Noradrenergic modulation of somatosensory cortical neuronal responses to lontophoretically applied putative neurotransmitters
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High levels of noradrenaline acting at α1- and β-receptors enhance memory consolidation processes in the hippocampus and increase the signal/noise ratio in primary sensory cortices.
“For example, high levels of noradrenaline acting at α1- and β-receptors enhance memory consolidation processes in the hippo-campus82,83 and increase the signal/noise ratio in primary sensory cortices84–86.”
From Stress signalling pathways that impair prefrontal cortex structure and function (2009) · cites this paper as [85]
In contrast to that in PFC, high levels of catecholamines strengthen the affective responses of the amygdala, the habitual or compulsive responses of the striatum and sensory processing in the primary somatosensory cortex.
“In contrast to that in PFC, high levels of catecholamines strengthen the affective responses of the amygdala22,64, the habitual or compulsive responses of the striatum65 and sensory processing in the primary somatosensory cortex66.”
From Stress weakens prefrontal networks: molecular insults to higher cognition (2015) · cites this paper as [66]
Local application of noradrenaline or stimulation of noradrenergic afferents in vivo enhances evoked responses.
“Local application of noradrenaline or stimulation of noradrenergic afferents in vivo reduces spontaneous firing194,195, but enhances evoked responses196–198”
From Mechanisms underlying gain modulation in the cortex (2020) · cites this paper as [197]
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Self-citation
- Authors
- Waterhouse, B. D., Moises, H. C., & Woodward, D. J.
- Affiliations
- University of Texas Health Science Center at Dallas (US)
- ORCID
- Waterhouse, Barry D.
- Venue
- Experimental Neurology
- Publisher
- Elsevier BV
- Published
- 1980-07
- Volume
- 69
- Issue
- 1
- Pages
- 30-49
- ISSN
- 0014-4886 (ISSN-L)
- OpenAlex
- W2015509669
- Cited by
- 209
- References
- 39
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 6 · 2017: 5 · 2016: 5 · 2015: 7 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- norepinephrine, noradrenergic modulation, somatosensory cortex, cortical neurons, acetylcholine, GABA, dopamine, iontophoresis, spontaneous firing rate, central noradrenergic system
- MeSH terms
- Acetylcholine, Action Potentials, Animals, Dopamine, Drug Antagonism, Drug Synergism, gamma-Aminobutyric Acid, Male, Neurons, Norepinephrine, Somatosensory Cortex, Rats
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