Plasmalogens participate in very-long-chain fatty acid-induced pathology

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129 · see citing works

Biochemistry of mammalian peroxisomes revisited

Wanders, R. J. A., & Waterham, H. R. (2006) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133329 · Cited by 995 · see citing works

X-linked adrenoleukodystrophy

Moser, H. W., Mahmood, A., & Raymond, G. V. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0421 · Cited by 663 · see citing works

Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy

Moser, H. (1997) · Brain · doi:10.1093/brain/120.8.1485 · Cited by 478 · see citing works

Functions and biosynthesis of plasmalogens in health and disease

Brites, P., Waterham, H. R., & Wanders, R. J. A. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2003.12.010 · Cited by 415 · see citing works

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

Kassmann, C. M., Lappe-Siefke, C., Baes, M., Brügger, B., Mildner, A., Werner, H. B., Natt, O., Michaelis, T., Prinz, M., Frahm, J., et al. (2007) · Nature Genetics · doi:10.1038/ng2070 · Cited by 357 · see citing works

A mouse model for X-linked adrenoleukodystrophy

Lu, J.-F., Lawler, A. M., Watkins, P. A., Powers, J. M., Moser, A. B., Moser, H. W., & Smith, K. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.9366 · Cited by 293 · see citing works

A mouse model for Zellweger syndrome

Baes, M., Gressens, P., Baumgart, E., Carmeliet, P., Casteels, M., Fransen, M., Evrard, P., Fahimi, D., Declercq, P. E., Collen, D., et al. (1997) · Nature Genetics · doi:10.1038/ng0997-49 · Cited by 275 · see citing works

The Inflammatory Myelinopathy of Adreno-Leukodystrophy: Cells, Effector Molecules, and Pathogenetic Implications

POWERS, J. M., LIU, Y., MOSER, A. B., & MOSER, H. W. (1992) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199211000-00007 · Cited by 265 · see citing works

Adrenoleukodystrophy: Survey of 303 cases: Biochemistry, diagnosis, and therapy

Moser, H. W., Moser, A. E., Singh, I., & OʼNeill, P. (1984) · Annals of Neurology · doi:10.1002/ana.410160603 · Cited by 259 · see citing works

Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia

Goodenowe, D. B., Cook, L. L., Liu, J., Lu, Y., Jayasinghe, D., Ahiahonu, P. W. K., Heath, D., Yamazaki, Y., Flax, J., Krenitsky, K. F., et al. (2007) · Journal of Lipid Research · doi:10.1194/jlr.p700023-jlr200 · Cited by 253 · see citing works

Decrease and Structural Modifications of Phosphatidylethanolamine Plasmalogen in the Brain with Alzheimer Disease

Guan, Z., Wang, Y., Cairns, N. J., Lantos, P. L., Dallner, G., & Sindelar, P. J. (1999) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199907000-00008 · Cited by 236 · see citing works

Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice

Rodemer, C., Thai, T.-P., Brügger, B., Kaercher, T., Werner, H. B., Nave, K., Wieland, F., Gorgas, K., & Just, W. W. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg191 · Cited by 225 · see citing works

Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy

Pujol, A. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.5.499 · Cited by 214 · see citing works

Adrenomyeloneuropathy: A Neuropathologic Review Featuring Its Noninflammatory Myelopathy

Powers, J. M., DeCiero, D. P., Ito, M., Moser, A. B., & Moser, H. W. (2000) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/59.2.89 · Cited by 204 · see citing works

Peroxisome Biogenesis Disorders

Grønborg, S. W., Gould, S. J., & Valle, D. L. (2003) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.4.070802.110424 · Cited by 203 · see citing works

X-linked adrenoleukodystrophy: Clinical, biochemical and pathogenetic aspects

Berger, J., & Gärtner, J. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.07.010 · Cited by 199 · see citing works

Adrenoleukodystrophy Protein-Deficient Mice Represent Abnormality of Very Long Chain Fatty Acid Metabolism

Kobayashi, T., Shinnoh, N., Kondo, A., & Yamada, T. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6340 · Cited by 197 · see citing works

X-linked adrenoleukodystrophy: Genes, mutations, and phenotypes

Smith, K. D., Kemp, S., Braiterman, L. T., Lu, J.-F., Wei, H.-M., Geraghty, M., Stetten, G., Bergin, J. S., Pevsner, J., & Watkins, P. A. (1999) · Neurochemical Research · doi:10.1023/a:1022535930009 · Cited by 190 · see citing works

Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity.

Seedorf, U., Brysch, P., Engel, T., Schrage, K., & Assmann, G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)31960-9 · Cited by 170 · see citing works

ATP-binding cassette (ABC) transporters in human metabolism and diseases.

Stefkova, J., Poledne, R., & Hubacek, J. A. (2004) · PubMed · Cited by 163 · see citing works

Role of ALDP (ABCD1) and Mitochondria in X-Linked Adrenoleukodystrophy

McGuinness, M. C., Lu, J.-F., Zhang, H.-P., Dong, G.-X., Heinzer, A. K., Watkins, P. A., Powers, J., & Smith, K. D. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.2.744-753.2003 · Cited by 147 · see citing works

Adreno-leukodystrophy: Oxidative Stress of Mice and Men

Powers, J. M., Pei, Z., Heinzer, A. K., Brose, R. D., Moser, A. B., Moser, H. W., Watkins, P. A., & Smith, K. D. (2005) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000190064.28559.a4 · Cited by 131 · see citing works

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata

Brites, P. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg236 · Cited by 116 · see citing works

The peroxisomal ABC transporter family

Wanders, R. J. A., Visser, W. F., van Roermund, C. W. T., Kemp, S., & Waterham, H. R. (2006) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0142-x · Cited by 111 · see citing works

Human ATP-binding cassette (ABC) transporters and lipoprotein metabolism.

Stefkova, J., Poledne, R., & Hubacek, J. A. (2004) · Physiological Research · doi:10.33549/physiolres.930432 · Cited by 109 · see citing works

Rapid stable isotope dilution analysis of very-long-chain fatty acids, pristanic acid and phytanic acid using gas chromatography–electron impact mass spectrometry

Vreken, P., van Lint, A. E. M., Bootsma, A. H., Overmars, H., Wanders, R. J. A., & Gennip, A. H. (1998) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/s0378-4347(98)00186-8 · Cited by 99 · see citing works

Measurement of peroxisomal fatty acid β‐oxidation in cultured human skin fibroblasts

Wanders, R. J. A., Denis, S. W., Ruiter, J. P. N., Schutgens, R. B. H., van Roermund, C. W. T., & Jacobs, B. S. (1995) · Journal of Inherited Metabolic Disease · doi:10.1007/bf00711434 · Cited by 95 · see citing works

Plasma and Red Blood Cell Fatty Acids in Peroxisomal Disorders

Moser, A. B., Jones, D. S., Raymond, G. V., & Moser, H. W. (1999) · Neurochemical Research · doi:10.1023/a:1022549618333 · Cited by 93 · see citing works

Sterol Carrier Protein X (SCPx) Is a Peroxisomal Branched-Chain β-Ketothiolase Specifically Reacting with 3-Oxo-pristanoyl-CoA: A New, Unique Role for SCPx in Branched-Chain Fatty Acid Metabolism in Peroxisomes

Wanders, R. J. A., Denis, S. W., Wouters, F. S., WIRTZ, K. W. A., & Seedorf, U. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7007 · Cited by 90 · see citing works

Membrane Instability, Plasmalogen Content, and Alzheimer's Disease

Ginsberg, L., Xuereb, J. H., & Gershfeld, N. L. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.70062533.x · Cited by 89 · see citing works

Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin

Khan, M., Singh, J., & Singh, I. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05513.x · Cited by 86 · see citing works

Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain

Faust, P. L., Banka, D., Siriratsivawong, R., Ng, V. G., & Wikander, T. M. (2005) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-005-7059-y · Cited by 82 · see citing works

The pathology of peroxisomal disorders with pathogenetic considerations.

Powers, J. M. (1995) · PubMed · Cited by 72 · see citing works

Assay of plasmalogens and polyunsaturated fatty acids (PUFA) in erythrocytes and fibroblasts

Dacremont, G., & Vincent, G. (1995) · Journal of Inherited Metabolic Disease · doi:10.1007/bf00711431 · Cited by 71 · see citing works

Lipid and fatty acid composition of brain tissue from adrenoleukodystrophy patients

Wilson, R., & Sargent, J. R. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03567.x · Cited by 67 · see citing works

PRESIDENTIAL ADDRESS: The Pathology of Peroxisomal Disorders with Pathogenetic Considerations

Powers, J. M. (1995) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199509000-00014 · Cited by 67 · see citing works

Rhizomelic Chondrodysplasia Punctata, a Peroxisomal Biogenesis Disorder Caused by Defects in Pex7p, a Peroxisomal Protein Import Receptor: A Minireview

Purdue, P. E., Skoneczny, M., Yang, X., Zhang, J.-W., & Lazarow, P. B. (1999) · Neurochemical Research · doi:10.1023/a:1023957110171 · Cited by 49 · see citing works

Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse

Huyghe, S., Casteels, M., Janssen, A., MEULDERS, L., Mannaerts, G. P., Declercq, P. E., Veldhoven, P. P. V., & Baes, M. I. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3530673 · Cited by 48 · see citing works

The Neuronal Migration Defect in Mice with Zellweger Syndrome (Pex5Knockout) is not Caused by the Inactivity of Peroxisomal β-Oxidation

Baes, M. I., Gressèns, P., Huyghe, S., Nys, K. D., Qi, C., Jia, Y., Mannaerts, G. P., Evrard, P., Veldhoven, P. P. V., Declercq, P. E., et al. (2002) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/61.4.368 · Cited by 47 · see citing works

Quantitative proteomic comparison of mouse peroxisomes from liver and kidney

Mi, J., Kirchner, E., & Cristobal, S. (2007) · PROTEOMICS · doi:10.1002/pmic.200600638 · Cited by 46 · see citing works

Plasmalogen levels in Gaucher disease.

Moraitou, M., Dimitriou, E., Zafeiriou, D., Reppa, C., Marinakis, T., Sarafidou, J., & Michelakakis, H. (2008) · Blood Cells, Molecules & Diseases · doi:10.1016/j.bcmd.2008.03.007 · Cited by 32 · see citing works

Lessons from Knockout Mice. I: Phenotypes of Mice with Peroxisome Biogenesis Disorders

Baes, M. I., & Veldhoven, P. P. V. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-9072-3_16 · Cited by 9 · see citing works

The mouse as a model to understand peroxisomal biogenesis and its disorders

Brites, P., Wanders, R. J. A., & Waterham, H. R. (2004) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2004.09.003 · Cited by 6 · see citing works

Untitled work

Forss-Petter, S. (1997) · doi:10.1002/(sici)1097-4547(19971201)50:5

Functions of plasmalogen lipids in health and disease

Braverman, N. E., & Moser, A. B. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.05.008 · Cited by 1,082 · see citing works

Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling

Lodhi, I. J., & Semenkovich, C. F. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.01.002 · Cited by 605 · see citing works

Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

Poitelon, Y., Kopec, A. M., & Belin, S. (2020) · Cells · doi:10.3390/cells9040812 · Cited by 394 · see citing works

Myelin Proteomics: Molecular Anatomy of an Insulating Sheath

Jahn, O., Tenzer, S., & Werner, H. B. (2009) · Molecular Neurobiology · doi:10.1007/s12035-009-8071-2 · Cited by 331 · see citing works

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

Chrast, R., Saher, G., Nave, K.-A., & Verheijen, M. H. G. (2011) · Journal of Lipid Research · doi:10.1194/jlr.r009761 · Cited by 314 · see citing works

The peroxisome: an update on mysteries

Islinger, M., Grille, S., Fahimi, H. D., & Schrader, M. (2012) · Histochemistry and Cell Biology · doi:10.1007/s00418-012-0941-4 · Cited by 279 · see citing works

X‐linked adrenoleukodystrophy: Pathology, pathophysiology, diagnostic testing, newborn screening and therapies

Turk, B. R., Theda, C., Fatemi, A. S., & Moser, A. B. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10003 · Cited by 206 · see citing works

Plasmalogen lipids: functional mechanism and their involvement in gastrointestinal cancer

Messias, M. C. F., Mecatti, G. C., Priolli, D. G., & Carvalho, P. D. O. (2018) · Lipids in Health and Disease · doi:10.1186/s12944-018-0685-9 · Cited by 195 · see citing works

Peroxisomes in brain development and function

Berger, J., Dorninger, F., Forss-Petter, S., & Kunze, M. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.12.005 · Cited by 194 · see citing works

Peroxisomal ABC transporters: Structure, function and role in disease

Morita, M., & Imanaka, T. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.02.009 · Cited by 183 · see citing works

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

Agbaga, M.-P., Mandal, M. N. A., & Anderson, R. E. (2010) · Journal of Lipid Research · doi:10.1194/jlr.r005025 · Cited by 167 · see citing works

ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions

Marquez, B., & Françoise Van Bambeke, A. (2011) · Current Drug Targets · doi:10.2174/138945011795378504 · Cited by 165 · see citing works

From peroxisomal disorders to common neurodegenerative diseases – the role of ether phospholipids in the nervous system

Dorninger, F., Forss‐Petter, S., & Berger, J. (2017) · FEBS Letters · doi:10.1002/1873-3468.12788 · Cited by 162 · see citing works

Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients

Wood, P. L., Mankidy, R., Ritchie, S. A., Heath, D., Wood, J. A., Flax, J., & Goodenowe, D. B. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090059 · Cited by 157 · see citing works

Pathomechanisms underlying X-adrenoleukodystrophy: A three-hit hypothesis

Singh, I., & Pujol, A. (2010) · Brain Pathology · doi:10.1111/j.1750-3639.2010.00392.x · Cited by 148 · see citing works

General aspects and neuropathology of X-linked adrenoleukodystrophy

Ferrer, I., Aubourg, P., & Pujol, A. (2010) · Brain Pathology · doi:10.1111/j.1750-3639.2010.00390.x · Cited by 139 · see citing works

A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency

Buchert, R., Tawamie, H., Smith, C., Uebe, S., Innes, A. M., Al Hallak, B., Ekici, A. B., Sticht, H., Schwarze, B., Lamont, R. E., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.10.003 · Cited by 132 · see citing works

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination

da Silva, T. F., Eira, J., Lopes, A. T., Malheiro, A. R., Sousa, V., Luoma, A., Avila, R. L., Wanders, R. J. A., Just, W. W., Kirschner, D. A., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci72063 · Cited by 132 · see citing works

Alkyl-Glycerol Rescues Plasmalogen Levels and Pathology of Ether-Phospholipid Deficient Mice

Brites, P., Ferreira, A. S., da Silva, T. F., Sousa, V., Malheiro, A. R., Durán, M., Waterham, H. R., Baes, M. I., & Wanders, R. J. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028539 · Cited by 130 · see citing works

Plasmalogen synthesis is regulated via alkyl‐dihydroxyacetonephosphate‐synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease

Grimm, M. O. W., Kuchenbecker, J., Rothhaar, T. L., Grösgen, S., Hundsdörfer, B., Burg, V. K., Frieß, P., Müller, U., Grimm, H. S., Riemenschneider, M. J., et al. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07070.x · Cited by 115 · see citing works

Be different—The diversity of peroxisomes in the animal kingdom

Islinger, M., Cardoso, M. J., & Schrader, M. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2010.03.013 · Cited by 115 · see citing works

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

Galea, E., Launay, N., Portero-Otin, M., Ruiz, M., Pamplona, R., Aubourg, P., Ferrer, I., & Pujol, A. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.02.005 · Cited by 108 · see citing works

Novel plasma phospholipid biomarkers of autism: Mitochondrial dysfunction as a putative causative mechanism

Pastural, É., Ritchie, S. A., Lu, Y., Jin, W., Kavianpour, A., Su-Myat, K. K., Heath, D., Wood, P. L., Fisk, M., & Goodenowe, D. B. (2009) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2009.06.003 · Cited by 100 · see citing works

Plasmalogen phospholipids protect internodal myelin from oxidative damage

Luoma, A. M., Kuo, F., Cakici, O., Crowther, M. N., Denninger, A. R., Avila, R. L., Brites, P., & Kirschner, D. A. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.03.012 · Cited by 97 · see citing works

Lipids in regulating oligodendrocyte structure and function

Montani, L. (2020) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2020.07.016 · Cited by 94 · see citing works

The importance of ether-phospholipids: A view from the perspective of mouse models

da Silva, T. F., Sousa, V., Malheiro, A. R., & Brites, P. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.05.014 · Cited by 86 · see citing works

Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL

Sutter, I., Velagapudi, S., Othman, A., Riwanto, M., Manz, J., Rohrer, L., Rentsch, K., Hornemann, T., Landmesser, U., & von Eckardstein, A. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.05.037 · Cited by 82 · see citing works

Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis

Joo, H.-J., Yim, Y., Jeong, P.-Y., Jin, Y.-X., Lee, J.-E., Kim, H., Jeong, S.-K., Chitwood, D. J., & Paik, Y. (2009) · Biochemical Journal · doi:10.1042/bj20090513 · Cited by 82 · see citing works

Oxidative stress and adrenocortical insufficiency

Prasad, R., Kowalczyk, J. C., Meimaridou, E., Storr, H. L., & Metherell, L. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0346 · Cited by 82 · see citing works

Organelle interplay in peroxisomal disorders

Thoms, S., Grønborg, S. W., & Gärtner, J. (2009) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2009.05.002 · Cited by 74 · see citing works

Drosophila models of peroxisomal biogenesis disorder: peroxins are required for spermatogenesis and very-long-chain fatty acid metabolism

Chen, H., Liu, Z., & Huang, X. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp518 · Cited by 67 · see citing works

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

Bottelbergs, A., Verheijden, S., Van Veldhoven, P. P., Just, W., Devos, R., & Baes, M. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-61 · Cited by 66 · see citing works

Mouse models for peroxisome biogenesis defects and β-oxidation enzyme deficiencies

Baes, M. I., & Veldhoven, P. P. V. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.03.003 · Cited by 66 · see citing works

A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton

Braverman, N., Zhang, R., Chen, L., Nimmo, G., Scheper, S., Tran, T., Chaudhury, R., Moser, A., & Steinberg, S. (2010) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2009.12.005 · Cited by 66 · see citing works

Western lifestyle and immunopathology of multiple sclerosis

Matveeva, O., Bogie, J. F. J., Hendriks, J. J. A., Linker, R. A., Haghikia, A., & Kleinewietfeld, M. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13583 · Cited by 61 · see citing works

Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation

Hossain, M. S., Abe, Y., Ali, F., Youssef, M., Honsho, M., Fujiki, Y., & Katafuchi, T. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3941-15.2017 · Cited by 55 · see citing works

Targeting human oligodendrocyte progenitors for myelin repair

Dietz, K. C., Polanco, J. J., Pol, S. U., & Sim, F. J. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.03.017 · Cited by 54 · see citing works

Leukodystrophies with late disease onset: an update

Köhler, W. (2010) · Current Opinion in Neurology · doi:10.1097/wco.0b013e328338313a · Cited by 54 · see citing works

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation

Verheijden, S., Bottelbergs, A., Krysko, O., Krysko, D. V., Beckers, L., De Munter, S., Van Veldhoven, P. P., Wyns, S., Kulik, W., Nave, K.-A., et al. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.06.006 · Cited by 54 · see citing works

Revisiting the neuropathogenesis of Zellweger syndrome

Crane, D. I. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.02.007 · Cited by 51 · see citing works

Emerging role of the endoplasmic reticulum in peroxisome biogenesis

Agrawal, G., & Subramani, S. E. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00286 · Cited by 46 · see citing works

Metabolic dysfunctions in multiple sclerosis: implications as to causation, early detection, and treatment, a case control study

Senanayake, V. K., Jin, W., Mochizuki, A., Chitou, B., & Goodenowe, D. B. (2015) · BMC Neurology · doi:10.1186/s12883-015-0411-4 · Cited by 46 · see citing works

The Role of Plasmalogen in the Oxidative Stability of Neutral Lipids and Phospholipids

Wang, G., & Wang, T. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf903906e · Cited by 42 · see citing works

Leukodystrophy caused by plasmalogen deficiency rescued by glyceryl 1-myristyl ether treatment

Malheiro, A. R., Correia, B., Ferreira da Silva, T., Bessa‐Neto, D., Van Veldhoven, P. P., & Brites, P. (2019) · Brain Pathology · doi:10.1111/bpa.12710 · Cited by 41 · see citing works

Peroxisome Biogenesis Disorders

Honsho, M., Okumoto, K., Tamura, S., & Fujiki, Y. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-60204-8_4 · Cited by 39 · see citing works

Recent advances from metabolomics and lipidomics application in alzheimer’s disease inspiring drug discovery

Čuperlović‐Culf, M., & Badhwar, A. (2019) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1674808 · Cited by 40 · see citing works

Peroxisome deficient invertebrate and vertebrate animal models

Veldhoven, P. P. V., & Baes, M. I. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00335 · Cited by 37 · see citing works

Ascaroside Pheromones: Chemical Biology and Pleiotropic Neuronal Functions

Park, J. Y., Joo, H.-J., Park, S., & Paik, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163898 · Cited by 35 · see citing works

Autism - A Neurodevelopmental Journey from Genes to Behaviour

Eapen, V. (2011) · InTech eBooks · doi:10.5772/974 · Cited by 36 · see citing works

Human and great ape red blood cells differ in plasmalogen levels and composition

Moser, A. B., Steinberg, S. J., Watkins, P. A., Moser, H. W., Ramaswamy, K. A., Siegmund, K. D., Lee, D. R., Ely, J. J., Ryder, O. A., & Hacia, J. G. (2011) · Lipids in Health and Disease · doi:10.1186/1476-511x-10-101 · Cited by 37 · see citing works

Overexpression of peroxisomal testis-specific 1 protein induces germ cell apoptosis and leads to infertility in male mice

Kaczmarek, K., Studencka‐Turski, M., Meinhardt, A., Wieczerzak, K., Thoms, S., Engel, W., & Grzmil, P. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e09-12-0993 · Cited by 33 · see citing works

Tricky Isomers—The Evolution of Analytical Strategies to Characterize Plasmalogens and Plasmanyl Ether Lipids

Koch, J. M., Watschinger, K., Werner, E. R., & Keller, M. A. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.864716 · Cited by 33 · see citing works

Plasmalogens and fatty alcohols in rhizomelic chondrodysplasia punctata and Sjogren-Larsson syndrome.

Malheiro, A. R., da Silva, T. F., & Brites, P. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-014-9795-3 · Cited by 33 · see citing works

Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities

Kawade, N., & Yamanaka, K. (2023) · FEBS Open Bio · doi:10.1002/2211-5463.13661 · Cited by 32 · see citing works

Myelin lesions associated with lysosomal and peroxisomal disorders

Faust, P. L., Kaye, E. M., & Powers, J. M. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.127 · Cited by 31 · see citing works

Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo

Üllen, A., Fauler, G., Köfeler, H. C., Waltl, S., Nusshold, C., Bernhart, E. M., Reicher, H., Leis, H., Wintersperger, A., Malle, E., et al. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.08.025 · Cited by 31 · see citing works

Biosynthesis of ether-phospholipids including plasmalogens, peroxisomes and human disease: new insights into an old problem

Wanders, R. J. A., & Brites, P. (2010) · Clinical Lipidology · doi:10.2217/clp.10.16 · Cited by 26 · see citing works

Genome-Wide Identification and Characterization of WD40 Protein Genes in the Silkworm, Bombyx mori

He, S., Tong, X., Han, M., Hu, H., & Dai, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020527 · Cited by 24 · see citing works

Ccdc33, a Predominantly Testis-Expressed Gene, Encodes a Putative Peroxisomal Protein

Kaczmarek, K., Niedzialkowska, E., Studencka‐Turski, M., Schulz, Y., & Grzmil, P. (2009) · Cytogenetic and Genome Research · doi:10.1159/000251961 · Cited by 24 · see citing works

BACE1 RNAi Restores the Composition of Phosphatidylethanolamine-Derivates Related to Memory Improvement in Aged 3xTg-AD Mice

Villamil-Ortiz, J. G., Barrera-Ocampo, A. A., Piedrahita, D., Velásquez, C., Arias-Londoño, J. D., & Cardona‐Gómez, G. P. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00260 · Cited by 22 · see citing works

The Role of Oxidative Stress and Inflammation in X-Link Adrenoleukodystrophy

Yu, J., Chen, T., Guo, X., Zafar, M. I., Li, H., Wang, Z., & Zheng, J. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.864358 · Cited by 19 · see citing works

Combined deficiency of peroxisomal β-oxidation and ether lipid synthesis in mice causes only minor cortical neuronal migration defects but severe hypotonia

Krysko, O., Bottelbergs, A., Veldhoven, P. V., & Baes, M. (2010) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2010.02.003 · Cited by 17 · see citing works

Analytical methods for (oxidized) plasmalogens: Methodological aspects and applications

Fuchs, B. (2014) · Free Radical Research · doi:10.3109/10715762.2014.999675 · Cited by 17 · see citing works

Impaired plasmalogen synthesis dysregulates liver X receptor-dependent transcription in cerebellum

Honsho, M., Dorninger, F., Abe, Y., Setoyama, D., Ohgi, R., Uchiumi, T., Kang, D., Berger, J., & Fujiki, Y. (2019) · The Journal of Biochemistry · doi:10.1093/jb/mvz043 · Cited by 16 · see citing works

X-linked Adrenoleukodystrophy: Pathology, Pathophysiology, Diagnostic Testing, Newborn Screening, and Therapies

Turk, B. R., Theda, C., Fatemi, A. S., & Moser, A. B. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.11.002 · Cited by 17 · see citing works

Evolution of adrenoleukodystrophy model systems

Ferrer, R. M., Heine, V. M., Kemp, S., & Engelen, M. (2020) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12357 · Cited by 15 · see citing works

Antioxidant Response in Human X-Linked Adrenoleukodystrophy Fibroblasts

Petrillo, S., D’Amico, J., Nicita, F., Torda, C., Vasco, G., Bertini, E., Cappa, M., & Piemonte, F. (2022) · Antioxidants · doi:10.3390/antiox11112125 · Cited by 13 · see citing works

A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity—Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1

Fallatah, W., Cui, W., Pietro, E. D., Carter, G. T., Pounder, B., Dorninger, F., Pifl, C., Moser, A. B., Berger, J., & Braverman, N. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.886316 · Cited by 12 · see citing works

Revisiting the Pathogenesis of X-Linked Adrenoleukodystrophy

Bougnères, P., & Le Stunff, C. (2025) · Genes · doi:10.3390/genes16050590 · Cited by 11 · see citing works

The Effect of a Pex3 Mutation on Hearing and Lipid Content of the Inner Ear

Kochaj, R. M., Martelletti, E., Ingham, N. J., Buniello, A., Sousa, B. C., Wakelam, M. J. O., Lopez‐Clavijo, A. F., & Steel, K. P. (2022) · Cells · doi:10.3390/cells11203206 · Cited by 11 · see citing works

Genetics behind Cerebral Disease with Ocular Comorbidity: Finding Parallels between the Brain and Eye Molecular Pathology

Chang, K.-J., Wu, H.-Y., Yarmishyn, A. A., Li, C.-Y., Hsiao, Y., Chi, Y., Lo, T.-C., Dai, H.-J., Yang, Y., Liu, D.-H., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179707 · Cited by 9 · see citing works

Neuroprotective effect of epidermal growth factor in experimental acrylamide neuropathy: an electrophysiological approach

Pérez-Saad, H., Subirós, N., Berlanga, J., Aldana, L., & del Barco, D. G. (2017) · Journal of the Peripheral Nervous System · doi:10.1111/jns.12214 · Cited by 10 · see citing works

Altered phospholipid molecular species and glycolipid composition in brain, liver and fibroblasts of Zellweger syndrome

Miyazaki, C., Saitoh, M., Itoh, M., Yamashita, S., Miyagishi, M., Takashima, S., Moser, A. B., Iwamori, M., & Mizuguchi, M. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.07.045 · Cited by 9 · see citing works

Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine

Wu, Y., Deng, Y., Angelov, B., & Angelova, A. (2025) · FASEB BioAdvances · doi:10.1096/fba.2025-00010 · Cited by 8 · see citing works

Lipidomic approach towards deciphering anandamide effects in rat decidual cell

Almada, M., Domingues, M. R., Dória, M. L., Fonseca, B. M., Teixeira, N. A. A., & Correia‐da‐Silva, G. (2014) · Journal of Cellular Physiology · doi:10.1002/jcp.24901 · Cited by 8 · see citing works

Peripheral myelin: From development to maintenance

Schumacher, N., Vandenbosch, R., & Franzen, R. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16268 · Cited by 7 · see citing works

Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency

Dorninger, F., Kiss, A., Rothauer, P. J., Stiglbauer-Tscholakoff, A., Kummer, S., Fallatah, W., Perera-Gonzalez, M., Hamza, O., König, T., Bober, M. B., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24031884 · Cited by 6 · see citing works

From lipid function to dysfunction: Very long-chain fatty acids as emerging regulators of neuroinflammatory pathways

Sahu, R. K., Yang, Y., & Chung, H.-L. (2026) · iScience · doi:10.1016/j.isci.2026.114724 · Cited by 5 · see citing works

Mouse Models to Study Peroxisomal Functions and Disorders: Overview, Caveats, and Recommendations

Kocherlakota, S., Swinkels, D., Veldhoven, P. P. V., & Baes, M. I. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3048-8_34 · Cited by 5 · see citing works

Inborn Metabolic Defects of Lysosomes, Peroxisomes, Carbohydrates, Fatty Acids and Mitochondria

Bongarzone, E. R., Givogri, M. I., Vivo, D. C. D., & DiMauro, S. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-374947-5.00043-2 · Cited by 5 · see citing works

Mouse Models of Metachromatic Leukodystrophy and Adrenoleukodystrophy

Aubourg, P. R., Sevin, C., & Cartier, N. (2010) · Neuromethods · doi:10.1007/978-1-60761-898-0_26 · Cited by 5 · see citing works

Role of Lipid Composition on the Mechanical and Biochemical Vulnerability of Myelin and Its Implications for Demyelinating Disorders

Morini, M. A., & Pedroni, V. I. (2025) · Biophysica · doi:10.3390/biophysica5040044 · Cited by 4 · see citing works

Sex-Specific Changes to Brain Fatty Acids, Plasmalogen, and Plasma Endocannabinoids in Offspring Exposed to Maternal and Postnatal High-Linoleic-Acid Diets

Ezechukwu, H. C., Ney, L. J., Jarvis, M. A., Shrestha, N., Holland, O. J., Cuffe, J. S. M., Perkins, A. V., Yau, S., McAinch, A. J., & Hryciw, D. H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147911 · Cited by 3 · see citing works

Acyl-CoA Reductase Far1 Deficiency Impairs Ether Lipid Production and Hypomyelination in Mouse Brains

Takahashi, T., Otsuka, K., Sassa, T., & Kihara, A. (2025) · Molecular and Cellular Biology · doi:10.1080/10985549.2025.2548234 · Cited by 3 · see citing works

Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency

Lotz-Havla, A. S., Woidy, M., Guder, P., Schmiesing, J., Erdmann, R., Waterham, H. R., Muntau, A. C., & Gersting, S. W. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.726174 · Cited by 3 · see citing works

A Mouse Model System to Study Peroxisomal Roles in Neurodegeneration of Peroxisome Biogenesis Disorders

Abe, Y., Tamura, S., Honsho, M., & Fujiki, Y. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-60204-8_10 · Cited by 3 · see citing works

The Biochemical Basis of Autistic Behavior and Pathology

Goodenowe, D. B., & Pastural, É. (2011) · InTech eBooks · doi:10.5772/18571 · Cited by 3 · see citing works

Therapeutics of X-linked adrenoleukodystrophy

Eichler, F., & Aubourg, P. R. (2008) · Drug Discovery Today Therapeutic Strategies · doi:10.1016/j.ddstr.2009.04.002 · Cited by 2 · see citing works

Model Organisms for Understanding Peroxisomal Disorders

Takashima, S., & Shimozawa, N. (2019) · Springer eBooks · doi:10.1007/978-981-15-1169-1_6 · Cited by 2 · see citing works

Peroxisomal Disorders

Wanders, R. J. A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00110-5 · Cited by 2 · see citing works

Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient Pex2 knockout Zellweger mice

Eberhart, T., Charles, K. N., Salumbides-Torres, B., Price, N., Fliesler, S. J., Faust, P. L., & Kovacs, W. J. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2026.1636268 · Cited by 1 · see citing works

Evaluation of BACE1 silencing as a therapy against Alzheimer disease: implications for lipid metabolism and inflammatory response

Villamil-Ortiz, J. G. (2019) · doi:10.33612/diss.99684546 · Cited by 1 · see citing works

Other Peroxisomal Disorders

(2016) · Elsevier eBooks · doi:10.1016/b978-0-323-37754-6.50244-x · Cited by 1 · see citing works

Activités cytotoxiques et pro-oxydantes d'acides gras à très longue chaîne sur des oligodendrocytes murins sauvages et déficients en Abcd1 et Acox1 : application à la physiopathologie de l'X-ALD et de la P-NALD

Baarine, M. (2010) · theses.fr (ABES) · doi:10.70675/7ab2bcc8z16d2z420cz92f9zb3fd52371382 · Cited by 1 · see citing works

Mouse Models with Peroxisome Biogenesis Defects

Baes, M. I., Verheijden, S., & Veldhoven, P. P. V. (2014) · Springer eBooks · doi:10.1007/978-3-7091-1788-0_2

Functional Analysis of Insl5 and Insl6 Genes and Verification of Interactions between Pelota and its Putative Interacting Proteins.

Burnicka-Turek, O. (2009) · eDiss (Georg-August-Universität Göttingen)

Status and Potential Therapeutic Importance of n–3 Fatty Acids in Other Neural and Non-neural Diseases

Farooqui, A. A. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0543-7_10

Ether-linked phosphatidylserine

Leah, E. S. (2010) · Lipidomics Gateway · doi:10.1038/lipidmaps.2009.38

Determination of the role of plasmalogens in the myelination process and myelin maintenance

Eira, J. (2012) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/s6vb-p129

The metabolic profile of phenylbutyric acid and its antioxidant capacity in vervet monkeys

Linde, V. D. R. R., & Johanna, W. (2010)

A JOURNAL OF NEUROLOGY

Brites, P., Mooyer, P. A. W., Mrabet, L. E., Waterham, H. R., & W, R. J. A. (2013)

Very-long-chain polyunsaturated fatty acids accumulate in phosphatidylcholine of fibroblasts from patients with Zellweger syndrome and acyl-CoA oxidase1 deficiency

Abe, Y., Honsho, M., Nakanishi, H., Taguchi, R., & Fujiki, Y. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.01.001 · Cited by 59 · see citing works

Plasma polyenoic very‐long‐chain fatty acids in peroxisomal disease

Poulos, A., Sharp, P. C., & Johnson, D. (1989) · Neurology · doi:10.1212/wnl.39.1.44 · Cited by 17 · see citing works

Dysfunction of peroxisomes as one of the possible causes of multiple organ dysfunction syndrome development

Осипенко, А. Н., & Марочков, А. В. (2014) · Critical Care · doi:10.1186/cc13421

Peroxisomes attenuate cytotoxicity of very long-chain fatty acids

Ali, H., Kobayashi, M., Morito, K., Hasi, R. Y., Aihara, M., Hayashi, J., Kawakami, R., Tsuchiya, K., Sango, K., & Tanaka, T. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159259 · Cited by 15 · see citing works