Sensory Contributions to Impaired Prosodic Processing in Schizophrenia
Abstract
Background Deficits in affect recognition are prominent features of schizophrenia. Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated.Methods Forty-three patients and 34 healthy comparison subjects were tested on two affective prosody measures: voice emotion identification and voice emotion discrimination. Basic auditory sensory processing was measured using a tone-matching paradigm and the Distorted Tunes Test (DTT). A subset of subjects was also tested on facial affect identification and discrimination tasks.Results Patients showed significantly impaired performance on all emotion processing tasks. Within the patient group, a principal components analysis demonstrated significant intercorrelations between basic pitch perception and affective prosodic performance. In contrast, facial affect recognition deficits represented a distinct second component. Prosodic affect measures correlated significantly with severity of negative symptoms and impaired global outcome.Conclusions These results demonstrate significant relationships between basic auditory processing deficits and impaired receptive prosody in schizophrenia. The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia.
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Deficits in tone matching contribute significantly to ability to detect emotional prosody.
“Deficits in tone matching contribute significantly to ability to detect emotional prosody (74, 75)”
From Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia (2015) · cites this paper as [75]
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- Authors
- Leitman, D. I., Foxe, J. J., Butler, P. D., Saperstein, A., Revheim, N., & Javitt, D. C.
- Affiliations
- Nathan Kline Institute for Psychiatric Research (US)
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2005-07
- Volume
- 58
- Issue
- 1
- Pages
- 56-61
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2056904033
- Cited by
- 206
- References
- 52
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 5 · 2023: 10 · 2022: 6 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 13 · 2017: 8 · 2016: 16 · 2015: 14 · 2014: 10 · 2013: 20 · 2012: 18
- FWCI
- 4.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 63434, MH-65350, F1-MH-067339, K02-MH-01439, R01 MH49334, R01MH065350, F31MH067339, R03MH063434, R01MH049334, K02MH001439)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- schizophrenia, affect recognition, prosody, auditory sensory processing, pitch perception, facial expression recognition, negative symptoms, global outcomes
- MeSH terms
- Adult, Auditory Perception, Discrimination, Psychological, Emotions, Facial Expression, Female, Form Perception, Humans, Male, Neuropsychological Tests, Pitch Discrimination, Psychiatric Status Rating Scales, Schizophrenia, Schizophrenic Psychology, Speech Acoustics, Speech Perception, Verbal Behavior, Visual Perception, Voice, Recognition, Psychology
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