochondrial Biogenesis in Response to Different Exercise Training Modalities
Mesquita, P. H. C., Vann, C. G., Phillips, S. M., McKendry, J., Young, K. C., Kavazis, A. N., & Roberts, M. D. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.725866 · Cited by 62
The Effects of Concurrent Aerobic and Strength Training on Muscle Fiber Hypertrophy: A Systematic Review and Meta-Analysis
Lundberg, T. R., Feuerbacher, J. F., Sünkeler, M., & Schumann, M. (2022) · Sports Medicine · doi:10.1007/s40279-022-01688-x · Cited by 62
Interference Phenomenon with Concurrent Strength and High-Intensity Interval Training-Based Aerobic Training: An Updated Model
VECHIN, F. C., Conceição, M. S., Telles, G. D., Libardi, C. A., & Ugrinowitsch, C. (2021) · Sports Medicine · doi:10.1007/s40279-020-01421-6 · Cited by 69
Exercise and the control of muscle mass in human
Francaux, M., & Deldicque, L. (2018) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-018-2217-x · Cited by 68
Looking Ahead Perspective: Where Will the Future of Exercise Biology Take Us?
Zierath, J. R., & Wallberg‐Henriksson, H. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.06.015 · Cited by 59
Concurrent Training for Sports Performance: The 2 Sides of the Medal
Berryman, N., Mujika, I., & Bosquet, L. (2018) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2018-0103 · Cited by 58
Effects of strength, explosive and plyometric training on energy cost of running in ultra‐endurance athletes
Giovanelli, N., Taboga, P., Rejc, E., & Lazzer, S. (2017) · European Journal of Sport Science · doi:10.1080/17461391.2017.1305454 · Cited by 58
Nutritional strategies to support concurrent training
Pérez‐Schindler, J., Hamilton, D. L., Moore, D. R., Baar, K., & Philp, A. (2014) · European Journal of Sport Science · doi:10.1080/17461391.2014.950345 · Cited by 63
The effect of concurrent training organisation in youth elite soccer players
Enright, K. J., Morton, J. P., Iga, J., & Drust, B. (2015) · European Journal of Applied Physiology · doi:10.1007/s00421-015-3218-5 · Cited by 57
Effect of Physical Methods of Lymphatic Drainage on Postexercise Recovery of Mixed Martial Arts Athletes
Żebrowska, A., Trybulski, R., Roczniok, R., & Marcol, W. (2017) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0000000000000485 · Cited by 51
The effect of two concurrent exercise modalities on serum concentrations of FGF21, irisin, follistatin, and myostatin in men with type 2 diabetes mellitus
Rad, M. M., Bijeh, N., Hosseini, S. R. A., & Saeb, A. R. (2020) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2020.1829649 · Cited by 51
Self-control training leads to enhanced cardiovascular exercise performance
Bray, S. R., Graham, J. D., & Saville, P. D. (2014) · Journal of Sports Sciences · doi:10.1080/02640414.2014.949830 · Cited by 48
Faster Futsal Players Perceive Higher Training Loads and Present Greater Decreases in Sprinting Speed During the Preseason
Nakamura, F. Y., Pereira, L. A., Rabelo, F. N., Ramírez‐Campillo, R., & Loturco, I. (2015) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001257 · Cited by 48
Effects of regular sauna bathing in conjunction with exercise on cardiovascular function: a multi-arm, randomized controlled trial
Lee, E., Kolunsarka, I., Kostensalo, J., Ahtiainen, J. P., Haapala, E. A., Willeit, P., Kunutsor, S. K., & Laukkanen, J. A. (2022) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00076.2022 · Cited by 49
Order of same-day concurrent training influences some indices of power development, but not strength, lean mass, or aerobic fitness in healthy, moderately-active men after 9 weeks of training
Lee, M. J.-C., Ballantyne, J. K., Chagolla, J., Hopkins, W. G., Fyfe, J. J., Phillips, S. M., Bishop, D. J., & Bartlett, J. D. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233134 · Cited by 50
Self-citation
The Effects of Dietary Protein Supplementation on Acute Changes in Muscle Protein Synthesis and Longer-Term Changes in Muscle Mass, Strength, and Aerobic Capacity in Response to Concurrent Resistance and Endurance Exercise in Healthy Adults: A Systematic Review
Hartono, F. A., Martin-Arrowsmith, P. W., Peeters, W., & Churchward‐Venne, T. A. (2022) · Sports Medicine · doi:10.1007/s40279-021-01620-9 · Cited by 50
Effects of Running-Specific Strength Training, Endurance Training, and Concurrent Training on Recreational Endurance Athletes’ Performance and Selected Anthropometric Parameters
Prieto-González, P., & Sedláček, J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191710773 · Cited by 43
Concurrent Training in Rugby Sevens: Effects of High-Intensity Interval Exercises
Robineau, J., Lacome, M., Piscione, J., Bigard, X. A., & Babault, N. (2016) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2015-0370 · Cited by 43
Supervised Physical Training Enhances Muscle Strength but Not Muscle Mass in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy: A Systematic Review and Meta-Analysis
Chen, Z., Zhang, Y., Lu, C., Zeng, H., Schumann, M., & Cheng, S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00843 · Cited by 44
Possible Effects of Beetroot Supplementation on Physical Performance Through Metabolic, Neuroendocrine, and Antioxidant Mechanisms: A Narrative Review of the Literature
Arazi, H., & Eghbali, E. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.660150 · Cited by 47
Prolonged force depression after mechanically demanding contractions is largely independent of Ca 2+ and reactive oxygen species
Kamandulis, S., Leite, F. D. S., Hernández, A., Katz, A., Brazaitis, M., Bruton, J. D., Venckūnas, T., Masiulis, N., Mickevičienė, D., Eimantas, N., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700019r · Cited by 40
Transference effect of short-term optimum power load training on the punching impact of elite boxers
Loturco, I., Pereira, L. A., Kobal, R., Fernandes, V., Reis, V. P., Romano, F., Alves, M., Freitas, T. T., & McGuigan, M. (2021) · Journal of Strength & Conditioning Research · doi:10.1519/jsc.0000000000003165 · Cited by 40
Aerobic Adaptations to Resistance Training: The Role of Time under Tension
Mang, Z. A., Ducharme, J. B., Mermier, C. M., Kravitz, L. R., Magalhães, F. D. C., & Amorim, F. T. (2022) · International Journal of Sports Medicine · doi:10.1055/a-1664-8701 · Cited by 42
Superimposed Whole-Body Electrostimulation Augments Strength Adaptations and Type II Myofiber Growth in Soccer Players During a Competitive Season
Filipovic, A., DeMarees, M., Grau, M., Hollinger, A., Seeger, B., Schiffer, T., Bloch, W., & Gehlert, S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01187 · Cited by 39
Molecular Regulation of Skeletal Muscle Growth and Organelle Biosynthesis: Practical Recommendations for Exercise Training
Solsona, R., Pavlin, L., Bernardi, H., & Sanchez, A. M. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052741 · Cited by 42
Concurrent Training in Prepubescent Children: The Effects of 8 Weeks of Strength and Aerobic Training on Explosive Strength and Vo 2max
Alves, A. R., Marta, C., Neiva, H. P., Izquierdo, M., & Marques, M. C. (2015) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001294 · Cited by 37
Effects of Dietary Nitrate Supplementation on Weightlifting Exercise Performance in Healthy Adults: A Systematic Review
San Juan, A. F., Dominguez, R., Lago-Rodríguez, Á., Montoya, J. J., Tan, R., & Bailey, S. J. (2020) · Nutrients · doi:10.3390/nu12082227 · Cited by 36
Strength Training for Endurance Athletes
Bazyler, C. D., Abbott, H., Bellon, C. R., Taber, C. B., & Stone, M. H. (2015) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000131 · Cited by 42
The Effects of Concurrent Training Order on Satellite Cell-Related Markers, Body Composition, Muscular and Cardiorespiratory Fitness in Older Men with Sarcopenia
مقدم, ب. ه., Bagheri, R., Ashtary‐Larky, D., Tinsley, G. M., Eskandari, M., Wong, A., مقدم, ب. ه., Kreider, R. B., & Baker, J. S. (2020) · The journal of nutrition health & aging · doi:10.1007/s12603-020-1431-3 · Cited by 35
The effects of saffron ( Crocus sativus L.) in conjunction with concurrent training on body composition, glycaemic status, and inflammatory markers in obese men with type 2 diabetes mellitus: A randomized double‐blind clinical trial
Moghadam, B. H., Rashidlamir, A., Hosseini, S. R. A., Gaeini, A. A., & Kaviani, M. (2022) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.15222 · Cited by 35
Exercise Counteracts the Deleterious Effects of Cancer Cachexia
Tsitkanou, S., Murach, K. A., Washington, T. A., & Greene, N. P. (2022) · Cancers · doi:10.3390/cancers14102512 · Cited by 38
Exercise-based rehabilitation on functionality and quality of life in head and neck cancer survivors. A systematic review and meta-analysis
Pérez, I. M. M., Pérez, S. E. M., García, R. P., Lupgens, D. D. Z., Martínez, G. B., González, C. R., Yáñez, N. K., & Hernández, F. R. (2023) · Scientific Reports · doi:10.1038/s41598-023-35503-y · Cited by 32
Combined effects of very short “all out” efforts during sprint and resistance training on physical and physiological adaptations after 2 weeks of training
Benítez‐Flores, S., Medeiros, A. R., Voltarelli, F. A., Iglesias‐Soler, E., Doma, K., Simões, H. G., Rosa, T. D. S., & Boullosa, D. A. (2019) · European Journal of Applied Physiology · doi:10.1007/s00421-019-04125-6 · Cited by 33
The Effect of High Volume Power Training on Repeated High-Intensity Performance and the Assessment of Repeat Power Ability: A Systematic Review
Natera, A., Cardinale, M., & Keogh, J. (2020) · Sports Medicine · doi:10.1007/s40279-020-01273-0 · Cited by 39
Effects of Moderate-to-Heavy Sled Training Using Different Magnitudes of Velocity Loss in Professional Soccer Players
Grazioli, R., Loturco, I., López, P., Setuain, I., Goulart, J., Veeck, F., Inácio, M., Izquierdo, M., Pinto, R. S., & Cadore, E. L. (2020) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003813 · Cited by 32
Does Exercise Training Improve Cardiac-Parasympathetic Nervous System Activity in Sedentary People? A Systematic Review with Meta-Analysis
Casanova‐Lizón, A., Manresa‐Rocamora, A., Flatt, A. A., Sarabia, J. M., & Moya‐Ramón, M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192113899 · Cited by 37
Perceived training load and jumping responses following nine weeks of a competitive period in young female basketball players
Cruz, I. D. F., Pereira, L. A., Kobal, R., Kitamura, K., Cedra, C., Loturco, I., & Abad, C. C. C. (2018) · PeerJ · doi:10.7717/peerj.5225 · Cited by 31
Exercise shapes redox signaling in cancer
Assi, M., Dufresne, S., & Rébillard, A. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101439 · Cited by 34
The Effects of Concurrent Training Versus Aerobic or Resistance Training Alone on Body Composition in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis
Khalafi, M., Kheradmand, S., Maleki, A. H., Symonds, M. E., Rosenkranz, S. K., & Batrakoulis, A. (2025) · Healthcare · doi:10.3390/healthcare13070776 · Cited by 38
Effectiveness of a 16-Week High-Intensity Cardioresistance Training Program in Adults
Greenlee, T. A., Greene, D. R., Ward, N., Reeser, G. E., Allen, C. M., Baumgartner, N. W., Cohen, N. J., Kramer, A. F., Hillman, C. H., & Barbey, A. K. (2017) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001976 · Cited by 35
Exercise and physical activity in cirrhosis: opportunities or perils
Bellar, A., Welch, N., & Dasarathy, S. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00798.2019 · Cited by 33
Physical loading in professional soccer players: Implications for contemporary guidelines to encompass carbohydrate periodization
Anderson, L. J., Drust, B., Close, G. L., & Morton, J. P. (2022) · Journal of Sports Sciences · doi:10.1080/02640414.2022.2044135 · Cited by 34
Physical employment standards, physical training and musculoskeletal injury in physically demanding occupations
Drain, J. R., & Reilly, T. J. (2019) · Work · doi:10.3233/wor-192963 · Cited by 28
Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes
Thomassen, M., Gunnarsson, T. P., Christensen, P. M., Pavlović, D., Shattock, M. J., & Bangsbo, J. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00081.2015 · Cited by 29
Skeletal muscle LINE-1 ORF1 mRNA is higher in older humans but decreases with endurance exercise and is negatively associated with higher physical activity
Roberson, P. A., Romero, M. A., Osburn, S. C., Mumford, P. W., Vann, C. G., Fox, C. D., McCullough, D. J., Brown, M. D., & Roberts, M. D. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00352.2019 · Cited by 28
The efficacy of protein supplementation during recovery from muscle-damaging concurrent exercise
Eddens, L., Browne, S., Stevenson, E., Sanderson, B., van Someren, K. A., & Howatson, G. (2017) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2016-0626 · Cited by 28
Hormonal response patterns are differentially influenced by physical conditioning programs during basic military training
Drain, J. R., Groeller, H., Burley, S. D., & Nindl, B. C. (2017) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2017.08.020 · Cited by 26
High-Intensity Interval Training: A Potential Exercise Countermeasure During Human Spaceflight
Hurst, C., Scott, J. P. R., Weston, K. L., & Weston, M. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00581 · Cited by 29
Etiology and Recovery of Neuromuscular Function Following Academy Soccer Training
Deely, C., Tallent, J., Bennett, R., Woodhead, A., Goodall, S., Thomas, K., & Howatson, G. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.911009 · Cited by 29
Effects of concurrent training sequence on VO2max and lower limb strength performance: A systematic review and meta-analysis
Gao, J., & Yu, L. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1072679 · Cited by 26
Acute Effects of Aerobic Exercise on Muscle Strength and Power in Trained Male Individuals: A Systematic Review with Meta-analysis
Markov, A., Chaabène, H., Hauser, L., Behm, S., Bloch, W., Puta, C., & Granacher, U. (2021) · Sports Medicine · doi:10.1007/s40279-021-01615-6 · Cited by 32
Effects of 16 weeks of two different high-protein diets with either resistance or concurrent training on body composition, muscular strength and performance, and markers of liver and kidney function in resistance-trained males
Bagheri, R., Kargarfard, M., Sadeghi, R., Scott, D. S., & CAMERA, D. M. (2023) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2023.2236053 · Cited by 35
Enhancing of Women Functional Status with Metabolic Syndrome by Cardioprotective and Anti-Inflammatory Effects of Combined Aerobic and Resistance Training
Tibana, R. A., Nascimento, D. D. C., de Sousa, N. M. F., Souza, V. C., Durigan, J. L. Q., Vieira, A., Bottaro, M., Nóbrega, O. D. T., de Almeida, J. A., Navalta, J. W., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110160 · Cited by 30
Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics
Minnock, D., Annibalini, G., le Roux, C. W., Contarelli, S., Krause, M. D. S., Saltarelli, R., Valli, G., Stocchi, V., Barbieri, E., & VITO, G. D. (2020) · European Journal of Applied Physiology · doi:10.1007/s00421-020-04491-6 · Cited by 23

Authors: Fyfe, J. J., Bishop, D. J., & Stepto, N. K.
Affiliations: Victoria University (AU)
Corresponding author: Fyfe, Jackson J.
ORCID: Fyfe, Jackson J.
Bishop, David J.
Stepto, Nigel K.
Venue: Sports Medicine
Publisher: Springer Science and Business Media LLC
Published: 2014-04-12
Volume: 44
Issue: 6
Pages: 743-762
ISSN: 0112-1642 (ISSN-L)
1179-2035
DOI: 10.1007/s40279-014-0162-1
OpenAlex: W2076115872
Cited by: 347
References: 192
Citations by year: 2026: 42 · 2025: 28 · 2024: 22 · 2023: 36 · 2022: 31 · 2021: 34 · 2020: 27 · 2019: 27 · 2018: 38 · 2017: 24 · 2016: 18 · 2015: 16 · 2014: 4
FWCI: 2.07
Type: journal article
Language: en
Open access: green
figshare.com
Licence: cc-by
www.springer.com/tdm (tdm)
Locations: Sports Medicine (publishedVersion)
PubMed (publishedVersion)
Victoria University Research Repository (Victoria University) (submittedVersion)
Figshare (submittedVersion, cc-by)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: concurrent training, interference effects, resistance training, endurance exercise, muscle hypertrophy, skeletal muscle protein synthesis, protein degradation, training specificity, exercise order, exercise intensity, exercise modalities, muscle strength and power
MeSH terms: Adaptation, Physiological, Energy Metabolism, Humans, Hypertrophy, Muscle Proteins, Physical Education and Training, Physical Endurance, Muscle, Skeletal, Muscle Fibers, Skeletal, Muscle Strength, Resistance Training

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Interference between Concurrent Resistance and Endurance Exercise: Molecular Bases and the Role of Individual Training Variables

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks