Long-term storage of lipid-like nanoparticles for mRNA delivery

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High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing

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<i>In Vitro</i> and <i>in Vivo</i> mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles

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Lipid nanoparticles for delivery of messenger RNA to the back of the eye

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Dendrimer‐Based Lipid Nanoparticles Deliver Therapeutic FAH mRNA to Normalize Liver Function and Extend Survival in a Mouse Model of Hepatorenal Tyrosinemia Type I

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Recent advances and further challenges in lyophilization

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Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy.

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Nanoscale platforms for messenger RNA delivery

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Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format

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Short- and long-term stability study of lyophilized solid lipid nanoparticles for gene therapy

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Biomedical applications of mRNA nanomedicine

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Multifunctional triblock copolymers for intracellular messenger RNA delivery

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Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications

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Lipid Polymer Hybrid Nanomaterials for mRNA Delivery

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RNA delivery biomaterials for the treatment of genetic and rare diseases

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The effect of annealing and cryoprotectants on the properties of vacuum-freeze dried starch nanoparticles

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Optimization of the lyophilization process for long-term stability of solid–lipid nanoparticles

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Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer

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Therapeutic mRNA delivery to leukocytes

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Effect of cryoprotectants on the reconstitution of surfactant-free nanoparticles of poly(DL-lactide-co-glycolide)

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Preparation of redispersible liposomal dry powder using an ultrasonic spray freeze-drying technique for transdermal delivery of human epithelial growth factor

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Understanding the Freezing of Biopharmaceuticals: First-Principle Modeling of the Process and Evaluation of Its Effect on Product Quality

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Disorder and twinning in molecular crystals: impurity‐induced effects in adipic acid

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Effect of Freezing Rate on Physical Stability of Lyophilized Cationic Liposomes

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Lipid nanoparticles for mRNA delivery

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mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability

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Drug delivery systems for RNA therapeutics

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Chemistry of Lipid Nanoparticles for RNA Delivery

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The clinical progress of mRNA vaccines and immunotherapies

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Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development

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Nanomaterial Delivery Systems for mRNA Vaccines

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Addressing the Cold Reality of mRNA Vaccine Stability

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Self-assembled mRNA vaccines

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A Comprehensive Review of mRNA Vaccines

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Challenges of Storage and Stability of mRNA-Based COVID-19 Vaccines

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Nucleic acid delivery for therapeutic applications

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Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

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Principles for designing an optimal mRNA lipid nanoparticle vaccine

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Lipid Nanoparticle–mRNA Formulations for Therapeutic Applications

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Freeze-drying of nanoparticles: How to overcome colloidal instability by formulation and process optimization

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The Storage and In-Use Stability of mRNA Vaccines and Therapeutics: Not A Cold Case

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Lipid nanoparticles for siRNA delivery in cancer treatment

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Theoretical basis for stabilizing messenger RNA through secondary structure design

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A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines

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Combinatorial development of nebulized mRNA delivery formulations for the lungs

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Recent Advances in Lipid Nanoparticles for Delivery of mRNA

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Nanotechnology-based mRNA vaccines

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Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures

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Optimization of storage conditions for lipid nanoparticle-formulated self-replicating RNA vaccines

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Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

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mRNA in the Context of Protein Replacement Therapy

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Design of lipid-based nanoparticles for delivery of therapeutic nucleic acids

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A Bio‐Inspired Multifunctional Hydrogel Network with Toughly Interfacial Chemistry for Dendrite‐Free Flexible Zinc Ion Battery

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Engineering therapeutical extracellular vesicles for clinical translation

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From structural design to delivery: mRNA therapeutics for cancer immunotherapy

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Advances in mRNA non-viral delivery approaches

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Current Developments and Challenges of mRNA Vaccines

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Tailoring combinatorial lipid nanoparticles for intracellular delivery of nucleic acids, proteins, and drugs

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Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach

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The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid‐Based Nanoparticles for mRNA and DNA Delivery

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Engineering nanoparticle toolkits for mRNA delivery

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Stabilizing vaccines via drying: Quality by design considerations

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A flexible, thermostable nanostructured lipid carrier platform for RNA vaccine delivery

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A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability

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In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy

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Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applications

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The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism

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mRNA-Based Vaccines and Therapeutics for COVID-19 and Future Pandemics

Chavda, V. P., Soni, S., Vora, L. K., Soni, S., Khadela, A. D., & Ajabiya, J. (2022) · Vaccines · doi:10.3390/vaccines10122150 · Cited by 82 · see citing works

Circular RNA vaccines with long-term lymph node-targeting delivery stability after lyophilization induce potent and persistent immune responses

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A comprehensive comparison of DNA and RNA vaccines

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Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates

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Plant-Derived Extracellular Vesicles: A New Revolutionization of Modern Healthy Diets and Biomedical Applications

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Lyophilization process optimization and molecular dynamics simulation of mRNA-LNPs for SARS-CoV-2 vaccine

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Efficient hepatic delivery and protein expression enabled by optimized mRNA and ionizable lipid nanoparticle

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Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids

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Enzyme-Catalyzed One-Step Synthesis of Ionizable Cationic Lipids for Lipid Nanoparticle-Based mRNA COVID-19 Vaccines

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Spray dried lipid nanoparticle formulations enable intratracheal delivery of mRNA

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