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A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos

Rankin-Turner, Stephanie, Vader, Pieter, O'Driscoll, Lorraine, Giebel, Bernd, Heaney, Liam M., Davies, Owen G.·2021·Advanced Drug Delivery Reviews
DOI 10.1016/j.addr.2021.04.012PMC PMC8191593
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Graphical abstract CC BY · PubMed Central
Fig. 1 Summary of the variety of techniques utilised in loading studies for the isolation, quantification, loading and analysis of EVs.
Fig. 1 Summary of the variety of techniques utilised in loading studies for the isolation, quantification, loading and analysis of EVs.CC BY · PubMed Central
Fig. 2 The loading mechanism of therapeutic cargo into extracellular vesicles is dependent on the chemical characteristics of the molecule, with hydrophilic molecules entering the EV lumen and hydrophobic molecules accumulating in the lipid bilayer.
Fig. 2 The loading mechanism of therapeutic cargo into extracellular vesicles is dependent on the chemical characteristics of the molecule, with hydrophilic molecules entering the EV lumen and hydrophobic molecules accumulating in the lipid bilayer.CC BY · PubMed Central

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Metadata

Authors
Rankin-Turner, S., Vader, P., O'Driscoll, L., Giebel, B., Heaney, L. M., & Davies, O. G.
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2021-06
Volume
173
Pages
479-491
ISSN
0169-409X
DOI
10.1016/j.addr.2021.04.012
PMC
PMC8191593
Cited by
161
References
10
Language
en
Licence
Funders
  • European Research Council (851936)
  • Partnership for Clean Competition
  • Academy of Medical Sciences

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos. https://app.cochat.ai/papers/10.1016/j.addr.2021.04.012
The paper
Rankin-Turner, S., Vader, P., O'Driscoll, L., Giebel, B., Heaney, L. M., & Davies, O. G. (2021). A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2021.04.012