The DOI matches its Crossref record; 321 of the 325 references it cites were found in a registry or an index.
Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
Abstract
This review summarizes the current knowledge of characterized neurotrophic factors, including nerve growth factor (NGF) which serves as paradigmatic example when studying novel molecules. Special consideration is given to the function of neurotrophic factors in the adult and aging brain. Strategies are discussed for the eventual development of pharmacological applications of these molecules in the treatment of neurodegenerative diseases.
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“It is known that BDNF exerts positive effects such as anti-apoptosis, anti-inflammation, anti-neurotoxicity and neural regeneration.”
From Beneficial Effects of Spirulina Consumption on Brain Health (2022) · cites this paper as [99]
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Metadata
- Authors
- Hefti, F., Hartikka, J., & Knusel, B.
- Affiliations
- University of Southern California (US)
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 1989-09
- Volume
- 10
- Issue
- 5
- Pages
- 515-533
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2020771907
- Cited by
- 466
- References
- 325
- Citations by year
- 2024: 4 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 3 · 2012: 2
- FWCI
- 5.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurobiology of Aging (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (NS-22933)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Receptors and Signaling
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neurotrophic factors, nerve growth factor, brain aging, adult brain, neurodegenerative diseases, neurotrophic therapy, neuroprotection
- MeSH terms
- Aging, Alzheimer Disease, Animals, Humans, Nerve Growth Factors, Nervous System, Nervous System Physiological Phenomena, Parkinson Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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