Patterns of cytochrome oxidase activity in the frontal agranular cortex of the macaque monkey
Abstract
The laminar pattern of cytochrome oxidase activity was studied in the agranular frontal cortex (area 4-6 complex) of the macaque monkey. The cortex, stained with this method, showed 6 stripes of different enzymatic activity. On the basis of their characteristics and of the presence of highly active cells, the agranular frontal cortex could be parcellated in 5 areas (F1-F5). F1 very likely corresponds to area FA of von Bonin and Bailey. Rostral to F1 two large regions could be distinguished, one located medial to the spur of the arcuate sulcus and its imaginary caudal extension, the other laterally. The superior region was formed by areas F2 and F3. The first was located on the dorsomedial cortical surface, the other on the mesial surface. F3 possibly corresponds to the supplementary motor area. The inferior region was formed by areas F4 and F5. The rostral area (F5) showed transition characteristics that rendered it somehow similar to the prefrontal areas. It may correspond to the cytoarchitectonic area FCBm. The cytocrome oxidase technique is a useful means of parcellating the agranular frontal cortex and may greatly help in physiological and behavioral experiments.
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From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Matelli et al. 1985
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From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Matelli et al. 1985
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From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Matelli et al. 1985
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“the dorsal caudal premotor cortex (PMDc or area F2 in the macaque monkey), which is involved in reaching movements”
From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Matelli et al. 1985
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“…integration; the dorsal rostral premotor cortex (PMDr or F7), responsible for learned responses to sensory stimuli; and the ventral rostral premotor cortex (PMVr or F5), specialized in grasping and hand-to-mouth movements (Matelli et al. 1985; Preuss et al. 1996; Rizzolatti et al. 1998).”
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- Authors
- Matelli, M., Luppino, G., & Rizzolatti, G.
- Affiliations
- University of Parma (IT)
- Corresponding author
- Matelli, Massimo
- ORCID
- Luppino, Giuseppe
- Venue
- Behavioural Brain Research
- Publisher
- Elsevier BV
- Published
- 1985-11
- Volume
- 18
- Issue
- 2
- Pages
- 125-136
- ISSN
- 0166-4328 (ISSN-L)
- OpenAlex
- W2055480316
- Cited by
- 519
- References
- 0
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 7 · 2023: 17 · 2022: 3 · 2021: 9 · 2020: 13 · 2019: 6 · 2018: 6 · 2017: 11 · 2016: 9 · 2015: 24 · 2014: 20 · 2013: 12 · 2012: 18
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioural Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centre National de la Recherche Scientifique
- National Institutes of Health (5r01ns019206-05)
- National Institute of Neurological Disorders and Stroke (1RO1 NS 19206-01A1)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- cytochrome oxidase activity, macaque, supplementary motor area, prefrontal cortex, cytoarchitectonic areas, arcuate sulcus
- MeSH terms
- Animals, Brain Mapping, Cerebral Cortex, Electron Transport Complex IV, Frontal Lobe, Histocytochemistry, Macaca nemestrina, Neurons
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