Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial

Dunlop, Boadie W; Binder, Elisabeth B; Cubells, Joseph F; Goodman, Mark M; Kelley, Mary E; Kinkead, Becky; Kutner, Michael; Nemeroff, Charles B; Newport, D Jeffrey; Owens, Michael J; Pace, Thaddeus W W; Ritchie, James C; Rivera, Vivianne Aponte; Westen, Drew; Craighead, W Edward; Mayberg, Helen S

doi:10.1186/1745-6215-13-106

Cited by 136Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial

Open access

Dunlop, Boadie W, Binder, Elisabeth B, Cubells, Joseph F, Goodman, Mark M, Kelley, Mary E, Kinkead, Becky, Kutner, Michael, Nemeroff, Charles B +8 more·2012·Trials

DOI 10.1186/1745-6215-13-106PMC PMC3539869

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Limited controlled data exist to guide treatment choices for clinicians caring for patients with major depressive disorder (MDD). Although many putative predictors of treatment response have been reported, most were identified through retrospective analyses of existing datasets and very few have been replicated in a manner that can impact clinical practice. One major confound in previous studies examining predictors of treatment response is the patient's treatment history, which may affect both the predictor of interest and treatment outcomes. Moreover, prior treatment history provides an important source of selection bias, thereby limiting generalizability. Consequently, we initiated a randomized clinical trial designed to identify factors that moderate response to three treatments for MDD among patients never treated previously for the condition. METHODS/DESIGN: Treatment-naïve adults aged 18 to 65 years with moderate-to-severe, non-psychotic MDD are randomized equally to one of three 12-week treatment arms: (1) cognitive behavior therapy (CBT, 16 sessions); (2) duloxetine (30-60 mg/d); or (3) escitalopram (10-20 mg/d). Prior to randomization, patients undergo multiple assessments, including resting state functional magnetic resonance imaging (fMRI), immune markers, DNA and gene expression products, and dexamethasone-corticotropin-releasing hormone (Dex/CRH) testing. Prior to or shortly after randomization, patients also complete a comprehensive personality assessment. Repeat assessment of the biological measures (fMRI, immune markers, and gene expression products) occurs at an early time-point in treatment, and upon completion of 12-week treatment, when a second Dex/CRH test is also conducted. Patients remitting by the end of this acute treatment phase are then eligible to enter a 21-month follow-up phase, with quarterly visits to monitor for recurrence. Non-remitters are offered augmentation treatment for a second 12-week course of treatment, during which they receive a combination of CBT and antidepressant medication. Predictors of the primary outcome, remission, will be identified for overall and treatment-specific effects, and a statistical model incorporating multiple predictors will be developed to predict outcomes. DISCUSSION: The PReDICT study's evaluation of biological, psychological, and clinical factors that may differentially impact treatment outcomes represents a sizeable step toward developing personalized treatments for MDD. Identified predictors should help guide the selection of initial treatments, and identify those patients most vulnerable to recurrence, who thus warrant maintenance or combination treatments to achieve and maintain wellness.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1186/1745-6215-13-106

Cites

157 of 157 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Staging models identify where an individual lies along a continuum of risk for illness progression and extension and aid in reviewing the person's needs for intervention, including early intervention.
“They identify where an individual lies along a continuum of risk for illness progression (of the depressive illness or its underlying pathophysiology) and extension (additional complications beyond the syndrome of depression) 484,485 (Figure 8) and aid in reviewing the person's needs for intervention, including early intervention.”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [484]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,588 · see citing works
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,406 · see citing works
Regression shrinkage and selection via the lasso
Tibshirani, R. (1996) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1996.tb02080.x · Cited by 51,482 · see citing works
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
Classification and Regression Trees.
Gordon, A. D., Breiman, L., Friedman, J. H., Olshen, R. A., & Stone, C. J. (1984) · Biometrics · doi:10.2307/2530946 · Cited by 23,834 · see citing works
Classification and Regression Trees.
Ryzin, J. V., Breiman, L., Friedman, J. H., Olshen, R. A., & Stone, C. J. (1986) · Journal of the American Statistical Association · doi:10.2307/2288003 · Cited by 21,028 · see citing works
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391 · see citing works
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962 · see citing works
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455 · see citing works
World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects
Cook, R. J., Dickens, B. M., & Fathalla, M. F. (2003) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199241323.003.0025 · Cited by 10,813 · see citing works
Cognitive Therapy for Depression
(2012) · PsycEXTRA Dataset · doi:10.1037/e675542012-001 · Cited by 9,678 · see citing works
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676 · see citing works
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works
Development of a Rating Scale for Primary Depressive Illness
Hamilton, M. (1967) · British Journal of Social and Clinical Psychology · doi:10.1111/j.2044-8260.1967.tb00530.x · Cited by 8,410 · see citing works
Selective Cortical Undercutting As a Means of Modifying and Studying Frontal Lobe Function in Man
Scoville, W. B. (1949) · Journal of neurosurgery · doi:10.3171/jns.1949.6.1.0065 · Cited by 7,373 · see citing works
Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond
Pencina, M. J., D' Agostino, R. B., D' Agostino, R. B., & Vasan, R. S. (2008) · Statistics in Medicine · doi:10.1002/sim.2929 · Cited by 6,493 · see citing works
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358 · see citing works
The will and the ways: Development and validation of an individual-differences measure of hope.
Snyder, C. R. R., Harris, C., Anderson, J. R., Holleran, S. A., Irving, L. M., Sigmon, S. T., Yoshinobu, L., Gibb, J., Langelle, C., & Harney, P. (1991) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.60.4.570 · Cited by 4,765 · see citing works
A Meta-Analysis of Cytokines in Major Depression
Dowlati, Y., Herrmann, N., Swardfager, W., Liu, H., Sham, L., Reim, E. K., & Lanctôt, K. L. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.033 · Cited by 4,729 · see citing works
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685 · see citing works
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
Trivedi, M. H., Rush, A. J., Wisniewski, S. R., Nierenberg, A. A., Warden, D., Ritz, L., Norquist, G., Howland, R. H., Lebowitz, B., McGrath, P. J., et al. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.28 · Cited by 3,879 · see citing works
The 16-item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression
Rush, A. J., Trivedi, M. H., Ibrahim, H. M., Carmody, T. J., Arnow, B., Klein, D. N., Markowitz, J. C., Ninan, P. T., Kornstein, S., Manber, R., et al. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01866-8 · Cited by 3,829 · see citing works
The will and the ways: Development and validation of an individual-differences measure of hope.
Snyder, C. R., Harris, C., Anderson, J. R., Holleran, S. A., Irving, L. M., Sigmon, S. T., Yoshinobu, L., Gibb, J., Langelle, C., & Harney, P. (1991) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.60.4.570 · Cited by 3,774 · see citing works
Regression Shrinkage and Selection via The Lasso: A Retrospective
Tibshirani, R. J. (2011) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/j.1467-9868.2011.00771.x · Cited by 3,601 · see citing works
Investigations into resting-state connectivity using independent component analysis
Beckmann, C. F., DeLuca, M., Devlin, J. T., & Smith, S. M. (2005) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2005.1634 · Cited by 3,398 · see citing works
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
Bentley, S. D., Chater, K. F., Cerdeño-Tárraga, A. M., Challis, G. L., Thomson, N. R., James, K., Harris, D. E., Quail, M. A., Kieser, H. M., Harper, D., et al. (2002) · Nature · doi:10.1038/417141a · Cited by 3,226 · see citing works
The TIMI Risk Score for Unstable Angina/Non–ST Elevation MI
Antman, E. M., Cohen, M. C., Bernink, P. J. L. M., McCabe, C. H., Horacek, T., Papuchis, G., Mautner, B., Corbalán, R., Radley, D. R., & Braunwald, E. (2000) · JAMA · doi:10.1001/jama.284.7.835 · Cited by 3,221 · see citing works
Cytokines sing the blues: inflammation and the pathogenesis of depression
Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009 · see citing works
Assessing the impact of life changes: Development of the Life Experiences Survey.
Sarason, I. G., Johnson, J. H., & Siegel, J. M. (1978) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.46.5.932 · Cited by 2,788 · see citing works
Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis.
Howren, M. B., Lamkin, D. M., & Suls, J. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181907c1b · Cited by 2,766 · see citing works
Resting-State Functional Connectivity in Major Depression: Abnormally Increased Contributions from Subgenual Cingulate Cortex and Thalamus
Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214 · see citing works
Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
Drevets, W. C., Price, J. L., & Furey, M. L. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0189-x · Cited by 2,209 · cited 3× · see citing works
“Imaging predictors have included pre-treatment patterns of regional glucose metabolism and blood flow measured with positron emission tomography (PET) [36], as well as structural and functional magnetic resonance imaging (fMRI) studies [37].”
The Corticosteroid Receptor Hypothesis of Depression
Holsboer, F. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00159-7 · Cited by 2,181 · see citing works
Untitled work
Wilamowska (2010) · doi:10.1001/archpsyc.1988.01800320058007 · Cited by 2,115 · see citing works
Conceptualization and Rationale for Consensus Definitions of Terms in Major Depressive Disorder: Remission, Recovery, Relapse, and Recurrence
Frank, E. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810330075011 · Cited by 1,959 · cited 1× · see citing works
“Although it is widely considered that current interventions benefit approximately 60% of MDD patients, only about 30% to 40% of patients show full remission of their symptoms as defined by the MacArthur criteria (for example, a 17-item Hamilton Depression Rating Scale (HDRS) score <8) [14,15].”
Untitled work
(1993) · PubMed · Cited by 1,900 · see citing works
Presentation of multivariate data for clinical use: The Framingham Study risk score functions
SULLIVAN, L. M., Massaro, J. M., & D’Agostino, R. B. (2004) · Statistics in Medicine · doi:10.1002/sim.1742 · Cited by 1,756 · see citing works
The Risk for Early-Adulthood Anxiety and Depressive Disorders in Adolescents With Anxiety and Depressive Disorders
Pine, D. S., Cohen, P., Gurley, D., Brook, J., & Ma, Y. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.1.56 · Cited by 1,753 · see citing works
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
Cipriani, A., Furukawa, T. A., Salanti, G., Geddes, J. R., Higgins, J. P., Churchill, R., Watanabe, N., Nakagawa, A., Omori, I. M., McGuire, H., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60046-5 · Cited by 1,654 · see citing works
The Longitudinal Interval Follow-up Evaluation: A Comprehensive Method for Assessing Outcome in Prospective Longitudinal Studies
Keller, M. B. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800180050009 · Cited by 1,643 · see citing works
The impact of daily stress on health and mood: psychological and social resources as mediators
DeLongis, A., Folkman, S., & Lazarus, R. S. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.3.486 · Cited by 1,621 · cited 1× · see citing works
“The self-report Goals scale [125] and Combined Hassles and Uplifts scale [126] assess current levels of hopelessness and frustration and are collected at baseline and at intervals throughout the acute and follow-up phases.”
The impact of daily stress on health and mood: Psychological and social resources as mediators.
DeLongis, A., Folkman, S., & Lazarus, R. S. (1988) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.54.3.486 · Cited by 1,621 · see citing works
Validity of the Childhood Trauma Questionnaire in an Adolescent Psychiatric Population
BERNSTEIN, D. P., AHLUVALIA, T., POGGE, D., & HANDELSMAN, L. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199703000-00012 · Cited by 1,574 · see citing works
Clinical Global Impression
Guy, W. L. (2025) · Springer Reference Medizin · doi:10.1007/978-3-662-65186-5_300379 · Cited by 1,441 · see citing works
Comments on ‘Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond’ by M. J. Pencina, R. B. D'Agostino Sr, R. B. D'Agostino Jr, R. S. Vasan, Statistics in Medicine (DOI: 10.1002/sim.2929)
Greenland, P. (2007) · Statistics in Medicine · doi:10.1002/sim.2976 · Cited by 1,300 · see citing works
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297 · see citing works
Handbook of Psychiatric Measures
Salzman, C. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.8.1343 · Cited by 1,172 · see citing works
Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment
Mayberg, H. S. (2003) · British Medical Bulletin · doi:10.1093/bmb/65.1.193 · Cited by 1,166 · cited 4× · see citing works
“regional glucose metabolism and blood flow measured with positron emission tomography (PET) [36], as well as”
InfluentialSelf-citation
Paroxetine for the prevention of depression induced by high-dose interferon alfa.
Musselman, D. L., Lawson, D. H., Gumnick, J. F., Manatunga, A. K., Penna, S., Goodkin, R. S., Greiner, K., Nemeroff, C. B., & Miller, A. H. (2001) · New England Journal of Medicine · doi:10.1056/nejm200103293441303 · Cited by 1,120 · see citing works
Self-citation
A Guide to Treatments that Work
Nathan, P. E., & Gorman, J. M. (2007) · Oxford University Press eBooks · doi:10.1093/med/9780195304145.001.0001 · Cited by 1,082 · see citing works
The International Personality Disorder Examination: The World Health Organization/Alcohol, Drug Abuse, and Mental Health Administration International Pilot Study of Personality Disorders
Loranger, A. W. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950030051005 · Cited by 1,069 · see citing works
Risk for recurrence in depression
Burcusa, S. L., & Iacono, W. G. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.02.005 · Cited by 1,023 · see citing works
Cognitive Therapy vs Medications in the Treatment of Moderate to Severe Depression
DeRubeis, R. J., Hollon, S. D., Amsterdam, J. D., Shelton, R. C., Young, P. R., Salomon, R. M., O’Reardon, J. P., Lovett, M. L., Gladis, M. M., Brown, L. L., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.409 · Cited by 989 · see citing works
Interleukin (IL)-6, Tumour Necrosis Factor Alpha (TNF-α) and Soluble Interleukin-2 Receptors (SIL-2R) Are Elevated in Patients with Major Depressive Disorder: A Meta-Analysis and Meta-Regression
Liu, Y., Ho, R. C.-M., & Mak, A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.08.003 · Cited by 948 · see citing works
Difference in treatment outcome in outpatients with anxious versus nonanxious depression: A STAR*D report
Fava, M., Rush, A. J., Alpert, J. E., Balasubramani, G. K., Wisniewski, S. R., Carmin, C. N., Biggs, M. M., Zisook, S., Leuchter, A., Howland, R., et al. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111868 · Cited by 927 · see citing works
Recurrence after recovery from major depressive disorder during 15 years of observational follow-up
Mueller, T. I., Leon, A. C., Keller, M. B., Solomon, D. A., Endicott, J., Coryell, W., Warshaw, M., & Maser, J. D. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.7.1000 · Cited by 897 · see citing works
Mood and the mundane: Relations between daily life events and self-reported mood.
Clark, L. A., & Watson, D. (1988) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.54.2.296 · Cited by 852 · see citing works
Handbook of Psychiatric Measures
Rush, A. J., First, M. B., & Blacker, D. (2000) · Medical Entomology and Zoology · Cited by 846 · see citing works
Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma
Nemeroff, C. B., Heim, C. M., Thase, M. E., Klein, D. N., Rush, A. J., Schatzberg, A. F., Ninan, P. T., McCullough, J. P., Weiss, P. M., Dunner, D. L., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2336126100 · Cited by 829 · see citing works
Self-citation
Depression and Risk of Stroke Morbidity and Mortality: A Meta-analysis and Systematic Review
Pan, A., Sun, Q., Okereke, O. I., Rexrode, K. M., & Hu, F. B. (2011) · JAMA · doi:10.1001/jama.2011.1282 · Cited by 819 · see citing works
Subthreshold Depression in Adolescence and Mental Health Outcomes in Adulthood
Fergusson, D. M., Horwood, L. J., Ridder, E. M., & Beautrais, A. L. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.1.66 · Cited by 792 · see citing works
Activity and Connectivity of Brain Mood Regulating Circuit in Depression: A Functional Magnetic Resonance Study
Anand, A., Li, Y., Wang, Y., Wu, J., Gao, S., Bukhari, L., Mathews, V. P., Kalnin, A., & Lowe, M. J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.02.021 · Cited by 787 · see citing works
Mood and the mundane: Relations between daily life events and self-reported mood.
Clark, L. A., & Watson, D. (1988) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.54.2.296 · Cited by 784 · cited 1× · see citing works
“The Positive and Negative Affective Scale will be administered before and after the scanning session to assess emotional states at the time of the fMRI [88].”
A prospective 12-year study of subsyndromal and syndromal depressive symptoms in unipolar major depressive disorders
Judd, L. L., Akiskal, H. S., Maser, J. D., Zeller, P. J., Endicott, J., Coryell, W., Paulus, M. P., Kunovac, J. L., Leon, A. C., Mueller, T. I., et al. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.694 · Cited by 775 · see citing works
Depressed Affect, Hopelessness, and the Risk of Ischemic Heart Disease in a Cohort of U.S. Adults
Anda, R. F., Williamson, D. F., Jones, D., Macera, C., Eaker, E. D., Glassman, A. H., & Marks, J. S. (1993) · Epidemiology · doi:10.1097/00001648-199307000-00003 · Cited by 770 · see citing works
Effect of compassion meditation on neuroendocrine, innate immune and behavioral responses to psychosocial stress
Pace, T. W. W., Negi, L. T., Adame, D. D., Cole, S. P., Sivilli, T. I., Brown, T. D., Issa, M. J., & Raison, C. L. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.08.011 · Cited by 748 · cited 1× · see citing works
“The mean inter- and intra-assay coefficients of variation for control samples in this assay are reliably 10% or less [116].”
Self-citation
Depressive disorders and immunity: 20 years of progress and discovery
Irwin, M. R., & Miller, A. H. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.01.010 · Cited by 676 · see citing works
The combined dexamethasone/CRH test: A refined laboratory test for psychiatric disorders
Heuser, I., Yassouridis, A., & Holsboer, F. (1994) · Journal of Psychiatric Research · doi:10.1016/0022-3956(94)90017-5 · Cited by 662 · see citing works
Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression
Johansen-Berg, H., Gutman, D. A., Behrens, T. E. J., Matthews, P. M., Rushworth, M. F. S., Katz, E., Lozano, A. M., & Mayberg, H. S. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm167 · Cited by 561 · see citing works
Self-citation
Personality disorder and the outcome of depression: Meta-analysis of published studies
Newton-Howes, G., Tyrer, P., & Johnson, T. (2006) · British Journal of Psychiatry · doi:10.1192/bjp.188.1.13 · Cited by 537 · see citing works
Health Care Costs of Primary Care Patients With Recognized Depression
Simon, G. E. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950220060012 · Cited by 520 · see citing works
World Medical Association. World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects
(2004) · Journal international de bioéthique et d éthique des sciences · doi:10.3917/jib.151.0124 · Cited by 497 · see citing works
Development and reliability of a structured interview guide for the Montgomery Asberg Depression Rating Scale (SIGMA).
Williams, J. B. W., & Kobak, K. A. (2008) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.032532 · Cited by 463 · see citing works
Residual symptoms after remission of major depressive disorder with citalopram and risk of relapse: a STAR*D report
Nierenberg, A. A., Husain, M. M., Trivedi, M. H., Fava, M., Warden, D., Wisniewski, S. R., Miyahara, S., & Rush, A. J. (2010) · Psychological Medicine · doi:10.1017/s0033291709006011 · Cited by 458 · see citing works
CYP2D6 and CYP2C19 genotype‐based dose recommendations for antidepressants: a first step towards subpopulation‐specific dosages
Kirchheiner, J., Brøsen, K., Dahl, M., Gram, L. F., Kasper, S. F., Roots, I., Sjöqvist, F., Spina, E., & Brockmöller, J. (2001) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2001.00299.x · Cited by 422 · see citing works
Disease state prediction from resting state functional connectivity
Craddock, R. C., Holtzheimer, P. E., Hu, X. P., & Mayberg, H. S. (2009) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22159 · Cited by 411 · see citing works
Self-citation
Codes and Declarations
(2002) · Nursing Ethics · doi:10.1191/0969733002ne486xx · Cited by 395 · see citing works
Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications
Alesci, S., Martinez, P. E., Kelkar, S., Ilias, I., Ronsaville, D. S., Listwak, S. J., Ayala, A. R., Licinio, J., Gold, H. K., Kling, M. A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1667 · Cited by 372 · see citing works
Personalized Medicine for Depression: Can We Match Patients With Treatments?
Simon, G. E., & Perlis, R. H. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09111680 · Cited by 365 · cited 2× · see citing works
“Previous efforts attempting to identify predictors of treatment response have typically been post-hoc analyses of datasets designed to test other hypotheses [18].”
Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project
Uher, R., Perroud, N. A., Ng, M., Hauser, J., Henigsberg, N., Maier, W., Mors, O. N., Placentino, A., Rietschel, M., Souery, D., et al. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09070932 · Cited by 350 · see citing works
The temporal relation of adherence and alliance to symptom change in cognitive therapy for depression.
Feeley, M., DeRubeis, R. J., & Gelfand, L. A. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.4.578 · Cited by 349 · see citing works
Catecholamine Metabolism, Depressive Illness, and Drug Response
Maas, J. W. (1972) · Archives of General Psychiatry · doi:10.1001/archpsyc.1972.01750210060012 · Cited by 342 · see citing works
Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?
Ising, M., Horstmann, S., Kloiber, S., Lucae, S., Binder, E. B., Kern, N., Künzel, H. E., Pfennig, A., Uhr, M., & Holsboer, F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.039 · Cited by 341 · cited 1× · see citing works
“Biochemical and endocrinology predictors include hypothalamic-pituitary-adrenal (HPA) axis measures [33],”
Self-citation
Cytokines and Glucocorticoid Receptor Signaling
Pace, T. W. W., & Miller, A. H. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04984.x · Cited by 339 · see citing works
Self-citation
Inflammatory markers in late-life depression: Results from a population-based study
Bremmer, M. A., Beekman, A. T. F., Deeg, D. J. H., Penninx, B. W. J. H., Dik, M. G., Hack, C. E., & Hoogendijk, W. J. G. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.07.002 · Cited by 326 · see citing works
Are Antidepressant Drugs That Combine Serotonergic and Noradrenergic Mechanisms of Action More Effective Than the Selective Serotonin Reuptake Inhibitors in Treating Major Depressive Disorder? A Meta-analysis of Studies of Newer Agents
Papakostas, G. I., Thase, M. E., Fava, M., Nelson, J. C., & Shelton, R. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.027 · Cited by 308 · see citing works
A Genomewide Association Study Points to Multiple Loci That Predict Antidepressant Drug Treatment Outcome in Depression
Ising, M., Lucae, S., Binder, E. B., Bettecken, T., Uhr, M., Ripke, S., Kohli, M. A., Hennings, J. M., Horstmann, S., Kloiber, S. M., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.95 · Cited by 306 · see citing works
Self-citation
Microstructural White Matter Abnormalities and Remission of Geriatric Depression
Alexopoulos, G. S., Murphy, C. F., Gunning‐Dixon, F. M., Latoussakis, V., Kanellopoulos, D., Klimstra, S., Lim, K. O., & Hoptman, M. J. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07050744 · Cited by 297 · see citing works
Standardizing the Hamilton Depression Rating Scale: past, present, and future
Williams, J. B. W. (2001) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf03035120 · Cited by 294 · see citing works
Treatment of mood disorders
Nemeroff, C. B., & Owens, M. J. (2002) · Nature Neuroscience · doi:10.1038/nn943 · Cited by 282 · see citing works
Self-citation
Clinical management--imipramine/placebo administration manual. NIMH Treatment of Depression Collaborative Research Program.
FAWCETT, J. A., Epstein, P., Fiester, S. J., Elkin, I., & Autry, J. H. (1987) · PubMed · Cited by 273 · see citing works
The combined dexamethasone/CRH test as a potential surrogate marker in depression
Ising, M., Kunzel, H. E., Binder, E. B., Nickel, T., Modell, S., & Holsboer, F. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.03.014 · Cited by 268 · see citing works
Self-citation
Long-term economic costs of psychological problems during childhood
Smith, J. P., & Smith, G. C. (2010) · Social Science & Medicine · doi:10.1016/j.socscimed.2010.02.046 · Cited by 264 · see citing works
Effect of childhood trauma on adult depression and neuroendocrine function: sex-specific moderation by CRH receptor 1 gene
Heim, C. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.041.2009 · Cited by 245 · see citing works
Depressive Symptoms and the Risk of Type 2 Diabetes
Golden, S. H., Williams, J. E., Ford, D. E., Yeh, H., Sanford, C. P., Nieto, F. J., & Brancati, F. L. (2004) · Diabetes Care · doi:10.2337/diacare.27.2.429 · Cited by 233 · see citing works
Relationship of Personality Disorders to the Course of Major Depressive Disorder in a Nationally Representative Sample
Skodol, A. E., Grilo, C. M., Keyes, K. M., Geier, T., Grant, B. F., & Hasin, D. S. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10050695 · Cited by 225 · see citing works
Electroencephalographic and perceptual asymmetry differences between responders and nonresponders to an SSRI antidepressant21Data from two treatment protocols were combined so as to yield sufficient samples of female and male fluoxetine responders and nonresponders. With the exception of the initial placebo period in one study, the treatment protocols were comparable in terms of both fluoxetine doses and the raters evaluating treatment response. Most importantly, the differences between fluoxetine responders and nonresponders reported for the total samples were also evident when only the data for the placebo-controlled protocol were analyzed; however, the larger total sample allowed us to also take patient gender into account.22The 18 healthy women were screened for psychopathology using a structured interview schedule and were excluded if they had a hearing loss, substance abuse, a history of head trauma, or other neurologic disorder. They did not differ significantly from the female patients in education (mean = 15.8, SD = 1.3) or handedness (LQ = 84.7, SD = 20.6), but they were somewhat younger than the female patients [mean age = 27.6, SD = 6.9;t(35) = 3.21,p = .001]. Age was not, however, related to perceptual asymmetry scores of either female patients (r = −.01, ns) or male patients (r = −.02, ns) on the fused words test. Nor was age significantly correlated with alpha asymmetry scores of female patients (r = −.09, ns) or male patients (r = .11, ns).
Bruder, G. E., Stewart, J. W., Tenke, C. E., McGrath, P. J., Leite, P., Bhattacharya, N., & Quitkin, F. M. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01016-7 · Cited by 223 · see citing works
Serial assessment of corticotropin-releasing hormone response after dexamethasone in depression Implications for pathophysiology of DST nonsuppression
Holsboer, F., von Bardeleben, U., Wiedemann, K., Müller, O. A., & Stalla, G. K. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90237-x · Cited by 221 · see citing works
Efficacy of escitalopram in the treatment of major depressive disorder compared with conventional selective serotonin reuptake inhibitors and venlafaxine XR: a meta-analysis
Kennedy, S. H., Andersen, H. F., & Lam, R. W. M. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0615 · Cited by 216 · see citing works
Assessment of the Dexamethasone/CRH Test as a State-Dependent Marker for Hypothalamic-Pituitary-Adrenal (HPA) Axis Abnormalities in Major Depressive Episode: A Multicenter Study
Kunugi, H., Ida, I., Owashi, T., Kimura, M., Inoue, Y., Nakagawa, S., Yabana, T., Urushibara, T., Kanai, R., Aihara, M., et al. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300868 · Cited by 200 · see citing works
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients
Menke, A., Arloth, J., Pütz, B., Weber, P., Klengel, T., Mehta, D., Gonik, M., Rex-Haffner, M., Rubel, J., Uhr, M., et al. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.331 · Cited by 177 · see citing works
Self-citation
Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: Results of the BRITE-MD study
Leuchter, A. F., Cook, I. A., Marangell, L. B., Gilmer, W. S., Burgoyne, K. S., Howland, R. H., Trivedi, M. H., Zisook, S., Jain, R., McCracken, J. T., et al. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2009.06.004 · Cited by 175 · see citing works
Reports of the childhood home environment in early-onset dysthymia and episodic major depression.
Lizardi, H., Klein, D. N., Ouimette, P. C., Riso, L. P., Anderson, R. L., & Donaldson, S. K. (1995) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.104.1.132 · Cited by 174 · see citing works
Patient Preference as a Moderator of Outcome for Chronic Forms of Major Depressive Disorder Treated With Nefazodone, Cognitive Behavioral Analysis System of Psychotherapy, or Their Combination
Kocsis, J. H., Leon, A. C., Markowitz, J. C., Manber, R., Arnow, B. A., Klein, D. N., & Thase, M. E. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04371 · Cited by 172 · see citing works
Personality and Differential Treatment Response in Major Depression: A Randomized Controlled Trial Comparing Cognitive-Behavioural Therapy and Pharmacotherapy
Bagby, R. M., Quilty, L. C., Segal, Z. V., McBride, C., Kennedy, S. H., & Costa, P. T. (2008) · The Canadian Journal of Psychiatry · doi:10.1177/070674370805300605 · Cited by 172 · see citing works
Personality and Depression
Bagby, R. M., Quilty, L. C., & Ryder, A. G. (2008) · The Canadian Journal of Psychiatry · doi:10.1177/070674370805300104 · Cited by 166 · see citing works
Comprehensive Analysis of Remission (COMPARE) with Venlafaxine versus SSRIs
Nemeroff, C. B., Entsuah, R., Benattia, I., Demitrack, M. A., Sloan, D. M., & Thase, M. E. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.027 · Cited by 161 · see citing works
Self-citation
Depression and C-Reactive Protein: Population-Based Health 2000 Study
Elovainio, M., Aalto, A.-M., Kivimäki, M., Pirkola, S., Sundvall, J., Lönnqvist, J., & Reunanen, A. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31819e333a · Cited by 157 · see citing works
Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder
Konarski, J. Z., Kennedy, S. H., Segal, Z. V., Lau, M. A., Bieling, P., McIntyre, R. S., & Mayberg, H. S. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0923 · Cited by 155 · see citing works
Self-citation
C-Reactive Protein Is Associated With Psychological Risk Factors of Cardiovascular Disease in Apparently Healthy Adults
Suarez, E. C. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000138281.73634.67 · Cited by 150 · see citing works
Neural modeling and functional brain imaging: an overview
Horwitz, B., Friston, K. J., & Taylor, J. G. (2000) · Neural Networks · doi:10.1016/s0893-6080(00)00062-9 · Cited by 146 · see citing works
Cardiovascular toxicity due to venlafaxine poisoning in adults: a review of 235 consecutive cases
Howell, C., Wilson, A. D., & Waring, W. S. (2007) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2007.02849.x · Cited by 144 · see citing works
Drug interactions with newer antidepressants: role of human cytochromes P450.
Greenblatt, D. J., Moltke, L. L., Harmatz, J. S., & Shader, R. I. (1998) · PubMed · Cited by 141 · see citing works
[Validation of the Spanish version of the Liebowitz social anxiety scale, social anxiety and distress scale and Sheehan disability inventory for the evaluation of social phobia].
Bobes, J., Badia, X. C., Luque, A., García, M., González, M. P., & Dal−Ré, R. (1999) · PubMed · Cited by 135 · see citing works
Personality diagnosis with the Shedler-Westen Assessment Procedure (SWAP): Integrating clinical and statistical measurement and prediction.
Westen, D., & Shedler, J. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.4.810 · Cited by 135 · see citing works
Self-citation
Differential Prediction of First Clinical Response to Serotonergic and Noradrenergic Antidepressants Using the Loudness Dependence of Auditory Evoked Potentials in Patients With Major Depressive Disorder
Juckel, G., Pogarell, O. M., Augustin, H., Mulert, C., Muller-Siecheneder, F., Frodl, T., Mavrogiorgou, P., & Hegerl, U. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0806 · Cited by 126 · see citing works
Comprehensive Analysis of Remission (COMPARE) with Venlafaxine versus SSRIs
Nemeroff, C. B., Entsuah, R., Benattia, I., Demitrack, M. A., Sloan, D. M., & Thase, M. E. (2010) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.8.4.foc592 · Cited by 126 · see citing works
Self-citation
‘It's not over when it's over’: persistent neurobiological abnormalities in recovered depressed patients
Bhagwagar, Z., & Cowen, P. J. (2008) · Psychological Medicine · doi:10.1017/s0033291707001250 · Cited by 124 · see citing works
Pharmacogenomics of antidepressant drugs.
Horstmann, S., & Binder, E. (2009) · Pharmacology and Therapeutics · doi:10.1016/j.pharmthera.2009.06.007 · Cited by 120 · see citing works
Self-citation
Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder
Leuchter, A. F., Cook, I. A., Gilmer, W. S., Marangell, L. B., Burgoyne, K. S., Howland, R. H., Trivedi, M. H., Zisook, S., Jain, R. K., D, M. F. M., et al. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2009.04.004 · Cited by 120 · see citing works
Efficacy of Bupropion and the Selective Serotonin Reuptake Inhibitors in the Treatment of Major Depressive Disorder With High Levels of Anxiety (Anxious Depression)
Papakostas, G. I., Stahl, S. M., Krishen, A., Seifert, C. A., Tucker, V. L., Goodale, E. P., & D, M. F. M. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0812 · Cited by 117 · see citing works
HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients
Binder, E. B., Kunzel, H. E., Nickel, T., Kern, N., Pfennig, A., Majer, M., Uhr, M., Ising, M., & Holsboer, F. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.08.018 · Cited by 116 · see citing works
Self-citation
Modeling relapse in unipolar depression: The effects of dysfunctional cognitions and personality disorders.
Ilardi, S. S., Craighead, W. E., & Evans, D. D. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.65.3.381 · Cited by 115 · see citing works
Self-citation
Modeling relapse in unipolar depression: The effects of dysfunctional cognitions and personality disorders
Ilardi, S. S., Craighead, W. E., & Evans, D. D. (1997) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.65.3.381 · Cited by 115 · see citing works
Self-citation
Efficacy of Duloxetine and Selective Serotonin Reuptake Inhibitors
Thase, M. E., Pritchett, Y., Ossanna, M. J., Swindle, R. W., Xu, J., & Detke, M. J. (2007) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31815a4412 · Cited by 113 · see citing works
Psychomotor slowing as a predictor of fluoxetine nonresponse in depressed outpatients
Taylor, B. P., Bruder, G. E., Stewart, J. W., McGrath, P. J., Halperin, J., Ehrlichman, H., & Quitkin, F. M. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.73 · Cited by 109 · see citing works
An Empirically Derived Taxonomy for Personality Diagnosis: Bridging Science and Practice in Conceptualizing Personality
Westen, D., Shedler, J., Bradley, B., & DeFife, J. A. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.11020274 · Cited by 106 · see citing works
Self-citation
Psychosocial Treatments for Major Depressive Disorder
Craighead, W. E., Sheets, E. S., Brosse, A. L., & Ilardi, S. S. (2007) · Oxford University Press eBooks · doi:10.1093/med:psych/9780195304145.003.0010 · Cited by 100 · see citing works
Self-citation
Magnetic resonance imaging and prediction of outcome in patients with major depressive disorder
MacQUEEN, G. M. (2009) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0945 · Cited by 92 · see citing works
The combined DEX-CRH test in treatment course and long-term outcome of major depression
Hatzinger, M., Hemmeter, U., Baumann, K., Brand, S., & Holsboer‐Trachsler, E. (2002) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(02)00021-3 · Cited by 90 · see citing works
Detecting low‐frequency functional connectivity in fMRI using a self‐organizing map (SOM) algorithm
Peltier, S. J., Polk, T. A., & Noll, D. C. (2003) · Human Brain Mapping · doi:10.1002/hbm.10144 · Cited by 87 · see citing works
Gene Expression Studies in Major Depression
Mehta, D., Menke, A., & Binder, E. B. (2010) · Current Psychiatry Reports · doi:10.1007/s11920-010-0100-3 · Cited by 87 · see citing works
Self-citation
Predictors of response to antidepressants
Nierenberg, A. A. (2003) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(02)00105-3 · Cited by 84 · see citing works
Depression beliefs, treatment preference, and outcomes in a randomized trial for major depressive disorder
Dunlop, B. W., Kelley, M. E., Mletzko, T., Velasquez, C. M., Craighead, W. E., & Mayberg, H. S. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.11.003 · Cited by 80 · see citing works
Self-citation
Exploratory structural equation modeling of resting-state fMRI: Applicability of group models to individual subjects
James, G. A., Kelley, M. E., Craddock, R. C., Holtzheimer, P. E., Dunlop, B. W., Nemeroff, C. B., Mayberg, H. S., & Hu, X. P. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.12.049 · Cited by 74 · see citing works
Self-citation
The DEX/CRH neuroendocrine test and the prediction of depressive relapse in remitted depressed outpatients
Aubry, J., Gervasoni, N., Osiek, C., Perret, G., Rossier, M. F., Bertschy, G., & Bondolfi, G. (2006) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2006.07.007 · Cited by 69 · see citing works
Estimates of Serotonin and Norepinephrine Transporter Inhibition in Depressed Patients Treated with Paroxetine or Venlafaxine
Owens, M. J., Krulewicz, S., Simon, J. S., Sheehan, D. V., Thase, M. E., Carpenter, D. J., Plott, S. J., & Nemeroff, C. B. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.47 · Cited by 68 · see citing works
Self-citation
Pharmacogenetics of antidepressant response
Keers, R., & Aitchison, K. J. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.186 · Cited by 66 · see citing works
Predictive Value of Symptoms of Atypical Depression
McGrath, P. J., Stewart, J. W., Harrison, W. M., Ocepek‐Welikson, K., Rabkin, J. G., NUNES, E. N., Wager, S., TRICAMO, E., Quitkin, F. M., & Klein, D. F. (1992) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199206000-00009 · Cited by 63 · see citing works
Paroxetine binding to the rat norepinephrine transporter in vivo
Owens, M. J., Knight, D. L., & Nemeroff, C. B. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00314-5 · Cited by 61 · see citing works
Self-citation
Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
Baer‐Dubowska, W., Majchrzak‐Celińska, A., & Cichocki, M. (2011) · Pharmacological Reports · doi:10.1016/s1734-1140(11)70498-4 · Cited by 60 · see citing works
Symptom Clusters as Predictors of Late Response to Antidepressant Treatment
Trivedi, M. H., Morris, D. W., Grannemann, B. D., & Mahadi, S. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0816 · Cited by 55 · see citing works
Genome-wide association studies of antidepressant outcome: A brief review
Laje, G., & McMahon, F. J. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.11.031 · Cited by 47 · see citing works
A Novel System for the Determination of Antidepressant Concentrations in Human Breast Milk
Hostetter, A. L., Stowe, Z. N., Cox, M. C., & Ritchie, J. (2004) · Therapeutic Drug Monitoring · doi:10.1097/00007691-200402000-00011 · Cited by 29 · see citing works
Self-citation
Dimensions of Personality and Personality Pathology: Factor Structure of the Shedler–Westen Assessment Procedure-II (SWAP-II)
Westen, D., Waller, N. G., Shedler, J., & Blagov, P. S. (2012) · Journal of Personality Disorders · doi:10.1521/pedi_2012_26_059 · Cited by 24 · see citing works
Self-citation
Impact of Antidepressant Treatment History on Clinical Outcomes in Placebo and Medication Treatment of Major Depression
Hunter, A. M., Cook, I. A., & Leuchter, A. F. (2010) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e3181faa474 · Cited by 21 · see citing works
Recurrence of MDD: A prospective study of personality pathology and cognitive distortions.
Craighead, W. E., Sheets, E. S., Craighead, L. W., & Madsen, J. W. (2010) · Personality Disorders Theory Research and Treatment · doi:10.1037/a0020456 · Cited by 20 · see citing works
Self-citation
Treatment Response in Depressed Patients with Enhanced Ca Mobilization Stimulated by Serotonin
Kusumi, I. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00149-4 · Cited by 19 · see citing works
Pharmacological Treatments for Unipolar Depression
Prendes-Alvarez, S., Schatzberg, A. F., & Nemeroff, C. B. (2015) · Oxford University Press eBooks · doi:10.1093/med:psych/9780199342211.003.0011 · Cited by 19 · see citing works
Self-citation
Data Modeling and Database Design
Umanath, N. S., & Scamell, R. W. (2007) · Cited by 16 · see citing works
Pharmacological Treatments for Unipolar Depression
Nemeroff, C. B., & Schatzberg, A. F. (2007) · Oxford University Press eBooks · doi:10.1093/med:psych/9780195304145.003.0009 · Cited by 14 · see citing works
Self-citation
[Critical study of reliability and validity of Beck's inventory measuring depression].
López, C., Esteban Chamorro, T., & Useros Serrano, E. (1976) · PubMed · Cited by 12 · see citing works
Direction and Challenges of National-based Mental Health Research - Focused on the Study of 「National Research Action Plan」 and 「NIMH Strategic Plan」 -
Lee, H.-K., & 김지은 (2013) · doi:10.22900/kphr.2013.39.2.014 · Cited by 6 · see citing works
Response to Treatment with Placebo, Medication or Psychotherapy in Severe Non- Psychotic Major Depressive Disorder
Dunlop, B. W., & Aaron, M. (2010) · Current Psychiatry Reviews · doi:10.2174/157340010790596526 · Cited by 5 · see citing works
Self-citation
Tolerability of the dexamethasone–corticotropin releasing hormone test in major depressive disorder
Dunlop, B. W., Betancourt, Y., Binder, E. B., Heim, C. C., Holsboer, F., Ising, M., McKenzie, M., Mletzko, T., Pfister, H., Nemeroff, C. B., et al. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.04.020 · Cited by 4 · see citing works
Self-citation
A comparison of fMRI and electrophysiology in the anesthetized macaque monkey
Disbrow, E. A., Roberts, T. P. L., Slutsky, D. A., Rowley, H. A., & Krubitzer, L. A. (2000) · NeuroImage · doi:10.1016/s1053-8119(00)91735-x · Cited by 2 · see citing works
Untitled work
Harrell, F., Jr. (1996) · doi:10.1002/(sici)1097-0258(19960229)15:4

Flagged first, then by citations

Research works printed but not linked: 2

First MB Spitzer RL Gibbon M Williams JB Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0) 1995 New York: Biometrics Research Department, New York State Psychiatric Institute
Concepcion G De la Cruz A Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition, (SCID-I/P), Spanish Translation 2005 New York: Biometrics Research: New York State Psychiatric Institute

Sorted by citations

Time for united action on depression: a Lancet–World Psychiatric Association Commission
Herrman, H., Patel, V., Kieling, C., Berk, M., Buchweitz, C., Cuijpers, P., Furukawa, T. A., Kessler, R. C., Kohrt, B. A., Maj, M., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02141-3 · Cited by 1,104 · see citing works
Self-citation
Psychological therapies for people with borderline personality disorder.
Stoffers-Winterling, J. M., Völlm, B. A., Rücker, G., Timmer, A., Huband, N., & Lieb, K. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005652.pub2 · Cited by 895 · see citing works
Toward a Neuroimaging Treatment Selection Biomarker for Major Depressive Disorder
McGrath, C. L., Kelley, M. E., Holtzheimer, P. E., Dunlop, B. W., Craighead, W. E., Franco, A. R., Craddock, R. C., & Mayberg, H. S. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.143 · Cited by 561 · see citing works
Self-citation
The personalized advantage index: translating research on prediction into individualized treatment recommendations. A demonstration
DeRubeis, R. J., Cohen, Z. D., Forand, N. R., Fournier, J. C., Gelfand, L. A., & Lorenzo-Luaces, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0083875 · Cited by 509 · see citing works
Treatment selection in depression.
Cohen, Z. D., & DeRubeis, R. J. (2018) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050817-084746 · Cited by 435 · see citing works
Psychological therapies for people with borderline personality disorder
Storebø, O. J., Stoffers-Winterling, J. M., Völlm, B. A., Kongerslev, M. T., Mattivi, J. T., Jørgensen, M. S., Faltinsen, E., Todorovac, A., Sales, C. P., Callesen, H. E., et al. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012955.pub2 · Cited by 450 · see citing works
Candidate biomarkers in psychiatric disorders: state of the field
Abi‐Dargham, A., Moeller, S. J., Ali, F., DeLorenzo, C., Domschke, K., Horga, G., Jutla, A., Kotov, R., Paulus, M. P., Rubio, J. M., et al. (2023) · World Psychiatry · doi:10.1002/wps.21078 · Cited by 390 · see citing works
Functional connectivity of the subcallosal cingulate cortex and differential outcomes to treatment with cognitive- behavioral therapy or antidepressant medication for major depressive disorder
Dunlop, B. W., Rajendra, J. K., Craighead, W. E., Kelley, M. E., McGrath, C. L., Choi, K. S., Kinkead, B., Nemeroff, C. B., & Mayberg, H. S. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16050518 · Cited by 342 · see citing works
“Studies The design of the Emory Predictors of Remission in Depression to Individual andCombinedTreatments (PReDICT) study has been published previously (39), and the clinical results of the trial are presented elsewhere (10).”
Self-citation
Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design
Trivedi, M. H., McGrath, P. J., Fava, M., Parsey, R. V., Kurian, B. T., Phillips, M. L., Oquendo, M. A., Bruder, G., Pizzagalli, D., Toups, M., et al. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2016.03.001 · Cited by 286 · see citing works
Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response
Syed, S. A., Beurel, E., Loewenstein, D., Lowell, J. A., Craighead, W. E., Dunlop, B. W., Mayberg, H. S., Dhabhar, F. S., Dietrich, W. D., Keane, R. W., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.08.001 · Cited by 212 · see citing works
Self-citation
Using patient self-reports to study heterogeneity of treatment effects in major depressive disorder
Kessler, R. C., van Loo, H. M., Wardenaar, K. J., Bossarte, R. M., Brenner, L. A., Ebert, D. D., de Jonge, P., Nierenberg, A. A., Rosellini, A. J., Sampson, N. A., et al. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016000020 · Cited by 193 · see citing works
Next-Generation Treatments for Mental Disorders
Insel, T. R. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004873 · Cited by 161 · see citing works
Treating major depression with yoga: A prospective, randomized, controlled pilot trial
Prathikanti, S., Rivera, R., Cochran, A., Tungol, J. G., Fayazmanesh, N., & Weinmann, E. (2017) · PLOS ONE · doi:10.1371/journal.pone.0173869 · Cited by 157 · see citing works
Sample size requirements for multivariate models to predict between-patient differences in best treatments of major depressive disorder
Luedtke, A., Sadikova, E., & Kessler, R. C. (2019) · Clinical Psychological Science · doi:10.1177/2167702618815466 · Cited by 143 · see citing works
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals
Amin, N., Liu, J., Bonnechère, B., MahmoudianDehkordi, S., Arnold, M., Batra, R., Chiou, Y., Fernandes, M., Ikram, M. A., Kraaij, R., et al. (2023) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.0685 · Cited by 153 · see citing works
Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study
Dunlop, B. W., Kelley, M. E., Aponte‐Rivera, V., Mletzko, T., Kinkead, B. L., Ritchie, J., Nemeroff, C. B., Craighead, W. E., Mayberg, H. S., & for the PReDICT Team (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16050517 · Cited by 139 · see citing works
Self-citation
Combination Psychotherapy and Antidepressant Medication Treatment for Depression: For Whom, When, and How
Craighead, W. E., & Dunlop, B. W. (2011) · Annual Review of Psychology · doi:10.1146/annurev.psych.121208.131653 · Cited by 129 · see citing works
Self-citation
Metabolomic and inflammatory signatures of symptom dimensions in major depression
Brydges, C. R., Bhattacharyya, S., Dehkordi, S. M., Milaneschi, Y., Penninx, B., Jansen, R., Kristal, B. S., Han, X., Arnold, M., Kastenmüller, G., et al. (2022) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2022.02.003 · Cited by 108 · see citing works
Self-citation
Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial
Gorka, S. M., Young, C. B., Klumpp, H., Kennedy, A. E., Francis, J., Ajilore, O., Langenecker, S. A., Shankman, S. A., Craske, M. G., Stein, M. B., et al. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0407-7 · Cited by 104 · see citing works
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature
Brydges, C. R., Fiehn, O., Mayberg, H. S., Schreiber, H. L., Dehkordi, S. M., Bhattacharyya, S., Cha, J., Choi, K. S., Craighead, W. E., Krishnan, R. R., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-99845-1 · Cited by 100 · see citing works
Self-citation
Clinical classification in mental health at the cross-roads: which direction next?
Hickie, I. B., Scott, J. L., Hermens, D. F., Scott, E. M., Naismith, S. L., Guastella, A. J., Glozier, N., & McGorry, P. D. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-125 · Cited by 88 · see citing works
Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation
López, J. P., Brivio, E., Santambrogio, A., Donno, C. D., Kos, A., Peters, M., Rost, N., Czamara, D., Brückl, T. M., Roeh, S., et al. (2021) · Science Advances · doi:10.1126/sciadv.abe4497 · Cited by 80 · see citing works
Self-citation
Neuroimaging for psychotherapy research: current trends.
Weingarten, C. P., & Strauman, T. J. (2015) · Psychotherapy Research · doi:10.1080/10503307.2014.883088 · Cited by 81 · see citing works
Effects of religiosity and spirituality on the treatment response in patients with depressive disorders
Kim, N., Huh, H.-J., & Chae, J. (2015) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2015.04.009 · Cited by 82 · see citing works
Biomarkers Predicting Antidepressant Treatment Response: How Can We Advance the Field?
Labermaier, C., Masana, M., & Müller, M. B. (2013) · Disease Markers · doi:10.1155/2013/984845 · Cited by 76 · see citing works
Gut microbiome-linked metabolites in the pathobiology of major depression with or without anxiety-a role for bile acids
MahmoudianDehkordi, S., Bhattacharyya, S., Brydges, C. R., Jia, W., Fiehn, O., Rush, A. J., Dunlop, B. W., & Kaddurah-Daouk, R. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.937906 · Cited by 75 · see citing works
Biomarkers for Psychiatric Disorders: Where Are We Standing?
Martins‐de‐Souza, D. (2013) · Disease Markers · doi:10.1155/2013/321071 · Cited by 73 · see citing works
Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression
Dunlop, B. W., LoParo, D., Kinkead, B. L., Mletzko, T., Cole, S. P., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.18091075 · Cited by 65 · see citing works
Self-citation
The neuroscience of depression: Implications for assessment and intervention
Singh, M. K., & Gotlib, I. H. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.08.008 · Cited by 70 · see citing works
Reconciling Variable Findings of White Matter Integrity in Major Depressive Disorder
Choi, K. S., Holtzheimer, P. E., Franco, A. R., Kelley, M. E., Dunlop, B. W., Hu, X. P., & Mayberg, H. S. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.345 · Cited by 66 · see citing works
Self-citation
Connectome signatures of neurocognitive abnormalities in euthymic bipolar I disorder
Ajilore, O., Vizueta, N., Walshaw, P. D., Zhan, L., Leow, A., & Altshuler, L. L. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.05.017 · Cited by 63 · see citing works
Shared and Unique Changes in Brain Connectivity Among Depressed Patients After Remission With Pharmacotherapy Versus Psychotherapy
Dunlop, B. W., Cha, J., Choi, K. S., Rajendra, J. K., Nemeroff, C. B., Craighead, W. E., & Mayberg, H. S. (2023) · American Journal of Psychiatry · doi:10.1176/appi.ajp.21070727 · Cited by 56 · see citing works
Self-citation
Optimizing Outcomes of Treatment-Resistant Depression in Older Adults (OPTIMUM): Study Design and Treatment Characteristics of the First 396 Participants Randomized
Cristancho, P., Lenard, E., Lenze, E. J., Miller, J. P., Brown, P. J., Roose, S. P., Montes-Garcia, C., Blumberger, D. M., Mulsant, B. H., Lavretsky, H., et al. (2019) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2019.04.005 · Cited by 54 · see citing works
Attenuation of Frontostriatal Connectivity During Reward Processing Predicts Response to Psychotherapy in Major Depressive Disorder
Walsh, E. C., Carl, H., Eisenlohr-Moul, T. A., Minkel, J. D., Crowther, A., Moore, T. M., Gibbs, D. E., Petty, C., Bizzell, J., Smoski, M. J., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.179 · Cited by 56 · see citing works
Circulating metabolites modulated by diet are associated with depression
van der Spek, A., Stewart, I. D., Kühnel, B., Pietzner, M., Alshehri, T., Gauß, K. F., Hysi, P. G., MahmoudianDehkordi, S., Heinken, A., Luik, A. I., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02180-2 · Cited by 58 · see citing works
Self-citation
Connectome-based models can predict early symptom improvement in major depressive disorder
Ju, Y., Horien, C. L., Chen, W., Guo, W., Lu, X., Sun, J., Dong, Q., Liu, B., Liu, J., Yan, D., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.04.028 · Cited by 51 · see citing works
Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein
O’Connell, C. P., Goldstein‐Piekarski, A. N., Nemeroff, C. B., Schatzberg, A. F., DeBattista, C., Carrillo‐Roa, T., Binder, E. B., Dunlop, B. W., Craighead, W. E., Mayberg, H. S., et al. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17020172 · Cited by 50 · see citing works
Self-citation
Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry
Kappelmann, N., Rein, M., Fietz, J., Mayberg, H. S., Craighead, W. E., Dunlop, B. W., Nemeroff, C. B., Keller, M. B., Klein, D. N., Arnow, B. A., et al. (2020) · BMC Medicine · doi:10.1186/s12916-020-01623-9 · Cited by 49 · see citing works
Self-citation
Combined effects of genotype and childhood adversity shape variability of DNA methylation across age
Czamara, D., Tissink, E., Tuhkanen, J., Martins, J., Awaloff, Y., Drake, A. J., Khulan, B., Palotie, A. V., Winter, S., Nemeroff, C. B., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-020-01147-z · Cited by 46 · see citing works
Self-citation
Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders
Ahmed, A. T., Frye, M. A., Rush, A. J., Biernacka, J. M., Craighead, W. E., McDonald, W. M., Bobo, W. V., Riva‐Posse, P., Tye, S. J., Mayberg, H. S., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.05.005 · Cited by 44 · see citing works
Self-citation
Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse
Kelley, M. E., Dunlop, B. W., Nemeroff, C. B., Lori, A., Carrillo‐Roa, T., Binder, E. B., Kutner, M., Aponte‐Rivera, V., Craighead, W. E., & Mayberg, H. S. (2018) · Depression and Anxiety · doi:10.1002/da.22832 · Cited by 44 · see citing works
Self-citation
Neuroanatomical dimensions in medication-free individuals with major depressive disorder and treatment response to SSRI antidepressant medications or placebo
Fu, C. H. Y., Antoniades, M., Erus, G., García, J., Yong Fan, A., Arnone, D., Arnott, S. R., Chen, T., Choi, K. S., Fatt, C. C., et al. (2024) · Nature Mental Health · doi:10.1038/s44220-023-00187-w · Cited by 37 · see citing works
Self-citation
BIOMARKER STUDIES AND THE FUTURE OF PERSONALIZED TREATMENT FOR DEPRESSION
Oquendo, M. A., McGrath, P. J., & Weissman, M. M. (2014) · Depression and Anxiety · doi:10.1002/da.22300 · Cited by 38 · see citing works
Neuroimaging for precision medicine in psychiatry
Williams, L. M., & Whitfield, S. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01917-z · Cited by 39 · see citing works
Somatic symptoms in treatment‐naïve Hispanic and non‐Hispanic patients with major depression
Dunlop, B. W., Still, S., LoParo, D., Aponte‐Rivera, V., Johnson, B. N., Schneider, R. L., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2019) · Depression and Anxiety · doi:10.1002/da.22984 · Cited by 39 · see citing works
Self-citation
Comprehensive phenotyping of depression disease trajectory and risk: Rationale and design of Texas Resilience Against Depression study (T-RAD)
Trivedi, M. H., Fatt, C. C., Jha, M. K., Cooper, C. M., Trombello, J. M., Mason, B. L., Hughes, J. L., Gadad, B. S., Czysz, A. H., Toll, R. T., et al. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.12.004 · Cited by 37 · see citing works
The Efficacy of Internal Family Systems Therapy in the Treatment of Depression Among Female College Students: A Pilot Study
Haddock, S. A., Weiler, L. M., Trump, L. J., & Henry, K. L. (2016) · Journal of Marital and Family Therapy · doi:10.1111/jmft.12184 · Cited by 36 · see citing works
Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests
Menke, A., Arloth, J., Best, J., Namendorf, C., Gerlach, T., Czamara, D., Lucae, S., Dunlop, B. W., Crowe, T. M., Garlow, S. J., et al. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.04.003 · Cited by 35 · see citing works
Self-citation
Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity
Carrillo‐Roa, T., Labermaier, C., Weber, P. C., Herzog, D. P., Lareau, C. A., Santarelli, S., Wagner, K. V., Rex‐Haffner, M., Harbich, D., Scharf, S. H., et al. (2017) · PLoS Biology · doi:10.1371/journal.pbio.2002690 · Cited by 35 · see citing works
Self-citation
ENHANCING HISPANIC PARTICIPATION IN MENTAL HEALTH CLINICAL RESEARCH: DEVELOPMENT OF A SPANISH-SPEAKING DEPRESSION RESEARCH SITE
Aponte‐Rivera, V., Dunlop, B. W., Ramirez, C. L., Kelley, M. E., Schneider, R. L., Blastos, B., Larson, J. C., Mercado, F., Mayberg, H. S., & Craighead, W. E. (2013) · Depression and Anxiety · doi:10.1002/da.22153 · Cited by 31 · see citing works
Self-citation
Model Specification and the Reliability of fMRI Results: Implications for Longitudinal Neuroimaging Studies in Psychiatry
Fournier, J. C. J., Chase, H. W., Almeida, J., & Phillips, M. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105169 · Cited by 31 · see citing works
Diagnostic classification of unipolar depression based on resting-state functional connectivity MRI: effects of generalization to a diverse sample
Sundermann, B., Feder, S. C., Wersching, H., Teuber, A., Schwindt, W., Kugel, H., Heindel, W. L., Arolt, V., Berger, K., & Pfleiderer, B. (2016) · Journal of Neural Transmission · doi:10.1007/s00702-016-1673-8 · Cited by 31 · see citing works
Treatment-Specific Hippocampal Subfield Volume Changes With Antidepressant Medication or Cognitive-Behavior Therapy in Treatment-Naive Depression
Tai, H.-H., Cha, J., Vedaei, F., Dunlop, B. W., Craighead, W. E., Mayberg, H. S., & Choi, K. S. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.718539 · Cited by 30 · see citing works
Self-citation
Pilot Study of Metabolomic Clusters as State Markers of Major Depression and Outcomes to CBT Treatment
Bhattacharyya, S., Dunlop, B. W., MahmoudianDehkordi, S., Ahmed, A. T., Louie, G., Frye, M. A., Weinshilboum, R. M., Krishnan, R. R., Rush, A. J., Mayberg, H. S., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00926 · Cited by 27 · see citing works
Self-citation
ERICH3: vesicular association and antidepressant treatment response
Liu, D., Zhuang, Y., Zhang, L., Gao, H., Neavin, D. R., Carrillo‐Roa, T., Wang, Y., Yu, J., Qin, S., Kim, D. C., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00940-y · Cited by 27 · see citing works
Self-citation
The Precision in Psychiatry (PIP) study: Testing an internet-based methodology for accelerating research in treatment prediction and personalisation
Lee, C. T., Palacios, J. E., Richards, D., Hanlon, A. K., Lynch, K., Harty, S., Claus, N., Swords, L., O’Keane, V., Stephan, K. E., et al. (2023) · BMC Psychiatry · doi:10.1186/s12888-022-04462-5 · Cited by 23 · see citing works
Behavioral activation for major depression in adolescents: Results from a pilot study.
Ritschel, L. A., Ramirez, C. L., Cooley, J. L., & Craighead, W. E. (2016) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12140 · Cited by 23 · see citing works
Self-citation
Prediction of treatment outcomes in major depressive disorder
Dunlop, B. W. (2015) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2015.1075390 · Cited by 22 · see citing works
Self-citation
Functional connectivity of salience and affective networks among remitted depressed patients predicts episode recurrence
Dunlop, B. W., Cha, J., Choi, K. S., Nemeroff, C. B., Craighead, W. E., & Mayberg, H. S. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01653-w · Cited by 22 · see citing works
Self-citation
Selective Serotonin Reuptake Inhibitor Pharmaco-Omics: Mechanisms and Prediction
Nguyen, T. T. L., Liu, D., Ho, M., Athreya, A. P., & Weinshilboum, R. M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.614048 · Cited by 24 · see citing works
AI-based dimensional neuroimaging system for characterizing heterogeneity in brain structure and function in major depressive disorder: COORDINATE-MDD consortium design and rationale
Fu, C. H. Y., Erus, G., Yong Fan, A., Antoniades, M., Arnone, D., Arnott, S. R., Chen, T., Choi, K. S., Fatt, C. C., Frey, B. N., et al. (2023) · BMC Psychiatry · doi:10.1186/s12888-022-04509-7 · Cited by 20 · see citing works
Self-citation
A depression network of functionally connected regions discovered via multi-attribute canonical correlation graphs
Kang, J., Bowman, F. D., Mayberg, H. S., & Liu, H. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.06.042 · Cited by 20 · see citing works
Self-citation
Differential change on depressive symptom factors with antidepressant medication and cognitive behavior therapy for major depressive disorder
Dunlop, B. W., Cole, S. P., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.12.035 · Cited by 20 · see citing works
Self-citation
Suicidal ideation and other persisting symptoms after CBT or antidepressant medication treatment for major depressive disorder
Dunlop, B. W., Polychroniou, P. E., Rakofsky, J. J., Nemeroff, C. B., Craighead, W. E., & Mayberg, H. S. (2018) · Psychological Medicine · doi:10.1017/s0033291718002568 · Cited by 20 · see citing works
Self-citation
Breakthroughs and challenges for generating brain network-based biomarkers of treatment response in depression
Prompiengchai, S., & Dunlop, K. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01907-1 · Cited by 22 · see citing works
A Bayesian Hierarchical Framework for Modeling Brain Connectivity for Neuroimaging Data
Chen, S., Bowman, F. D., & Mayberg, H. S. (2015) · Biometrics · doi:10.1111/biom.12433 · Cited by 19 · see citing works
Self-citation
Toll-like receptor 4 methylation grade is linked to depressive symptom severity
Rasmusson, A. J., Gallwitz, M., Soltanabadi, B., Ciuculete, D. M., Mengel‐From, J., Christensen, K., Nygaard, M., Soerensen, M., Boström, A. E. D., Fredriksson, R., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01481-w · Cited by 17 · see citing works
Self-citation
From Evidence to Practice: A Comprehensive Analysis of Side Effects in Synthetic Anti-Depressant Therapy
Pannu, A. S., & Goyal, R. K. (2024) · Current Drug Safety · doi:10.2174/0115748863301630240417071353 · Cited by 21 · see citing works
Recall accuracy for the symptoms of a major depressive episode among clinical trial participants
Dunlop, B. W., Granros, M., Lechner, A., Mletzko, T., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.03.008 · Cited by 16 · see citing works
Self-citation
Follow-up of monotherapy remitters in the PReDICT study: Maintenance treatment outcomes and clinical predictors of recurrence.
Kennedy, J. C., Dunlop, B. W., Craighead, L. W., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2018) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000279 · Cited by 18 · see citing works
Self-citation
Evaluating the Strength of Structural Connectivity Underlying Brain Functional Networks
Kemmer, P. B., Wang, Y., Bowman, F. D., Mayberg, H. S., & Guo, Y. (2018) · Brain Connectivity · doi:10.1089/brain.2018.0615 · Cited by 18 · see citing works
Self-citation
FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors
Schroeder, F. A., Chonde, D. B., Riley, M. M., Moseley, C. K., Granda, M. L., Wilson, C. M., Wagner, F. F., Zhang, Y., Gale, J. P., Holson, E. B., et al. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.06.016 · Cited by 15 · see citing works
Promising new pharmacological targets for depression: The search for efficacy
Tsugiyama, L. E., de Moraes, R. C. M., Moraes, Y. A. C., & de Oliveira, J. F. (2023) · Drug Discovery Today · doi:10.1016/j.drudis.2023.103804 · Cited by 14 · see citing works
Brain Circuit–Derived Biotypes for Treatment Selection in Mood Disorders: A Critical Review and Illustration of a Functional Neuroimaging Tool for Clinical Translation
Song, E. J., Tozzi, L., & Williams, L. M. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.03.016 · Cited by 15 · see citing works
Temporal Profiles and Dose-Responsiveness of Side Effects with Escitalopram and Duloxetine in Treatment-Naïve Depressed Adults
Polychroniou, P. E., Mayberg, H. S., Craighead, W. E., Rakofsky, J. J., Aponte‐Rivera, V., Haroon, E., & Dunlop, B. W. (2018) · Behavioral Sciences · doi:10.3390/bs8070064 · Cited by 13 · see citing works
Self-citation
Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms
Thomas, M., Coope, A., Falkenberg, C., Dunlop, B. W., Czamara, D., Provençal, N., Craighead, W. E., Mayberg, H. S., Nemeroff, C. B., Binder, E. B., et al. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.10.019 · Cited by 13 · see citing works
Self-citation
Multidimensional imaging techniques for prediction of treatment response in major depressive disorder
Langenecker, S. A., Klumpp, H., Peters, A. T., Crane, N. A., DelDonno, S. R., Bessette, K. L., Ajilore, O., Leow, A., Shankman, S. A., Walker, S. J., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.07.001 · Cited by 11 · see citing works
Prediction of individual patient outcomes to psychotherapy vs medication for major depression
LoParo, D., Dunlop, B. W., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2025) · npj Mental Health Research · doi:10.1038/s44184-025-00119-9 · Cited by 12 · see citing works
Self-citation
How well do clinicians and patients agree on depression treatment outcomes? Implications for personalized medicine
Dunlop, B. W., McCabe, B., Eudicone, J. M., Sheehan, J. J., & Baker, R. A. (2014) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.2428 · Cited by 12 · see citing works
Self-citation
Older Adults' Perspectives on Clinical Research: A Focus Group and Survey Study
Lenze, E. J., Ramsey, A. T., Brown, P. J., Reynolds, C. F., Mulsant, B. H., Lavretsky, H., & Roose, S. P. (2016) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.07.022 · Cited by 12 · see citing works
Getting Personalized: Brain Scan Biomarkers for Guiding Depression Interventions
Williams, L. M. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17030314 · Cited by 12 · see citing works
Assessing in-session rumination and its effects on CBT for depression
Kennedy, J. C., Dunlop, B. W., Craighead, L. W., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104209 · Cited by 11 · see citing works
Self-citation
Temporal multi-step predictive modeling of remission in major depressive disorder using early stage treatment data; STAR*D based machine learning approach
Salem, H., Huynh, T., Topolski, N., Mwangi, B., Trivedi, M. H., Soares, J. C., Rush, A. J., & Selvaraj, S. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.12.076 · Cited by 12 · see citing works
The Use of Psychotropic Medication in Pediatric Oncology for Acute Psychological and Psychiatric Problems: Balancing Risks and Benefits
Blom, J. M. C., Barisone, E., Bertolotti, M., Caprino, D., Cellini, M., Clerici, C. A., Colliva, C., Favara-Scacco, C., Giuseppe, S. D., Jankovic, M., et al. (2022) · Children · doi:10.3390/children9121878 · Cited by 11 · see citing works
Neuroimaging as a Tool for Individualized Treatment Choice in Depression: the Past, the Present and the Future
Godlewska, B. R. (2020) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-020-00198-2 · Cited by 15 · see citing works
Impact of Inflammation on White Matter Integrity and Functional Connectivity in Chronic Major Depressive Disorder
Cha, J., Raj, D., Choi, K. S., Rajendra, J. K., Nemeroff, C. B., Felger, J. C., Craighead, W. E., Mayberg, H. S., & Dunlop, B. W. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.06.026 · Cited by 9 · see citing works
Self-citation
Metabolomics signatures of serotonin reuptake inhibitor (escitalopram), serotonin norepinephrine reuptake inhibitor (duloxetine) and cognitive-behavioral therapy on key neurotransmitter pathways in major depressive disorder
Bhattacharyya, S., MahmoudianDehkordi, S., Sniatynski, M. J., Belenky, M., Marur, V. R., Rush, A. J., Craighead, W. E., Mayberg, H. S., Dunlop, B. W., Kristal, B. S., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.01.064 · Cited by 8 · see citing works
Self-citation
Developing Clinically Interpretable Neuroimaging Biotypes in Psychiatry
Ahn, J., Foland‐Ross, L. C., Akiki, T. J., Boyar, L., Wydler, I., Bostian, C. M., Zhang, X., Yang, H., Ellsay, A., Ma, E. W., et al. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2025.08.019 · Cited by 10 · see citing works
Co-alteration Network Architecture of Major Depressive Disorder: A Multi-modal Neuroimaging Assessment of Large-scale Disease Effects
Gray, J. P., Manuello, J., Alexander‐Bloch, A. F., Leonardo, C. D., Franklin, C. G., Choi, K. S., Cauda, F., Costa, T., Blangero, J., Glahn, D. C., et al. (2022) · Neuroinformatics · doi:10.1007/s12021-022-09614-2 · Cited by 8 · see citing works
Self-citation
Default Mode Network Hypoalignment of Function to Structure Correlates With Depression and Rumination
Thomas, P. J., Leow, A., Klumpp, H., Phan, K. L., & Ajilore, O. (2023) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2023.06.008 · Cited by 7 · see citing works
Graph theoretical measures of the uncinate fasciculus subnetwork as predictors and correlates of treatment response in a transdiagnostic psychiatric cohort
Thomas, P. J., Panchamukhi, S., Nathan, J., Francis, J., Langenecker, S. A., Gorka, S. M., Leow, A., Klumpp, H., Phan, K. L., & Ajilore, O. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111064 · Cited by 7 · see citing works
Development of a Bayesian multimodal model to detect biomarkers in neuroimaging studies
Bhaumik, D. K., Wang, Y., Yen, P., & Ajilore, O. (2023) · Frontiers in Neuroimaging · doi:10.3389/fnimg.2023.1147508 · Cited by 6 · see citing works
The utility of measuring daily hassles and uplifts in understanding outcomes to treatments for major depressive disorder
Furman, B. W., Craighead, W. E., Mayberg, H. S., Mletzko, T., Nemeroff, C. B., & Dunlop, B. W. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115859 · Cited by 5 · see citing works
Self-citation
Relationship between depressive disorders and personality traits: the value of the alternative five factor model
Ramos-Grille, I., Aragay, N., Valero, S., Garrido, G., Santacana, M., Guillamat, R., Vallès, V., & Gomà‐i‐Freixanet, M. (2020) · Current Psychology · doi:10.1007/s12144-020-01005-7 · Cited by 5 · see citing works
Biomarkers in Psychiatric Drug Development: From Precision Medicine to Novel Therapeutics
Carreon, R. L., Rivas-Grajales, A. M., Murphy, N., Mathew, S. J., & Jha, M. K. (2023) · Advances in neurobiology · doi:10.1007/978-3-031-21054-9_12 · Cited by 4 · see citing works
The Causes, Prevention and Treatment of Adolescent Depression: A Review
Li, J., Zhou, S., & Zhu, M. (2021) · Advances in Social Science, Education and Humanities Research/Advances in social science, education and humanities research · doi:10.2991/assehr.k.211220.009 · Cited by 4 · see citing works
The structure of personality disorders within a depressed sample: Implications for personalizing treatment
Berg, J. M., Kennedy, J. C., Dunlop, B. W., Ramirez, C. L., Stewart, L. M., Nemeroff, C. B., Mayberg, H. S., & Craighead, W. E. (2017) · Personalized Medicine in Psychiatry · doi:10.1016/j.pmip.2016.12.005 · Cited by 4 · see citing works
Self-citation
Brain Imaging and the Prediction of Treatment Outcomes in Mood and Anxiety Disorders
Leah, M., Klimes‐Dougan, B., & Kathryn, R. (2013) · InTech eBooks · doi:10.5772/55446 · Cited by 3 · see citing works
PSYCHOPHARMACOLOGY AND THE FUTURE OF PERSONALIZED TREATMENT
Nemeroff, C. B. (2014) · Depression and Anxiety · doi:10.1002/da.22303 · Cited by 4 · see citing works
Self-citation
Gut microbiome-linked metabolites in the pathobiology of depression and anxiety - a role for bile acidsPreprint
MahmoudianDehkordi, S., Bhattacharyya, S., Brydges, C. R., Jia, W. P., Fiehn, O., Rush, A. J., Dunlop, B. W., & Kaddurah-Daouk, R. F. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.04.485514 · Cited by 4 · see citing works
Self-citation

International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: Rationale and protocol
Williams, L. M., Rush, A. J., Koslow, S. H., Wisniewski, S. R., Cooper, N. J., Nemeroff, C. B., Schatzberg, A. F., & Gordon, E. (2011) · F1000Research · doi:10.7490/f1000research.1557.1
Self-citation
Brain imaging predictors and the international study to predict optimized treatment for depression: study protocol for a randomized controlled trial
Grieve, S. M., Korgaonkar, M. S., Etkin, A., Harris, A., Koslow, S. H., Wisniewski, S., Schatzberg, A. F., Nemeroff, C. B., Gordon, E., & Williams, L. M. (2013) · Trials · doi:10.1186/1745-6215-14-224 · Cited by 44 · see citing works
Self-citation
Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study
Dunlop, B. W., Kelley, M. E., Aponte‐Rivera, V., Mletzko, T., Kinkead, B. L., Ritchie, J., Nemeroff, C. B., Craighead, W. E., Mayberg, H. S., & for the PReDICT Team (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16050517 · Cited by 139 · see citing works
Self-citation
TRIALS STUDY PROTOCOL Open Access International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol
Williams, L. M., Rush, A. J., Koslow, S. H., Wisniewski, S. R., Cooper, N. J., Nemeroff, C. B., Schatzberg, A. F., & Gordon, E. (2013)
Self-citation
O-48 - The international study to predict optimized treatment - in depression: rational, design and initial findings
Rush, A. J., Williams, L. M., Koslow, S. H., Wisniewski, S. R., Cooper, N. J., Nemeroff, C. B., Schatzberg, A. F., & Gordon, E. (2012) · European Psychiatry · doi:10.1016/s0924-9338(12)74148-2
Self-citation

Authors: Dunlop, B. W., Binder, E. B., Cubells, J. F., Goodman, M. M., Kelley, M. E., Kinkead, B., Kutner, M., Nemeroff, C. B., Newport, D. J., Owens, M. J., Pace, T. W. W., Ritchie, J. C., Rivera, V. A., Westen, D., Craighead, W. E., & Mayberg, H. S.
Affiliations: Emory University (US)
University of Miami (US)
Corresponding author: Dunlop, Boadie W
ORCID: Dunlop, Boadie W
Binder, Elisabeth B
Cubells, Joseph F
Goodman, Mark M
Kelley, Mary E
Kinkead, Becky
Kutner, Michael
Nemeroff, Charles B
Newport, D Jeffrey
Pace, Thaddeus W W
Ritchie, James C
Craighead, W Edward
Mayberg, Helen S
Venue: Trials
Publisher: Springer Science and Business Media LLC
Published: 2012-07-09
Volume: 13
Issue: 1
Pages: 106-106
ISSN: 1745-6215 (ISSN-L)
DOI: 10.1186/1745-6215-13-106
PMC: PMC3539869
OpenAlex: W2140592967
Cited by: 136
References: 156
Citations by year: 2025: 8 · 2024: 10 · 2023: 15 · 2022: 12 · 2021: 9 · 2020: 18 · 2019: 12 · 2018: 10 · 2017: 8 · 2016: 9 · 2015: 5 · 2014: 7 · 2013: 10 · 2012: 2
FWCI: 5.60
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
www.springer.com/tdm (unspecified)
Locations: Trials (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
MPG.PuRe (Max Planck Society) (submittedVersion)
Funders: Eli Lilly and Company
National Institutes of Health (5r01mh080880-05, UL1TR000454, RR0039, MH077083, RR025008, MH080880, RO1 MH080880)
National Institute of Mental Health (K23MH086690, R01-MH080880, P50MH077083)
National Center for Research Resources (UL1RR025008, RR025008, M01RR000039)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: major depressive disorder, predictors of treatment response, remission, cognitive behavioral therapy, duloxetine, escitalopram, treatment-naive patients, treatment selection, personalized treatment, recurrence, dexamethasone/corticotropin-releasing hormone test, resting-state fMRI, immunological markers, gene expression, personality, combination therapy, antidepressant augmentation
MeSH terms: Duloxetine Hydrochloride, Adolescent, Adult, Aged, Antidepressive Agents, Brain, Major Depressive Disorder, Drug Therapy, Combination, Female, Genetic Testing, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Personality, Predictive Value of Tests, Remission Induction, Research Design, Thiophenes, Citalopram, Biomarkers, Treatment Outcome, Antidepressive Agents, Second-Generation, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks