Epilepsy and autism spectrum disorders: are there common developmental mechanisms?

Function and regulation of CREB family transcription factors in the nervous system

Lonze, B. E., & Ginty, D. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00828-0 · Cited by 2,127 · see citing works

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

Study, P. A. R. I. S., Jamain, S., Quach, H., Betancur, C., Råstam, M., Colineaux, C., Gillberg, I. C., Soderstrom, H., Giros, B., Leboyer, M., et al. (2003) · Nature Genetics · doi:10.1038/ng1136 · Cited by 1,851 · see citing works

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

Chahrour, M., Jung, S. Y., Shaw, C., Zhou, X., Wong, S. T. C., Qin, J., & Zoghbi, H. Y. (2008) · Science · doi:10.1126/science.1153252 · Cited by 1,823 · see citing works

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Durand, C. M., Betancur, C., Boeckers, T. M., Bockmann, J., Chaste, P., Fauchereau, F., Nygren, G., Rastam, M., Gillberg, I. C., Anckarsäter, H., et al. (2007) · Nature Genetics · doi:10.1038/ng1933 · Cited by 1,602 · see citing works

The mGluR theory of fragile X mental retardation

Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.04.009 · Cited by 1,580 · see citing works

The Story of Rett Syndrome: From Clinic to Neurobiology

Chahrour, M., & Zoghbi, H. Y. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.001 · Cited by 1,265 · see citing works

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

Chen, W. G., Chang, Q., Lin, Y., Meissner, A., West, A. E., Griffith, E. C., Jaenisch, R., & Greenberg, M. E. (2003) · Science · doi:10.1126/science.1086446 · Cited by 1,232 · see citing works

Requirement for Hippocampal CA3 NMDA Receptors in Associative Memory Recall

Nakazawa, K., Quirk, M. C., Chitwood, R. A., Watanabe, M., Yeckel, M. F., Sun, L. D., Kato, A., Carr, C. A., Johnston, D., Wilson, M. A., et al. (2002) · Science · doi:10.1126/science.1071795 · Cited by 1,090 · see citing works

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

Bassell, G. J., & Warren, S. T. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.004 · Cited by 1,051 · see citing works

Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5401 · Cited by 1,046 · see citing works

A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice

Tabuchi, K., Blundell, J., Etherton, M. R., Hammer, R. E., Liu, X., Powell, C. M., & Südhof, T. C. (2007) · Science · doi:10.1126/science.1146221 · Cited by 997 · see citing works

Glutamate receptor function in learning and memory

Riedel, G. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00272-3 · Cited by 964 · see citing works

The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses

Zalfa, F., Giorgi, M., Primerano, B., Moro, A., Di Penta, A., Reis, S., Oostra, B., & Bagni, C. (2003) · Cell · doi:10.1016/s0092-8674(03)00079-5 · Cited by 676 · see citing works

Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett Syndrome

Dani, V. S., Chang, Q., Maffei, A., Turrigiano, G. G., Jaenisch, R., & Nelson, S. B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506071102 · Cited by 639 · see citing works

Dendritic Spine Structural Anomalies in Fragile-X Mental Retardation Syndrome

Irwin, S. A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.10.1038 · Cited by 626 · see citing works

Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2

Chubykin, A. A., Atasoy, D., Etherton, M. R., Brose, N., Kavalali, E. T., Gibson, J. R., & Südhof, T. C. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.029 · Cited by 594 · see citing works

Evidence that fragile X mental retardation protein is a negative regulator of translation

Laggerbauer, B. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.4.329 · Cited by 571 · see citing works

Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes.

Feng, Y., Gutekunst, C.-A., Eberhart, D. E., Yi, H., Warren, S. T., & Hersch, S. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01539.1997 · Cited by 532 · see citing works

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

Gibson, J. R., Bartley, A. F., Hays, S. A., & Huber, K. M. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90752.2008 · Cited by 529 · see citing works

Analysis of GABA A Receptor Function and Dissection of the Pharmacology of Benzodiazepines and General Anesthetics Through Mouse Genetics

Rudolph, U., & Möhler, H. (2004) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121429 · Cited by 518 · see citing works

Specific GABA _A Circuits for Visual Cortical Plasticity

Fagiolini, M., Fritschy, J.-M., Löw, K., Möhler, H., Rudolph, U., & Hensch, T. K. (2004) · Science · doi:10.1126/science.1091032 · Cited by 471 · see citing works

The fragile X mental retardation protein inhibits translation via interacting with mRNA

Li, Z. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.11.2276 · Cited by 448 · see citing works

Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome

Muddashetty, R. S., Kelić, S., Gross, C., Xu, M., & Bassell, G. J. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0937-07.2007 · Cited by 421 · see citing works

The Pathophysiology of Fragile X Syndrome

Penagarikano, O., Mulle, J. G., & Warren, S. T. (2007) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.8.080706.092249 · Cited by 420 · see citing works

Metabotropic Glutamate Receptor Activation Regulates Fragile X Mental Retardation Protein and <i>Fmr1</i> mRNA Localization Differentially in Dendrites and at Synapses

Antar, L. N., Afroz, R., Dictenberg, J. B., Carroll, R. C., & Bassell, G. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0099-04.2004 · Cited by 360 · see citing works

A developmental switch in the signaling cascades for LTP induction

Yasuda, H., Barth, A. L., Stellwagen, D., & Malenka, R. C. (2003) · Nature Neuroscience · doi:10.1038/nn985 · Cited by 325 · see citing works

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development

Lu, R., Wang, H., Liang, Z., Ku, L., O'Donnell, W. T., Li, W., Warren, S. T., & Feng, Y. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404995101 · Cited by 322 · see citing works

Decreased expression of the GABAA receptor in fragile X syndrome

D'Hulst, C., De Geest, N., Reeve, S. P., Van Dam, D., De Deyn, P. P., Hassan, B. A., & Kooy, R. F. (2006) · Brain Research · doi:10.1016/j.brainres.2006.08.115 · Cited by 318 · see citing works

Temporal lobe epilepsy after experimental prolonged febrile seizures: prospective analysis

Dubé, C. M., Richichi, C., Bender, R. A., Chung, G., Litt, B., & Baram, T. Z. (2006) · Brain · doi:10.1093/brain/awl018 · Cited by 283 · see citing works

Developmental Febrile Seizures Modulate Hippocampal Gene Expression of Hyperpolarization-Activated Channels in an Isoform- and Cell-Specific Manner

Brewster, A. L., Bender, R. A., Chen, Y., Dubé, C. M., Eghbal-Ahmadi, M., & Baram, T. Z. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-11-04591.2002 · Cited by 270 · see citing works

Decreased Glutamate Receptor 2 Expression and Enhanced Epileptogenesis in Immature Rat Hippocampus after Perinatal Hypoxia-Induced Seizures

Sanchez, R. M., Koh, S., Río, C., Wang, C., Lamperti, E. D., Sharma, D., Corfas, G., & Jensen, F. E. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08154.2001 · Cited by 237 · see citing works

Decreased GABAA receptor expression in the seizure-prone fragile X mouse

Idrissi, A. E., Ding, X., Scalia, J., Trenkner, E., Brown, W. T., & Dobkin, C. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.11.087 · Cited by 210 · see citing works

Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females

Marsh, E. D., Fulp, C. T., Gomez, E., Nasrallah, I. M., Minarcik, J. C., Sudi, J., Christian, S. L., Mancini, G. M. S., Labosky, P. A., Dobyns, W. B., et al. (2009) · Brain · doi:10.1093/brain/awp107 · Cited by 209 · see citing works

Spine Loss and Other Persistent Alterations of Hippocampal Pyramidal Cell Dendrites in a Model of Early-Onset Epilepsy

Jiang, M., Lee, C. L., Smith, K. L., & Swann, J. W. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-20-08356.1998 · Cited by 207 · see citing works

Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model

Wong, M. L., Ess, K. C., Uhlmann, E. J., Jansen, L. A., Li, W., Crino, P. B., Mennerick, S. J., Yamada, K. A., & Gutmann, D. H. (2003) · Annals of Neurology · doi:10.1002/ana.10648 · Cited by 199 · see citing works

Prolonged Epileptiform Discharges Induced by Altered Group I Metabotropic Glutamate Receptor-Mediated Synaptic Responses in Hippocampal Slices of a Fragile X Mouse Model

Chuang, S.-C., Zhao, W., Bauchwitz, R., Yan, Q., Bianchi, R., & Wong, R. K. S. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1777-05.2005 · Cited by 190 · see citing works

Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and Beyond

Grossman, A. W., Aldridge, G. M., Weiler, I. J., & Greenough, W. T. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1790-06.2006 · Cited by 178 · see citing works

Quantitative neuropathological changes in presymptomatic Huntington's disease

Gómez‐Tortosa, E., MacDonald, M. E., Friend, J. C., Taylor, S. A., Weiler, L., Cupples, L. A., Srinidhi, J., Gusella, J. F., Bird, E. D., Vonsattel, J., et al. (2001) · Annals of Neurology · doi:10.1002/1531-8249(200101)49:1 · Cited by 170 · see citing works

Expression profiling suggests underexpression of the GABAA receptor subunit δ in the fragile X knockout mouse model

Gantois, I., Vandesompele, J., Speleman, F., Reyniers, E., D’Hooge, R., Severijnen, L.-A. W. F. M., Willemsen, R., Tassone, F., & Kooy, R. F. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.07.017 · Cited by 166 · see citing works

Modulation of dendritic differentiation by corticotropin-releasing factor in the developing hippocampus

Chen, Y., Bender, R. A., Brunson, K. L., Pomper, J. K., Grigoriadis, D. E., Wurst, W., & Baram, T. Z. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403975101 · Cited by 166 · see citing works

Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS)

D’Hulst, C., Heulens, I., Brouwer, J. R., Willemsen, R., Geest, N. D., Reeve, S. P., Deyn, P. P. D., Hassan, B. A., & Kooy, R. F. (2008) · Brain Research · doi:10.1016/j.brainres.2008.11.075 · Cited by 164 · see citing works

Convulsing toward the pathophysiology of autism

Tuchman, R., Moshé, S. L., & Rapin, I. (2009) · Brain and Development · doi:10.1016/j.braindev.2008.09.009 · Cited by 142 · see citing works

Febrile seizures impair memory and cAMP response‐element binding protein activation

Chang, Y., Huang, A., Kuo, Y., Wang, S., Chang, Y., & Huang, C. (2003) · Annals of Neurology · doi:10.1002/ana.10789 · Cited by 132 · see citing works

Restoration of spatial working memory by genetic rescue of GluR-A–deficient mice

Schmitt, W. B., Sprengel, R., Mack, V., Draft, R. W., SEEBURG, P. H., Deacon, R. M. J., Rawlins, J. N. P., & Bannerman, D. M. (2005) · Nature Neuroscience · doi:10.1038/nn1412 · Cited by 131 · see citing works

Formation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures

Brewster, A. L., Bernard, J. A., Gall, C. M., & Baram, T. Z. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.12.015 · Cited by 130 · see citing works

Intact Long-Term Potentiation but Reduced Connectivity between Neocortical Layer 5 Pyramidal Neurons in a Mouse Model of Rett Syndrome

Dani, V. S., & Nelson, S. B. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1019-09.2009 · Cited by 121 · see citing works

Long‐term alterations in glutamate receptor and transporter expression following early‐life seizures are associated with increased seizure susceptibility

Zhang, G., Raol, Y. S. H., Hsu, F., & Brooks‐Kayal, A. R. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02124.x · Cited by 109 · see citing works

Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital

Sutula, T. P., Cavazos, J. E., & Golarai, G. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-11-04173.1992 · Cited by 106 · see citing works

Benzodiazepines block long-term potentiation in slices of hippocampus and piriform cortex

del Cerro, S., Jung, M., & Lynch, G. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90071-9 · Cited by 106 · see citing works

Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: Implications for autism and epilepsy

Gant, J. C., Thibault, O., Blalock, E. M., Yang, J., Bachstetter, A. D., Kotick, J. D., Schauwecker, P. E., Hauser, K. F., Smith, G. M., Mervis, R., et al. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01725.x · Cited by 106 · see citing works

Retrospective and prospective persistent activity induced by Hebbian learning in a recurrent cortical network

Mongillo, G., Amit, D. J., & Brunel, N. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02908.x · Cited by 100 · see citing works

Origins of Epilepsy in Fragile X Syndrome

Hagerman, P. J., & Stafstrom, C. E. (2009) · Epiliepsy currents/Epilepsy currents · doi:10.1111/j.1535-7511.2009.01309.x · Cited by 94 · see citing works

How do the many etiologies of West syndrome lead to excitability and seizures? The corticotropin releasing hormone excess hypothesis

Brunson, K. L., Eghbal-Ahmadi, M., & Baram, T. Z. (2001) · Brain and Development · doi:10.1016/s0387-7604(01)00312-6 · Cited by 89 · see citing works

Developmental Expression of GABAA Receptor Subunit mRNAs in Individual Hippocampal Neurons In Vitro and In Vivo

Brooks‐Kayal, A. R., Jin, H., Price, M., & Dichter, M. A. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.70031017.x · Cited by 82 · see citing works

Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy

Lee, C. L., Hannay, H. J., Hrachovy, R. A., Rashid, S., Antalffy, B. A., & Swann, J. W. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00327-x · Cited by 80 · see citing works

Modulation of Long-term Potentiation in CA1 Region of Mouse Hippocampal Brain Slices by GABAA Receptor Benzodiazepine Site Ligands

Seabrook, G. R., Easter, A., Dawson, G. R., & Bowery, B. J. (1997) · Neuropharmacology · doi:10.1016/s0028-3908(97)00040-3 · Cited by 75 · see citing works

Evaporation and deposition of alkyl-capped silicon nanocrystals in ultrahigh vacuum

Chao, Y., Šiller, L., Krishnamurthy, S., Coxon, P. R., Bangert, U., Gass, M. H., Kjeldgaard, L., Patole, S. N., Lie, L. H., O'Farrell, N., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.224 · Cited by 74 · see citing works

Group I Metabotropic Glutamate Receptors Elicit Epileptiform Discharges in the Hippocampus through PLCβ1 Signaling

Chuang, S.-C., Bianchi, R., Kim, D., Shin, H., & Wong, R. K. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06387.2001 · Cited by 73 · see citing works

Group I mGluR Activation Turns on a Voltage-Gated Inward Current in Hippocampal Pyramidal Cells

Chuang, S.-C., Bianchi, R., & Wong, R. K. S. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.5.2844 · Cited by 72 · see citing works

Involvement of AMPA Receptor GluR2 Subunits in Stimulus-Reward Learning: Evidence from Glutamate Receptorgria2Knock-Out Mice

Mead, A. N., & Stephens, D. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-29-09500.2003 · Cited by 68 · see citing works

Cellular Plasticity for Group I mGluR-Mediated Epileptogenesis

Bianchi, R., Chuang, S.-C., Zhao, W., Young, S. R., & Wong, R. K. S. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5447-08.2009 · Cited by 67 · see citing works

Increased GABAA‐Receptor α1‐Subunit Expression in Hippocampal Dentate Gyrus after Early‐life Status Epilepticus

Raol, Y. H., Zhang, G., Lund, I. V., Porter, B. E., Maronski, M., & Brooks‐Kayal, A. R. (2006) · Epilepsia · doi:10.1111/j.1528-1167.2006.00640.x · Cited by 62 · see citing works

Comparison the cognitive effect of anti-epileptic drugs in seizure-free children with epilepsy before and after drug withdrawal

Chen, Y.-J., Chow, J. C., & Lee, I. (2001) · Epilepsy Research · doi:10.1016/s0920-1211(00)00204-7 · Cited by 49 · see citing works

Association of the neuropilin‐2 (NRP2) gene polymorphisms with autism in Chinese Han population

Wu, S., Yue, W., Jia, M., Ruan, Y., Lu, T., Gong, X., Mei, S., Liu, J., Yang, X., & Zhang, D. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30495 · Cited by 46 · see citing works

The effects of seizures on the connectivity and circuitry of the developing brain

Swann, J. W. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20018 · Cited by 39 · see citing works

Hippocampal neurogenesis is not enhanced by lifelong reduction of glucocorticoid levels

Brunson, K. L., Baram, T. Z., & Bender, R. A. (2005) · Hippocampus · doi:10.1002/hipo.20074 · Cited by 34 · see citing works

Untitled work

Cann, S. A. H., Netten, J. P. V., & Netten, C. V. (2000) · Pure Amsterdam UMC · doi:10.1002/1531-8249(200003)47:3

Disentangling the heterogeneity of autism spectrum disorder through genetic findings

Jeste, S. S., & Geschwind, D. H. (2014) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.278 · Cited by 644 · see citing works

Common Mechanisms of Excitatory and Inhibitory Imbalance in Schizophrenia and Autism Spectrum Disorders

Gao, R., & Penzes, P. (2015) · Current Molecular Medicine · doi:10.2174/1566524015666150303003028 · Cited by 516 · see citing works

Alterations of GABAergic Signaling in Autism Spectrum Disorders

Pizzarelli, R., & Cherubini, E. (2011) · Neural Plasticity · doi:10.1155/2011/297153 · Cited by 323 · see citing works

Exome sequencing reveals new causal mutations in children with epileptic encephalopathies

Veeramah, K. R., Johnstone, L. M., Karafet, T. M., Wolf, D., Sprissler, R. S., Salogiannis, J., Barth‐Maron, A., Greenberg, M. E., Stuhlmann, T., Weinert, S., et al. (2013) · Epilepsia · doi:10.1111/epi.12201 · Cited by 294 · see citing works

Early diagnosis of autism and impact on prognosis: a narrative review

Fernell, E., Eriksson, �., & Gillberg, C. (2013) · Clinical Epidemiology · doi:10.2147/clep.s41714 · Cited by 223 · see citing works

Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives

Deidda, G., Bozarth, I. F., & Cancedda, L. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00119 · Cited by 192 · see citing works

Genetics and Function of Neocortical GABAergic Interneurons in Neurodevelopmental Disorders

Rossignol, E. (2011) · Neural Plasticity · doi:10.1155/2011/649325 · Cited by 183 · see citing works

The Interaction between Early Life Epilepsy and Autistic-Like Behavioral Consequences: A Role for the Mammalian Target of Rapamycin (mTOR) Pathway

Talos, D. M., Sun, H., Zhou, X., Fitzgerald, E. C., Jackson, M. C., Klein, P., Lan, V. J., Joseph, A., & Jensen, F. E. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035885 · Cited by 182 · see citing works

Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops

Mullins, C., Fishell, G., & Tsien, R. W. (2016) · Neuron · doi:10.1016/j.neuron.2016.02.017 · Cited by 167 · see citing works

Autism spectrum disorder and epilepsy: Disorders with a shared biology

Lee, B. H., Smith, T., & Paciorkowski, A. R. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.03.017 · Cited by 167 · see citing works

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

Lionel, A. C., Vaags, A. K., Sato, D., Gazzellone, M. J., Mitchell, E. B., Chen, H. Y., Costain, G., Walker, S., Egger, G., Thiruvahindrapuram, B., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt056 · Cited by 162 · see citing works

Prevalence and risk factors for autism spectrum disorder in epilepsy: A systematic review and meta-analysis

Strasser, L., Downes, M., Kung, J., Cross, J. H., & De Haan, M. (2018) · Developmental Medicine &amp; Child Neurology · doi:10.1111/dmcn.13598 · Cited by 148 · see citing works

Autism Spectrum Disorder and Epilepsy

Jeste, S., & Tuchman, R. F. (2015) · Journal of Child Neurology · doi:10.1177/0883073815601501 · Cited by 147 · see citing works

Epilepsy and autism: Is there a special relationship?

Berg, A. T., & Plioplys, S. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.01.015 · Cited by 144 · see citing works

Temporal Lobe Epilepsy and Psychiatric Comorbidity

Vinti, V., Dell’Isola, G. B., Tascini, G., Mencaroni, E., Cara, G. D., Striano, P., & Verrotti, A. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.775781 · Cited by 143 · see citing works

Association of Psychiatric and Neurologic Comorbidity With Mortality Among Persons With Autism Spectrum Disorder in a Danish Population

Schendel, D., Overgaard, M. T., Christensen, J., Hjort, L., Jørgensen, M., Vestergaard, M., & Parner, E. T. (2016) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2015.3935 · Cited by 135 · see citing works

Epilepsy and Autism: Neurodevelopmental Perspective

Tuchman, R. F., & Cuccaro, M. L. (2011) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-011-0195-x · Cited by 131 · see citing works

Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia

Merner, N. D., Chandler, M. R., Bourassa, C. V., Liang, B., Khanna, A. R., Dion, P. A., Rouleau, G. A., & Kahle, K. T. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00386 · Cited by 128 · see citing works

Autism, epilepsy, and synaptopathies: a not rare association

Keller, R., Basta, R., Salerno, L., & Elia, M. (2017) · Neurological Sciences · doi:10.1007/s10072-017-2974-x · Cited by 124 · see citing works

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

Spooren, W., Lindemann, L., Ghosh, A., & Santarelli, L. (2012) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2012.09.004 · Cited by 119 · see citing works

In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders

Pantazopoulos, H., & Berretta, S. (2015) · Neural Plasticity · doi:10.1155/2016/9847696 · Cited by 118 · see citing works

The neurology of autism spectrum disorders

Jeste, S. (2011) · Current Opinion in Neurology · doi:10.1097/wco.0b013e3283446450 · Cited by 128 · see citing works

Autism in Dravet syndrome: Prevalence, features, and relationship to the clinical characteristics of epilepsy and mental retardation

Li, B.-M., Liu, X., Yi, Y., Deng, Y., Su, T., Zou, X., & Liao, W. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.04.060 · Cited by 116 · see citing works

Exome sequencing in multiplex autism families suggests a major role for heterozygous truncating mutations

Toma, C., Torrico, B., Hervás, A., Valdés-Mas, R., Tristán-Noguero, A., Padillo, V, Maristany, M., Salgado, M., Arenas, C., Puente, X. S., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.106 · Cited by 114 · see citing works

Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder

Chonchaiya, W., Au, J., Schneider, A., Hessl, D., Harris, S. W., Laird, M., Mu, Y., Tassone, F., Nguyen, D. V., & Hagerman, R. J. (2012) · Human Genetics · doi:10.1007/s00439-011-1106-6 · Cited by 109 · see citing works

Deregulated mTOR-mediated translation in intellectual disability.

Troca-Marín, J. A., Alves-Sampaio, A., & Montesinos, M. (2012) · Progress in neurobiology · doi:10.1016/j.pneurobio.2012.01.005 · Cited by 97 · see citing works

Synaptic clustering differences due to different GABRB3 mutations cause variable epilepsy syndromes

Shi, Y., Zhang, Q., Cai, K., Poliquin, S., Shen, W., Winters, N. D., Yi, Y., Wang, J., Hu, N., Macdonald, R. L., et al. (2019) · Brain · doi:10.1093/brain/awz250 · Cited by 92 · see citing works

Neural Cell Adhesion Molecule NrCAM Regulates Semaphorin 3F-Induced Dendritic Spine Remodeling

Demyanenko, G. P., Mohan, V., Zhang, X., Brennaman, L. H., Dharbal, K. E. S., Tran, T. S., Manis, P. B., & Maness, P. F. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1774-14.2014 · Cited by 92 · see citing works

Emerging roles of Na+/H+ exchangers in epilepsy and developmental brain disorders

Zhao, H., Carney, K. E., Falgoust, L., Pan, J. W., Sun, D., & Zhang, Z. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.02.002 · Cited by 87 · see citing works

FMR1 premutation and full mutation molecular mechanisms related to autism

Hagerman, R., Au, J., & Hagerman, P. (2011) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-011-9084-5 · Cited by 85 · see citing works

Hippocampal granule cell pathology in epilepsy — A possible structural basis for comorbidities of epilepsy?

Hester, M. S., & Danzer, S. C. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2013.12.022 · Cited by 78 · see citing works

Theta and Alpha Oscillation Impairments in Autistic Spectrum Disorder Reflect Working Memory Deficit

Larraín-Valenzuela, J., Zamorano, F. J., Soto‐Icaza, P., Carrasco, X., Herrera, C., Daiber, F., Aboitiz, F., & Billeke, P. B. (2017) · Scientific Reports · doi:10.1038/s41598-017-14744-8 · Cited by 78 · see citing works

Modeling the functional genomics of autism using human neurons

Konopka, G., Wexler, E., Rosen, E., Mukamel, Z., Osborn, G. E., Chen, L., Lu, D., Gao, F., Gao, K., Lowe, J. K., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.60 · Cited by 76 · see citing works

Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits

Hernan, A. E., Alexander, A., Jenks, K. R., Barry, J., Lenck-Santini, P.-P., Isaeva, E., Holmes, G. L., & Scott, R. C. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.11.012 · Cited by 73 · see citing works

Identification of a distinct developmental and behavioral profile in children with Dup15q syndrome

DiStefano, C., Gulsrud, A. C., Huberty, S., Kasari, C. L., Cook, E. H., Reiter, L. T., Thibert, R. L., & Jeste, S. (2016) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-016-9152-y · Cited by 73 · see citing works

Electroencephalography in Assessment of Autism Spectrum Disorders: A Review

Milovanović, M., & Grujičić, R. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.686021 · Cited by 78 · see citing works

Mortality in Individuals With Autism, With and Without Epilepsy

Pickett, J., Xiu, E., Tuchman, R. F., Dawson, G., & Lajonchere, C. (2011) · Journal of Child Neurology · doi:10.1177/0883073811402203 · Cited by 63 · see citing works

Epilepsy and Neurodevelopmental Comorbidities in Tuberous Sclerosis Complex: A Natural History Study

Gupta, A., de Bruyn, G., Tousseyn, S., Krishnan, B., Lagae, L., Agarwal, N., Minnesota Epilepsy Group, Frost, M., Sparagana, S., LaJoie, J., et al. (2020) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2019.12.016 · Cited by 64 · see citing works

Neurobiological Basis of Autism

Silver, W. G., & Rapin, I. (2012) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2011.10.010 · Cited by 64 · see citing works

Using Wearable Sensor Technology to Measure Motion Complexity in Infants at High Familial Risk for Autism Spectrum Disorder

Wilson, R. B., Vangala, S., Elashoff, D., Safari, T., & Smith, B. A. (2021) · Sensors · doi:10.3390/s21020616 · Cited by 59 · see citing works

What is the Relationship Between Autism Spectrum Disorders and Epilepsy?

Tuchman, R. F. (2017) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2017.10.004 · Cited by 55 · see citing works

Does epilepsy in multiplex autism pedigrees define a different subgroup in terms of clinical characteristics and genetic risk?

Amiet, C., Gourfinkel‐An, I., Laurent‐Levinson, C., Bodeau, N., Génin, B., Leguern, É., Tordjman, S., & Cohen, D. (2013) · Molecular Autism · doi:10.1186/2040-2392-4-47 · Cited by 53 · see citing works

Prospective MEG biomarkers in ASD: pre-clinical evidence and clinical promise of electrophysiological signatures.

(2015) · Europe PMC (PubMed Central) · Cited by 51 · see citing works

Early-life seizures produce lasting alterations in the structure and function of the prefrontal cortex

Kleen, J. K., Sesqué, A., Wu, E. X., Miller, F. A., Hernan, A. E., Holmes, G. L., & Scott, R. C. (2011) · Epilepsy &amp; Behavior · doi:10.1016/j.yebeh.2011.07.022 · Cited by 50 · see citing works

Altered short-term plasticity in the prefrontal cortex after early life seizures

Hernan, A. E., Holmes, G. L., Isaev, D., Scott, R. C., & Isaeva, E. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.10.007 · Cited by 49 · see citing works

The Cannabidiol Use in the Treatment of Epilepsy

Matos, R. L. A., Spinola, L. A., Barboza, L. L., Garcia, D. R., França, T. C. C., & Affonso, R. S. (2017) · Revista Virtual de Química · doi:10.21577/1984-6835.20170049 · Cited by 49 · see citing works

Childhood Epilepsy and Autism Spectrum Disorders: Psychiatric Problems, Phenotypic Expression, and Anticonvulsants

Robinson, S. J. (2012) · Neuropsychology Review · doi:10.1007/s11065-012-9212-3 · Cited by 47 · see citing works

Epilepsy and seizures in young people with 22q11.2 deletion syndrome: Prevalence and links with other neurodevelopmental disorders

Eaton, C. B., Thomas, R. H., Hamandi, K., Payne, G. C., Kerr, M., Linden, D. E. J., Owen, M. J., Cunningham, A. C., Bartsch, U., Struik, S. S., et al. (2019) · Epilepsia · doi:10.1111/epi.14722 · Cited by 47 · see citing works

Animal Models of Speech and Vocal Communication Deficits Associated With Psychiatric Disorders

Konopka, G., & Roberts, T. F. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.07.001 · Cited by 47 · see citing works

Early life seizures: Evidence for chronic deficits linked to autism and intellectual disability across species and models

Bernard, P. B., & Benke, T. A. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.09.018 · Cited by 45 · see citing works

A longitudinal study of epilepsy and other central nervous system diseases in individuals with and without a history of infantile autism

Mouridsen, S. E., Rich, B., & Isager, T. (2010) · Brain and Development · doi:10.1016/j.braindev.2010.07.002 · Cited by 44 · see citing works

The role of GABAergic neural circuits in the pathogenesis of autism spectrum disorder

Di, J., Li, J., O’Hara, B. F., Alberts, I. L., Xiong, L., Li, J., & Li, X. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10005 · Cited by 42 · see citing works

Excitatory GABA induces BDNF transcription via CRTC 1 and phosphorylated CREB ‐related pathways in immature cortical cells

Fukuchi, M., Kirikoshi, Y., Mori, A., Eda, R., Ihara, D., Takasaki, I., Tabuchi, A., & Tsuda, M. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12801 · Cited by 41 · see citing works

Bioengineering tissue morphogenesis and function in human neural organoids

Fedorchak, N. J., Iyer, N. R., & Ashton, R. S. (2020) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2020.05.025 · Cited by 41 · see citing works

The role of GABAergic system in neurodevelopmental disorders: a focus on autism and epilepsy.

Sgadó, P., Dunleavy, M., Genovesi, S., Provenzano, G., & Bozzi, Y. (2011) · PubMed Central · Cited by 40 · see citing works

Interneuron Dysfunction in Syndromic Autism: Recent Advances

Takano, T. (2015) · Developmental Neuroscience · doi:10.1159/000434638 · Cited by 38 · see citing works

Autism and Epilepsy: Exploring the Relationship Using Experimental Models

Stafstrom, C. E., & Benke, T. A. (2015) · Epiliepsy currents/Epilepsy currents · doi:10.5698/1535-7511-15.4.206 · Cited by 36 · see citing works

Soy Infant Formula and Seizures in Children with Autism: A Retrospective Study

Westmark, C. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0080488 · Cited by 34 · see citing works

De novo PHACTR1 mutations in West syndrome and their pathophysiological effects

Hamada, N., Ogaya, S., Nakashima, M., Nishijo, T., Sugawara, Y., Iwamoto, I., Ito, H., Maki, Y., Shirai, K., Baba, S., et al. (2018) · Brain · doi:10.1093/brain/awy246 · Cited by 33 · see citing works

Features of autism spectrum disorder (ASD) in childhood epilepsy: a population-based study.

Reilly, C., Atkinson, P., Das, K. B., Chin, R. F. M., Aylett, S. E., Burch, V., Gillberg, C., Scott, R. C., & Neville, B. G. R. (2015) · Epilepsy &amp; Behavior · doi:10.1016/j.yebeh.2014.11.014 · Cited by 31 · see citing works

Temporal Regulation of Dendritic Spines Through NrCAM-Semaphorin3F Receptor Signaling in Developing Cortical Pyramidal Neurons

Mohan, V., Sullivan, C. S., Guo, J., Wade, S. D., Majumder, S., Agarwal, A., Anton, E. S., Temple, B., & Maness, P. F. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy004 · Cited by 31 · see citing works

Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability

Zahra, A., Wang, Y., Wang, Q., & Wu, J. (2022) · Behavioural Neurology · doi:10.1155/2022/5893519 · Cited by 30 · see citing works

Altered hippocampal-dependent memory and motor function in neuropilin 2–deficient mice

Shiflett, M. W., Gavin, M., & Tran, T. S. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.17 · Cited by 29 · see citing works

Association between GABA(A) receptor subunit polymorphisms and autism spectrum disorder (ASD)

Sesarini, C. V., Costa, L. D., Grañana, N. E., Coto, M. A. G., Pallia, R. C., & Argibay, P. F. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.07.077 · Cited by 28 · see citing works

CNTNAP4 Impacts Epilepsy Through GABAA Receptors Regulation: Evidence From Temporal Lobe Epilepsy Patients and Mouse Models

Shangguan, Y., Xu, X., Ganbat, B., Li, Y., Wang, W., Yang, Y., Lu, X., Du, C., Tian, X., & Wang, X. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx215 · Cited by 28 · see citing works

Canabinoides ajudam a desvendar aspectos etiológicos em comum e trazem esperança para o tratamento de autismo e epilepsia

Malcher‐Lopes, R. (2014) · Revista da Biologia · doi:10.7594/revbio.13.01.07 · Cited by 29 · see citing works

Neuroligin-1 Knockdown Suppresses Seizure Activity by Regulating Neuronal Hyperexcitability

Fang, M., Wei, J., Tang, B., Liu, J., Chen, L., Tang, Z., Luo, J., Chen, G., & Wang, X. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8999-8 · Cited by 27 · see citing works

Electroencephalogram (EEG) for children with autism spectrum disorder: evidential considerations for routine screening

Swatzyna, R. J., Boutros, N. N., Genovese, A., MacInerney, E. K., Roark, A. J., & Kozlowski, G. P. (2018) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-018-1225-x · Cited by 27 · see citing works

Comorbidities of early-onset temporal epilepsy: Cognitive, social, emotional, and morphologic dimensions

Mikulecká, A., Druga, R., Stuchlı́k, A., Mareš, P., & Kubová, H. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.113005 · Cited by 27 · see citing works

Neurotransmitter Systems in Autism Spectrum Disorder

Çetin, F. H., Tunca, H., Güney, E., & İşeri, E. (2015) · InTech eBooks · doi:10.5772/59122 · Cited by 24 · see citing works

Somatic Overgrowth Predisposes to Seizures in Autism Spectrum Disorders

Valvo, G., Baldini, S., Brachini, F., Apicella, F., Cosenza, A., Ferrari, A. R., Guerrini, R., Muratori, F., Romano, M. F., Santorelli, F. M., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075015 · Cited by 22 · see citing works

Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2-q13 duplications

Węgiel, J., Flory, M. J., Schanen, N. C., Cook, E. H., Nowicki, K., Kuchna, I., Imaki, H., Ma, S. Y., Wegiel, J., London, E., et al. (2015) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0241-z · Cited by 21 · see citing works

Objective measurement of movement variability using wearable sensors predicts ASD outcomes in infants at high likelihood for ASD and ADHD

Wilson, R. B., Vangala, S., Reetzke, R., Piergies, A. M. H., Ozonoff, S. J., & Miller, M. (2024) · Autism Research · doi:10.1002/aur.3150 · Cited by 21 · see citing works

N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism

Iwata, K., Matsuzaki, H., Tachibana, T., Ohno, K., Yoshimura, S., Takamura, H., Yamada, K., Matsuzaki, S., Nakamura, K., Tsuchiya, K. J., et al. (2014) · Molecular Autism · doi:10.1186/2040-2392-5-33 · Cited by 20 · see citing works

Reduced hippocampal inhibition and enhanced autism-epilepsy comorbidity in mice lacking neuropilin 2

Eisenberg, C., Subramanian, D., Afrasiabi, M., Ziobro, P., DeLucia, J., Hirschberg, P. R., Shiflett, M. W., Santhakumar, V., & Tran, T. S. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01655-6 · Cited by 20 · see citing works

Pathophysiology of Epilepsy in Autism Spectrum Disorders

Stafstrom, C. E., Hagerman, P. J., & Pessah, I. N. (2012) · Oxford University Press eBooks · doi:10.1093/med/9780199746545.003.0071 · Cited by 19 · see citing works

Interviewing individuals with an autism spectrum disorder in forensic settings

Murphy, D. (2018) · International Journal of Forensic Mental Health · doi:10.1080/14999013.2018.1518939 · Cited by 17 · see citing works

Gender and psychiatric disorders in children with epilepsy. A meta-analysis

Lax-Pericall, M. T., Bird, V. J., & Taylor, E. A. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.02.014 · Cited by 17 · see citing works

Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models

Zhang, Y., Xie, X., Hu, J., Afreen, K. S., Zhang, C., Zhuge, Q., & Yang, J. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.546484 · Cited by 16 · see citing works

Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain

Rosenberg, E. C., Bell, J. J. L., Handy, M., Soldan, S. S., Rakhade, S. N., Hilario‐Gomez, C., Folweiler, K., Jacobs, L., & Jensen, F. E. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.05.001 · Cited by 17 · see citing works

Autism with Epilepsy: A Neuropsychopharmacology Update

Canitano, R., Palumbi, R., & Scandurra, V. (2022) · Genes · doi:10.3390/genes13101821 · Cited by 16 · see citing works

Evidence for Interaction Between Markers in GABA ( A ) Receptor Subunit Genes in an A rgentinean Autism Spectrum Disorder Population

Sesarini, C. V., Costa, L. D., Naymark, M., Grañana, N. E., Cajal, A. R., Coto, M. A. G., Pallia, R. C., & Argibay, P. F. (2013) · Autism Research · doi:10.1002/aur.1353 · Cited by 16 · see citing works

Routine developmental and autism screening in an epilepsy care setting

Fisher, B., Dezort, C., Nordli, D. R., & Berg, A. T. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.06.006 · Cited by 16 · see citing works

Neuromagnetic responses to tactile stimulation of the fingers: Evidence for reduced cortical inhibition for children with Autism Spectrum Disorder and children with epilepsy

Gaetz, W. C., Jurkiewicz, M. T., Kessler, S. K., Blaskey, L. G., Schwartz, E. S., & Roberts, T. P. L. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.06.026 · Cited by 16 · see citing works

Arrested Glutamatergic Synapse Development in Human Partial Epilepsy

Anderson, M. P. (2010) · Epiliepsy currents/Epilepsy currents · doi:10.1111/j.1535-7511.2010.01386.x · Cited by 16 · see citing works

Characterization of childhood-onset complex partial seizures associated with autism spectrum disorder

Matsuo, M., Maeda, T., Ishii, K., Tajima, D., Koga, M., & Hamasaki, Y. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.01.009 · Cited by 15 · see citing works

Expression of SHANK3 in the Temporal Neocortex of Patients with Intractable Temporal Epilepsy and Epilepsy Rat Models

Zhang, Y., Gao, B., Xiong, Y., Zheng, F., Xu, X., Yang, Y., Hu, Y., & Wang, X. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0423-7 · Cited by 15 · see citing works

Audiogenic Seizures and Social Deficits: No Aggravation Found in Krushinsky–Molodkina Rats

Rebik, A., Broshevitskaya, N. D., Kuzhuget, S., Aleksandrov, P., Abbasova, K., Zaichenko, M. I., & Midzyanovskaya, I. S. (2023) · Biomedicines · doi:10.3390/biomedicines11092566 · Cited by 14 · see citing works

Frequency of risk factors and coexisting abnormalities in a population of Egyptian children with autism spectrum disorder

Meguid, N. A., Nashaat, N. H., Hashem, H. S., & Khalil, M. M. (2017) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2017.11.037 · Cited by 14 · see citing works

Fetal brain inflammation may prime hyperexcitability and behavioral dysfunction later in life

Vezzani, A. (2013) · Annals of Neurology · doi:10.1002/ana.23930 · Cited by 14 · see citing works

Dysregulation of neuropilin-2 expression in inhibitory neurons impairs hippocampal circuit development and enhances risk for autism-related behaviors and seizures

Subramanian, D., Eisenberg, C., Huang, A., Baek, J., Naveed, H., Komatireddy, S., Shiflett, M. W., Tran, T. S., & Santhakumar, V. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02839-4 · Cited by 13 · see citing works

Awareness and risk factors of autism spectrum disorder in an Egyptian population

Meguid, N. A., Nashaat, N. H., Elsaeid, A., Peana, M., Elnahry, A., & Bjørklund, G. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101781 · Cited by 13 · see citing works

The autistic brain in the context of normal neurodevelopment

Ziats, M. N., Edmonson, C. A., & Rennert, O. M. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2015.00115 · Cited by 13 · see citing works

Evaluation of Branched-Chain Amino Acids in Children with Autism Spectrum Disorder and Epilepsy

Meguid, N. A., Hashem, H. S., Ghanem, M. H., Helal, S. A., Semenova, Y. M., Hashem, S., Hashish, A. F., Chirumbolo, S., Elwan, A. M., & Bjørklund, G. (2023) · Molecular Neurobiology · doi:10.1007/s12035-022-03202-w · Cited by 12 · see citing works

De Novo Germline Mutations in SEMA5A Associated With Infantile Spasms

Wang, Q., Liu, Z., Lin, Z., Zhang, R., Lu, Y., Su, W., Li, F., Xu, X., Tu, M., Lou, Y., et al. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00605 · Cited by 12 · see citing works

Gabaergic signalling in Autism Spectrum disorders (ASD): Role of glial cells and therapeutic perspectives

Giniatullin, R. A., & Cherubini, E. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.07.003 · Cited by 11 · see citing works

The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca2+ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome

Sanderson, J. L., Freund, R. K., Castano, A. M., Benke, T. A., & Dell’Acqua, M. L. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109271 · Cited by 10 · see citing works

Evaluation of the clinical characteristics of children with autism spectrum disorder and epilepsy and the perception of their parents on quality of life

Çelik, H., Açıkel, S. B., Özdemi̇r, M., Aksoy, E., Öztoprak, Ü., Ceylan, N., & Yüksel, D. (2021) · Epilepsy Research · doi:10.1016/j.eplepsyres.2021.106599 · Cited by 11 · see citing works

Effects of immunization with heat-killed Mycobacterium vaccae on autism spectrum disorder-like behavior and epileptogenesis in a rat model of comorbid autism and epilepsy.

Smith, Z., Kubiak, R. A., Arnold, M. R., Loupy, K., Taylor, J. A., Crist, T., Bernier, A. E., D'Angelo, H., Heinze, J. D., Lowry, C., et al. (2020) · Brain, behavior, and immunity · doi:10.1016/j.bbi.2020.05.034 · Cited by 9 · see citing works

Gamma oscillatory activity in vitro: a model system to assess pathophysiological mechanisms of comorbidity between autism and epilepsy

Subramanian, D., Pralong, É., Daniel, R. T., Chacko, A. G., Stoop, R., & Babu, K. S. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0065-7 · Cited by 9 · see citing works

SUMMARY

Brooks‐Kayal, A. R. (2014)

Molecular mechanisms of cognitive and behavioral comorbidities of epilepsy in children

Brooks‐Kayal, A. R. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2010.02906.x · Cited by 79 · see citing works

Genetic research progress of syndromes with the comorbidity of epilepsy and autism

Zheng, J. (2015) · International journal of pediatrics · doi:10.3760/cma.j.issn.1673-4408.2015.01.029

Autism with epilepsy: A neurodevelopmental association

Canitano, R. (2014) · Archivio Istituzionale della Ricerca - Università degli Studi dell Aquila · Cited by 1 · see citing works

Epilepsy and Autism: Neurodevelopmental Perspective

Tuchman, R. F., & Cuccaro, M. L. (2011) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-011-0195-x · Cited by 131 · see citing works