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Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome
Abstract
We conducted a follow-up of a previously reported study of internet-delivered cognitive behavior therapy (CBT) for IBS, based on exposure and mindfulness exercises (Ljótsson et al. (2010). Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome - a randomized controlled trial. Behaviour Research and Therapy, 48, 531-539). Seventy-five participants from the original sample of 85 (88%) reported follow-up data at 15-18 months (mean 16.4 months) after completing treatment. The follow-up sample included participants from both the original study's treatment group and waiting list after it had been crossed over to treatment. Intention-to-treat analysis showed that treatment gains were maintained on all outcome measures, including IBS symptoms, quality of life, and anxiety related to gastrointestinal symptoms, with mainly large effect sizes (within-group Cohen's d=0.78-1.11). A total of fifty participants (59% of the total original sample; 52% of the original treatment group participants and 65% of the original waiting list participants) reported adequate relief of symptoms. Improvements at follow-up were more pronounced for the participants that had completed the full treatment and maintenance of improvement did not seem to be dependent on further treatment seeking. This study suggests that internet-delivered CBT based on exposure and mindfulness has long-term beneficial effects for IBS-patients.
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“there is growing evidence for the effectiveness of mindfulness courses for people with long-term medical conditions.”
From Distant delivery of a mindfulness-based intervention for people with Parkinson's disease: The study protocol of a randomised pilot trial (2017) · cites this paper as [20]
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“Further, there is evidence that distance-delivered mindfulness interventions can also be effective in people with chronic medical conditions [20–23].”
From Distant delivery of a mindfulness-based intervention for people with Parkinson's disease: The study protocol of a randomised pilot trial (2017) · cites this paper as [20]
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“A follow-up study also showed maintenance of improvements over a 15-18 months period [16]”
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Ryan, A., Ferreira, N. B., Moffat, H., Eugenicos, M. P., Howson, W., Casburn-Jones, A., Moroni, F., Stevens, P., Wolters, M. K., & Gillanders, D. T. (2025) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2025.100887 · Cited by 1
Erfan, A., Noorbala, A., Mohammadi, A., & Adibi, P. (2018) · International Journal of Educational and Psychological Researches · doi:10.4103/jepr.jepr_46_16 · Cited by 1
Efficacy of Mindfulness Based on Stress Reduction on Rat Disorders in Patients with Irritable Bowel
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Metadata
- Authors
- Ljótsson, B., Hedman, E., Lindfors, P., Hursti, T., Lindefors, N., Andersson, G., & Rück, C.
- Affiliations
- Karolinska Institutet (SE)
- Sabbatsberg Hospital (SE)
- Uppsala University (SE)
- Linköping University (SE)
- Corresponding author
- Ljótsson, Brjánn
- Venue
- Behaviour Research and Therapy
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 49
- Issue
- 1
- Pages
- 58-61
- ISSN
- 0005-7967 (ISSN-L)
- OpenAlex
- W1982189650
- Cited by
- 113
- References
- 30
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 9 · 2023: 7 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 5 · 2018: 9 · 2017: 8 · 2016: 5 · 2015: 6 · 2014: 13 · 2013: 15 · 2012: 7
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behaviour Research and Therapy (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Stockholms Läns Landsting
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- irritable bowel syndrome, internet-based cognitive behavioral therapy, exposure therapy, mindfulness-based interventions, quality of life, symptom relief
- MeSH terms
- Adult, Anxiety, Female, Follow-Up Studies, Humans, Implosive Therapy, Male, Quality of Life, Therapy, Computer-Assisted, Cognitive Behavioral Therapy, Meditation, Irritable Bowel Syndrome
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