Computerised cognitive behavioural therapy for psychological distress in patients with physical illnesses: a systematic review
Abstract
Whilst cognitive behaviour therapy (CBT) has been shown to improve outcomes in patients with chronic physical illnesses, there are barriers to its implementation which computerised CBT (CCBT) may overcome. We reviewed all studies of CCBT for treating psychological distress (PD) in chronic physical illness populations. Systematic searches were undertaken in July, 2013. All articles about CCBT for PD secondary to physical illness were included. Twenty-nine studies (thirty papers) were included. Overall, the quality of evidence was poor. Studies about irritable bowel syndrome demonstrated the best evidence. The evidence for CCBT in the treatment of PD in physical illness patients is modest, perhaps due to the seldom use of PD screening. More robust research designs including longer follow up periods are required. Nevertheless, no studies reported a negative effect of CCBT on any outcome measures.
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It has been recommended that iCBT studies use attention control groups as comparators.
“However, it has been recommended that iCBT studies should use attention control groups as comparators. 43,44”
Digital health interventions can provide remote access to effective treatments, such as computerised cognitive behavioural therapy for mental health and somatic problems.
“provide remote access to effective treatments, for example computerised cognitive behavioural therapy for mental health and somatic problems. 10–14”
From Evaluating Digital Health Interventions (2016) · cites this paper as [12]
Computerized CBT could improve symptoms of anxiety and depression in patients with somatic conditions.
“a systematic review reported that computerized CBT could also improve symptoms of anxiety and depression [35].”
From Effectiveness and cost-effectiveness of guided Internet- and mobile-based CBT for adolescents and young adults with chronic somatic conditions and comorbid depression and anxiety symptoms (youthCOACHCD): study protocol for a multicentre randomized controlled trial (2020) · cites this paper as [35]
An active control group is recommended in a systematic review.
“As recommended in a systematic review [13], we used an active control group”
From An Internet-Based Cognitive Behavioral Therapy Program Adapted to Patients With Cardiovascular Disease and Depression: Randomized Controlled Trial (2019) · cites this paper as [13]
Generic iCBT programs may not be optimal for targeting depression in patients with chronic diseases because they are not tailored to the disease context.
“However, generic iCBT programs may not be optimal for targeting depression in patients with chronic diseases, as these programs are not tailored to the context of the disease [12,13].”
From An Internet-Based Cognitive Behavioral Therapy Program Adapted to Patients With Cardiovascular Disease and Depression: Randomized Controlled Trial (2019) · cites this paper as [13]
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“…(Abbott et al., 2009, see row 22 of Table 2; Haemmerli et al., 2010, see row 8; Hunt et al., 2009, see row 26; Jones & McCabe, 2011, see row 12; Kuhl et al., 2009, see row 2; Owen et al., 2005, See Row 5; Ruehlman et al., 2012, see row 29; Sexton et al., 2010, see row 9; van Bastelaar et al.,…”
BackgroundMcCombie, A., Gearry, R. B., & Mulder, R. (2013) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.11.011 · Cited by 15 · see citing works
Self-citationTreatment of Comorbid Depression in Medical Illness
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Flagged first, then by citations
1 of the 100 references couldn’t be matched to a known paper.
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Evaluating Digital Health Interventions
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Internet-Based Interventions in Chronic Somatic Disease
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Implementation of an eHealth self-management care path for chronic somatic conditions
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“43,44 The comparator in the Schneider et al.’s 20 study was a waitlist, and the comparator in the pre-sent study was an ODF.”
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The Internet and CBT: A New Clinical Application of an Effective Therapy
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Prognosis of stress-associated gastroenterologic diseases: a retrospective study
Dorofeev, I. I., Владимирович, К. А., Порожников, П. А., Викторович, Д. К., Мотасов, Г. П., Tyagnerev, A. T., Михайлович, Ч. И., & Yatmanov, A. N. (2025) · Marine Medicine · doi:10.22328/2413-5747-2025-11-2-111-119
Prognosis of stress-associated diseases in military personnel: retrospective study
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- Authors
- McCombie, A., Gearry, R., Andrews, J., Mikocka-Walus, A., & Mulder, R.
- Affiliations
- University of Otago (NZ)
- Royal Adelaide Hospital (AU)
- Venue
- Journal of Clinical Psychology in Medical Settings
- Published
- 2015-02-11
- Volume
- 22
- Issue
- 1
- Pages
- 20-44
- ISSN
- 1068-9583 (ISSN-L)
- 1573-3572
- OpenAlex
- W2165931088
- Cited by
- 42
- References
- 100
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 6 · 2020: 2 · 2019: 7 · 2018: 5 · 2017: 3 · 2016: 3 · 2015: 2
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Clinical Psychology in Medical Settings (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- University of Otago
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- psychological distress, chronic physical illness, irritable bowel syndrome, psychological screening, implementation barriers
- MeSH terms
- Mental Disorders, Chronic Disease, Humans, Stress, Psychological, Therapy, Computer-Assisted, Cognitive Behavioral Therapy, Internet
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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