Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression Implications for pathophysiology of DST nonsuppression
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Dysfunction of the hypothalamic-pituitary-adrenal axis with elevated plasma cortisol levels is characteristic of major depressive disorder.
“It is well established that dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis with elevated plasma cortisol levels is characteristic of MDD [56].”
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Self-citation
- Authors
- Holsboer, F., von Bardeleben, U., Wiedemann, K., Müller, O. A., & Stalla, G. K.
- Affiliations
- Johannes Gutenberg University Mainz (DE)
- Ludwig-Maximilians-Universität München (DE)
- Corresponding author
- Holsboer, F.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1987-02
- Volume
- 22
- Issue
- 2
- Pages
- 228-234
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1979581115
- Cited by
- 221
- References
- 13
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 4 · 2016: 1 · 2015: 6 · 2014: 1 · 2013: 7 · 2012: 11
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- corticotropin-releasing factor, dexamethasone suppression test, depression, hypothalamic-pituitary-adrenal axis, glucocorticoid feedback, serial assessment, depression pathophysiology
- MeSH terms
- Adrenocorticotropic Hormone, Adult, Bipolar Disorder, Corticotropin-Releasing Hormone, Depressive Disorder, Dexamethasone, Female, Humans, Hydrocortisone, Hypothalamo-Hypophyseal System, Male, Middle Aged, Pituitary-Adrenal System
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