The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy

Griñán-Ferré, Christian, Bellver-Sanchis, Aina, Izquierdo, Vanessa, Corpas, Rubén, Roig-Soriano, Joan, Chillón, Miguel, Andres-Lacueva, Cristina, Somogyvári, Milán, Sőti, Csaba, Sanfeliu, Coral, Pallàs, Mercè·2021·Ageing Research Reviews

DOI 10.1016/j.arr.2021.101271

Cites (483)

Items 201–400 of 473

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease: from Mechanisms to Therapy
Shu-Hui Xin, Lin Tan, Xipeng Cao, Jin-Tai Yu, Lan Tan · 2018 · Neurotoxicity Research
Exercise-Induced Cognitive Plasticity, Implications for Mild Cognitive Impairment and Alzheimer’s Disease
Philip P. Foster, Kevin P. Rosenblatt, Rodrigo Orlando Kuljiš · 2011 · Frontiers in Neurology
Resveratrol Protects Rats from Aβ-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid Peroxidation
Tai-Chun Huang, Kwok‐Tung Lu, Yu-Yuan Peter Wo, Yao-Ju Wu, Yi-Ling Yang · 2011 · PLoS ONE
Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer’s disease
Hui Wang, Tianyue Jiang, Wěi Li, Na Gao, Tao Zhang · 2017 · Toxicology Letters
Roles of heat shock factor 1 beyond the heat shock response
János Barna, Péter Csermely, Tibor Vellai · 2018 · Cellular and Molecular Life Sciences
Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol
Morselli, Eugenia, Galluzzi, Lorenzo, Kepp, Oliver, Criollo, Alfredo, Maiuri, Maria Chiara, Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido · 2009 · Aging
Long-term consequences of maternal overweight in pregnancy on offspring later health: Findings from the Helsinki Birth Cohort Study
Eriksson, Johan G., Sandboge, Samuel, Salonen, Minna K., Kajantie, Eero, Osmond, Clive · 2014 · Annals of Medicine
Mitochondrial dysfunction, oxidative stress and neurodegeneration
Michelangelo Mancuso, Fabio Coppedè, Lucia Migliore, Gabriele Siciliano, Luigi Murri · 2006 · Journal of Alzheimer s Disease
Nutrition and the Risk of Alzheimer's Disease
Nan Hu, Jin‐Tai Yu, Lin Tan, Yingli Wang, Lei Sun, Lan Tan · 2013 · BioMed Research International
Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice
Strong, R., Miller, R. A., Astle, C. M., Baur, J. A., de Cabo, R., Fernandez, E., Guo, W., Javors, M., Kirkland, J. L., Nelson, J. F. et al. · 2013 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1)
Kohei Takeshita, Isao Suetake, Eiki Yamashita, Michihiro Suga, Hirotaka Narita, Atsushi Nakagawa, Shoji Tajima · 2011 · Proceedings of the National Academy of Sciences
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models
Ghazaleh Sadri‐Vakili, Bérengère Bouzou, Caroline Benn, Mee-Ohk Kim, Prianka Chawla, Ryan P. Overland, Kelly E. Glajch, Eva Xia, Zhihua Qiu, Steven M. Hersch et al. · 2007 · Human Molecular Genetics
Chromatin structure as a mediator of aging
Jason Feser, Jessica K. Tyler · 2010 · FEBS Letters
Histone methylation makes its mark on longevity
Han, Shuo, Brunet, Anne · 2012 · Trends in Cell Biology
Antioxidant Effects of Resveratrol in Cardiovascular, Cerebral and Metabolic Diseases
Carrizzo, Albino, Forte, Maurizio, Damato, Antonio, Trimarco, Valentina, Salzano, Francesco, Bartolo, Michelangelo, Maciag, Anna, Puca, Annibale A., Vecchione, Carmine · 2013 · Food and Chemical Toxicology
A cryptic Gondwana-forming orogen located in Antarctica
Nathan Robert Daczko, JA Halpin, I. C. W. Fitzsimons, Joanne M. Whittaker · 2018 · Scientific Reports
Roles of AMP-activated Protein Kinase in Alzheimer’s Disease
Zhiyou Cai, Liang‐Jun Yan, Keshen Li, Sohel H. Quazi, Bin Zhao · 2012 · NeuroMolecular Medicine
Epigenetics and Oxidative Stress in Aging
Amy Guillaumet-Adkins, Yania Yáñez, Manuel David Peris‐Díaz, Inés Calabria, Cora Palanca-Ballester, Juan Sandoval · 2017 · Oxidative Medicine and Cellular Longevity
Modulated microRNA expression during adult lifespan in Caenorhabditis elegans
Carolina Ibáñez‐Ventoso, Maocheng Yang, Suzhen Guo, Harlan S. Robins, Richard W. Padgett, Monica Driscoll · 2006 · Aging Cell
Chromatin remodeling in the aging genome of Drosophila
Wood, Jason G., Hillenmeyer, Sara, Lawrence, Charles, Chang, Chengyi, Hosier, Suzanne, Lightfoot, Will, Mukherjee, Eric, Jiang, Nan, Schorl, Christoph, Brodsky, Alexander S. et al. · 2010 · Aging Cell
Transgenerational epigenetic inheritance in mammals: How good is the evidence?
van Otterdijk, Sanne D., Michels, Karin B. · 2016 · The FASEB Journal
Resveratrol alleviates MPTP‐induced motor impairments and pathological changes by autophagic degradation of α‐synuclein via SIRT1‐deacetylated LC3
Yan‐Jie Guo, Su‐Yan Dong, Cui Xin-Xin, Ya Feng, Te Liu, Ming Yin, Sheng‐Han Kuo, Eng‐King Tan, Wen‐Juan Zhao, Yun‐Cheng Wu · 2016 · Molecular Nutrition & Food Research
Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction
Carlo Corona, Francesca Masciopinto, Elena Silvestri, Adelaide Del Viscovo, Rossano Lattanzio, Rossana La Sorda, Domenico Ciavardelli, Fernando Goglia, Mauro Piantelli, Lorella M.T. Canzoniero et al. · 2010 · Cell Death and Disease
Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
Xiaofeng Lu, Lili Ma, Lingfei Ruan, Yan Kong, Haiwei Mou, Zhijie Zhang, Zhijun Wang, Jiming Wang, Yingying Le · 2010 · Journal of Neuroinflammation
Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
Zhao Yong-na, Weifeng Li, Fei Yue Li, Zhen Zhang, Yun-Dong Dai, Ai-Li Xu, Qi Cui, Jimin Gao, Jun Gao · 2013 · Biochemical and Biophysical Research Communications
Age-related methylation of tumor suppressor and tumor-related genes: an analysis of autopsy samples
Takayoshi Waki, Gen Tamura, Makoto Sato, Teiichi Motoyama · 2003 · Oncogene
MicroRNAs in neurodegenerative diseases and their therapeutic potential
Junn, Eunsung, Mouradian, M. Maral · 2012 · Pharmacology & Therapeutics
Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats
Christopher C. Oakes, Dominic J. Smiraglia, Christoph Plass, Jacquetta M. Trasler, Bernard Robaire · 2003 · Proceedings of the National Academy of Sciences
The 5-Methylcytosine in DNA of Rats
B. F. Vanyushin, L E Nemirovskiĭ, V.V. Klimenko, V.K. Vasiliev, A. N. Belozersky · 2009 · Gerontologia
The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review.
F. Vahid, H. Zand, E. Nosrat–Mirshekarlou, R. Najafi, A. Hekmatdoost · 2015 · Gene
Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection
Mercè Pallàs, Gemma Casadesús, Mark A. Smith, Ana M. Coto‐Montes, Carme Pelegrı́, Jordi Vilaplana, Antoni Camins · 2009 · Current Neurovascular Research
Resveratrol and Alzheimer’s Disease: Mechanistic Insights
Touqeer Ahmed, Sehrish Javed, Sana Javed, Ameema Tariq, Dunja Šamec, Silvia Tejada, Seyed Fazel Nabavi, Nady Braidy, Seyed Mohammad Nabavi · 2016 · Molecular Neurobiology
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
Mark A. Casillas, Nadejda Lopatina, Lucy G. Andrews, Trygve O. Tollefsbol · 2003 · Molecular and Cellular Biochemistry
Reduction with age in methylcytosine in the promoter region −224∼−101 of the amyloid precursor protein gene in autopsy human cortex
Hideo Tohgi, Kimiaki Utsugisawa, Yuriko Nagane, Masahiro Yoshimura, Yasuko Genda, Miyuki Ukitsu · 1999 · Molecular Brain Research
Neuroprotective Role of Trans-Resveratrol in a Murine Model of Familial Alzheimer's Disease
David Porquet, Christian Griñán‐Ferré, Isidró Ferrer, Antoni Camins, Coral Sanfeliu, Jaume del Valle, Mercè Pallàs · 2014 · Journal of Alzheimer s Disease
NAD+ biosynthesis, aging, and disease
Johnson, Sean, Imai, Shin–ichiro · 2018 · F1000Research
Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration
Amrita Sahu, Hikaru Mamiya, Sunita N. Shinde, Amin Cheikhi, Leabah Winter, Nam Viet Vo, Donna Beer Stolz, Vera Y. Roginskaya, Wan‐Yee Tang, Claudette M. St. Croix et al. · 2018 · Nature Communications
Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly
Marília Baierle, Sabrina Nascimento, Angela Maria Moro, Natália Brucker, Fernando Freitas, Bruna Gauer, Juliano Durgante, Suelen Bordignon, Murilo Ricardo Zibetti, Clarissa M. Trentini et al. · 2015 · Oxidative Medicine and Cellular Longevity
Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation
Emma L. Wightman, Jonathon Lee Reay, Crystal F. Haskell‐Ramsay, Gary Williamson, Tristan P. Dew, David O. Kennedy · 2014 · British Journal Of Nutrition
Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells
Ryan E. Forster, Peter W. Jurutka, Jui‐Cheng Hsieh, Carol A. Haussler, Christine L. Lowmiller, Ichiro Kaneko, Mark R. Haussler, G. Kerr Whitfield · 2011 · Biochemical and Biophysical Research Communications
Effects of Resveratrol on Cognitive Performance, Mood and Cerebrovascular Function in Post-Menopausal Women; A 14-Week Randomised Placebo-Controlled Intervention Trial
Hamish M. Evans, Peter R.C. Howe, Rachel Heloise Xiwen Wong · 2017 · Nutrients
The case for transgenerational epigenetic inheritance in humans
Daniel K. Morgan, Emma Whitelaw · 2008 · Mammalian Genome
Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans
Jan Gruber, Soon Yew Tang, Barry B. Halliwell · 2007 · Annals of the New York Academy of Sciences
A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans
Diána Papp, Péter Csermely, Csaba Sőti · 2012 · PLoS Pathogens
Epigenetic Regulatory Mechanisms Induced by Resveratrol
Guilherme Fernandes, Gabriel Silva, Aline Renata Pavan, Diego Eidy Chiba, Chung Man Chin, Jean Leandro dos Santos · 2017 · Nutrients
Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Aβ1-42 oligomers and upregulating synaptic plasticity–related proteins in the hippocampus
Qinglin Li, Haifeng Zhao, Z.F. Zhang, Z.G. Liu, Xinrong Pei, J.B. Wang, Y. Li · 2009 · Neuroscience
CpG island chromatin
Neil P. Blackledge, Robert J. Klose · 2011 · Epigenetics
A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects
Joseph L. McClay, Karolina A. Åberg, Shaunna L. Clark, Srilaxmi Nerella, Gaurav Kumar, Lin Ying Xie, Alexandra D. Hudson, Aki Harada, Christina M. Hultman, Patrik K. E. Magnusson et al. · 2013 · Human Molecular Genetics
Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer’s Disease
Xianjuan Kou, Ning Chen · 2017 · Nutrients
Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement
Rubén Corpas, Christian Griñán‐Ferré, Eduard Rodrı́guez-Farré, Mercè Pallàs, Coral Sanfeliu · 2018 · Molecular Neurobiology
Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults
Wong, Rachel H.X., Berry, Narelle M., Coates, Alison M., Buckley, Jonathan D., Bryan, Janet, Kunz, Iris, Howe, Peter R.C. · 2013 · Journal of Hypertension
Synapse loss and progress of Alzheimer’s disease -A network model
G. Kashyap, Deepti Bapat, Debajyoti Das, Ruturaj Gowaikar, R. E. Amritkar, G. Rangarajan, Vijayalakshmi Ravindranath, G. Ambika · 2019 · Scientific Reports
Resveratrol Inhibits β-Amyloid-Induced Neuronal Apoptosis through Regulation of SIRT1-ROCK1 Signaling Pathway
Xiaowen Feng, Nan Liang, Dexiao Zhu, Qing Gao, Lei Peng, Haiman Dong, Qingwei Yue, Haili Liu, Lihua Bao, Jing Zhang et al. · 2013 · PLoS ONE
The Tor Pathway Regulates Gene Expression by Linking Nutrient Sensing to Histone Acetylation
John R. Rohde, Maria Elena Cardenas · 2002 · Molecular and Cellular Biology
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans
Masaomi Kato, Xiaowei Chen, Sachi Inukai, Hongyu Zhao, Frank John Slack · 2011 · RNA
Resveratrol reduces amyloid-beta (Aβ1–42)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans
Charlotte Regitz, Elena Fitzenberger, Friederike Luise Mahn, Lisa Marie Dußling, Uwe Wenzel · 2015 · European Journal of Nutrition
A Coordinate-Based Meta-Analysis of Overlaps in Regional Specialization and Functional Connectivity across Subjective Value and Default Mode Networks
M. Yavuz Acikalin, Krzysztof J. Gorgolewski, Russell Alan Poldrack · 2017 · Frontiers in Neuroscience
Neuroinflammation and anti-inflammatory therapy for Alzheimer’s disease
Amy H. Moore, M. Kerry O’Banion · 2002 · Advanced Drug Delivery Reviews
Searching for the role and the most suitable biomarkers of oxidative stress in Alzheimer's disease and in other neurodegenerative diseases
Lucia Migliore, I. Fontana, Renato Colognato, Fabio Coppedè, Gabriele Siciliano, Luigi Murri · 2004 · Neurobiology of Aging
Klotho protects against mouse renal fibrosis by inhibiting Wnt signaling
Minoru Satoh, Hajime Nagasu, Yoshitaka Morita, Terry P. Yamaguchi, Yashpal S. Kanwar, Naoki Kashihara · 2012 · American Journal of Physiology-Renal Physiology
Neuroprotective Effects of Resveratrol against Intracerebroventricular Colchicine-Induced Cognitive Impairment and Oxidative Stress in Rats
Anil Kumar, Pattipati S. Naidu, Neha Seghal, Satyanarayana S. V. Padi · 2006 · Pharmacology
Resveratrol as a Therapeutic Agent for Alzheimer’s Disease
Teng Ma, Meng‐Shan Tan, Jin‐Tai Yu, Lan Tan · 2014 · BioMed Research International
microRNA Control of Lifespan and Metabolism
Michelle Boehm, Frank John Slack · 2006 · Cell Cycle
Regulatory Roles of MicroRNAs in Diabetes
Juan Feng, Wanli Xing, Lan Xie · 2016 · International Journal of Molecular Sciences
Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro
Jun Shen, Linling Xu, Chujie Qu, Huimin Sun, Junjian Zhang · 2018 · Behavioural Brain Research
An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol
Ashim Malhotra, Sundeep Bath, Fawzy Elbarbry · 2015 · Oxidative Medicine and Cellular Longevity
Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats
Rita S. Strakovsky, Xiyuan Zhang, Dan Zhou, Yuan‐Xiang Pan · 2011 · The Journal of Physiology
The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer’s Disease
Shun‐Yao Ko, Hshin-An Ko, Kuo-Hsiung Chu, Tzong‐Ming Shieh, Tzong-Cherng Chi, Hong‐I Chen, Weng‐Cheng Chang, Shu-Shing Chang · 2015 · PLoS ONE
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease
Hanaa Hibishy Gaballah, Soha Said Zakaria, Maha M. ElBatsh, Nahid Tahoon · 2016 · Chemico-Biological Interactions
Neuroprotective effects of resveratrol against traumatic brain injury in immature rats
Ülker Sönmez, Ataç Sönmez, Güven Erbil, Işıl Tekmen, Başak Baykara · 2007 · Neuroscience Letters
The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model
Daniela Valenti, Lidia de BARI, Domenico De Rasmo, Anna Signorile, Alexandra Henrion‐Caude, Andrea Contestabile, Rosa Anna Vacca · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis
Shuting Zhang, Zhe Wang, Fang Cai, Mingming Zhang, Yili Wu, Jing Zhang, Weihong Song · 2017 · Journal of Neuroscience
Resveratrol‐based combinatorial strategies for cancer management
Chandra K. Singh, Jasmine George, Nihal Ahmad · 2013 · Annals of the New York Academy of Sciences
Overexpression of SIRT1 Protein in Neurons Protects against Experimental Autoimmune Encephalomyelitis through Activation of Multiple SIRT1 Targets
Vamshi K.C. Nimmagadda, Christopher T. Bever, Narasimha R. Vattikunta, Saifi Talat, Vakas Ahmad, Naveen K. Nagalla, David N. Trisler, Susan I. V. Judge, Walter Royal, Krish Chandrasekaran et al. · 2013 · The Journal of Immunology
Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the Clinical Evidence?
Gabriela Mazzanti, Silvia Di Giacomo · 2016 · Molecules
Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats
Haifeng Zhao, N. Li, Qiao-Ning Wang, Xuejiao Cheng, X.M. Li, T.T. Liu · 2015 · Neuroscience
Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging
Yoelvis García‐Mesa, Sandra Colié, Rubén Corpas, Rosa M. Cristòfol, Francesc Comellas, Ángel R. Nebreda, Lydia Giménez‐Llort, Coral Sanfeliu · 2015 · The Journals of Gerontology Series A
The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review
Kexin Wen, Jelena Milić, Bassem F. El‐Khodor, Klodian Dhana, Jana Nano, Tammy Pulido, Bledar Kraja, Asija Začiragić, Wichor Matthijs Bramer, John Troup et al. · 2016 · PLoS ONE
Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms
Robert G. Britton, Christina J. Kovoor, Karen Brown · 2015 · Annals of the New York Academy of Sciences
Resveratrol preserves cerebrovascular density and cognitive function in aging mice
Charlotte A. Oomen · 2009 · Frontiers in Aging Neuroscience
MicroRNA-214 participates in the neuroprotective effect of Resveratrol via inhibiting α-synuclein expression in MPTP-induced Parkinson’s disease mouse
Zhao-Hui Wang, Jian-Lei Zhang, Yan-Li Duan, Qishun Zhang, Guo-Fei Li, Dong-Lin Zheng · 2015 · Biomedicine & Pharmacotherapy
Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster
Amos Olalekan Abolaji, Adeola Oluwatosin Adedara, Mojisola A. Adie, Marta Vicente-Crespo, Ebenezer O. Farombi · 2018 · Biochemical and Biophysical Research Communications
Nutritional prevention of cognitive decline and dementia.
Ligia Juliana Dominguez, Mario Barbagallo · 2018 · Acta bio-medica dell'Ateneo parmense/Acta biomedica
Causes and Consequences of MicroRNA Dysregulation in Neurodegenerative Diseases
Lin Tan, Jin-Tai Yu, Lan Tan · 2014 · Molecular Neurobiology
The Role of Nutrition and Diet in Alzheimer Disease: A Systematic Review
Rusha Shah · 2013 · Journal of the American Medical Directors Association
Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span
Mintie Pu, Zhuoyu Ni, Minghui Wang, Xiujuan Wang, Jason G. Wood, Stephen L. Helfand, Haiyuan Yu, Siu Sylvia Lee · 2015 · Genes & Development
A randomized, double‐blind, placebo‐controlled trial of resveratrol with glucose and malate (RGM) to slow the progression of Alzheimer's disease: A pilot study
Carolyn Wei Zhu, Hillel T. Grossman, Judith A. Neugroschl, Susan Parker, Amanda R. Burden, Xiaodong Luo, Mary C. Sano · 2018 · Alzheimer s & Dementia Translational Research & Clinical Interventions
SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms
Rubén Corpas, Susana Revilla, Suzanna Ursulet, Marco Castro, Perla Kaliman, Valérie Petegnief, Lydia Giménez‐Llort, Chamsy Sarkis, Mercè Pallàs, Coral Sanfeliu · 2016 · Molecular Neurobiology
Current therapeutic targets for the treatment of Alzheimer’s disease
Joshua D. Grill, Jeffrey L. Cummings · 2010 · Expert Review of Neurotherapeutics
Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats
Bruna Bellaver, Débora Guerini de Souza, Diogo Onofre Souza, André Quincozes‐Santos · 2014 · Toxicology in Vitro
Resveratrol partially prevents oxidative stress and metabolic dysfunction in pregnant rats fed a low protein diet and their offspring
Claudia Cecilia Vega-García, Luis A. Reyes‐Castro, Guadalupe Leticia Rodríguez-González, Claudia Janet Bautista, Magaly Vázquez‐Martínez, Fernando Larrea, Germán A Chamorro‐Cevallos, Peter W. Nathanielsz, Elena Zambrano · 2015 · The Journal of Physiology
Mitochondrial Biology and Neurological Diseases
Siddharth Arun, Lei Liu, Gizem Dönmez · 2015 · Current Neuropharmacology
Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse
Yoelvis García‐Mesa, Lydia Giménez‐Llort, Luis Carlos López, Carmen Venegas, Rosa M. Cristòfol, Germaine Escames, Darío Acuña-Castroviejo, Coral Sanfeliu · 2011 · Neurobiology of Aging
The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease
Kundlik Gadhave, Nityanand B. Bolshette, Ashutosh Ahire, Rohit Pardeshi, Krishan Kumar Thakur, Cristiana-Maria Trandafir, Alexandru Istrate, Sahabuddin Ahmed, Mangala Lahkar, Dafin Fior Muresanu et al. · 2016 · Journal of Cellular and Molecular Medicine
Epigenetically regulated microRNAs in Alzheimer's disease
Daniël van den Hove, Konstantinos Kompotis, Roy Lardenoije, Günter Kenis, Jonathan S. Mill, Harry W.M. Steinbusch, Klaus‐Peter Lesch, Carlos Patricio Fitzsimons, Bart De Strooper, Bart P. F. Rutten · 2013 · Neurobiology of Aging
The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction
Brenda Rascón, Basil P. Hubbard, David A. Sinclair, Gro Vang Amdam · 2012 · Aging
Polyphenols in dementia: From molecular basis to clinical trials
Silvia Molino, Maurizia Dossena, Daniela Buonocore, Federica Ferrari, Letizia Venturini, Giovanni Ricevuti, Manuela Verri · 2016 · Life Sciences
The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster
Chunxu Wang, Charles T. Wheeler, Thomas Alberico, Xiaoping Sun, Jeanne Seeberger, Mara Laslo, Edward L. Spangler, Bradley Kern, Rafael de Cabo, Sige Zou · 2011 · AGE
Resveratrol Modulates SIRT1 and DNMT Functions and Restores LINE-1 Methylation Levels in ARPE-19 Cells under Oxidative Stress and Inflammation
Andrea Maugeri, Martina Barchitta, Maria Grazia Mazzone, Francesco Giuliano, Guido Basile, Antonella Agodi · 2018 · International Journal of Molecular Sciences
Sirt1 Promotes Axonogenesis by Deacetylation of Akt and Inactivation of GSK3
Xiaohong Li, Chong Chen, Yue Tu, Hongtao Sun, Mingliang Zhao, Shixiang Cheng, Yang Qu, Sai Zhang · 2013 · Molecular Neurobiology
Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer’s disease
Dolores Siedlecki‐Wullich, Judit Català-Solsona, Cristina Fábregas, Isabel Hernández, Jordi Clarimón, Alberto Lleó, Merçé Boada, Carlos A. Saura, José Rodrı́guez-Álvarez, Alfredo Jesús Miñano-Molina · 2019 · Alzheimer s Research & Therapy
Bioactive food compounds, epigenetics and chronic disease prevention: Focus on early-life interventions with polyphenols
Lívia Beatriz Aparecida Ribeiro Silva, Natália Castro, Gabriela Machado Novaes, Gabriela de Freitas Laiber Pascoal, Thomas Prates Ong · 2019 · Food Research International
Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction
Willy Barbot · 2002 · Nucleic Acids Research
Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans
Arnaud Tauffenberger, J. Alex Parker · 2014 · PLoS Genetics
Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases
Xi Chen, Jeff W. Barclay, Robert D. Burgoyne, Alan Morgan · 2015 · Chemistry Central Journal
Resveratrol promotes hUC-MSCs engraftment and neural repair in a mouse model of Alzheimer’s disease
Xinxin Wang, Shanshan Ma, Bo Yang, Tuanjie Huang, Nan Meng, Ling Xu, Qu Xing, Yan-ting Yann Zhang, Kun Zhang, Qinghua Li et al. · 2017 · Behavioural Brain Research
Should safety of the flu vaccine for cancer patients be reexamined?
Slobodan Paessler, Veljko Veljković · 2018 · F1000Research
Resveratrol Prevents CA1 Neurons against Ischemic Injury by Parallel Modulation of Both GSK-3β and CREB through PI3-K/Akt Pathways
Simão, Fabrício, Matté, Aline, Pagnussat, Aline S., Netto, Carlos A., Salbego, Christianne G. · 2012 · European Journal of Neuroscience
DIETARY FACTORS AND COGNITIVE DECLINE
Patrick J. Smith, James A. Blumenthal · 2015 · The Journal of Prevention of Alzheimer s Disease
Impact of Resveratrol on Glucose Control, Hippocampal Structure and Connectivity, and Memory Performance in Patients with Mild Cognitive Impairment
Theresa Köbe, A. Veronica Witte, Ariane Schnelle, Valentina Antonia Tesky, Johannes Pantel, Jan Philipp Schuchardt, Andreas Hahn, Jens Bohlken, Ulrike Grittner, Agnes Flöel · 2017 · Frontiers in Neuroscience
Resveratrol activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced inflammation and oxidative stress
Ming‐Chang Chiang, Christopher J.B. Nicol, Yi‐Chuan Cheng · 2017 · Neurochemistry International
The binding of resveratrol to monomer and fibril amyloid beta
Jin‐Fang Ge, Jinping Qiao, Congcong Qi, Chen-Wei Wang, Jiang‐Ning Zhou · 2012 · Neurochemistry International
Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease Patients
Marta Cosín‐Tomás, Júlia Senserrich, Marta Arumí-Planas, Carolina Alquézar, Mercè Pallàs, Ángeles Martín‐Requero, Cristina E. Sunol, Perla Kaliman, Coral Sanfeliu · 2019 · Nutrients
Aging in the Brain: New Roles of Epigenetics in Cognitive Decline
Jolie Barter, Thomas C. Foster · 2018 · The Neuroscientist
From Resveratrol to Its Derivatives: New Sources of Natural Antioxidant
Shan He, Xiaojun Yan · 2013 · Current Medicinal Chemistry
The effects of chronictrans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans
Emma L. Wightman, Crystal F. Haskell‐Ramsay, Jonathon Lee Reay, Gary Williamson, Tristan P. Dew, Wei Zhang, David O. Kennedy · 2015 · British Journal Of Nutrition
Neurons from senescence‐accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol
Rosa M. Cristòfol, David Porquet, Rubén Corpas, Ana M. Coto‐Montes, Jofre Serret, Antoni Camins, Mercè Pallàs, Coral Sanfeliu · 2011 · Journal of Pineal Research
Ageing‐Associated Oxidative Stress and Inflammation Are Alleviated by Products from Grapes
Kelly Shirley Petersen-Ross, Carine Smith · 2016 · Oxidative Medicine and Cellular Longevity
Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways
Kyoung Ja Kwon, Hee-Jin Kim, Chan Young Shin, Seol‐Heui Han · 2010 · Journal of Clinical Neurology
Tailoring of Proteostasis Networks with Heat Shock Factors
Jenny Joutsen, Lea Sistonen · 2018 · Cold Spring Harbor Perspectives in Biology
Dietary Modulation of the Epigenome
Folami Ideraabdullah, Steven H. Zeisel · 2018 · Physiological Reviews
Resveratrol Prevents the Development of Hypertension Programmed by Maternal Plus Post‐Weaning High‐Fructose Consumption through Modulation of Oxidative Stress, Nutrient‐Sensing Signals, and Gut Microbiota
You‐Lin Tain, Wei‐Chia Lee, Kay L. H. Wu, Steve Leu, Julie Y.H. Chan · 2018 · Molecular Nutrition & Food Research
Resveratrol Induces the Heat-Shock Response and Protects Human Cells from Severe Heat Stress
Ákos Putics, É. Végh, Péter Csermely, Csaba Sőti · 2007 · Antioxidants and Redox Signaling
Resveratrol reverses temozolomide resistance by downregulation of MGMT in T98G glioblastoma cells by the NF-κB-dependent pathway
Xiang Zhang · 2012 · Oncology Reports
The histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesis
Hongfeng Chen, Meiyun Fan, Lawrence M. Pfeffer, R. Nicholas Laribee · 2012 · Nucleic Acids Research
Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway
Shih-Che Hsu, Shih‐Ming Huang, Ann Chen, Chiao-Yin Sun, Shih‐Hua Lin, Jin‐Shuen Chen, Shuting Liu, Yu‐Juei Hsu · 2014 · The International Journal of Biochemistry & Cell Biology
Protective Effect of Resveratrol Against Oxidative Stress in Cholestasis
Cengiz Ara, Hale Kırımlıoğlu, Aysun Bay Karabulut, Sacit Çoban, Selma Ay, Murat M. M. Harputluoglu, Vedat Kırımlıoğlu, Sezai Yılmaz · 2005 · Journal of Surgical Research
DNA methylation in cancer development, diagnosis and therapy--multiple opportunities for genotoxic agents to act as methylome disruptors or remediators
J. Lewandowska, Agnieszka Bartoszek · 2011 · Mutagenesis
Low dose resveratrol improves cerebrovascular function in type 2 diabetes mellitus
Rachel Heloise Xiwen Wong, R.S. Nealon, Andrew B Scholey, Peter R.C. Howe · 2016 · Nutrition Metabolism and Cardiovascular Diseases
Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
Susann Schweiger, Frank Matthes, Karen L. Posey, Eva Kickstein, Stephanie S. Weber, Moritz M. Hettich, Sandra Pfurtscheller, Dan Ehninger, Rainer Schneider, Sybille Krauß · 2017 · Scientific Reports
Age-Related Increase in Levels of 5-Hydroxymethylcytosine in Mouse Hippocampus is Prevented by Caloric Restriction
Chouliaras, Leonidas, L.A. van den Hove, Daniel, Kenis, Gunter, Keitel, Stella, R. Hof, Patrick, van Os, Jim, W.M. Steinbusch, Harry, Schmitz, Christoph, P.F. Rutten, Bart · 2012 · Current Alzheimer Research
Identification of histone methylation multiplicities patterns in the brain of senescence-accelerated prone mouse 8
Chun Mei Wang, Sau Na Tsai, Tai Wai David Yew, Yiu Wa Kwan, Sai Ming Ngai · 2009 · Biogerontology
Influence of resveratrol on oxidative stress resistance and life span in Caenorhabditis elegans
Wei Chen, Leila Rezaizadehnajafi, Michaël Wink · 2013 · Journal of Pharmacy and Pharmacology
Antiaging Gene Klotho Attenuates Pancreatic β-Cell Apoptosis in Type 1 Diabetes
Yi Lin, Zhongjie Sun · 2015 · Diabetes
Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in β-amyloid-treated C6 glioma cells
Young Kim, Sun‐Young Lim, Sook‐Hee Rhee, Kun Park, Cheorl‐Ho Kim, Byung Choi, Su Jin Lee, Yeong‐Min Park, Yung Hyun Choi · 2006 · International Journal of Molecular Medicine
Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia.
Xingrong Ma, Zhikun Sun, Yanru Liu, Yanjie Jia, Boai Zhang, Jiewen Zhang · 2013 · PubMed Central
Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma
Caroline Ménard, Stéphane Bastianetto, Rémi Quirion · 2013 · Frontiers in Cellular Neuroscience
Administration of resveratrol improved Parkinson’s disease‐like phenotype by suppressing apoptosis of neurons via modulating the MALAT1/miR‐129/SNCA signaling pathway
Dongjian Xia, Rubo Sui, Zhuang Zhang · 2018 · Journal of Cellular Biochemistry
The Protective and Restorative Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Methadone-Induced Toxicity In Vitro
Erik Nylander, Sofia Zelleroth, Fred Nyberg, Alfhild Grönbladh, Mathias Hallberg · 2018 · International Journal of Molecular Sciences
Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells
Chin‐ok Yi, Byeong Tak Jeon, Hyun Joo Shin, Eun Ae Jeong, Ki Churl Chang, Jung Eun Lee, Dong Hoon Lee, Hyun Joon Kim, Sang Soo Kang, Gyeong Jae Cho et al. · 2011 · Anatomy & Cell Biology
Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
Christian Griñán‐Ferré, Rubén Corpas, Dolors Puigoriol‐Illamola, Verónica Palomera‐Ávalos, Coral Sanfeliu, Mercè Pallàs · 2018 · Journal of Alzheimer s Disease
Klotho suppresses the inflammatory responses and ameliorates cardiac dysfunction in aging endotoxemic mice
Haipeng Hui, Yufeng Zhai, Lihua Ao, Joseph C. Cleveland, Hongbin Liu, David A. Fullerton, Xianzhong Meng · 2017 · Oncotarget
Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype
Natalie E. Simpson, Volodymyr Tryndyak, Marta Pogribna, Frederick A. Beland, Igor P. Pogribny · 2012 · Epigenetics
Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice
So-Young Han, Jong-Ryoul Choi, Ki Soon Shin, Shin Jung Kang · 2012 · Brain Research
Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice
Sueli Marques, Raquel Lemos, Elisabete B. Ferreiro, Madalena Martins, Alexandre de Mendonça, Isabel J. Santana, Tiago F. Outeiro, Cláudia Pereira · 2012 · Neuroscience
Epigenetics and neurodegeneration: role of early-life nutrition
Rosita Gabbianelli, Elisabetta Damiani · 2018 · The Journal of Nutritional Biochemistry
Properties and molecular mechanisms of resveratrol: a review
Tingting Yang, Lı Wang, Meixiao Zhu, Lirong Zhang, Lianhe Yan · 2015 · Die Pharmazie
Epigenetic mechanisms related to cognitive decline during aging
María Florencia Harman, Mauricio G. Martín · 2019 · Journal of Neuroscience Research
Resveratrol Attenuates Oxidative Damage and Ameliorates Cognitive Impairment in the Brain of Senescence-Accelerated Mice
Liu, Gui-Shan, Zhang, Ze-Sheng, Yang, Bo, He, Wei · 2012 · Life Sciences
Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study
Fabio Ciccarone, Marco Malavolta, Roberta Calabrese, Tiziana Guastafierro, Maria Giulia Bacalini, Anna Reale, Claudio Franceschi, Miriam Capri, Antti Hervonen, Mikko Hurme et al. · 2016 · Aging Cell
Oxidative stress mediated by NMDA, AMPA/KA channels in acute hippocampal slices: Neuroprotective effect of resveratrol
André Quincozes‐Santos, Larissa Daniele Bobermin, Ana Carolina Tramontina, Krista Minéia Wartchow, Bárbara Tagliari, Diogo Onofre Souza, Ângela Terezinha de Souza Wyse, Carlos‐Alberto Gonçalves · 2014 · Toxicology in Vitro
β-secretase (BACE1)-inhibiting stilbenoids from Smilax Rhizoma
So Young Jeon, Soon-Ho Kwon, Yeon Hee Seong, K. Bae, J.-M. Hur, Y.-Y. Lee, Dae‐Yeon Suh, Kyung Sik Song · 2006 · Phytomedicine
Recent Findings in Alzheimer Disease and Nutrition Focusing on Epigenetics
Dimitrios Athanasopoulos, George Karagiannis, Magda Tsolaki · 2016 · Advances in Nutrition
Caenorhabditis elegans: A Useful Model for Studying Metabolic Disorders in Which Oxidative Stress Is a Contributing Factor
Elizabeth Moreno-Arriola, Noemí Cárdenas‐Rodríguez, Elvia Coballase-Urrutía, José Pedraza‐Chaverrí, Liliana Carmona‐Aparicio, Daniel Ortega-Cuéllar · 2014 · Oxidative Medicine and Cellular Longevity
Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development
Dagmar E. Ehrnhoefer, Bibiana K. Y. Wong, Michael R. Hayden · 2011 · Nature Reviews Drug Discovery
Effects of resveratrol on longevity, cognitive ability and aging-related histological markers in the annual fish Nothobranchius guentheri
Xin Yu, Guorong Li · 2012 · Experimental Gerontology
Histone Modifications in Aging: The Underlying Mechanisms and Implications
Yuan Wang, Quan Yuan, Liang Xie · 2018 · Current Stem Cell Research & Therapy
Resveratrol decreases the expression of genes involved in inflammation through transcriptional regulation
Daniele Maria Lopes Pinheiro, Ana Helena Sales de Oliveira, Leonam Gomes Coutinho, Fabrícia Lima Fontes-Dantas, Rayssa Karla de Medeiros Oliveira, Thais Teixeira Oliveira, André Luís Fonseca Faustino, Vandeclécio Lira da Silva, Julliane Tamara Araújo de Melo Campos, Tirzah Braz Petta Lajus et al. · 2018 · Free Radical Biology and Medicine
TET Family of Dioxygenases: Crucial Roles and Underlying Mechanisms
Duo Li, Bin Guo, Haijing Wu, Lina Tan, Qianjin Lu · 2015 · Cytogenetic and Genome Research
Resveratrol Acts Not through Anti-Aggregative Pathways but Mainly via Its Scavenging Properties against Aβ and Aβ-Metal Complexes Toxicity
Alberto Granzotto, Paolo F. Zatta · 2011 · PLoS ONE
MicroRNA genetic variations: association with type 2 diabetes
Cinzia Ciccacci, Davide Di Fusco, Laura Cacciotti, Roberto Morganti, Cinzia D’Amato, Carla Greco, Sara Rufini, Giuseppe Novelli, Federica Carla Sangiuolo, Vincenza Spallone et al. · 2013 · Acta Diabetologica
Effect of resveratrol supplementation on cognitive performance and mood in adults: a systematic literature review and meta-analysis of randomized controlled trials
Wolfgang Marx, Jaimon Terence Kelly, Skye Marshall, Jennifer Cutajar, Brigitte Annois, Andrew Pipingas, Audrey C. Tierney, Catherine Itsiopoulos · 2018 · Nutrition Reviews
Antiaging Gene Klotho Enhances Glucose-Induced Insulin Secretion by Up-Regulating Plasma Membrane Levels of TRPV2 in MIN6 β-Cells
Yi Lin, Zhongjie Sun · 2012 · Endocrinology
Effects of Resveratrol and Other Polyphenols on the Most Common Brain Age-Related Diseases
Fiorella Sarubbo, David Moranta, Víctor J. Asensio, Antonio Miralles, Susana Esteban · 2017 · Current Medicinal Chemistry
Effects of resveratrol on bone health in type 2 diabetic patients. A double-blind randomized-controlled trial
Simona Bo, Roberto Gambino, Valentina Ponzo, Iolanda Cioffi, Ilaria Goitre, Andrea Evangelista, Giovannino Ciccone, Maurizio Cassader, Procopio Massimo · 2018 · Nutrition and Diabetes
From Resveratrol to Its Derivatives: New Sources of Natural Antioxidant
Shan He, Xiaojun Yan · 2013 · Current Medicinal Chemistry
Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons
Sachin P. Patil, Nhung T. Tran, Hirosha Geekiyanage, Li Liu, Christina Chan · 2013 · Neuroscience Letters
Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer’s disease
Caterina Scuderi, Claudia Stecca, Maria Rosanna Bronzuoli, Dante Rotili, Sérgio Valente, Antonello Mai, Luca Steardo · 2014 · Frontiers in Pharmacology
Resveratrol Protects β Amyloid-Induced Oxidative Damage and Memory Associated Proteins in H19-7 Hippocampal Neuronal Cells
Shraddha D. Rege, Thangiah Geetha, Tom L. Broderick, Jeganathan Ramesh Babu · 2015 · Current Alzheimer Research
Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol
Chien‐Ning Hsu, Yu‐Ju Lin, You‐Lin Tain · 2019 · International Journal of Molecular Sciences
Disruption of neocortical histone H3 homeostasis by soluble Aβ: implications for Alzheimer's disease
Christina Unger Lithner, Pascale N. Lacor, Wei-Qin Zhao, Tamanna Mustafiz, William L. Klein, J. David Sweatt, Caterina M. Hernandez · 2013 · Neurobiology of Aging
Mechanisms of Age-Related Cognitive Change and Targets for Intervention: Epigenetics
Kenneth S. Kosik, Peter R. Rapp, Naftali Raz, Scott A. Small, J. David Sweatt, Li‐Huei Tsai · 2012 · The Journals of Gerontology Series A
Advanced glycation end products and lipopolysaccharides stimulate interleukin‑6 secretion via the RAGE/TLR4‑NF‑κB‑ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages
Ayaka Ohtsu, Yui Shibutani, Kotomi Seno, Hisataka Iwata, Takehito Kuwayama, Koumei Shirasuna · 2017 · Experimental and Therapeutic Medicine
Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy
Zhihao Wu, Alan Wu, Jason Dong, Andy Sigears, Bingwei Lu · 2018 · Experimental Gerontology
Resveratrol attenuates lipopolysaccharide-induced hepatitis in d-galactosamine sensitized rats: Role of nitric oxide synthase 2 and heme oxygenase-1
Hassan Farghali, Dalibor Černý, LUDMILA KAMENÍKOVÁ, J Martínek, Aleš Hořínek, Eva Kmonı́čková, Zdeňek Zı́dek · 2009 · Nitric Oxide
The effect of resveratrol on longevity across species: a meta-analysis
Katie L. Hector, Malgorzata Lagisz, Shinichi Nakagawa · 2012 · Biology Letters
Resveratrol protects against L-arginine-induced acute necrotizing pancreatitis in mice by enhancing SIRT1-mediated deacetylation of p53 and heat shock factor 1
Nian Wang, Fen Zhang, Liu Yang, Jiang Zou, Hao Wang, Ke Liu, Meidong Liu, Huali Zhang, Xianzhong Xiao, Kangkai Wang · 2017 · International Journal of Molecular Medicine
Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system
Mao‐Meng Tiao, Yu‐Ju Lin, Hong‐Ren Yu, Jiunn‐Ming Sheen, I-Chun Lin, Yun‐Ju Lai, You‐Lin Tain, Li‐Tung Huang, Ching‐Chou Tsai · 2018 · Lipids in Health and Disease
All-trans retinoic acid induces COX-2 and prostaglandin E2 synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2
Matilde Alique, Juan F. Herrero, Francisco Javier Lucio-Cazaña · 2007 · Journal of Neuroinflammation
Metabolic Stress Induces Cognitive Disturbances and Inflammation in Aged Mice: Protective Role of Resveratrol
Verónica Palomera‐Ávalos, Christian Griñán‐Ferré, Vanesa Izquierdo, Antoni Camins, Coral Sanfeliu, Mercè Pallàs · 2016 · Rejuvenation Research
Neuroprotective Effect of Smilacis chinae Rhizome on NMDA-Induced Neurotoxicity In Vitro and Focal Cerebral Ischemia In Vivo
Ju Yeon Ban, Soon Ock Cho, Sun Ha Choi, HYUN JU CHA, Ju Yeon Kim, KiHwan Bae, Kyung‐Sik Song, Yeon Hee Seong · 2008 · Journal of Pharmacological Sciences
The Influence of Dietary Factors in Central Nervous System Plasticity and Injury Recovery
Fernando Gómez‐Pinilla, Alexis G. Gomez · 2011 · PM&R
Effect of Resveratrol on Reactive Oxygen Species-Induced Cognitive Impairment in Rats with Angiotensin II-Induced Early Alzheimer’s Disease †
Yu‐Te Lin, Yi‐Chung Wu, Gwo‐Ching Sun, Chiu‐Yi Ho, Tzyy‐Yue Wong, Ching‐Huang Lin, Hsin‐Hung Chen, Tung‐Chen Yeh, Chia‐Jung Li, Ching‐Jiunn Tseng et al. · 2018 · Journal of Clinical Medicine
Resveratrol (3, 5, 4′-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain
K. Alexa Orr Gandy, Jiajia Zhang, Prakash S. Nagarkatti, Mitzi Nagarkatti · 2019 · Journal of Neuroimmune Pharmacology
After the grape rush: Sirtuins as epigenetic drug targets in neurodegenerative disorders
K. Huber, Giulio Superti‐Furga · 2011 · Bioorganic & Medicinal Chemistry
Resveratrol and Red Wine Function as Antioxidants in the Nervous System without Cellular Proliferative Effects during Experimental Diabetes
Carina Duarte Venturini, Suélen Merlo, André Arigony Souto, Marilda da Cruz Fernandes, Rosane Gomez, Cláudia Ramos Rhoden · 2010 · Oxidative Medicine and Cellular Longevity
Effect of Oral Resveratrol on the BDNF Gene Expression in the Hippocampus of the Rat Brain
Mostafa Rahvar, Mohsen Nikseresht, Sayed Mohammad Shafiee, Fakhraddin Naghibalhossaini, Mozhgan Rasti, Mohammad Reza Panjehshahin, Ali Akbar Owji · 2011 · Neurochemical Research
Resveratrol Stimulates Mitochondrial Bioenergetics to Protect Retinal Pigment Epithelial Cells From Oxidative Damage
Shwu‐Jiuan Sheu, Ni-Chun Liu, Chen-Chun Ou, Youn‐Shen Bee, Shih-Chou Chen, Hsiu-Chen Lin, Julie Y.H. Chan · 2013 · Investigative Ophthalmology & Visual Science
Dietary methyl donor deficiency during pregnancy in rats shapes learning and anxiety in offspring
Galina Konycheva, Marie A. Dziadek, Lynnette Robyn Ferguson, Christian U. Krägeloh, Marcel W. Coolen, Michael Davison, Bernhard H. Breier · 2011 · Nutrition Research
Use of Caenorhabditis elegans To Study the Potential Bioactivity of Natural Compounds
Vivian Hsiu‐Chuan Liao · 2018 · Journal of Agricultural and Food Chemistry
Combined maternal and postnatal high-fat diet leads to metabolic syndrome and is effectively reversed by resveratrol: a multiple-organ study
Jiunn‐Ming Sheen, Hong‐Ren Yu, You‐Lin Tain, Wan-Long Tsai, Mao‐Meng Tiao, I-Chun Lin, Ching‐Chou Tsai, Yu‐Ju Lin, Li‐Tung Huang · 2018 · Scientific Reports
Resveratrol and Alzheimer's disease. From molecular pathophysiology to clinical trials
Krzysztof Drygalski, Eliza Fereniec, Krzysztof Koryciński, Andrzej Chomentowski, Aleksandra Kiełczewska, Cezary Odrzygóźdź, Beata Modzelewska · 2018 · Experimental Gerontology
Optical and SPION-Enhanced MR Imaging Shows that trans-Stilbene Inhibitors of NF-κB Concomitantly Lower Alzheimer's Disease Plaque Formation and Microglial Activation in AβPP/PS-1 Transgenic Mouse Brain
Nathan O. Solberg, Ryan Chamberlin, Jenette R. Vigil, Lorraine M. Deck, John E. Heidrich, David C. Brown, Christina I. Brady, Thomas A. Vander Jagt, Michael Garwood, Marco Bisoffi et al. · 2014 · Journal of Alzheimer s Disease
Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells
Xiang Zhang · 2011 · Oncology Reports
Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model
Huagang Li, Jing Wang, Pu Wang, Yan Rao, Liping Chen · 2015 · Journal of Stroke and Cerebrovascular Diseases
Resveratrol Inhibits Oligomeric Aβ-Induced Microglial Activation via NADPH Oxidase
YAO, YAO, LI, JUAN, NIU, YANG, YU, JIAN-QIANG, YAN, LING, MIAO, ZHEN-HUA, ZHAO, XUN-XIA, LI, YUAN-JIE, YAO, WAN-XIA, ZHENG, PING et al. · 2015 · Molecular Medicine Reports
Drug Metabolism and Oxidative Stress: Cellular Mechanism and New Therapeutic Insights
Sharmistha Banerjee, Jyotirmoy Ghosh · 2016 · Biochemistry & Analytical Biochemistry
Hippocampal TET1 and TET2 Expression and DNA Hydroxymethylation Are Affected by Physical Exercise in Aged Mice
Peter Jessop, Maria Toledo‐Rodriguez · 2018 · Frontiers in Cell and Developmental Biology
1,25-Dihydroxyvitamin D and Klotho
Mark R. Haussler, G. Kerr Whitfield, Carol A. Haussler, Marya S. Sabir, Zainab Khan, Ruby Sandoval, Peter W. Jurutka · 2016 · Vitamins and hormones
Maternal Resveratrol Supplementation Prevents Cognitive Decline in Senescent Mice Offspring
Vanesa Izquierdo, Verónica Palomera‐Ávalos, Sergio López-Ruiz, Anna-Maria Canudas, Mercè Pallàs, Christian Griñán‐Ferré · 2019 · International Journal of Molecular Sciences