Influence of fermented milk products, prebiotics and probiotics on microbiota composition and health

Ceapa, Corina; Wopereis, Harm; Rezaïki, Lahcene; Kleerebezem, Michiel; Knol, Jan; Oozeer, Raish

doi:10.1016/j.bpg.2013.04.004

Cited by 98Probiotics and Fermented FoodsGut microbiota and healthMicrobial Metabolites in Food Biotechnology

Influence of fermented milk products, prebiotics and probiotics on microbiota composition and health

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Ceapa, Corina, Wopereis, Harm, Rezaïki, Lahcene, Kleerebezem, Michiel, Knol, Jan, Oozeer, Raish·2013·Best Practice & Research Clinical Gastroenterology

DOI 10.1016/j.bpg.2013.04.004

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Abstract

The gut microbiota is a highly diverse and relative stabile ecosystem increasingly recognized for its impact on human health. The homeostasis of microbes and the host is also referred to as eubiosis. In contrast, deviation from the normal composition, defined as dysbiosis, is often associated with localized diseases such as inflammatory bowel disease or colonic cancer, but also with systemic diseases like metabolic syndrome and allergic diseases. Modulating a gut microbiota dysbiosis with nutritional concepts may contribute to improving health status, reducing diseases or disease symptoms or supporting already established treatments. The gut microbiota can be modulated by different nutritional concepts, varying from specific food ingredients to complex diets or by the ingestion of particular live microorganisms. To underpin the importance of bacteria in the gut, we describe molecular mechanisms involved in the crosstalk between gut bacteria and the human host, and review the impact of different nutritional concepts such as pre-, pro- and synbiotics on the gastrointestinal ecosystem and their potential health benefits. The aim of this review is to provide examples of potential nutritional concepts that target the gut microbiota to support human physiology and potentially health outcomes.

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Crossref · 10.1016/j.bpg.2013.04.004

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Probiotics for the prevention of pediatric antibiotic-associated diarrhea
Johnston, B. C., Goldenberg, J. Z., Vandvik, P. O., Sun, X., & Guyatt, G. H. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004827.pub3 · Cited by 258 · see citing works
Probiotics for treatment of Clostridium difficile-associated colitis in adults
Pillai, A. A., & Nelson, R. L. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004611.pub2 · Cited by 251 · see citing works
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis
Singh, S., Stroud, A., Holubar, S. D., Sandborn, W. J., & Pardi, D. S. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001176.pub3 · Cited by 250 · see citing works
Probiotics in the Management of Inflammatory Bowel Disease: A Systematic Review of Intervention Studies in Adult Patients
Jonkers, D., Penders, J., Masclee, A., & Pierik, M. (2012) · Drugs · doi:10.2165/11632710-000000000-00000 · Cited by 240 · see citing works
Systemic Immunity-Enhancing Effects in Healthy Subjects Following Dietary Consumption of the Lactic Acid BacteriumLactobacillus rhamnosusHN001
Sheih, Y.-H., Chiang, B., Wang, L.-H., Liao, C.-K., & Gill, H. S. (2001) · Journal of the American College of Nutrition · doi:10.1080/07315724.2001.10719027 · Cited by 237 · see citing works
Therapeutic Modulation of Microbiota-Host Metabolic Interactions
Holmes, E. C., Kinross, J. K., Gibson, G. R., Burcelin, R., Jia, W. P., Pettersson, S., & Nicholson, J. K. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004244 · Cited by 235 · see citing works
Elie Metchnikoff: Father of natural immunity
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Review article: probiotics for the treatment of irritable bowel syndrome – focus on lactic acid bacteria
Clarke, G. A., Cryan, J. F., Dinan, T. G., & Quigley, E. M. M. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2011.04965.x · Cited by 217 · see citing works
The Effect of a Multispecies Probiotic Mixture on the Symptoms and Fecal Microbiota in Diarrhea-dominant Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled Trial
Ki Cha, B., Mun Jung, S., Hwan Choi, C., Song, I.-D., Woong Lee, H., Joon Kim, H., Hyuk, J., Kyung Chang, S., Kim, K., Chung, W.-S., et al. (2012) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e31823712b1 · Cited by 216 · see citing works
Probiotics: what are they? What are their effects on gut physiology?
Fioramonti, J., Théodorou, V., & Bueno, L. P. (2003) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/s1521-6918(03)00075-1 · Cited by 212 · see citing works
Gut microbiota, probiotics, and vitamin D: Interrelated exposures influencing allergy, asthma, and obesity?
Ly, N. P., Litonjua, A. A., Gold, D. R., & Celedon, J. C. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.02.015 · Cited by 211 · see citing works
A randomized double-blind trial on perioperative administration of probiotics in colorectal cancer patients
Gianotti, L. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i2.167 · Cited by 209 · see citing works
Probiotics for induction of remission in Crohn's disease
Limketkai, B. N., Akobeng, A. K., Gordon, M. A., & Adepoju, A. A. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006634.pub3 · Cited by 205 · see citing works
Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics The GenBank accession number for the sequence reported in this paper is AY007251.
Holo, H., Jeknić, Z., Daeschel, M. A., Stevanović, S., & Nes, I. F. (2001) · Microbiology · doi:10.1099/00221287-147-3-643 · Cited by 203 · see citing works
Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment
Zakostelska, Z. J., Kverka, M., Kostovcikova, K., Rossmann, P., Mrázek, J., Kopečný, J., Hornová, M., Šrůtková, D., Hudcovic, T., Rídl, J., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027961 · Cited by 201 · see citing works
Probiotic Bacteria Influence the Composition and Function of the Intestinal Microbiota
O’Toole, P. W., & Cooney, J. C. (2008) · Interdisciplinary Perspectives on Infectious Diseases · doi:10.1155/2008/175285 · Cited by 201 · see citing works
The Prolongation Of Life...
Metchnikoff, É. (2012) · Cited by 200 · see citing works
Probiotics for induction of remission in ulcerative colitis
Mallon, P. T., McKay, D., Kirk, S. J., & Gardiner, K. R. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005573.pub2 · Cited by 197 · see citing works
Improved Detection of Bifidobacteria with Optimised 16S rRNA-Gene Based Pyrosequencing
Sim, K., Cox, M. J., Wopereis, H., Martı́n, R., Knol, J., Li, M., Cookson, W., Moffatt, M. F., & Kroll, J. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032543 · Cited by 196 · see citing works
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Effects of Long-term Consumption of a Fermented Infant Formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on Acute Diarrhea in Healthy Infants
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Probiotics for maintenance of remission in ulcerative colitis
Iheozor‐Ejiofor, Z., Kaur, L., Gordon, M. A., Baines, P. A., Sinopoulou, V., & Akobeng, A. K. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007443.pub3 · Cited by 193 · see citing works
Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing
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Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high‐risk infants
Ismail, I. H., Oppedisano, F., Joseph, S. J., Boyle, R. J., Licciardi, P. V., Robins-Browne, R. M., & Tang, M. L. K. (2012) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2012.01328.x · Cited by 189 · see citing works
Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections
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A protective effect of L actobacillus rhamnosus HN 001 against eczema in the first 2 years of life persists to age 4 years
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Intestinal microbiology in early life: specific prebiotics can have similar functionalities as human-milk oligosaccharides
Oozeer, R., van Limpt, K., Ludwig, T., Amor, K. B., Martı́n, R., Wind, R. D., Boehm, G., & Knol, J. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.038893 · Cited by 177 · see citing works
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Synbiotics prevent asthma-like symptoms in infants with atopic dermatitis
van der Aa, L. B., van Aalderen, W. M. C., Heymans, H. S. A., Henk Sillevis Smitt, J., Nauta, A. J., Knippels, L. M. J., Ben Amor, K., Sprikkelman, A. B., & the Synbad Study Group (2011) · Allergy · doi:10.1111/j.1398-9995.2010.02416.x · Cited by 172 · see citing works
Taxonomy and Ecology of Bifidobacteria
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Bacterial vitamin B2, B11 and B12 overproduction: An overview
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Pattern recognition receptors—Molecular orchestrators of inflammation in inflammatory bowel disease
Walsh, D. P., McCarthy, J., O’Driscoll, C. M., & Melgar, S. (2012) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2012.09.003 · Cited by 161 · see citing works
Effect of a new synbiotic mixture on atopic dermatitis in infants: a randomized‐controlled trial
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Early Administration of Probiotics Alters Bacterial Colonization and Limits Diet-Induced Gut Dysfunction and Severity of Necrotizing Enterocolitis in Preterm Pigs3
Siggers, R. H., Siggers, J., Boyé, M., Thymann, T., Mølbak, L., Leser, T. D., Jensen, B. B., & Sangild, P. T. (2008) · Journal of Nutrition · doi:10.1093/jn/138.8.1437 · Cited by 156 · see citing works
Characterization of the SpaCBA Pilus Fibers in the Probiotic Lactobacillus rhamnosus GG
Reunanen, J., von Ossowski, I., Hendrickx, A. P. A., Palva, A., & de Vos, W. M. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.07047-11 · Cited by 155 · see citing works
Enzymatic synthesis of galacto-oligosaccharides and other lactose derivatives (hetero-oligosaccharides) from lactose
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A Gastroenterologist's Guide to Probiotics
Ciorba, M. A. (2012) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2012.03.024 · Cited by 150 · see citing works
Quantification of Folic Acid in Human Feces After Administration of Bifidobacterium Probiotic Strains
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Diet, the human gut microbiota, and IBD
Wu, G. D., Bushmanc, F. D., & Lewis, J. D. (2013) · Anaerobe · doi:10.1016/j.anaerobe.2013.03.011 · Cited by 140 · see citing works
Intestinal dysbiosis in inflammatory bowel disease
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Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea
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Dietary Modulation of Gut Functional Ecology Studied by Fecal Metabonomics
Martin, F., Sprenger, N., Montoliu, I., Rezzi, S., Kochhar, S., & Nicholson, J. K. (2010) · Journal of Proteome Research · doi:10.1021/pr100554m · Cited by 136 · see citing works
Prebiotics in infants for prevention of allergic disease and food hypersensitivity
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Probiotics for maintenance of remission in ulcerative colitis
Naidoo, K., Gordon, M. A., Fagbemi, A. O., Thomas, A. G., & Akobeng, A. K. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007443.pub2 · Cited by 136 · see citing works
Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Prevention and Management of Allergic Diseases by Probiotics1–3
Kalliomäki, M. A., Antoine, J., Herz, U., Rijkers, G. T., Wells, J. M., & Mercenier, A. (2010) · Journal of Nutrition · doi:10.3945/jn.109.113761 · Cited by 132 · see citing works
Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer
Appleyard, C. B., Cruz, M. L., Isidro, A., Arthur, J. C., Jobin, C., & Simone, C. D. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00167.2011 · Cited by 131 · see citing works
Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases
Gentschew, L., & Ferguson, L. R. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100630 · Cited by 130 · see citing works
Probiotic Therapy as a Novel Approach for Allergic Disease
Toh, Z. Q., Anzela, A., Tang, M. L. K., & Licciardi, P. V. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2012.00171 · Cited by 129 · see citing works
Impact of Bifidobacterium animalis subsp. lactis BB-12 and, Lactobacillus acidophilus LA-5-containing yoghurt, on fecal bacterial counts of healthy adults
Savard, P., Lamarche, B., Paradis, M., Thiboutot, H., Laurin, E. L., & Roy, D. (2011) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.12.026 · Cited by 128 · see citing works
Lactobacillus casei Abundance Is Associated with Profound Shifts in the Infant Gut Microbiome
Cox, M. J., Huang, Y. J., Fujimura, K. E., Liu, J. T., McKean, M., Boushey, H. A., Segal, M. R., Brodie, E., Cabana, M. D., & Lynch, S. V. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008745 · Cited by 126 · see citing works
Probiotic Lactobacillus acidophilus enhances the immunogenicity of an oral rotavirus vaccine in gnotobiotic pigs
Zhang, W., Azevedo, M. S. P., Wen, K., et al. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.04.070 · Cited by 125 · see citing works
Host-microbiota interactions in inflammatory bowel disease
Elson, C. O., & Cong, Y. (2012) · Gut Microbes · doi:10.4161/gmic.20228 · Cited by 124 · see citing works
Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis
Holubar, S. D., Cima, R. R., Sandborn, W. J., et al. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001176.pub2 · Cited by 121 · see citing works
Probiotics and prebiotics in the management of irritable bowel syndrome: a review of recent clinical trials and systematic reviews
Whelan, K. (2011) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e32834b8082 · Cited by 120 · see citing works
Fermented milk supplemented with probiotics and prebiotics can effectively alter the intestinal microbiota and immunity of host animals
Wang, S., Zhu, H., Lu, C., Kang, Z., Luo, Y., Feng, L., & Lu, X. (2012) · Journal of Dairy Science · doi:10.3168/jds.2012-5426 · Cited by 115 · see citing works
Initial Dietary and Microbiological Environments Deviate in Normal‐weight Compared to Overweight Children at 10 Years of Age
Luoto, R., Kalliomäki, M. A., Laitinen, K., Delzenne, N. M., Cani, P. D., Salminen, S., & Isolauri, E. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181f3457f · Cited by 110 · see citing works
The quest for probiotic effector molecules—Unraveling strain specificity at the molecular level
Lee, I.-C., Tomita, S., Kleerebezem, M., & Bron, P. A. (2012) · Pharmacological Research · doi:10.1016/j.phrs.2012.09.010 · Cited by 109 · see citing works
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Bifidobacterium lactis Bb12 Enhances Intestinal Antibody Response in Formula‐Fed Infants
Holscher, H. D., Czerkies, L. A., Cekola, P., Litov, R. E., Benbow, M., Santema, S., Alexander, D. D., Pérez, V., Sun, S. S., Saavedra, J. M., et al. (2012) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607111430817 · Cited by 108 · see citing works
Probiotics for treating persistent diarrhoea in children
Aponte, G. B., Mancilla, C. A. B., Carreazo, N. Y., & Galarza, R. A. R. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007401.pub3 · Cited by 108 · see citing works
454 Pyrosequencing Analysis on Faecal Samples from a Randomized DBPC Trial of Colicky Infants Treated with Lactobacillus reuteri DSM 17938
Roos, S., Dicksved, J., Tarasco, V., Locatelli, E., Ricceri, F., Grandin, U., & Savino, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056710 · Cited by 99 · see citing works
The Intestinal Environment in Health and Disease – Recent Insights on the Potential of Intestinal Bacteria to Influence Human Health
Possemiers, S., Grootaert, C., Vermeiren, J., Gross, G., Marzorati, M., Verstraete, W., & de Wiele, T. V. (2009) · Current Pharmaceutical Design · doi:10.2174/138161209788489159 · Cited by 91 · see citing works
Probiotics for induction of remission in Crohn's disease
Butterworth, A. D., Thomas, A. G., & Akobeng, A. K. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006634.pub2 · Cited by 91 · see citing works
Intestinal Microbiota and Obesity
Blaut, M., & Klaus, S. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-24716-3_11 · Cited by 89 · see citing works
A probiotics-containing biscuit modulates the intestinal microbiota in the elderly
Rampelli, S., Candela, M., Severgnini, M., Biagi, E., Turroni, S., Roselli, M., Carnevali, P., Donini, L. M., & Brigidi, P. (2012) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0372-x · Cited by 88 · see citing works
Glycolipid receptors for verotoxin and Helicobacter pylori: role in pathology
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Probiotics in Food Safety and Human Health
Goktepe, I., Juneja, V. K., & Ahmedna, M. (2005) · CRC Press eBooks · doi:10.1201/9781420027570 · Cited by 84 · see citing works
Proton transfer reaction time‐of‐flight mass spectrometry monitoring of the evolution of volatile compounds during lactic acid fermentation of milk
Soukoulis, C., Aprea, E., Franco Biasioli, A., Cappellin, L., Schuhfried, E., Märk, T. D., & Gasperi, F. (2010) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.4617 · Cited by 77 · see citing works
The potential for probiotic manipulation of the gastrointestinal microbiome
Rauch, M., & Lynch, S. V. (2011) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2011.11.004 · Cited by 76 · see citing works
Gut matters: Microbe-host interactions in allergic diseases
Hörmannsperger, G., Clavel, T., & Haller, D. (2012) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.12.993 · Cited by 74 · see citing works
Molecular mechanisms of probiotic action: a proteomic perspective
Siciliano, R. A., & Mazzeo, M. F. (2012) · Current Opinion in Microbiology · doi:10.1016/j.mib.2012.03.006 · Cited by 72 · see citing works
Intestinal microbiota and obesity
Zuziak, P., Ilnicka, N., Abod, L., Matyja, D., & Sadlik, M. (2022) · Journal of Education Health and Sport · doi:10.12775/jehs.2023.13.02.020 · Cited by 71 · see citing works
Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infection
Schunter, M., Chu, H., Hayes, T. L., McConnell, D. H., Crawford, S. S., Luciw, P. A., Bengmark, S., Asmuth, D. M., Brown, J., Bevins, C. L., et al. (2012) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-12-84 · Cited by 70 · see citing works
Pediatric Applications of Inulin and Oligofructose
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Streptococcus thermophilus Is Able To Produce a β-Galactosidase Active during Its Transit in the Digestive Tract of Germ-Free Mice
Drouault, S., Anba‐Mondoloni, J., & Corthier, G. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.2.938-941.2002 · Cited by 67 · see citing works
Probiotic properties of folate producing Streptococcus thermophilus strains
Iyer, R., Tomar, S. K., Kapila, S., Mani, J., & Singh, R. (2009) · Food Research International · doi:10.1016/j.foodres.2009.09.011 · Cited by 67 · see citing works
Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching
Bron, P. A., Tomita, S., van Swam, I. I., Remus, D. M., Meijerink, M., Wels, M., Okada, S., Wells, J. M., & Kleerebezem, M. (2012) · Microbial Cell Factories · doi:10.1186/1475-2859-11-123 · Cited by 67 · see citing works
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Vaccine adjuvant properties of probiotic bacteria.
Licciardi, P. V., & Tang, M. L. K. (2011) · PubMed · Cited by 58 · see citing works
Fecal microbiota diversity in survivors of adolescent/young adult Hodgkin lymphoma: a study of twins
Cozen, W., Yu, G., Gail, M. H., Ridaura, V. K., Nathwani, B. N., Hwang, A. E., Hamilton, A. S., Mack, T. M., Gordon, J. I., & Goedert, J. J. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.60 · Cited by 58 · see citing works
Effect of a Fermented Formula on Thymus Size and Stool pH in Healthy Term Infants
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Strain‐specific immunomodulatory effects of Lactobacillus plantarum strains on birch‐pollen‐allergic subjects out of season
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Effects of Lactobacillus GG treatment during pregnancy on the development of fetal antigen‐specific immune responses
Boyle, R. J., Mah, L. ‐., Chen, A., Kivivuori, S., Robins-Browne, R. M., & Tang, M. L. K. (2008) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2008.03100.x · Cited by 52 · see citing works
The Role of Colonic Microbiota in Lactose Intolerance
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Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases
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Lactococcus lactisas an adjuvant and delivery vehicle of antigens against pneumococcal respiratory infections
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Probiotics in the prevention and treatment of allergic disease
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An intimate tête-à-tête — How probiotic lactobacilli communicate with the host
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Probiotics for treating persistent diarrhoea in children
Aponte, G. B., Mancilla, C. A. B., Carreazo, N. Y., & Galarza, R. A. R. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007401.pub2 · Cited by 42 · see citing works
Probiotics in Food Safety and Human Health
Marshall, V. M. (2007) · International Journal of Dairy Technology · doi:10.1111/j.1471-0307.2007.00324.x · Cited by 36 · see citing works
Probiotics promote endocytic allergen degradation in gut epithelial cells
Song, C., Liu, Z., Huang, S., Zheng, P., & Yang, P. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.08.051 · Cited by 34 · see citing works
Nutritional influences on the gut microbiota and the consequences for gastrointestinal health
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Upregulation of Intestinal Mucin Expression by the Probiotic Bacterium E. coli Nissle 1917
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Bifidobacterium bifidum NCC 453 Promotes Tolerance Induction in Murine Models of Sublingual Immunotherapy
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Health benefits of fermented foods
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Synbiotics: a New Route of Self-production and Applications to Human and Animal Health
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Shim, S. B. (2005) · doi:10.18174/121655 · Cited by 31 · see citing works

Authors: Ceapa, C., Wopereis, H., Rezaïki, L., Kleerebezem, M., Knol, J., & Oozeer, R.
Affiliations: Wageningen University & Research (NL)
ORCID: Wopereis, Harm
Kleerebezem, Michiel
Knol, Jan
Oozeer, Raish
Venue: Best Practice & Research Clinical Gastroenterology
Publisher: Elsevier BV
Published: 2013-02
Volume: 27
Issue: 1
Pages: 139-155
ISSN: 1521-6918 (ISSN-L)
DOI: 10.1016/j.bpg.2013.04.004
OpenAlex: W2114284685
Cited by: 98
References: 187
Citations by year: 2026: 1 · 2025: 3 · 2024: 1 · 2023: 9 · 2022: 7 · 2021: 10 · 2020: 16 · 2019: 5 · 2018: 6 · 2017: 12 · 2016: 10 · 2015: 6 · 2014: 11 · 2013: 1
FWCI: 1.25
Type: journal article
Language: en
Open access: green
research.wur.nl
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Best Practice & Research Clinical Gastroenterology (publishedVersion)
PubMed (publishedVersion)
Socio-Environmental Systems Modeling (acceptedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Funders: Marie Curie International Training Mobility Network (21553-2)
Danone Research – Centre for Specialized Nutrition
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords: gut microbiota, fermented milk, prebiotics, probiotics, synbiotics, dysbiosis, eubiosis, host-microbe crosstalk, inflammatory bowel disease, metabolic syndrome, allergic diseases, health benefits
MeSH terms: Health Status, Humans, Nutritional Physiological Phenomena, Probiotics, Gastrointestinal Tract, Cultured Milk Products, Host-Pathogen Interactions, Metagenome, Prebiotics

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Influence of fermented milk products, prebiotics and probiotics on microbiota composition and health

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