Neurochemical Modulation in Posteromedial Default-mode Network Cortex Induced by Transcranial Magnetic Stimulation
Open accessAbstract
Background The Default Mode Network (DMN) is severely compromised in several psychiatric and neurodegenerative disorders where plasticity alterations are observed. Glutamate and GABA are the major excitatory and inhibitory brain neurotransmitters respectively and are strongly related to plasticity responses and large-scale network expression.Objective To investigate whether regional Glx (Glutamate + Glutamine) and GABA could be modulated within the DMN after experimentally-controlled induction of plasticity and to study the effect of intrinsic connectivity over brain responses to stimulation.Methods We applied individually-guided neuronavigated Theta Burst Stimulation (TBS) to the left inferior parietal lobe (IPL) in-between two magnetic resonance spectroscopy (MRS) acquisitions to 36 young subjects. A resting-state fMRI sequence was also acquired before stimulation.Results After intermittent TBS, distal GABA increases in posteromedial DMN areas were observed. Instead, no significant changes were detected locally, in left IPL areas. Neurotransmitter modulation in posteromedial areas was related to baseline fMRI connectivity between this region and the TBS-targeted area.Conclusions The prediction of neurotransmitter modulation by connectivity highlights the relevance of connectivity patterns to understand brain responses to plasticity-inducing protocols. The ability to modulate GABA in a key core of the DMN by means of TBS may open new avenues to evaluate plasticity mechanisms in a key area for major neurodegenerative and psychiatric conditions.
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Theta burst stimulation via transcranial magnetic stimulation has been used successfully to increase GABA within the DMN.
“theta burst stimulation via transcranial magnetic stimulation has been used successfully to increase GABA within the DMN [200].”
From Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease (2019) · cites this paper as [200]
Cites
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190 · see citing works
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812 · see citing works
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553 · see citing works
Rossi, S., Hallett, M., Rossini, P. M., & Pascual-Leone, A. (2009) · Clinical Neurophysiology · doi:10.1016/j.clinph.2009.08.016 · Cited by 5,367 · see citing works
Correspondence of the brain's functional architecture during activation and rest
Smith, S. M., Fox, P. T., Miller, K. L., Glahn, D. C., Fox, P. M., Mackay, C. E., Filippini, N., Watkins, K. E., Toro, R., Laird, A. R., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905267106 · Cited by 5,150 · see citing works
Mapping the structural core of human cerebral cortex
Hagmann, P., Cammoun, L., Gigandet, X., Meuli, R., Honey, C. J., Wedeen, V. J., & Sporns, O. (2008) · PLoS Biology · doi:10.1371/journal.pbio.0060159 · Cited by 4,173 · see citing works
Theta Burst Stimulation of the Human Motor Cortex
Huang, Y.-Z., Edwards, M. J., Rounis, E., Bhatia, K. P., & Rothwell, J. C. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.033 · Cited by 4,158 · see citing works
Greicius, M. D., Srivastava, G., Reiss, A. L., & Menon, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308627101 · Cited by 3,684 · see citing works
Estimation of metabolite concentrations from localized in vivo proton NMR spectra
Provencher, S. W. (1993) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910300604 · Cited by 3,659 · see citing works
What we can do and what we cannot do with fMRI
Logothetis, N. K. (2008) · Nature · doi:10.1038/nature06976 · Cited by 3,612 · see citing works
Searching for a baseline: Functional imaging and the resting human brain
Gusnard, D. A., & Raichle, M. E. (2001) · Nature Reviews Neuroscience · doi:10.1038/35094500 · Cited by 3,371 · see citing works
Neocortical excitation/inhibition balance in information processing and social dysfunction
Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature · doi:10.1038/nature10360 · Cited by 2,454 · see citing works
Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network
Greicius, M. D., Supekar, K., Menon, V., & Dougherty, R. F. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn059 · Cited by 2,175 · see citing works
Buckner, R. L., Snyder, A. Z., Shannon, B. J., LaRossa, G., Sachs, R., Fotenos, A. F., Sheline, Y. I., Klunk, W. E., Mathis, C. A., Morris, J. C., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2177-05.2005 · Cited by 2,140 · see citing works
Evidence for a Frontoparietal Control System Revealed by Intrinsic Functional Connectivity
Vincent, J. L., Kahn, I., Snyder, A. Z., Raichle, M. E., & Buckner, R. L. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90355.2008 · Cited by 1,869 · see citing works
Proton NMR chemical shifts and coupling constants for brain metabolites
Govindaraju, V., Young, K., & Maudsley, A. A. (2000) · NMR in Biomedicine · doi:10.1002/1099-1492(200005)13:3 · Cited by 1,695 · see citing works
Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Palop, J. J., & Mucke, L. (2010) · Nature Neuroscience · doi:10.1038/nn.2583 · Cited by 1,651 · see citing works
Neural plasticity in the ageing brain
Burke, S. N., & Barnes, C. A. (2005) · Nature reviews. Neuroscience · doi:10.1038/nrn1809 · Cited by 1,600 · see citing works
Disruption of Large-Scale Brain Systems in Advanced Aging
Andrews-Hanna, J. R., Snyder, A. Z., Vincent, J. L., Lustig, C., Head, D., Raichle, M. E., & Buckner, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.038 · Cited by 1,592 · see citing works
Fox, M. D., Buckner, R. L., White, M. P., Greicius, M. D., & Pascual-Leone, A. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.04.028 · Cited by 1,270 · see citing works
Aberrant “Default Mode” Functional Connectivity in Schizophrenia
Garrity, A. G., Pearlson, G. D., McKiernan, K., Lloyd, D., Kiehl, K. A., & Calhoun, V. D. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.450 · Cited by 1,114 · see citing works
Deng, Z., Lisanby, S. H., & Peterchev, A. V. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.02.005 · Cited by 1,079 · see citing works
Strafella, A. P., Paus, T., Barrett, J., & Dagher, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-15-j0003.2001 · Cited by 1,058 · see citing works
The role of default network deactivation in cognition and disease
Anticevic, A., Cole, M. W., Murray, J. D., Corlett, P. R., Wang, X.-J., & Krystal, J. H. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2012.10.008 · Cited by 978 · see citing works
Polarity-Sensitive Modulation of Cortical Neurotransmitters by Transcranial Stimulation
Stagg, C. J., Best, J. G., Stephenson, M. C., O’Shea, J., Wylezinska, M., Kincses, Z. T., Morris, P. G., Matthews, P. M., & Johansen‐Berg, H. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4432-08.2009 · Cited by 942 · see citing works
Ridding, M. C., & Ziemann, U. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.190314 · Cited by 787 · see citing works
Key role of coupling, delay, and noise in resting brain fluctuations
Deco, G., Jirsa, V., McIntosh, A. R., Sporns, O., & Kötter, R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901831106 · Cited by 756 · see citing works
Rombouts, S. A. R. B., Barkhof, F., Goekoop, R., Stam, C. J., & Scheltens, P. (2005) · Human Brain Mapping · doi:10.1002/hbm.20160 · Cited by 734 · see citing works
Intrinsic connections and architectonics of posterior parietal cortex in the rhesus monkey
Pandya, D., & Seltzer, B. (1982) · The Journal of comparative neurology · doi:10.1002/cne.902040208 · Cited by 730 · see citing works
Consensus: Motor cortex plasticity protocols
Ziemann, U., Paulus, W., Nitsche, M. A., Pascual-Leone, A., Byblow, W. D., Berardelli, A., Siebner, H. R., Classen, J., Cohen, L. G., & Rothwell, J. C. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.006 · Cited by 639 · see citing works
Strafella, A., Paus, T., Fraraccio, M., & Dagher, A. (2003) · Brain : a journal of neurology · doi:10.1093/brain/awg268 · Cited by 629 · see citing works
The after-effect of human theta burst stimulation is NMDA receptor dependent
Huang, Y.-Z., Chen, R.-S., Rothwell, J. C., & Wen, H.-Y. (2007) · Clinical Neurophysiology · doi:10.1016/j.clinph.2007.01.021 · Cited by 618 · see citing works
Targeted enhancement of cortical-hippocampal brain networks and associative memory
Wang, J. X., Rogers, L. M., Gross, E. Z., Ryals, A. J., Dokucu, M. E., Brandstatt, K. L., Hermiller, M. S., & Voss, J. L. (2014) · Science · doi:10.1126/science.1252900 · Cited by 615 · see citing works
The Role of GABA in Human Motor Learning
Stagg, C. J., Bachtiar, V., & Johansen‐Berg, H. (2011) · Current Biology · doi:10.1016/j.cub.2011.01.069 · Cited by 600 · see citing works
Noninvasive brain stimulation: from physiology to network dynamics and back
Dayan, E., Censor, N., Buch, E. R., Sandrini, M., & Cohen, L. G. (2013) · Nature Neuroscience · doi:10.1038/nn.3422 · Cited by 588 · see citing works
Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
Mullins, P. G., McGonigle, D. J., Tuura, R., Puts, N. A. J., Vidyasagar, R., Evans, J., & Edden, R. A. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.12.004 · Cited by 555 · see citing works
Rae, C. D. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1199-5 · Cited by 491 · see citing works
Mars, R. B., Jbabdi, S., Sallet, J., O’Reilly, J. X., Croxson, P. L., Olivier, E., Noonan, M. P., Bergmann, C., Mitchell, A. S., Baxter, M. G., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5102-10.2011 · Cited by 472 · see citing works
Uddin, L. Q., Supekar, K., Amin, H., Rykhlevskaia, E. I., Nguyen, D. A., Greicius, M. D., & Menon, V. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq011 · Cited by 449 · see citing works
Cho, S. S., & Strafella, A. P. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006725 · Cited by 416 · see citing works
Stagg, C. J., Bestmann, S., Constantinescu, A. O., Moreno, L. M., Allman, C., Ralf Mekle, A., Woolrich, M. W., Near, J., Johansen‐Berg, H., & Rothwell, J. C. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.216978 · Cited by 401 · see citing works
Cortical Connections of the Inferior Parietal Cortical Convexity of the Macaque Monkey
Rozzi, S., Calzavara, R., Belmalih, A., Borra, E., Gregoriou, G. G., Matelli, M., & Luppino, G. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj076 · Cited by 399 · see citing works
Human Cerebral Cortex: Localization, Parcellation, and Morphometry with Magnetic Resonance Imaging
Rademacher, J., Galaburda, A. M., Kennedy, D. N., Filipek, P. A., & Caviness, V. S. (1992) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1992.4.4.352 · Cited by 376 · see citing works
GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI
Northoff, G., Walter, M., Schulte, R. F., Beck, J., Dydak, U., Henning, A., Boeker, H., Grimm, S., & Boesiger, P. (2007) · Nature Neuroscience · doi:10.1038/nn2001 · Cited by 359 · see citing works
Lynch, C. J., Uddin, L. Q., Supekar, K., Khouzam, A., Phillips, J. M., & Menon, V. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.013 · Cited by 357 · see citing works
The structural–functional connectome and the default mode network of the human brain
Horn, A., Ostwald, D., Reisert, M., & Blankenburg, F. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.09.069 · Cited by 355 · see citing works
Rapid Modulation of GABA Concentration in Human Sensorimotor Cortex During Motor Learning
Floyer-Lea, A., Wylezinska, M., Kincses, Z. T., & Matthews, P. M. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00346.2005 · Cited by 350 · see citing works
Receptor architecture of human cingulate cortex: Evaluation of the four‐region neurobiological model
Palomero‐Gallagher, N., Vogt, B. A., Schleicher, A., Mayberg, H. S., & Zilles, K. (2008) · Human Brain Mapping · doi:10.1002/hbm.20667 · Cited by 346 · see citing works
Neurochemical Effects of Theta Burst Stimulation as Assessed by Magnetic Resonance Spectroscopy
Stagg, C. J., Wylezinska, M., Matthews, P. M., Johansen‐Berg, H., Jezzard, P., Rothwell, J. C., & Bestmann, S. (2009) · Journal of Neurophysiology · doi:10.1152/jn.91060.2008 · Cited by 292 · see citing works
Eldaief, M. C., Halko, M. A., Buckner, R. L., & Pascual‐Leone, Á. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113103109 · Cited by 288 · see citing works
Clark, V. P., Coffman, B. A., Trumbo, M., & Gasparovic, C. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.05.244 · Cited by 284 · see citing works
Caspers, S., Eickhoff, S. B., Tobias Rick, A., Anette Von Kapri, A., Kuhlen, T., Huang, R., Shah, N. J., & Zilles, K. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.027 · Cited by 246 · see citing works
Morecraft, R. J., Cipolloni, P. B., Stilwell‐Morecraft, K. S., Gedney, M., & Pandya, D. Ν. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10980 · Cited by 238 · see citing works
Duncan, N. W., Wiebking, C., & Northoff, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.07.016 · Cited by 220 · see citing works
Kapogiannis, D., Reiter, D. A., Willette, A. A., & Mattson, M. P. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2012.09.029 · Cited by 211 · see citing works
Bestmann, S., Swayne, O. B. C., Blankenburg, F., Ruff, C. C., Haggard, P., Weiskopf, N., Josephs, O., Driver, J., Rothwell, J. C., & Ward, N. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm159 · Cited by 208 · see citing works
Nitsche, M. A., Müller‐Dahlhaus, F., Paulus, W., & Ziemann, U. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.232975 · Cited by 199 · see citing works
FUNCTIONAL CONNECTIVITY IN SCHIZOPHRENIA
van den Heuvel, M. P., Mandl, R. C. W., Scheeuwe, T., Kahn, W., Kahn, R. S., & Pol, H. E. H. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.02.894 · Cited by 190 · see citing works
Khalsa, S., Mayhew, S. D., Chechlacz, M., Bagary, M. S., & Bagshaw, A. P. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.12.022 · Cited by 180 · see citing works
Cortical Plasticity in Alzheimer’s Disease in Humans and Rodents
Battaglia, F., Wang, H.-Y., Ghilardi, M. F., Gashi, E., Quartarone, A., Friedman, E., & Nixon, R. A. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.02.027 · Cited by 175 · see citing works
Electrophysiological correlates of default-mode processing in macaque posterior cingulate cortex
Hayden, B. Y., Smith, D. V., & Platt, M. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812035106 · Cited by 169 · see citing works
Hu, Y., Chen, X., Gu, H., & Yang, Y. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1973-13.2013 · Cited by 167 · see citing works
The Dynamic Nature of Top-Down Signals Originating from Prefrontal Cortex: A Combined fMRI–TMS Study
Lee, T. G., & D’Esposito, M. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0627-12.2012 · Cited by 161 · see citing works
Heise, K.-F., Zimerman, M., Hoppe, J., Gerloff, C. P., Wegscheider, K., & Hummel, F. C. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4094-12.2013 · Cited by 149 · see citing works
Magnetic Resonance Spectroscopy as a tool to study the role of GABA in motor-cortical plasticity
Stagg, C. J. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.01.009 · Cited by 143 · see citing works
Dastjerdi, M., Foster, B. L., Nasrullah, S., Rauschecker, A. M., Dougherty, R. F., Townsend, J. D., Chang, C., Greicius, M. D., Menon, V., Kennedy, D. P., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1017098108 · Cited by 137 · see citing works
Hunter, M. A., Coffman, B. A., Gasparovic, C., Calhoun, V. D., Trumbo, M., & Clark, V. P. (2014) · Brain Research · doi:10.1016/j.brainres.2014.09.066 · Cited by 132 · see citing works
Dídac Vidal-piñeiro, A., eValls-Pedret, C., Fernández‐Cabello, S., Arenaza‐Urquijo, E. M., Sala-Llonch, R., Solana, E., Bargalló, N., Junqué, C., Ros, E., & David Bartrés-faz, A. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00256 · Cited by 126 · see citing works
Self-citationAtlas of Cytoarchitectonics of the Adult Human Cerebral Cortex
von Economo, C., Koskinas, G. N., & Triarhou, L. C. (2007) · KARGER eBooks · doi:10.1159/isbn.978-3-8055-8289-6 · Cited by 125 · see citing works
Frontal GABA Levels Change during Working Memory
Michels, L., Martin, E., Klaver, P., Edden, R. A. E., Zelaya, F. O., Lythgoe, D. J., Lüchinger, R., Brandeis, D., & Tuura, R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031933 · Cited by 125 · see citing works
Tremblay, S., Beaulé, V., Proulx, S., Beaumont, L. D., Marjańska, M., Doyon, J., Pascual‐Leone, Á., Lassonde, M. C., & Théoret, H. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00704.2012 · Cited by 120 · see citing works
Palop, J. J., Mucke, L., & Roberson, E. D. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-744-0_17 · Cited by 104 · see citing works
Falkenberg, L. E., Westerhausen, R., Specht, K., & Hugdahl, K. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115628109 · Cited by 81 · see citing works
Riese, F., Gietl, A. F., Zoelch, N., Henning, A., Tuura, R., Kälin, A. M., Leh, S. E., Buck, A., Warnock, G., Edden, R. A. E., et al. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.07.030 · Cited by 81 · see citing works
Brain dynamic neurochemical changes in dystonic patients: A magnetic resonance spectroscopy study
Marjańska, M., Lehéricy, S., Valabrègue, R., Popa, T., Worbe, Y., Russo, M., Auerbach, E. J., Grabli, D., Bonnet, C., Galléa, C., et al. (2012) · Movement Disorders · doi:10.1002/mds.25279 · Cited by 73 · see citing works
Abnormal modulation of corticospinal excitability in adults with Asperger’s syndrome
Oberman, L. M., Eldaief, M. C., Fecteau, S., Ifert‐Miller, F., Tormos, J. M., & Pascual‐Leone, Á. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08172.x · Cited by 72 · see citing works
Dídac Vidal-piñeiro, A., Martín-Trias, P., Arenaza‐Urquijo, E. M., Sala‐Llonch, R., Clemente, I. C., Mena-Sánchez, I., Bargalló, N., Falcón, C., Pascual‐Leone, Á., & David Bartrés-faz, A. (2014) · Brain stimulation · doi:10.1016/j.brs.2013.12.016 · Cited by 68 · see citing works
Self-citationGuggisberg, A. G., Dubach, P., Hess, C. W., Wüthrich, C., & Mathis, J. (2001) · Clinical Neurophysiology · doi:10.1016/s1388-2457(01)00677-0 · Cited by 65 · see citing works
Friedman, S. D., Baker, L. D., Soo Borson, B., Jensen, J. E., Barsness, S. M., Craft, S., Merriam, G. R., Otto, R. K., Novotny, E. J., & Vitiello, M. V. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.1425 · Cited by 57 · see citing works
Resting-state Modulation of Alpha Rhythms by Interference with Angular Gyrus Activity
Capotosto, P., Babiloni, C., Romani, G. L., & Corbetta, M. (2013) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00460 · Cited by 53 · see citing works
Pujol, N., Penadés, R., Rametti, G., Catalán, R., Vidal-Piñeiro, D., Palacios, E., Bargallo, N., Bernardo, M., & Junqué, C. (2013) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2013.06.008 · Cited by 21 · see citing works
Self-citationCombining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network
Halko, M. A., Eldaief, M. C., Horvath, J. C., & Pascual‐Leone, Á. (2010) · Journal of Visualized Experiments · doi:10.3791/2271 · Cited by 18 · see citing works
Gao, J., Cheung, R. T. F., Chan, Y., Chu, L., & Lee, T. M. C. (2012) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2012.672948 · Cited by 16 · see citing works
Todd, G., & Ridding, M. C. (2010) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2010-0565 · Cited by 12 · see citing works
Cho, S., & Strafella, A. (2009) · NeuroImage · doi:10.1016/s1053-8119(09)71915-9 · Cited by 4 · see citing works
Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network
Halko, M. A., Eldaief, M. C., Horvath, J. C., & Pascual‐Leone, Á. (2010) · Journal of Visualized Experiments · doi:10.3791/2271-v · Cited by 2 · see citing works
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1 of the 87 references couldn’t be matched to a known paper.
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Accelerated TMS for Depression: A systematic review and meta-analysis
Sonmez, A. I., Camsari, D. D., Nandakumar, A. L., Voort, J. L. V., Kung, S., Lewis, C. P., & Croarkin, P. E. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.12.041 · Cited by 257 · see citing works
Yaakub, S. N., White, T. A., Roberts, J., Martin, E. M., Verhagen, L., Stagg, C. J., Hall, S., & Fouragnan, E. F. (2023) · Nature Communications · doi:10.1038/s41467-023-40998-0 · Cited by 201 · see citing works
Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
Najm, R., Jones, E. A., & Huang, Y. (2019) · Molecular Neurodegeneration · doi:10.1186/s13024-019-0324-6 · Cited by 183 · see citing works
Targeted transcranial theta-burst stimulation alters fronto-insular network and prefrontal GABA
Iwabuchi, S. J., Raschke, F., Auer, D. P., Liddle, P. F., Lankappa, S. T., & Palaniyappan, L. K. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.09.043 · Cited by 102 · see citing works
Hanlon, C. A., Dowdle, L. T., & Henderson, J. (2018) · Pharmacological Reviews · doi:10.1124/pr.116.013649 · Cited by 94 · see citing works
Li, C., Huang, Y., Bai, Y., Tsai, S., Su, T., & Cheng, C. (2019) · Human Brain Mapping · doi:10.1002/hbm.24485 · Cited by 93 · see citing works
Hartwigsen, G., & Volz, L. J. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117449 · Cited by 79 · see citing works
Puri, R., Hinder, M. R., Fujiyama, H., Gomez, R., Carson, R. G., & Summers, J. J. (2015) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2015.00107 · Cited by 72 · see citing works
Regional balance between glutamate+glutamine and GABA+ in the resting human brain
Steel, A., Mikkelsen, M. E., Edden, R. A. E., & Robertson, C. E. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117112 · Cited by 70 · see citing works
Ji, G., Yu, F., Liao, W., & Wang, K. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.01.035 · Cited by 64 · see citing works
Baeken, C., Lefaucheur, J., & Schuerbeek, P. V. (2017) · Clinical Neurophysiology · doi:10.1016/j.clinph.2017.06.243 · Cited by 66 · see citing works
Abellaneda‐Pérez, K., Vaqué‐Alcázar, L., Dídac Vidal-piñeiro, A., Jannati, A., Solana, E., Bargalló, N., Santarnecchi, E., Pascual‐Leone, Á., & David Bartrés-faz, A. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.11.036 · Cited by 55 · see citing works
Self-citationCuypers, K., & Marsman, A. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117394 · Cited by 57 · see citing works
Precise Modulation Strategies for Transcranial Magnetic Stimulation: Advances and Future Directions
Zhong, G., Yang, Z., & Jiang, T. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00781-x · Cited by 48 · see citing works
Non-Invasive Brain Stimulation in Dementia: A Complex Network Story
Pini, L., Manenti, R., Cotelli, M., Pizzini, F. B., Frisoni, G. B., & Pievani, M. (2018) · Neurodegenerative Diseases · doi:10.1159/000495945 · Cited by 41 · see citing works
Abellaneda‐Pérez, K., Potash, R. M., Pascual‐Leone, Á., & Sacchet, M. D. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105862 · Cited by 40 · see citing works
Aceves-Serrano, L., Neva, J. L., & Doudet, D. J. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.787403 · Cited by 33 · see citing works
Antonioni, A., Martorana, A., Santarnecchi, E., Hampel, H. J., & Koch, G. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70337 · Cited by 31 · see citing works
Transcranial Electric Stimulation for Precision Medicine: A Spatiomechanistic Framework
Yavari, F., Nitsche, M. A., & Ekhtiari, H. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00159 · Cited by 30 · see citing works
Oberman, L. M., Hynd, M., Nielson, D. M., Towbin, K. E., Lisanby, S. H., & Stringaris, A. K. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.642847 · Cited by 30 · see citing works
Neurophysiological markers of response to theta burst stimulation in youth depression
Dhami, P., Atluri, S., Lee, J. C., Knyahnytska, Y., Croarkin, P. E., Blumberger, D. M., Daskalakis, Z. J., & Farzan, F. (2020) · Depression and Anxiety · doi:10.1002/da.23100 · Cited by 29 · see citing works
Ghin, F., Beste, C., & Stock, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.12.031 · Cited by 29 · see citing works
Han, X., Zhu, Z., Luan, J., Lv, P., Xin, X., Zhang, X., Shmuel, A., Yao, Z., Ma, G., & Zhang, B. (2023) · European Journal of Radiology Open · doi:10.1016/j.ejro.2023.100495 · Cited by 28 · see citing works
Su, H., Chen, T., Zhong, N., Jiang, H., Du, J., Ke, X., Xu, D., Wang, Z., & Zhao, M. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.02.95 · Cited by 25 · see citing works
Brandt, S. J., Oral, H. Y., Arellano-Bravo, C., Plawecki, M. H., Hummer, T. A., & Francis, M. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01046-1 · Cited by 23 · see citing works
Abellaneda‐Pérez, K., Vaqué‐Alcázar, L., Solé‐Padullés, C., & David Bartrés-faz, A. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24514 · Cited by 21 · see citing works
The use of theta burst stimulation in patients with schizophrenia – A systematic review
Poorganji, M., Göke, K., Zomorrodi, R., Voineskos, D., Rajji, T. K., Daskalakis, Z. J., & Blumberger, D. M. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.10.005 · Cited by 22 · see citing works
Stoby, K. S., Rafique, S. A., Oeltzschner, G., & Steeves, J. K. E. (2022) · Brain and Behavior · doi:10.1002/brb3.2478 · Cited by 21 · see citing works
Vaqué‐Alcázar, L., Mulet‐Pons, L., Abellaneda‐Pérez, K., Solé‐Padullés, C., Cabello‐Toscano, M. R., Macià, D., Sala‐Llonch, R., Bargalló, N., Sánchez, J. S., Cattaneo, G., et al. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.695232 · Cited by 19 · see citing works
Self-citationCember, A., Deck, B. L., Kelkar, A. S., Faseyitan, O. K., Zimmerman, J. P., Erickson, B. A., Elliott, M. A., Coslett, H. B., Hamilton, R. H., Reddy, R. D., et al. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119191 · Cited by 17 · see citing works
Madore, M. R., Poh, E. Z., Bollard, S. J., Rivera, J., Taylor, J. L., Cheng, J. J., Booth, E., Nable, M., Heath, A. M., Yesavage, J. A., et al. (2021) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2021.109261 · Cited by 16 · see citing works
Spagnolo, P. A., Pérez, L. J. G., Terraneo, A., Gallimberti, L., & Bonci, A. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14313 · Cited by 16 · see citing works
Spurny‐Dworak, B., Godbersen, G. M., Reed, M. B., Unterholzner, J., Vanicek, T., Baldinger, P., Hahn, A., Kranz, G. S., Bogner, W., Lanzenberger, R. R., et al. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.913274 · Cited by 15 · see citing works
Wang, J., Deng, X., Hu, Y., Yue, J., Ge, Q., Li, X., & Feng, Z. (2022) · Human Brain Mapping · doi:10.1002/hbm.26045 · Cited by 9 · see citing works
Network-targeted transcranial magnetic stimulation (TMS) for mild cognitive impairment (MCI)
Taylor, J. L., Bhatt, P., Hernandez, B., Iv, M., Adamson, M. M., Heath, A. M., Yesavage, J. A., & McNerney, M. W. (2025) · NeuroImage Clinical · doi:10.1016/j.nicl.2025.103819 · Cited by 6 · see citing works
Dhami, P., Lee, J. C., Schwartzmann, B., Knyahnytska, Y., Atluri, S., Christie, G. J., Croarkin, P. E., Blumberger, D. M., Daskalakis, Z. J., Moreno, S., et al. (2022) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2022.100439 · Cited by 6 · see citing works
Hendrikse, J. J., Thompson, S. C. H., Suo, C., Yücel, M., Rogasch, N. C., & Coxon, J. P. (2021) · Neuroimage Reports · doi:10.1016/j.ynirp.2021.100049 · Cited by 5 · see citing works
Guggisberg, A. G., Siebner, H. R., Lundell, H., Madsen, M. A. J., Madsen, K. H., Wiggermann, V., Mégevand, P., Proix, T., Dalal, S. S., Grouiller, F., et al. (2025) · Clinical Neurophysiology · doi:10.1016/j.clinph.2025.2110942 · Cited by 4 · see citing works
Restoring Vision with Noninvasive Brain Stimulation: A Narrative Review
Duan, X., Zhou, Y., Zhang, P., Wen, W., & Zhao, C. (2025) · Ophthalmology and Therapy · doi:10.1007/s40123-025-01249-1 · Cited by 3 · see citing works
Moretti, J., Marinovic, W., Harvey, A., Rodger, J., & Visser, T. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.903977 · Cited by 3 · see citing works
Thapa, T., Hendrikse, J. J., Thompson, S. C. H., Suo, C., Biabani, M., Morrow, J., Hoy, K. E., Fitzgerald, P. B., Fornito, A., & Rogasch, N. C. (2021) · Neuroimage Reports · doi:10.1016/j.ynirp.2021.100061 · Cited by 2 · see citing works
The Value of Neuroimaging for Treating Depression with Brain Stimulation
Sarrazin, V., & O’Shea, J. (2021) · Springer eBooks · doi:10.1007/978-3-030-76136-3_10 · Cited by 1 · see citing works
Abellaneda‐Pérez, K., Vaqué‐Alcázar, L., Perellón‐Alfonso, R., Solé‐Padullés, C., Bargalló, N., Salvador, R., Ruffini, G., Nitsche, M. A., Pascual‐Leone, Á., & David Bartrés-faz, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.15.090860 · Cited by 1 · see citing works
Self-citationTranscranial Brain Stimulation and Magnetic Resonance Spectroscopy
Stagg, C. J. (2022) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780198832256.013.24
Magnetic Resonance Spectroscopic Imaging of Brain Plasticity
Li, Y., Li, Y., & Liang, Z. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197677131.013.17
Nencha, U., & Hummel, F. C. (2025) · Clinical and Translational Neuroscience · doi:10.3390/ctn9030043
Chen, J., Li, J., Ran, L., Li, K., & Xie, Y. (2026) · Journal of Molecular Neuroscience · doi:10.1007/s12031-026-02535-8
Wang, J., Fu, X., Liu, J., & Yang, Y. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1842455
- Authors
- Vidal-Piñeiro, D., Martín-Trias, P., Falcón, C., Bargalló, N., Clemente, I. C., Valls-Solé, J., Junqué, C., Pascual-Leone, A., & Bartrés-Faz, D.
- Affiliations
- Universitat de Barcelona (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Hospital Clínic de Barcelona (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Venue
- Brain Stimulation
- Publisher
- Elsevier BV
- Published
- 2015-09
- Volume
- 8
- Issue
- 5
- Pages
- 937-944
- ISSN
- 1876-4754 (ISSN-L)
- 1935-861X
- OpenAlex
- W2085399112
- Cited by
- 49
- References
- 87
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 4 · 2022: 8 · 2021: 9 · 2020: 6 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 1 · 2015: 1
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- green
- doaj.org
- Licence
- Locations
- Brain stimulation (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Spanish Ministerio de Economia y Competitividad (PSI2012-38257)
- National Institutes of Health (UL1 RR025758)
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Keywords
- default mode network, posteromedial cortex, transcranial magnetic stimulation, theta burst stimulation, glutamate, glutamine, GABA, neurochemical modulation, synaptic plasticity, intrinsic functional connectivity, inferior parietal lobule, resting-state functional connectivity, brain connectivity
- MeSH terms
- Female, gamma-Aminobutyric Acid, Humans, Male, Parietal Lobe, Theta Rhythm, Glutamic Acid, Transcranial Magnetic Stimulation, Young Adult, Connectome
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