Lipids in the nervous system: From biochemistry and molecular biology to patho-physiology

CNS synaptogenesis promoted by glia-derived cholesterol

Mauch, D. H., Nägler, K., Schumacher, S., Göritz, C., Müller, E.-C., Otto, A., & Pfrieger, F. W. (2001) · Science · doi:10.1126/science.294.5545.1354 · Cited by 1,711 · see citing works

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβPreprint

Repa, J. J., Liang, G., Ou, J., Bashmakov, Y. K., Lobaccaro, J. A., Shimomura, I., Shan, B., Brown, M. S., Goldstein, J. L., & Mangelsdorf, D. J. (2000) · Genes & Development · doi:10.1101/gad.844900 · Cited by 1,693 · see citing works

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L.-H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O. F., et al. (1999) · Nature Genetics · doi:10.1038/11905 · Cited by 1,687 · see citing works

Protein Sensors for Membrane Sterols

Goldstein, J. L., DeBose‐Boyd, R. A., & Brown, M. S. (2006) · Cell · doi:10.1016/j.cell.2005.12.022 · Cited by 1,685 · see citing works

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J.-C., Deleuze, J.-F., Brewer, H. B., Duverger, N., Denèfle, P., et al. (1999) · Nature Genetics · doi:10.1038/11921 · Cited by 1,433 · see citing works

Cholesterol Modification of Hedgehog Signaling Proteins in Animal Development

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Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

Lehmann, J. M., Kliewer, S. A., Moore, L. B., Smith-Oliver, T. A., Oliver, B. B., Su, J.-L., Sundseth, S. S., Winegar, D. A., Blanchard, D. E., Spencer, T. A., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3137 · Cited by 1,233 · see citing works

High cholesterol level is essential for myelin membrane growth

Saher, G., Brügger, B., Lappe-Siefke, C., Möbius, W., Tozawa, R.-I., Wehr, M. C., Wieland, F., Ishibashi, S., & Nave, K.-A. (2005) · Nature Neuroscience · doi:10.1038/nn1426 · Cited by 799 · see citing works

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

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Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I

Lala, D. S. (1992) · Molecular Endocrinology · doi:10.1210/me.6.8.1249 · Cited by 678 · see citing works

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

Lund, E. G., Guileyardo, J. M., & Russell, D. W. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7238 · Cited by 668 · see citing works

A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s.

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Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

Chakravarthy, M. V., Lodhi, I. J., Yin, L., Malapaka, R. R. V., Xu, H. E., TURK, J. W., & Semenkovich, C. F. (2009) · Cell · doi:10.1016/j.cell.2009.05.036 · Cited by 534 · see citing works

Assembly of CNS Myelin in the Absence of Proteolipid Protein

Klugmann, M., Schwab, M. H., Pühlhofer, A., Schneider, A., Zimmermann, F., Griffiths, I. R., & Nave, K. (1997) · Neuron · doi:10.1016/s0896-6273(01)80046-5 · Cited by 472 · see citing works

Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain

Schönfeld, P., & Reiser, G. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.128 · Cited by 457 · see citing works

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449 · see citing works

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

Hulce, J. J., Cognetta, A. B., Niphakis, M. J., Tully, S. E., & Cravatt, B. F. (2013) · Nature Methods · doi:10.1038/nmeth.2368 · Cited by 428 · see citing works

Biochemistry of the Developing Nervous System

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Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

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Deficiency of ABCA1 Impairs Apolipoprotein E Metabolism in Brain

Hirsch-Reinshagen, V., Zhou, S., Burgess, B. L., Bernier, L., McIsaac, S. A., Chan, J. Y., Tansley, G. H., Cohn, J. S., Hayden, M. R., & Wellington, C. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407962200 · Cited by 385 · see citing works

A Transgenic Rat Model of Charcot-Marie-Tooth Disease

Sereda, M. W., Griffiths, I. R., Pühlhofer, A., Helen, S., Rossner, M. J., Zimmermann, F., Magyar, J. P., Schneider, A., Hund, E., Meinck, H.-M., et al. (1996) · Neuron · doi:10.1016/s0896-6273(00)80128-2 · Cited by 382 · see citing works

Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain

Björkhem, I. (2006) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2006.01725.x · Cited by 381 · see citing works

Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice

Adlkofer, K., Martini, R., Aguzzi, A., Zielasek, J., Toyka, K. V., & Suter, U. (1995) · Nature Genetics · doi:10.1038/ng1195-274 · Cited by 373 · see citing works

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

Sleat, D. E., Wiseman, J. A., El-Banna, M., Price, S. M., Vérot, L., Shen, M. M., Tint, G. S., Vanier, M. T., Walkley, S. U., & Lobel, P. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308456101 · Cited by 365 · see citing works

Mutations in the ABC 1 gene in familial HDL deficiency with defective cholesterol efflux

Marcil, M., Brooks-Wilson, A. R., Clee, S. M., Roomp, K., Zhang, L., Yu, L., Collins, J. A., van Dam, M., Molhuizen, H. O. F., Loubster, O., et al. (1999) · The Lancet · doi:10.1016/s0140-6736(99)07026-9 · Cited by 351 · see citing works

Emerging roles of resolvins in the resolution of inflammation and pain

Ji, R., Xu, Z., Strichartz, G. R., & Serhan, C. N. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.08.005 · Cited by 345 · see citing works

Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

Vance, J. E. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.010124 · Cited by 342 · see citing works

Metabolic signaling by lactate in the brain

Barros, L. F. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.04.002 · Cited by 326 · see citing works

Protein zero (P0)–deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies

Martini, R., Zielasek, J., Toyka, K. V., Giese, K.-P., & Schachner, M. (1995) · Nature Genetics · doi:10.1038/ng1195-281 · Cited by 318 · see citing works

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

Chrast, R., Saher, G., Nave, K.-A., & Verheijen, M. H. G. (2011) · Journal of Lipid Research · doi:10.1194/jlr.r009761 · Cited by 314 · see citing works

Myelin synthesis in the peripheral nervous system

Garbay, B. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00049-0 · Cited by 308 · see citing works

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

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Central nervous system myelin: structure, synthesis and assembly

Aggarwal, S., Yurlova, L., & Simons, M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.06.004 · Cited by 301 · see citing works

Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration

Wang, L., Schuster, G. U., Hultenby, K. R., Zhang, Q., Andersson, S., & Gustafsson, J.-Α. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172510899 · Cited by 286 · see citing works

Neural circuitry engaged by prostaglandins during the sickness syndrome

Saper, C. B., Romanovsky, A. A., & Scammell, T. E. (2012) · Nature Neuroscience · doi:10.1038/nn.3159 · Cited by 285 · see citing works

The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

Keitel, V., Görg, B., Bidmon, H. J., Zemtsova, I., Spomer, L., Zilles, K., & Häussinger, D. (2010) · Glia · doi:10.1002/glia.21049 · Cited by 274 · see citing works

Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred

Remaley, A. T., Rust, S., Rosier, M., Knapper, C., Naudin, L., Broccardo, C., Peterson, K. M., Koch, C., Reguigne-Arnould, I., Prades, C., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12685 · Cited by 269 · see citing works

The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator ofN-Methyl-d-Aspartate Receptors

Paul, S. M., Doherty, J., Robichaud, A. J., Belfort, G. M., Chow, B. Y., Hammond, R., Crawford, D. C., Linsenbardt, A. J., Shu, H., Izumi, Y., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2619-13.2013 · Cited by 267 · see citing works

Brain cholesterol turnover required for geranylgeraniol production and learning in mice

Kotti, T. J., Ramirez, D. M. O., Pfeiffer, B. E., Huber, K. M., & Russell, D. W. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600316103 · Cited by 259 · see citing works

Role of mitochondria in steroidogenesis

Papadopoulos, V., & Miller, W. L. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2012.05.002 · Cited by 249 · see citing works

Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection

Bazan, N. G. (2007) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e32802b7030 · Cited by 244 · see citing works

Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero

Chirala, S. S., Chang, H., Matzuk, M. M., Abu-Elheiga, L. A., Mao, J., Mahon, K., Finegold, M. J., & Wakil, S. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0931394100 · Cited by 242 · see citing works

Functional Loss of ABCA1 in Mice Causes Severe Placental Malformation, Aberrant Lipid Distribution, and Kidney Glomerulonephritis As Well As High-Density Lipoprotein Cholesterol Deficiency

Christiansen-Weber, T. A., Voland, J. R., Wu, Y., Ngo, K., Roland, B. L., Nguyen, S., Peterson, P. A., & Fung‐Leung, W. (2000) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64614-7 · Cited by 236 · see citing works

Neuroactive steroids: State of the art and new perspectives

Melcangi, R. C., García‐Segura, L. M., & Mensah‐Nyagan, A. G. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7403-5 · Cited by 232 · see citing works

Translocator Protein/Peripheral Benzodiazepine Receptor Is Not Required for Steroid Hormone Biosynthesis

Morohaku, K., Pelton, S. H., Daugherty, D. J., Butler, W. R., Deng, W., & Selvaraj, V. (2013) · Endocrinology · doi:10.1210/en.2013-1556 · Cited by 230 · see citing works

Estrogen Receptor Protein Interaction with Phosphatidylinositol 3-Kinase Leads to Activation of Phosphorylated Akt and Extracellular Signal-Regulated Kinase 1/2 in the Same Population of Cortical Neurons: A Unified Mechanism of Estrogen Action

Mannella, P., & Brinton, R. D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1443-06.2006 · Cited by 213 · see citing works

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

Bogdanović, N., Brétillon, L., Lund, E. G., Diczfalusy, U., Lannfelt, L., Winblad, B. G., Russell, D. W., & Björkhem, I. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02277-7 · Cited by 213 · see citing works

Brain fatty acid synthase activates PPARα to maintain energy homeostasis

Chakravarthy, M. V., Zhu, Y., López, M., Yin, L., Wozniak, D. F., Coleman, T., Hu, Z., Wolfgang, M. J., Vidal‐Puig, A., Lane, M. D., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31183 · Cited by 207 · see citing works

Adeno-associated Virus Gene Therapy With Cholesterol 24-Hydroxylase Reduces the Amyloid Pathology Before or After the Onset of Amyloid Plaques in Mouse Models of Alzheimer's Disease

Hudry, E., Dam, D. V., Kulik, W., Deyn, P. P. D., Stet, F. S., Ahouansou, O., Benraiss, A., Delacourte, A., Bougneres, P. F., Aubourg, P. R., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.175 · Cited by 196 · see citing works

Local regulation of fat metabolism in peripheral nervesPreprint

Verheijen, M. H. G., Chrast, R., Burrola, P., & Lemke, G. (2003) · Genes & Development · doi:10.1101/gad.1116203 · Cited by 190 · see citing works

Nutrition and neurodegeneration: epidemiological evidence and challenges for future research

Guyonnet, S., Secher, M., & Vellas, B. J. (2013) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12058 · Cited by 187 · see citing works

Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis

Macedo, A. F., Taylor, F. C., Casas, J. P., Adler, A. J., Prieto‐Merino, D., & Ebrahim, S. B. J. (2014) · BMC Medicine · doi:10.1186/1741-7015-12-51 · Cited by 183 · see citing works

Generation of Viable Cholesterol-Free Mice

Wechsler, A. S., Brafman, A., Shafir, M., Heverin, M., Gottlieb, H., Damari, G. M., Gozlan-Kelner, S., Spivak, I., Moshkin, O., Fridman, E., et al. (2003) · Science · doi:10.1126/science.1090776 · Cited by 179 · see citing works

Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice

Andersson, S., Gustafsson, N., Warner, M. N., & Gustafsson, J.-Α. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500634102 · Cited by 168 · see citing works

Fatty acid transport into the brain: Of fatty acid fables and lipid tails

Mitchell, R. W., & Hatch, G. M. (2011) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2011.04.007 · Cited by 167 · see citing works

Prostaglandins as inflammatory messengers across the blood-brain barrier

Engblom, D., Ek, M., Saha, S., Ericsson‐Dahlstrand, A., Jakobsson, P., & Blomqvist, A. G. (2002) · Journal of Molecular Medicine · doi:10.1007/s00109-001-0289-z · Cited by 167 · see citing works

Transfer of omega‐3 fatty acids across the blood–brain barrier after dietary supplementation with a docosahexaenoic acid‐rich omega‐3 fatty acid preparation in patients with A lzheimer's disease: the O meg AD study

Freund‐Levi, Y., Vedin, I., Cederholm, T., Basun, H., Irving, G. F., Eriksdotter, M., Hjorth, E., Schultzberg, M., Vessby, B., Wahlund, L., et al. (2013) · Journal of Internal Medicine · doi:10.1111/joim.12166 · Cited by 165 · see citing works

Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith--Lemli--Opitz syndrome

Wassif, C. A. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.6.555 · Cited by 164 · see citing works

On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity

Baron, W., & Hoekstra, D. (2010) · FEBS Letters · doi:10.1016/j.febslet.2009.10.085 · Cited by 162 · see citing works

The Estrogen Trinity: Membrane, Cytosolic, and Nuclear Effects

Nadal, Ã., Díaz, M. L., & Valverde, M. A. (2001) · Physiology · doi:10.1152/physiologyonline.2001.16.6.251 · Cited by 159 · see citing works

Sonic hedgehog in the nervous system: functions, modifications and mechanisms

Ho, K. S., & Scott, M. P. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00290-8 · Cited by 155 · see citing works

7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome

Fitzky, B. U., Moebius, F. F., Asaoka, H., Waage-Baudet, H., Xu, L., Xu, G., Maeda, N., Kluckman, K. D., Hiller, S., Yu, H., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112103 · Cited by 153 · see citing works

P0 Glycoprotein Overexpression Causes Congenital Hypomyelination of Peripheral Nerves

Wrabetz, L. G., Feltri, M. L., Quattrini, A., Imperiale, D., Previtali, S. C., D’Antonio, M., Martini, R., Yin, X., Trapp, B. D., Zhou, L., et al. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.148.5.1021 · Cited by 152 · see citing works

Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function

Karasinska, J. M., Rinninger, F., Lütjohann, D., Ruddle, P., Franciosi, S., Kruit, J. K., Singaraja, R. R., Hirsch‐Reinshagen, V., Fan, J., Brunham, L. R., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4741-08.2009 · Cited by 151 · see citing works

7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome

Fitzky, B. U., Moebius, F. F., Asaoka, H., Waage-Baudet, H., Xu, L., Xu, G., Maeda, N., Kluckman, K. D., Hiller, S., Yu, H., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12103 · Cited by 150 · see citing works

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

Theofilopoulos, S., Wang, Y., Kitambi, S. S., Sacchetti, P., Sousa, K. M., Bodin, K., Kirk, J. M., Saltó, C., Gustafsson, M., Toledo, E. M., et al. (2012) · Nature Chemical Biology · doi:10.1038/nchembio.1156 · Cited by 132 · see citing works

Cerebrospinal Fluid Steroidomics: Are Bioactive Bile Acids Present in Brain?

Ogundare, M., Theofilopoulos, S., Lockhart, A., Hall, L. J., Arenas, E., Sjövall, J., Brenton, A. G., Wang, Y., & Griffiths, W. J. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.086678 · Cited by 128 · see citing works

Cholesterol Regulates the Endoplasmic Reticulum Exit of the Major Membrane Protein P0 Required for Peripheral Myelin Compaction

Saher, G., Quintes, S., Möbius, W., Wehr, M. C., Krämer‐Albers, E., Brügger, B., & Nave, K. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0686-09.2009 · Cited by 127 · see citing works

A novel mouse model of Niemann–Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations

Maue, R. A., Burgess, R. W., Wang, B., Wooley, C. M., Seburn, K. L., Vanier, M. T., Rogers, M. A., Chang, C. C. Y., Chang, T., Harris, B. T., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr505 · Cited by 127 · see citing works

Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation

Hermanson, D. J., Hartley, N. D., Gamble-George, J., Brown, N., Shonesy, B. C., Kingsley, P. J., Colbran, R. J., Reese, J., Marnett, L. J., & Patel, S. (2013) · Nature Neuroscience · doi:10.1038/nn.3480 · Cited by 126 · see citing works

Embryonic Lethality and Defective Neural Tube Closure in Mice Lacking Squalene Synthase

Tozawa, R., Ishibashi, S., Osuga, J.-I., Yagyu, H., Oka, T., Chen, Z., Ohashi, K., Perrey, S., Shionoiri, F., Yahagi, N., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.43.30843 · Cited by 125 · see citing works

Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions

Melcangi, R. C., Giatti, S., Calabrese, D., Pesaresi, M., Cermenati, G., Mitro, N., Viviani, B., García‐Segura, L. M., & Caruso, D. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.07.006 · Cited by 124 · see citing works

SCAP is required for timely and proper myelin membrane synthesis

Verheijen, M. H. G., Camargo, N., Verdier, V., Nadra, K., de Preux Charles, A.-S., Médard, J.-J., Luoma, A., Crowther, M., Inouye, H., Shimano, H., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905633106 · Cited by 119 · see citing works

Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann‐Pick C disease

German, D. C., Quintero, E. M., Liang, C., Ng, B., Punia, S., Xie, C., & Dietschy, J. M. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1149 · Cited by 118 · see citing works

Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids

Rouzer, C. A., & Marnett, L. J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r800005200 · Cited by 116 · see citing works

Sex differences in neuroactive steroid levels in the nervous system of diabetic and non-diabetic rats

Pesaresi, M., Maschi, O., Giatti, S., García‐Segura, L. M., Caruso, D., & Melcangi, R. C. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.04.008 · Cited by 114 · see citing works

A critical role for the cholesterol‐associated proteolipids PLP and M6B in myelination of the central nervous system

Werner, H., Krämer-Albers, E.-M., Strenzke, N., Saher, G., Tenzer, S., Ohno-Iwashita, Y., de Monasterio-Schrader, P., Möbius, W., Moser, T., Griffiths, I., et al. (2013) · Glia · doi:10.1002/glia.22456 · Cited by 111 · see citing works

Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain

Strauss, K. I. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.09.011 · Cited by 105 · see citing works

Peripheral nerves: a target for the action of neuroactive steroids

Melcangi, R. C., Cavarretta, I. T. R., Ballabio, M., Leonelli, E., Schenone, A. E., Azcoitia, Í., García‐Segura, L. M., & Magnaghi, V. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.12.021 · Cited by 105 · see citing works

Expression of liver X receptor β is essential for formation of superficial cortical layers and migration of later-born neurons

Fan, X., Kim, H.-J., Bouton, D., Warner, M., & Gustafsson, J.-Å. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806974105 · Cited by 103 · see citing works

Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin

Yu, T., & Lieberman, A. P. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003462 · Cited by 102 · see citing works

Evaluation of neuroactive steroid levels by liquid chromatography–tandem mass spectrometry in central and peripheral nervous system: Effect of diabetes

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Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

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Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain

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Justification of rational and safe biotechnological methods of using fat additives from vegetable raw materials

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Nervonic acid in infant nutrition: a forward-looking approach to enhancing neurodevelopmental outcomes

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Erythrocyte Plasma Membrane Lipid Composition Mirrors That of Neurons and Glial Cells in Murine Experimental In Vitro and In Vivo Inflammation

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Astrocytic functions and lipid metabolism: Correlations and therapeutic targets in Alzheimer's disease and glioblastoma

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Effects of Sevoflurane Anesthesia on Cerebral Lipid Metabolism in the Aged Brain of Marmosets and Mice

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The Effects of Consuming White Button Mushroom Agaricus bisporus on the Brain and Liver Metabolome Using a Targeted Metabolomic Analysis

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Editorial to the Special Issue “Lipidomics and Neurodegenerative Diseases”

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Exploratory profiling of metabolites in cerebrospinal fluid using a commercially available targeted LC-MS based metabolomics kit to discriminate leptomeningeal metastasis

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Division of Labor among Worker Bees Is Associated with the Lipidomic Plasticity in Their Brains

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Neuroprotective Effects of Metformin Through AMPK Activation in a Neurotoxin-Based Model of Cerebellar Ataxia

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Discovery of Delirium Biomarkers through Minimally Invasive Serum Molecular Fingerprinting

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Development of an LC-MS/MS Method to Measure Sphingolipids in CSF from Patients with Multiple Sclerosis

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Imaging and Genetic Tools for the Investigation of the Endocannabinoid System in the CNS

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Identifying mRNAs Residing in Myelinating Oligodendrocyte Processes as a Basis for Understanding Internode Autonomy

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Traumatic brain injury from a peripheral axis perspective: Uncovering the roles of liver and adipose tissue in temperature regulation

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Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

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Mechanisms of Radiation-induced Brain Injury in Mice Based on Bioinformatics Analysis

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