Vascular endothelium: an integrator of pathophysiologic stimuli in atherosclerosis.

The pathogenesis of atherosclerosis: a perspective for the 1990s

Ross, R. (1993) · Nature · doi:10.1038/362801a0 · Cited by 10,618 · see citing works

Adhesion receptors of the immune system

Springer, T. A. (1990) · Nature · doi:10.1038/346425a0 · Cited by 6,477 · see citing works

Role of oxidized low density lipoprotein in atherogenesis.

Witztum, J. L., & Steinberg, D. H. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115499 · Cited by 2,682 · see citing works

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

Elices, M. J., Osborn, L., Takada, Y., Crouse, C., Luhowskyj, S., Hemler, M. E., & Lobb, R. R. (1990) · Cell · doi:10.1016/0092-8674(90)90661-w · Cited by 1,808 · see citing works

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

Cybulsky, M. I., & Gimbrone, M. A. (1991) · Science · doi:10.1126/science.1990440 · Cited by 1,710 · see citing works

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

Osborn, L., Hession, C. A., Tizard, R., Vassallo, C., Luhowskyj, S., Rosso, G. C., & Lobb, R. R. (1989) · Cell · doi:10.1016/0092-8674(89)90775-7 · Cited by 1,690 · see citing works

Cytokines and endothelial cell biology

Pober, J. S., & Cotran, R. S. (1990) · Physiological Reviews · doi:10.1152/physrev.1990.70.2.427 · Cited by 1,251 · see citing works

Studies of hypercholesterolemia in the nonhuman primate. I. Changes that lead to fatty streak formation.

Faggiotto, A., Ross, R., & Harker, L. A. (1984) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.4.4.323 · Cited by 990 · see citing works

Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.

Berliner, J. A., Territo, M., Sevanian, A., Ramin, S., Kim, J. A., Bamshad, B., Esterson, M., & Fogelman, A. M. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114562 · Cited by 924 · see citing works

Monocyte chemoattractant protein-1 in human atheromatous plaques.

Nelken, N. A., Coughlin, S. R., Gordon, D., & Wilcox, J. N. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115411 · Cited by 878 · see citing works

Selectins.

Bevilacqua, M. P., & Nelson, R. M. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116210 · Cited by 876 · see citing works

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

Kume, N., Cybulsky, M. I., & Gimbrone, M. A. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115932 · Cited by 824 · see citing works

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis.

O’Brien, K. D., Allen, M. D., McDonald, T. O., Chait, A., Harlan, J. M., Fishbein, D., McCarty, J. M., Ferguson, M. S., Hudkins, K. L., & Benjamin, C. D. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116670 · Cited by 701 · see citing works

The Pathogenesis of Atherosclerosis: Atherogenesis and Inflammation

Munro, J. M., & Cotran, R. S. (1989) · Humana Press eBooks · doi:10.1007/978-1-4612-4502-5_10 · Cited by 698 · see citing works

An atherogenic diet rapidly induces VCAM-1, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium.

Li, H., Cybulsky, M. I., Gimbrone, M. A., & Libby, P. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.2.197 · Cited by 686 · see citing works

Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions.

Libby, P., & Hansson, G. K. (1991) · PubMed · Cited by 669 · see citing works

Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.

Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse, C. P., Klunk, D. A., & Schleimer, R. P. (1991) · The Journal of Experimental Medicine · doi:10.1084/jem.173.6.1553 · Cited by 650 · see citing works

Expression of intercellular adhesion molecule-1 in atherosclerotic plaques.

Poston, R. N., Haskard, D. O., Coucher, J., Gall, N. P., & Johnson-Tidey, R. R. (1992) · PubMed Central · Cited by 583 · see citing works

Studies on the pathogenesis of atherosclerosis. I. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats.

Joris, I., Zand, T., Nunnari, J. J., Krolikowski, F. J., & Majno, G. (1983) · PubMed Central · Cited by 478 · see citing works

Inducible cell adhesion molecule 110 (INCAM-110) is an endothelial receptor for lymphocytes. A CD11/CD18-independent adhesion mechanism.

Rice, G. E., Munro, J. M., & Bevilacqua, M. P. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.171.4.1369 · Cited by 399 · see citing works

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion

Spertini, O., Luscinskas, F. W., Kansas, G. S., Munro, J. M., Griffin, J. D., Gimbrone, M. A., & Tedder, T. F. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.147.8.2565 · Cited by 394 · see citing works

Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis.

Clinton, S. K., Underwood, R., Hayes, L., Sherman, M. L., Kufe, D. W., & Libby, P. (1992) · PubMed Central · Cited by 378 · see citing works

Initiation of atherosclerotic lesions in cholesterol-fed rabbits. II. Selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries.

Schwenke, D. C., & Carew, T. E. (1989) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.9.6.908 · Cited by 344 · see citing works

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene.

Cybulsky, M. I., Fries, J. W. U., Williams, A. J., Sultan, P. K., Eddy, R. L., Byers, M. G., Shows, T. B., Gimbrone, M. A., & Collins, T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.17.7859 · Cited by 178 · see citing works

Vascular Endothelium in Hemostasis and Thrombosis

Gimbrone, M. A. (1987) · Cited by 167 · see citing works

Endothelial Cell Biology in Health and Disease

Simionescu, N., & Simionescu, M. (1988) · Springer eBooks · doi:10.1007/978-1-4613-0937-6 · Cited by 118 · see citing works

Endothelial Cell Dysfunctions

(1992) · Springer eBooks · doi:10.1007/978-1-4899-0721-9 · Cited by 83 · see citing works

Endothelial Dysfunction and the Pathogenesis of Atherosclerosis

Gimbrone, M. A. (1980) · Springer eBooks · doi:10.1007/978-1-4612-6071-4_84 · Cited by 60 · see citing works

Endothelial-Leukocyte Adhesion Molecules in Acute Inflammation and Atherogenesis

Cybulsky, M. I., & Gimbrone, M. A. (1992) · Springer eBooks · doi:10.1007/978-1-4899-0721-9_7 · Cited by 23 · see citing works

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Cai, H., & Harrison, D. G. (2000) · Circulation Research · doi:10.1161/01.res.87.10.840 · Cited by 3,839 · see citing works

Hemodynamic shear stress and its role in atherosclerosis

Malek, A. M. (1999) · JAMA · doi:10.1001/jama.282.21.2035 · Cited by 3,650 · see citing works

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

Chiu, J.-J., & Chien, S. (2011) · Physiological Reviews · doi:10.1152/physrev.00047.2009 · Cited by 2,280 · see citing works

The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy

Iorga, A., Cunningham, C. M., Moazeni, S., Ruffenach, G., Umar, S., & Eghbali, M. (2017) · Biology of Sex Differences · doi:10.1186/s13293-017-0152-8 · Cited by 914 · see citing works

Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline

Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887 · see citing works

NADPH Oxidases in Cardiovascular Health and Disease

Cave, A. C., Brewer, A. C., Narayanapanicker, A., Ray, R., Grieve, D. J., Walker, S., & Shah, A. M. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.691 · Cited by 630 · see citing works

Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

Stroes, E. S. G., Kastelein, J. J. P., Cosentino, F., Erkelens, W. D., Wever, R. M. F., Koomans, H. A., Lüscher, T. F., & Rabelink, T. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119131 · Cited by 588 · see citing works

Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury

Khachigian, L. M., Lindner, V., Williams, A. J., & Collins, T. (1996) · Science · doi:10.1126/science.271.5254.1427 · Cited by 517 · see citing works

Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease

Takase, B., Uehata, A., Akima, T., Nagai, T., Nishioka, T., Hamabe, A., Satomura, K., Ohsuzu, F., & Kurita, A. (1998) · The American Journal of Cardiology · doi:10.1016/s0002-9149(98)00702-4 · Cited by 453 · see citing works

Glutathione: Antioxidant Properties Dedicated to Nanotechnologies

Gaucher, C., Boudier, A., Bonetti, J., Clarot, I., Leroy, P., & Parent, M. (2018) · Antioxidants · doi:10.3390/antiox7050062 · Cited by 332 · see citing works

Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase

Stroes, E. S. G., van Faassen, E. E., Yo, M., Martasek, P., Boer, P., Govers, R., & Rabelink, T. J. (2000) · Circulation Research · doi:10.1161/01.res.86.11.1129 · Cited by 285 · see citing works

Vascular mechanotransduction

Davis, M. J., Earley, S., Li, Y.-S., & Chien, S. (2023) · Physiological Reviews · doi:10.1152/physrev.00053.2021 · Cited by 273 · see citing works

Resistin is secreted from macrophages in atheromas and promotes atherosclerosis

JUNG, H., Park, K. S., CHO, Y., CHUNG, S., Cho, S., CHO, S., Kim, S. J., KIM, S., LEE, H., & Park, K. S. (2005) · Cardiovascular Research · doi:10.1016/j.cardiores.2005.09.015 · Cited by 260 · see citing works

Testing Endothelial Vasomotor Function

Ganz, P., & Vita, J. A. (2003) · Circulation · doi:10.1161/01.cir.0000089507.19675.f9 · Cited by 249 · see citing works

Atherosclerosis and Cancer

Ross, J. S., Stagliano, N. E., Donovan, M. J., Breitbart, R. E., & Ginsburg, G. S. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb03949.x · Cited by 228 · see citing works

Chronic Inflammatory Diseases and Endothelial Dysfunction

Castellon, X., & Bogdanova, V. (2016) · Aging and disease · doi:10.14336/ad.2015.0803 · Cited by 191 · see citing works

Endothelial Function and Oxidative Stress

Ogita, H., & Liao, J. K. (2004) · Endothelium · doi:10.1080/10623320490482664 · Cited by 188 · see citing works

Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression

Ding, Y., Vaziri, N. D., Coulson, R., Kamanna, V. S., & Roh, D. D. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.1.e11 · Cited by 181 · see citing works

Increased Expression of Lectinlike Oxidized Low Density Lipoprotein Receptor-1 in Initial Atherosclerotic Lesions of Watanabe Heritable Hyperlipidemic Rabbits

Chen, M., Kakutani, M., Minami, M., Kataoka, H., Kume, N., Narumiya, S., Kita, T., Masaki, Τ., & Sawamura, T. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.4.1107 · Cited by 182 · see citing works

Estrogens and Glucocorticoids Inhibit Endothelial Vascular Cell Adhesion Molecule-1 Expression by Different Transcriptional Mechanisms

Simoncini, T., Maffei, S., Basta, G., Barsacchi, G., Genazzani, A. R., Liao, J. K., & Caterina, R. D. (2000) · Circulation Research · doi:10.1161/01.res.87.1.19 · Cited by 182 · see citing works

How Do We Explain the Clinical Benefits of Estrogen?

Gerhard, M. D., & Ganz, P. (1995) · Circulation · doi:10.1161/01.cir.92.1.5 · Cited by 182 · see citing works

Vascular endothelial dysfunction

DEMEYER, G., & HERMAN, A. (1997) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(97)80031-x · Cited by 180 · see citing works

Rapid Effect of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition on Coronary Endothelial Function

Wassmann, S., Faul, A., Hennen, B., Scheller, B., Böhm, M., & Nickenig, G. (2003) · Circulation Research · doi:10.1161/01.res.0000099503.13312.7b · Cited by 177 · see citing works

Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB

Badrichani, A. Z., Stroka, D., Bilbao, G., Curiel, D. T., Bach, F. H., & Ferran, C. J. (1999) · Journal of Clinical Investigation · doi:10.1172/jci2517 · Cited by 174 · see citing works

Vascular actions of insulin with implications for endothelial dysfunction

Potenza, M. A., Addabbo, F., & Montagnani, M. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00297.2009 · Cited by 159 · see citing works

Endothelial Cell Injury in Cardiovascular Surgery: The Intimal Hyperplastic Response

Allaire, É., & Clowes, A. W. (1997) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(96)01045-4 · Cited by 160 · see citing works

Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo

Rooyakkers, T. M., Stroes, E. S. G., Kooistra, M. P., Van Faassen, E. E., Hider, R. C., Rabelink, T. J., & Marx, J. J. M. (2002) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2002.0320s1009.x · Cited by 157 · see citing works

Endothelial nitric oxide synthase transgenic models of endothelial dysfunction

Atochin, D. N., & Huang, P. L. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-010-0867-4 · Cited by 145 · see citing works

Oxidative Stress in Ischemic Heart Disease

Kibel, A., Lukinac, A. M., Đambić, V., Jurić, I., & Selthofer-Relatić, K. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/6627144 · Cited by 149 · see citing works

Asymmetric Dimethylarginine Increases Mononuclear Cell Adhesiveness in Hypercholesterolemic Humans

Chan, J. R., Böger, R. H., Bode‐Böger, S. M., Tangphao, O., Tsao, P. S., Blaschke, T. F., & Cooke, J. P. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.4.1040 · Cited by 140 · see citing works

Abdominal aortic hemodynamics in young healthy adults at rest and during lower limb exercise: quantification using image-based computer modeling

Tang, B. T., Cheng, C. P., Draney, M. T., Wilson, N. M., Tsao, P. S., Herfkens, R. J., & Taylor, C. A. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01301.2005 · Cited by 139 · see citing works

Platelet-Derived Growth Factor Ligand and Receptor Expression in Response to Altered Blood Flow In Vivo

Mondy, J. S., Lindner, V., Miyashiro, J. K., Berk, B. C., Dean, R. H., & Geary, R. L. (1997) · Circulation Research · doi:10.1161/01.res.81.3.320 · Cited by 127 · see citing works

Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reductase

MILLER, S., Walker, S. W., Arthur, J. R., Nicol, F., Pickard, K. M., Lewin, M., Howie, A. F., & Beckett, G. J. (2001) · Clinical Science · doi:10.1042/cs1000543 · Cited by 126 · see citing works

Morning attenuation of endothelium‐dependent, flow‐mediated dilation in healthy young men: Possible connection to morning peak of cardiac events?

Etsuda, H., Takase, B., Kusano, H., Hamabe, A., Kuhara, R., Akima, T., Matsushima, Y., Arakawa, K., Satomura, K., Ohsuzu, F., et al. (1999) · Clinical Cardiology · doi:10.1002/clc.4960220610 · Cited by 124 · see citing works

Multiple anti-inflammatory and anti-atherosclerotic properties of red wine polyphenolic extracts: differential role of hydroxycinnamic acids, flavonols and stilbenes on endothelial inflammatory gene expression

Calabriso, N., Scoditti, E., Massaro, M., Pellegrino, M., Storelli, C., Ingrosso, I., Giovinazzo, G., & Carluccio, M. A. (2015) · European Journal of Nutrition · doi:10.1007/s00394-015-0865-6 · Cited by 118 · see citing works

The role of ENaC in vascular endothelium

Kusche‐Vihrog, K., Jeggle, P., & Oberleithner, H. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1356-3 · Cited by 114 · see citing works

Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction

Yeo, N. J. Y., Chan, E. J. J., & Cheung, C. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01363 · Cited by 117 · see citing works

The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial

Atkin, M., Laight, D. W., & Cummings, M. H. (2016) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2016.01.003 · Cited by 112 · see citing works

Effects of Olive Oil Phenolic Compounds on Inflammation in the Prevention and Treatment of Coronary Artery Disease

de Souza, P. A. L., Marcadenti, A., & Portal, V. L. (2017) · Nutrients · doi:10.3390/nu9101087 · Cited by 109 · see citing works

Endothelium and acute coronary syndromes

Liao, J. K. (1998) · Clinical Chemistry · doi:10.1093/clinchem/44.8.1799 · Cited by 102 · see citing works

Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo

Lee, W., Ku, S., & Bae, J. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.06.013 · Cited by 99 · see citing works

Fluid Shear Stress Induction of the Tissue Factor Promoter In Vitro and In Vivo Is Mediated by Egr-1

Houston, P., Dickson, M. C., Ludbrook, V. J., White, B. P., Schwachtgen, J.-L., McVey, J. H., Mackman, N., Reese, J. M., Gorman, D. G., Campbell, C. J., et al. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.2.281 · Cited by 89 · see citing works

Apigenin protects endothelium-dependent relaxation of rat aorta against oxidative stress

Jin, B., Qian, L.-B., Chen, S., Li, J., Wang, H., Bruce, I. C., Lin, J., & Xia, Q. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.06.020 · Cited by 87 · see citing works

Expression of NF-kappa B and I kappa B-alpha by aortic endothelium in an arterial injury model.

Lindner, V., & Collins, T. (1996) · Europe PMC (PubMed Central) · Cited by 85 · see citing works

Atherosclerosis

Ross, J. S., Stagliano, N. E., Donovan, M. J., Breitbart, R. E., & Ginsburg, G. S. (2001) · Pathology Patterns Reviews · doi:10.1309/ynck-9r19-5ja3-k2k9 · Cited by 83 · see citing works

Biphasic Regulation of Transcription Factor Nuclear Factor-κB Activity in Human Endothelial Cells by Lysophosphatidylcholine Through Protein Kinase C–Mediated Pathway

Sugiyama, S., Kugiyama, K., Ogata, N., Doi, H., Ota, Y., Ohgushi, M., Matsumura, T., Oka, H., & Yasue, H. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.4.568 · Cited by 83 · see citing works

Estrogen, inflammation and cardiovascular risk in women: a critical appraisal

Störk, S., van der Schouw, Y. T., Grobbee, D. E., & Bots, M. L. (2004) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2004.01.005 · Cited by 81 · see citing works

Antioxidants and endothelium protection

Praticò, D. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.03.005 · Cited by 78 · see citing works

A20, a modulator of smooth muscle cell proliferation and apoptosis, prevents and induces regression of neointimal hyperplasia

Patel, V. I., Daniel, S., Longo, C. R., Shrikhande, G., Scali, S. T., Czismadia, E., Groft, C. M., Shukri, T., Mottley, C., Ramsey, H. E., et al. (2006) · The FASEB Journal · doi:10.1096/fj.05-4981com · Cited by 77 · see citing works

Endothelial cell delivery for cardiovascular therapy

Parikh, S. A., & Edelman, E. R. (2000) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00058-2 · Cited by 76 · see citing works

The effect of 17β-estradiol on MCP-1 serum levels in postmenopausal women

Störk, S. (2002) · Cardiovascular Research · doi:10.1016/s0008-6363(01)00461-8 · Cited by 75 · see citing works

Investigative Models in Erectile Dysfunction: A State-of-the-Art Review of Current Animal Models

Chung, E., Young, L. D., & Brock, G. B. (2011) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2011.02505.x · Cited by 73 · see citing works

Albumin Microbubble Adherence to Human Coronary Endothelium: Implications for Assessment of Endothelial Function Using Myocardial Contrast Echocardiography

Villanueva, F. S., Jankowski, R. J., Manaugh, C. A., & Wagner, W. R. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00197-6 · Cited by 70 · see citing works

Apoptosis of endothelial cells is associated with paracrine induction of adhesion molecules: evidence for an interleukin-1beta-dependent paracrine loop.

Hébert, M., Gullans, S. R., Mackenzie, H. S., & Brady, H. R. (1998) · Europe PMC (PubMed Central) · Cited by 69 · see citing works

Functional implications of vascular endothelium in regulation of endothelial nitric oxide synthesis to control blood pressure and cardiac functions

Kumar, G., Dey, S. K., & Kundu, S. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118377 · Cited by 68 · see citing works

Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers

Lowe, F., Gregg, E. O., & McEwan, M. (2009) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2009.069 · Cited by 65 · see citing works

Interrelationship of Free Oxygen Radicals and Endothelial Dysfunction--Modulation by Statins

Waßmann, S., & Nickenig, G. (2003) · Endothelium · doi:10.1080/10623320303357 · Cited by 64 · see citing works

Urokinase Activates the Jak/Stat Signal Transduction Pathway in Human Vascular Endothelial Cells

Dumler, I., Kopmann, A., Weis, A., Mayboroda, O. A., Wagner, K., Gulba, D. C., & Haller, H. G. (1999) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.19.2.290 · Cited by 64 · see citing works

Homocysteine at pathophysiologic concentrations activates human monocyte and induces cytokine expression and inhibits macrophage migration inhibitory factor expression

Su, S.-J., Huang, L., Pai, L.-S., Liu, H., & Chang, K. (2005) · Nutrition · doi:10.1016/j.nut.2005.01.011 · Cited by 63 · see citing works

A Mouse Model of Hypercholesterolemia-Induced Erectile Dysfunction

Xie, D., Odronic, S. I., Wu, F., Pippen, A. M., Donatucci, C. F., & Annex, B. H. (2007) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00518.x · Cited by 63 · see citing works

Selenium supplementation acting through the induction of thioredoxin reductase and glutathione peroxidase protects the human endothelial cell line EAhy926 from damage by lipid hydroperoxides

Lewin, M., Arthur, J. R., Riemersma, R. A., Nicol, F., Walker, S. W., Millar, E. M., Howie, A. F., & Beckett, G. J. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(02)00333-6 · Cited by 63 · see citing works

Selective inhibition by probucol of vascular cell adhesion molecule-1 (VCAM-1) expression in human vascular endothelial cells

Zapolska‐Downar, D., Zapolski-Downar, A., Markiewski, M. M., Ciechanowicz, A., Kaczmarczyk, M., & Naruszewicz, M. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(00)00553-0 · Cited by 63 · see citing works

Betulinic acid ameliorates endothelium-dependent relaxation in l-NAME-induced hypertensive rats by reducing oxidative stress

Fu, J.-Y., Qian, L.-B., Zhu, L.-G., Liang, H.-T., Tan, Y., Lu, H., Lü, J., Wang, H., & Xia, Q. (2011) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2011.08.025 · Cited by 60 · see citing works

Decreased Reendothelialization and Increased Neointima Formation With Endostatin Overexpression in a Mouse Model of Arterial Injury

Hutter, R., Sauter, B. V., Reis, E. D., Roqué, M., Vorchheimer, D. A., Carrick, F. E., Fallon, J. T., Fuster, V., & Badimón, J. J. (2003) · Circulation · doi:10.1161/01.cir.0000058169.21850.ce · Cited by 58 · see citing works

Nitric oxide and hypercholesterolemia: a matter of oxidation and reduction?

Wever, R. M. F., Stroes, E. S. G., & Rabelink, T. J. (1998) · Atherosclerosis · doi:10.1016/s0021-9150(97)00304-3 · Cited by 58 · see citing works

Roles, Actions, and Therapeutic Potential of Specialized Pro-resolving Lipid Mediators for the Treatment of Inflammation in Cystic Fibrosis

Recchiuti, A., Mattoscio, D., & Isopi, E. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00252 · Cited by 57 · see citing works

Overexpression of A1, an NF-κB–Inducible Anti-Apoptotic Bcl Gene, Inhibits Endothelial Cell Activation

Stroka, D., Badrichani, A. Z., Bach, F. H., & Ferran, C. J. (1999) · Blood · doi:10.1182/blood.v93.11.3803 · Cited by 56 · see citing works

Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic AMP via Epac1-dependent induction of suppressor of cytokine signalling-3

Woolson, H. D., Thomson, V. S., Rutherford, C. L., Yarwood, S. J., & Palmer, T. M. (2009) · Cellular Signalling · doi:10.1016/j.cellsig.2009.07.009 · Cited by 52 · see citing works

Macrovascular angiopathy in children and adolescents with type 1 diabetes

Giannini, C., Mohn, A., Chiarelli, F., & Kelnar, C. J. H. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1195 · Cited by 52 · see citing works

Mechanistic Insights of Soluble Uric Acid-related Kidney Disease

Jing, P., Shi, M., Ma, L., & Fu, P. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867326666181211094421 · Cited by 51 · see citing works

Combination of systemic thioacetamide (TAA) injections and ethanol feeding accelerates hepatic fibrosis in C3H/He mice and is associated with intrahepatic up regulation of MMP-2, VEGF and ICAM-1

Kornek, M., Raskopf, E., Gütgemann, I., Ocker, M., Gerceker, S., Gonzalez-Carmona, M. A., Rabe, C., Sauerbruch, T., & Schmitz, V. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2006.03.017 · Cited by 48 · see citing works

Gender differences in age-related endothelial function in the murine aorta

Takenouchi, Y., Kobayashi, T., Matsumoto, T., & Kamata, K. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.03.005 · Cited by 47 · see citing works

C-Reactive Protein and Cardiovascular Diseases

Prasad, K. (2003) · International Journal of Angiology · doi:10.1007/s00547-003-1018-y · Cited by 47 · see citing works

Is There a Relationship Between Chronic Periodontitis and Erectile Dysfunction?

Oğuz, F., Eltas, A., Beytur, A., Akdemir, E., Uslu, M. Ö., & Gunes, A. E. (2012) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2012.02974.x · Cited by 44 · see citing works

Soluble Receptors for Advanced Glycation End Products (sRAGE) as a Predictor of Restenosis Following Percutaneous Coronary Intervention

McNair, E. D., Wells, C. R., Qureshi, A. M., Basran, R., Pearce, C., Orvold, J., Devilliers, J., & Prasad, K. (2010) · Clinical Cardiology · doi:10.1002/clc.20815 · Cited by 44 · see citing works

Microbubbles Stabilized by Protein Shell: From Pioneering Ultrasound Contrast Agents to Advanced Theranostic Systems

Rudakovskaya, P. G., Barmin, R. A., Kuzmin, P. S., Fedotkina, E. P., Sencha, A. N., & Gorin, D. A. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14061236 · Cited by 43 · see citing works

The effects of Ramadan fasting on endothelial function in patients with cardiovascular diseases

Yousefi, B., Faghfoori, Z., Samadi, N., Karami, H., Ahmadi, Y., Badalzadeh, R., Shafiei‐Irannejad, V., Majidinia, M., Ghavimi, H., & Jabbarpour, M. (2014) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2014.61 · Cited by 42 · see citing works

Direct vascular effects of estrogens and selective estrogen receptor modulators

Simoncini, T., & Genazzani, A. R. (2000) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200006000-00004 · Cited by 41 · see citing works

Inflammation in high blood pressure: a clinician perspective

Ghanem, F. A., & Movahed, A. (2007) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2007.01.004 · Cited by 40 · see citing works

Flow-mediated dilatation test using optoacoustic imaging: a proof-of-concept

Karlas, A., Reber, J., Diot, G., Bozhko, D., Anastasopoulou, M., Ibrahim, T., Schwaiger, M., Hyafil, F., & Ntziachristos, V. (2017) · Biomedical Optics Express · doi:10.1364/boe.8.003395 · Cited by 38 · see citing works

Influence of adhesion molecule expression by human brain microvessel endothelium on cancer cell adhesion

Brayton, J., Qing, Z., HART, M. N., VanGilder, J. C., & Fábry, Z. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00127-1 · Cited by 38 · see citing works

Effects of phytoestrogens derived from red clover on atherogenic adhesion molecules in human endothelial cells

Simoncini, T., Garibaldi, S., Fu, X., Pisaneschi, S., Begliuomini, S., Baldacci, C., Lenzi, E., Goglia, L., Giretti, M. S., & Genazzani, A. R. (2008) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318156f9d6 · Cited by 37 · see citing works

Tibolone inhibits leukocyte adhesion molecule expression in human endothelial cells

Simoncini, T., & Genazzani, A. R. (2000) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00206-9 · Cited by 38 · see citing works

Tai Chi Training for Patients with Coronary Heart Disease

Lan, C., Chen, S., Wong, M.-K., & Lai, J. (2008) · KARGER eBooks · doi:10.1159/000134299 · Cited by 36 · see citing works

Moléculas de adhesión endoteliales ICAM-1, VCAM-1 y E-selectina en pacientes con síndrome coronario agudo

Macías, C., Villaescusa, R., del Valle, L., Boffil, V. I. C., Cordero, G., Hernández, A., Hernández, P., & Ballester, J. M. (2003) · Revista Española de Cardiología · doi:10.1016/s0300-8932(03)76837-7 · Cited by 36 · see citing works

Comparative predictive and diagnostic value of flow-mediated vasodilation in the brachial artery and intima media thickness of the carotid artery for assessment of coronary artery disease severity

Matsushima, Y., Takase, B., Uehata, A., Kawano, H., Yano, K., Ohsuzu, F., Ishihara, M., & Kurita, A. (2007) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.04.063 · Cited by 36 · see citing works

Overexpression of cytosolic glutathione peroxidase (GPX1) delays endothelial cell growth and increases resistance to toxic challenges

Faucher, K., Rabinovitch-Chable, H., Barrière, G., Cook‐Moreau, J., & Rigaud, M. (2003) · Biochimie · doi:10.1016/s0300-9084(03)00089-0 · Cited by 36 · see citing works

Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-α induced morphological change of human endothelial cells in Vitro

Nelimarkka, L. O., Nikkari, S. T., Ravanti, L., Kähäri, V., & Järveläinen, H. (1998) · Matrix Biology · doi:10.1016/s0945-053x(98)90082-8 · Cited by 35 · see citing works

Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia

Yang, F., Suo, Y., Chen, D., & Li, T. (2016) · BioScience Trends · doi:10.5582/bst.2016.01056 · Cited by 35 · see citing works

The vascular origin of hematopoietic cells

Adamo, L., & García‐Cardeña, G. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.09.008 · Cited by 32 · see citing works

Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway

Shi, X., Guan, Y.-H., Jiang, S., Li, T., Sun, B., & Huan, C. (2018) · Archives of Medical Science · doi:10.5114/aoms.2018.74026 · Cited by 31 · see citing works

Increased plasma concentration of nitric oxide in type 2 diabetes but not in nondiabetic individuals with insulin resistance

Chien, W., Yang, K., Eng, H.-L., Hu, Y.-H., Lee, P. Y., Wang, S., & Wang, P. W. (2005) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70168-4 · Cited by 30 · see citing works

Peroxisome proliferator-activated receptors as therapeutic targets in inflammation**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

Plutzky, J. (2003) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.08.017 · Cited by 31 · see citing works

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1

Fledderus, J., Vanchin, B., Rots, M. G., & Krenning, G. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11020103 · Cited by 31 · see citing works

Inflammation-dependent thrombosis

Daniel, D. M. (2005) · Frontiers in bioscience · doi:10.2741/1732 · Cited by 30 · see citing works

Human cytomegalovirus immediate early proteins upregulate endothelial p53 function

Wang, J., Marker, P. H., Belcher, J. D., Wilcken, D. E. L., Burns, L. J., Vercellotti, G. M., & Wang, X. L. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01604-5 · Cited by 30 · see citing works

Animal models of erectile dysfunction

Kapoor, M. S., Khan, S. A., Gupta, S., Choudhary, R., & Bodakhe, S. H. (2015) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2015.07.013 · Cited by 29 · see citing works

Interrelation between inflammation, thrombosis, and neuroprotection in cerebral ischemia

van der Spuy, W. J., & Pretorius, E. (2012) · Reviews in the Neurosciences · doi:10.1515/revneuro-2012-0028 · Cited by 29 · see citing works

Mouse Model of Erectile Dysfunction Due to Diet-Induced Diabetes Mellitus

Xie, D., Odronic, S. I., Wu, F., Pippen, A. M., Donatucci, C. F., & Annex, B. H. (2007) · Urology · doi:10.1016/j.urology.2007.02.060 · Cited by 29 · see citing works

Cardiovascular Effects of Tibolone: A Selective Tissue Estrogenic Activity Regulator

Campisi, R., & Marengo, F. D. (2007) · Cardiovascular Drug Reviews · doi:10.1111/j.1527-3466.2007.00007.x · Cited by 29 · see citing works

Endothelial Dysfunction and Atherosclerosis

Gimbrone, M. A. (1989) · Journal of Cardiac Surgery · doi:10.1111/j.1540-8191.1989.tb00275.x · Cited by 34 · see citing works

Vascular endothelium – Gatekeeper of vessel health

Cahill, P. A., & Redmond, E. M. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.03.007 · Cited by 518 · see citing works

Vascular Endothelium: An Integrator of Pathophysiologic Stimuli in Cardiovascular Disease

Gimbrone, M. A. (1995) · Springer eBooks · doi:10.1007/978-1-4615-1959-1_14 · Cited by 1 · see citing works

Section Review Cardiovascular & Renal: Endothelium and atherosclerosis: monocyte accumulation as a target for therapeutic intervention

Saxena, U., & Wölle, J. (1996) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.5.11.1487

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

Gimbrone, M. A., & García‐Cardeña, G. (2016) · Circulation Research · doi:10.1161/circresaha.115.306301 · Cited by 3,554 · see citing works