Cited by 186Skin Protection and Agingmelanin and skin pigmentationPhytochemicals and Antioxidant Activities

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Natural components in sunscreens: Topical formulations with sun protection factor (SPF)

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He, hailun, Li, anqi, Li, shiqin, Tang, jie, Li, li, Xiong, lidan·2021·Biomedicine & Pharmacotherapy

DOI 10.1016/j.biopha.2020.111161

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Abstract

Artificial sunscreens are already gaining traction in order to protect the skin from sunburns, photoaging and photocarcinogenesis. However, the efficacy and safety of most artificial sunscreen constituents are hindered by their photostability, toxicity and damage to marine ecosystems. Natural selection and evolution have ensured that plants and animals have developed effective protective mechanisms against the deleterious side effects of oxidative stress and ultraviolet radiation (UV). Hence, natural antioxidants such as sun blockers are drawing considerable attention. The exact mechanism by which natural components act as sunscreen molecules has not been clearly established. However, conjugated π system is reported to play an important role in protecting the vital genetic material within the organism. Compared to artificial sunscreens, natural sunscreens with strong UV absorptive capacities are largely limited by low specific extinction value and by their inability to spread in large-scale sunscreen cosmetic applications. Previous studies have documented that natural components exert their photoprotective effects (such as improved skin elasticity and hydration, skin texture, and wrinkles) through their antioxidant effects, and through the regulation of UV-induced skin inflammation, barrier impairment and aging. This review focuses on natural antioxidant topical formulations with sun protection factor (SPF). Lignin, melanin, silymarin and other ingredients have been added to high sun protection nature sunscreens without any physical or chemical UV filters. This paper also provides a reference for adopting novel technical measures (extracting high content components, changing the type of solution, optimizing formulation, applying Nano technology, et al) to design and prepare nature sunscreen formulations equated with commercial sunscreen formulations. Another strategy is to add natural antioxidants from plants, animals, microorganisms and marine organisms as special enhancer or modifier ingredients to reinforce SPF values. Although the photoprotective effects of natural components have been established, their deleterious side effects have not been elucidated.

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Fig. 2 Possible mechanisms by which natural compounds exert their photo chemical properties. Jablonski diagram. S: singlet state; T: triplet state; IC: in ternal conversion; and ISC: intersystem crossing. CI: conical intersections.CC-BY-NC-ND · From the PDF

Fig. 1 Schematic representation of the impact of ROS on skin damage.CC-BY-NC-ND · From the PDF

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RETRACTED: Amelioration of UV radiation-induced photoaging by a combinational sunscreen formulation via aversion of oxidative collagen degradation and promotion of TGF-β-Smad-mediated collagen production
Bora, N. S., Mazumder, B., Mandal, S., Patowary, P., Goyary, D., Chattopadhyay, P., & Dwivedi, S. K. (2018) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2018.11.004 · Cited by 25
Retracted
UV-induced DNA damage and repair: a review
Sinha, R. P., & Häder, D.-P. (2002) · Photochemical & Photobiological Sciences · doi:10.1039/b201230h · Cited by 1,978
A role for sunlight in skin-cancer – UV-induced p53 mutations in squamous-cell carcinoma
Brash, D. E., Rudolph, J. A., Simon, J. A., Lin, A., McKenna, G. J., Baden, H. P., Halperin, A. J., & Pontén, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.10124 · Cited by 1,959
Vitamin D for health: a global perspective
Hossein-nezhad, A., & Holick, M. F. (2013) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2013.05.011 · Cited by 1,298
Toxic effects of ultraviolet radiation on the skin
Matsumura, Y., & Ananthaswamy, H. N. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2003.08.019 · Cited by 1,270
Oxidation events and skin aging
Kammeyer, A., & Luiten, R. M. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.01.001 · Cited by 980
Life and the Evolution of Earth's Atmosphere
Kasting, J. F., & Siefert, J. L. (2002) · Science · doi:10.1126/science.1071184 · Cited by 514
Evidence Regarding the UV Sunscreen Role of a Mycosporine-Like Compound in the Cyanobacterium Gloeocapsa sp
García‐Pichel, F., Wingard, C. E., & Castenholz, R. W. (1993) · Applied and Environmental Microbiology · doi:10.1128/aem.59.1.170-176.1993 · Cited by 314
Review of environmental effects of oxybenzone and other sunscreen active ingredients
Schneider, S., & Lim, H. (2019) · Journal of American Academy of Dermatology · doi:10.1016/j.jaad.2018.06.033 · Cited by 297
Solar ultraviolet radiation-induced DNA damage in aquatic organisms: potential environmental impact
Häder, D.-P., & Sinha, R. P. (2005) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2004.11.017 · Cited by 226

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Authors: He, H., Li, A., Li, S., Tang, J., Li, L., & Xiong, L.
Affiliations: Sichuan University (CN)
Corresponding author: Xiong, lidan
ORCID: He, hailun
Tang, jie
Li, li
Xiong, lidan
Venue: Biomedicine & Pharmacotherapy
Publisher: Elsevier BV
Published: 2021-02
Volume: 134
Pages: 111161
ISSN: 0753-3322 (ISSN-L)
DOI: 10.1016/j.biopha.2020.111161
OpenAlex: W3115421294
Cited by: 186
References: 105
Citations by year: 2026: 23 · 2025: 36 · 2024: 39 · 2023: 38 · 2022: 28 · 2021: 20
FWCI: 3.64
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Locations: Biomedicine & Pharmacotherapy (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: West China Hospital, Sichuan University
Topics: Health Sciences › Medicine › Dermatology › Skin Protection and Aging
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Keywords: natural sunscreen, sun protection factor, topical formulation, UV protection, photoprotection, natural antioxidants, lignin, melanin, silymarin, skin inflammation, photostability
MeSH terms: Administration, Cutaneous, Animals, Antioxidants, Humans, Plant Extracts, Plants, Medicinal, Skin, Sunburn, Sunscreening Agents, Ultraviolet Rays, Skin Aging, Oxidative Stress

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Natural components in sunscreens: Topical formulations with sun protection factor (SPF)

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