Peroxisomal ABC transporters: Structure, function and role in disease

ABC Transporters: From Microorganisms to Man

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Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

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Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

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Structure of a bacterial multidrug ABC transporter

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Presenting your structures: theCCP4mgmolecular-graphics software

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Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

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Biochemistry of mammalian peroxisomes revisited

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Human ATP-binding cassette (ABC) transporter family

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Flexibility in the ABC transporter MsbA: Alternating access with a twist

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The Arabidopsis thaliana ABC Protein Superfamily, a Complete Inventory

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Cholesterol metabolism in neurons and astrocytes

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The ABC of ABCs: a phylogenetic and functional classification of ABC systems in living organisms

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Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy

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The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

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The Arabidopsis pxa1 Mutant Is Defective in an ATP-Binding Cassette Transporter-Like Protein Required for Peroxisomal Fatty Acid beta -Oxidation

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Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

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The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER

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Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism

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Adrenoleukodystrophy: Incidence, new mutation rate, and results of extended family screening

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Getting In or Out: Early Segregation Between Importers and Exporters in the Evolution of ATP-Binding Cassette (ABC) Transporters

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The ABC transporter proteins Pat1 and Pat2 are required for import of long‐chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

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Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP

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Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis

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Jasmonic Acid Levels Are Reduced in COMATOSE ATP-Binding Cassette Transporter Mutants. Implications for Transport of Jasmonate Precursors into Peroxisomes

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Adrenoleukodystrophy: Incidence, new mutation rate, and results of extended family screening

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The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl–CoA esters

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Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome

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A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

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Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

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Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy

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Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.

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Glial Lipoproteins Stimulate Axon Growth of Central Nervous System Neurons in Compartmented Cultures

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Ped3p is a Peroxisomal ATP-Binding Cassette Transporter that might Supply Substrates for Fatty Acid β-Oxidation

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Peroxisome assembly: matrix and membrane protein biogenesis

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Toxic effects of X-linked adrenoleukodystrophy-associated, very long chain fatty acids on glial cells and neurons from rat hippocampus in culture

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Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?

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Peroxisomal Membrane Proteins Contain Common Pex19p-binding Sites that Are an Integral Part of Their Targeting Signals

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The ABC Transporter PXA1 and Peroxisomal β-Oxidation Are Vital for Metabolism in Mature Leaves of Arabidopsis during Extended Darkness

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The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy

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Metabolite transport across the peroxisomal membrane

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Peroxisomal Membrane Proteins Insert into the Endoplasmic Reticulum

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The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway

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Adrenoleukodystrophy-Related Protein Can Compensate Functionally for Adrenoleukodystrophy Protein Deficiency (X-ALD): Implications for Therapy

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Import of peroxisomal membrane proteins: The interplay of Pex3p- and Pex19p-mediated interactions

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Homo- and Heterodimerization of Peroxisomal ATP-binding Cassette Half-transporters

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Antioxidants halt axonal degeneration in a mouse model of X‐adrenoleukodystrophy

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Protein import machineries of peroxisomes

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Adreno-leukodystrophy: Oxidative Stress of Mice and Men

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Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation

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Potential Environmental and Host Participants in the Early White Matter Lesion of Adreno-Leukodystrophy: Morphologic Evidence for CD8 Cytotoxic T Cells, Cytolysis of Oligodendrocytes, and CD1-Mediated Lipid Antigen Presentation

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Identification of a Fourth Half ABC Transporter in the Human Peroxisomal Membrane

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Be different—The diversity of peroxisomes in the animal kingdom

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Peroxisomal ABC transporters

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Transport of Activated Fatty Acids by the Peroxisomal ATP‐binding‐cassette Transporter Pxa2 in a Semi‐Intact Yeast Cell System

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Biochemical aspects of X-linked adrenoleukodystrophy

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Mammalian peroxisomal ABC transporters: from endogenous substrates to pathology and clinical significance

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Plasmalogens participate in very-long-chain fatty acid-induced pathology

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Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients

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Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts.

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A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis

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Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy

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Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins

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Characterization of the 70-kDa Peroxisomal Membrane Protein, an ATP Binding Cassette Transporter

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cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter

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Primary Structure of Human PMP69, a Putative Peroxisomal ABC-Transporter

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Head trauma can initiate the onset of adreno-leukodystrophy

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Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy

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Oxidative Damage Compromises Energy Metabolism in the Axonal Degeneration Mouse Model of X-Adrenoleukodystrophy

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Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis

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Mirror expression of adrenoleukodystrophy and adrenoleukodystrophy related genes in mouse tissues and human cell lines

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Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin

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Domain Architecture and Activity of Human Pex19p, a Chaperone-like Protein for Intracellular Trafficking of Peroxisomal Membrane Proteins

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Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters

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Function of the PEX19-binding Site of Human Adrenoleukodystrophy Protein as Targeting Motif in Man and Yeast

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Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes

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Astrocyte phenotypes and their relationship to myelination

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Evolutionary Analyses of ABC Transporters of Dictyostelium discoideum

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The Arabidopsis Peroxisomal ABC Transporter, Comatose, Complements the Saccharomyces cerevisiae pxa1 pxa2Δ Mutant for Metabolism of Long-chain Fatty Acids and Exhibits Fatty Acyl-CoA-stimulated ATPase Activity

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Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy

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Peroxisomes, myelination, and axonal integrity in the CNS

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ATP Binding/Hydrolysis by and Phosphorylation of Peroxisomal ATP-binding Cassette Proteins PMP70 (ABCD3) and Adrenoleukodystrophy Protein (ABCD1)

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Oligodendroglial impact on axonal function and survival – a hypothesis

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Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p

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70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins

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Mouse liver PMP70 and ALDP: homomeric interactions prevail in vivo

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Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19*

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