Photoprotective activity of resveratrol analogues
Abstract
Resveratrol is a promising agent for protecting human skin from UV radiation and to reduce the occurrence of cutaneous malignancies. We describe the photoprotective activity of six resveratrol analogues using the diffuse transmittance technique to determine the SPF and the protection against UVA radiation. The analogues presented a varied profile of photoprotection, the SPF ranging from 2 to 10 and the UVAPF from 0 to 9. Among the six compounds tested, the protection against UVB sunrays provided by compound B was more significant than the protection provided by resveratrol; compounds C, D, E and F show photoprotection similar to resveratrol.
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All compounds 126-141 revealed promising UV filter properties, with SPF values between 2 and 20.
“All compounds revealed promising UV filter properties, with SPF values between 2 and 20 [139].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [139]
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- Authors
- Polonini, H. C., Lima, L. L., Gonçalves, K. M., do Carmo, A. M. R., da Silva, A. D., & Raposo, N. R. B.
- Affiliations
- Universidade Federal de Juiz de Fora (BR)
- Corresponding author
- Raposo, Nádia Rezende Barbosa
- ORCID
- Venue
- Bioorganic & Medicinal Chemistry
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 21
- Issue
- 4
- Pages
- 964-968
- ISSN
- 0968-0896 (ISSN-L)
- OpenAlex
- W2079196438
- Cited by
- 50
- References
- 16
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 6 · 2021: 4 · 2020: 2 · 2019: 4 · 2018: 7 · 2017: 4 · 2016: 4 · 2015: 4 · 2014: 5 · 2013: 2
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Bioorganic & Medicinal Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Sirtuins and Resveratrol in Medicine
- Physical Sciences › Materials Science › Materials Chemistry › Photochromic and Fluorescence Chemistry
- Keywords
- resveratrol analogues, photoprotection, sun protection factor, UVA protection, UVB protection, skin photoprotection, skin cancer, ultraviolet radiation
- MeSH terms
- Resveratrol, Humans, Skin, Stilbenes, Structure-Activity Relationship, Sunscreening Agents, Ultraviolet Rays, Sun Protection Factor
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