Chromatin modifications and their function
Kouzarides, Tony·2007·Cell
Cited by (1,104)
Items 301–400 of 1,104
- Transcriptional and epigenetic regulation of macrophages in atherosclerosisTatyana Kuznetsova, Koen H.M. Prange, Christopher K. Glass, Menno P.J. de Winther · 2019 · Nature Reviews Cardiology
- Epigenetics and Bacterial InfectionsHélène Bierne, Mélanie Anne Hamon, Pascale Cossart · 2012 · Cold Spring Harbor Perspectives in Medicine
- OPERating ON Chromatin, a Colorful Language where Context MattersKathryn E. Gardner, C. David Allis, Brian D. Strahl · 2011 · Journal of Molecular Biology
- An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and CarcinogenesisXuefeng Ren, Cliona M. McHale, Christine F. Skibola, Allan H. Smith, Martyn T. Smith, Luoping Zhang · 2010 · Environmental Health Perspectives
- The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post‐Darwinian biology?Sui Huang · 2011 · BioEssays
- Expanding the chemical toolbox for the synthesis of large and uniquely modified proteinsSomasekhar Bondalapati, Muhammad Jbara, Ashraf Brik · 2016 · Nature Chemistry
- SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell stateSteve Bilodeau, Michael H. Kagey, Garrett Michael Frampton, Peter B. Rahl, Richard A. Young · 2009 · Genes & Development
- The functional role of long non-coding RNAs and epigeneticsJinneng Cao · 2014 · Biological Procedures Online
- Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulationMarc A. Morgan, Ali Shilatifard · 2020 · Nature Genetics
- Achieving clinical success with BET inhibitors as anti-cancer agentsTatiana Shorstova, William D. Foulkes, Michael Witcher · 2021 · British Journal of Cancer
- Designer proteins: applications of genetic code expansion in cell biologyLloyd Davis, Jason W. Chin · 2012 · Nature Reviews Molecular Cell Biology
- Histone H3 lysine 4 (H3K4) methylation in development and differentiationJoel C. Eissenberg, Ali Shilatifard · 2009 · Developmental Biology
- Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyondAchim Breiling, Frank Lyko · 2015 · Epigenetics & Chromatin
- Clinical Toxicities of Histone Deacetylase InhibitorsSubramanian, Srividya, Bates, Susan E., Wright, John J., Espinoza-Delgado, Igor, Piekarz, Richard L. · 2010 · Pharmaceuticals
- Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylationAntonis Kirmizis, Helena Santos-Rosa, Christopher J. Penkett, Michael A. Singer, Michiel Vermeulen, Matthias Mann, Jürg Bähler, Roland D. Green, Tony Kouzarides · 2007 · Nature
- Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory GenesLi, Yan, Reddy, Marpadga A., Miao, Feng, Shanmugam, Narkunaraja, Yee, Jiing-Kuan, Hawkins, David, Ren, Bing, Natarajan, Rama · 2008 · Journal of Biological Chemistry
- Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and HumansZhang, Tie Yuan, Labonté, Benoit, Wen, Xiang Lan, Turecki, Gustavo, Meaney, Michael J · 2013 · Neuropsychopharmacology
- Chromatin repressive complexes in stem cells, development, and cancerLaugesen, Anne, Helin, Kristian · 2014 · Cell stem cell
- Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenanceValentina Migliori, Julius Müller, Sameer Phalke, Diana H. P. Low, Marco Bezzi, Wei Chuen Mok, Sanjeeb Kumar Sahu, Jayantha Gunaratne, Paola Capasso, Christian Bassi et al. · 2012 · Nature Structural & Molecular Biology
- Partitioning of Histone H3-H4 Tetramers During DNA Replication–Dependent Chromatin AssemblyMo Xu, Chengzu Long, Xiuzhen Chen, Chang Huang, She Chen, Bing Zhu · 2010 · Science
- Advances in early kidney specification, development and patterningGregory R. Dressler · 2009 · Development
- The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndromeAlex J. Kuo, Jikui Song, Peggie Cheung, Satoko Ishibe-Murakami, Sayumi Yamazoe, James Chen, Dinshaw J. Patel, Or Gozani · 2012 · Nature
- Screen for DNA‐damage‐responsive histone modifications identifies H3K9Ac and H3K56Ac in human cellsTjeertes, Jorrit V, Miller, Kyle M, Jackson, Stephen P · 2009 · The EMBO Journal
- Protein lysine methyltransferase G9a acts on non-histone targetsRathert, Philipp, Dhayalan, Arunkumar, Murakami, Marie, Zhang, Xing, Tamas, Raluca, Jurkowska, Renata, Komatsu, Yasuhiko, Shinkai, Yoichi, Cheng, Xiaodong, Jeltsch, Albert · 2008 · Nature Chemical Biology
- H2B Ubiquitylation Plays a Role in Nucleosome Dynamics during Transcription ElongationAlastair B. Fleming, Cheng-Fu Kao, Cory Hillyer, Michael J. Pikaart, Mary Ann Osley · 2008 · Molecular Cell
- Single-cell chromatin modification profiling reveals increased epigenetic variations with agingCheung, Peggie, Vallania, Francesco, Warsinske, Hayley C., Donato, Michele, Schaffert, Steven, Chang, Sarah E., Dvorak, Mai, Dekker, Cornelia L., Davis, Mark M., Utz, Paul J. et al. · 2018 · Cell
- An epigenetic view of plant cells cultured in vitro: Somaclonal variation and beyondMiguel, C., Marum, L. · 2011 · Journal of Experimental Botany
- Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteinsWilliam Wirt Lockwood, Kreshnik Zejnullahu, James E. Bradner, HAROLD E. VARMUS · 2012 · Proceedings of the National Academy of Sciences
- The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin StatesJoana Sequeira‐Mendes, Irene Aragüez, Ramón Peiró‐Pastor, Raúl Méndez-Giráldez, Xiaoyu Zhang, Steven E. Jacobsen, Ugo Bastolla, Crisanto Gutiérrez · 2014 · The Plant Cell
- Modern epigenetics methods in biological researchYuanyuan Li · 2020 · Methods
- The Role of Histone Acetylation in Memory Formation and Cognitive ImpairmentsLucı́a Peixoto, Ted G. Abel · 2012 · Neuropsychopharmacology
- The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIFSophie Beyer, Malene M. Kristensen, Kim Steen Jensen, Jens Vilstrup Johansen, Peter Staller · 2008 · Journal of Biological Chemistry
- Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cellsRam, Oren, Goren, Alon, Amit, Ido, Shoresh, Noam, Yosef, Nir, Ernst, Jason, Kellis, Manolis, Gymrek, Melissa, Issner, Robbyn, Coyne, Michael et al. · 2011 · Cell
- Reversible methylation of promoter-bound STAT3 by histone-modifying enzymesYang, Jinbo, Huang, Jing, Dasgupta, Maupali, Sears, Nathan, Miyagi, Masaru, Wang, Benlian, Chance, Mark R., Chen, Xing, Du, Yuping, Wang, Yuxin et al. · 2010 · Proceedings of the National Academy of Sciences
- H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage CommitmentMenno P. Creyghton, Styliani Markoulaki, Stuart S. Levine, Jacob H. Hanna, Michael A. Lodato, Ky Sha, Richard A. Young, Rudolf Jaenisch, Laurie A. Boyer · 2008 · Cell
- Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutritionLynnette Robyn Ferguson, Helen Chen, Andrew Richard Collins, Marisa Connell, Giovanna L.M. Damia, Santanu Dasgupta, Meenakshi Malhotra, Alan Keith Meeker, Amedeo Amedei, Amr Amin et al. · 2015 · Seminars in Cancer Biology
- Functional cooperation between HP1 and DNMT1 mediates gene silencingAndrea Smallwood, Pierre‐Olivier Estève, Sriharsa Pradhan, Michael Carey · 2007 · Genes & Development
- Diet induced epigenetic changes and their implications for healthJill A. McKay, John Cummings Mathers · 2011 · Acta Physiologica
- Regulation of gene transcription by Polycomb proteinsSergi Aranda, Glòria Mas Martín, Luciano Di Croce · 2015 · Science Advances
- Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell IdentityZhang, Jingli A., Mortazavi, Ali, Williams, Brian A., Wold, Barbara J., Rothenberg, Ellen V. · 2012 · Cell
- Discovery and Characterization of Small Molecule Inhibitors of the BET Family BromodomainsChun‐wa Chung, Hervé Coste, Julia H. M. White, Olivier Mirguet, Jonathan I. Wilde, Romain L. Gosmini, C. J. Delves, Sylvie Demaria Magny, Robert Woodward, Stephen A. Hughes et al. · 2011 · Journal of Medicinal Chemistry
- The future of epigenetic therapy in solid tumours—lessons from the pastNilofer Saba Azad, Cynthia A. Zahnow, Charles M. Rudin, Stephen B. Baylin · 2013 · Nature Reviews Clinical Oncology
- Epigenetic Reprogramming in Mammalian DevelopmentKonstantin Lepikhov, Julia Arand, Mark Wossidlo, Joern Walter · 2012 · Encyclopedia of Molecular Cell Biology and Molecular Medicine
- Fast signals and slow marks: the dynamics of histone modificationsTeresa K. Barth, Axel Imhof · 2010 · Trends in Biochemical Sciences
- Genome-Wide Association of Histone H3 Lysine Nine Methylation with CHG DNA Methylation in Arabidopsis thalianaBernatavichute, Yana V., Zhang, Xiaoyu, Cokus, Shawn, Pellegrini, Matteo, Jacobsen, Steven E. · 2008 · PLoS ONE
- Epigenetic control of myeloid cell differentiation, identity and functionDamiana Álvarez‐Errico, Roser Vento‐Tormo, Michael H. Sieweke, Esteban Ballestar · 2014 · Nature reviews. Immunology
- GlcNAcylation of histone H2B facilitates its monoubiquitinationRyoji Fujiki, Waka Hashiba, Hiroki Sekine, Atsushi Yokoyama, Toshihiro Chikanishi, Saya Ito, Yuuki Imai, Jaehoon Kim, Housheng Hansen He, Katsuhide Igarashi et al. · 2011 · Nature
- BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine DesignCamila Covián, Ayleen Fernández‐Fierro, Angello R Retamal-Díaz, Fabián E. Díaz, Abel Eduardo Vasquez, Margarita K. Lay, Claudia A. Riedel, Pablo A. González, Susan M. Bueno, Alexis M. Kalergis · 2019 · Frontiers in Immunology
- A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric ComplexFritsch, Lauriane, Robin, Philippe, Mathieu, Jacques R.R., Souidi, Mouloud, Hinaux, Hélène, Rougeulle, Claire, Harel-Bellan, Annick, Ameyar-Zazoua, Maya, Ait-Si-Ali, Slimane · 2010 · Molecular Cell
- The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagyJens Füllgrabe, Melinda A. Lynch-Day, Nina Heldring, Wenbo Li, Robin B. Struijk, Qi Ma, Ola Hermanson, Michael G. Rosenfeld, Daniel J. Klionsky, Bertrand Joseph · 2013 · Nature
- Genome-wide Analysis of Histone Methylation Reveals Chromatin State-Based Regulation of Gene Transcription and Function of Memory CD8+ T CellsYasuto Araki, Zhibin Wang, Chongzhi Zang, William H. Wood, Dustin E. Schones, Kairong Cui, Tae‐Young Roh, Brad Lhotsky, Robert P. Wersto, Weiqun Peng et al. · 2009 · Immunity
- The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in HumansJaime L. Miller, Patrick A. Grant · 2012 · Sub-cellular biochemistry/Subcellular biochemistry
- Targeting DNA methylation for epigenetic therapyXiaojing Yang, Fides D. Lay, Han Han, Peter A. Jones · 2010 · Trends in Pharmacological Sciences
- Histone modifying enzymes: Structures, mechanisms, and specificitiesRonen Marmorstein, Raymond C. Trievel · 2008 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of ProteinsChao Xu, Ke Liu, Hazem Ahmed, P. Loppnau, Matthieu Schapira, Jinrong Min · 2015 · Journal of Biological Chemistry
- Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogrammingMargaret E. McLaughlin-Drubin, Christopher P. Crum, Karl Münger · 2011 · Proceedings of the National Academy of Sciences
- Drug Discovery Targeting Bromodomain-Containing Protein 4Zhiqing Liu, Pingyuan Wang, Haiying Chen, Eric A. Wold, Bing Tian, Allan R. Brasier, Jia Zhou · 2017 · Journal of Medicinal Chemistry
- Environmental epigenetics in metal exposureRicardo Iván Martínez‐Zamudio, Hyo Chol Ha · 2011 · Epigenetics
- Molecular Regulation of H3K4 Trimethylation by Wdr82, a Component of Human Set1/COMPASSMin Wu, Peng Fei Wang, Jung Shin Lee, Skylar Martin‐Brown, Laurence A. Florens, Michael P. Washburn, Ali Shilatifard · 2008 · Molecular and Cellular Biology
- Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approachBao, Xiucong, Wang, Yi, Li, Xin, Li, Xiao-Meng, Liu, Zheng, Yang, Tangpo, Wong, Chi Fat, Zhang, Jiangwen, Hao, Quan, Li, Xiang David · 2014 · eLife
- Role of HDAC2 in the Pathophysiology of COPDPeter John Barnes · 2008 · Annual Review of Physiology
- EpCAM in carcinogenesis: the good, the bad or the uglyBernardina T.F. van der Gun, Lieuwe J. Melchers, Marcel H.J. Ruiters, L.F.M.H. de Leij, P. M. McLaughlin, Marianne G. Rots · 2010 · Carcinogenesis
- Nuclear Reprogramming in CellsJ. Gurdon, D. A. Melton · 2008 · Science
- Physical exercise as an epigenetic modulator of brain plasticity and cognitionJansen Fernandes, Ricardo Mário Arida, Fernando Gómez‐Pinilla · 2017 · Neuroscience & Biobehavioral Reviews
- Epigenetic inheritance uncoupled from sequence-specific recruitmentKaushik Ragunathan, Gloria T. Jih, Danesh Moazed · 2014 · Science
- Reprogramming cell fates: reconciling rarity with robustnessSui Huang · 2009 · BioEssays
- Beyond Gene Discovery in Inflammatory Bowel Disease: The Emerging Role of EpigeneticsNicholas T. Ventham, Nicholas Alexander Kennedy, Elaine R. Nimmo, Jack Satsangi · 2013 · Gastroenterology
- Diabetic nephropathy—emerging epigenetic mechanismsMitsuo V. Kato, Rama D Natarajan · 2014 · Nature Reviews Nephrology
- Dimethylation of H3K4 by Set1 Recruits the Set3 Histone Deacetylase Complex to 5′ Transcribed RegionsTae Soo Kim, Stephen Buratowski · 2009 · Cell
- Histone acetyl transferases as emerging drug targetsFrank J. Dekker, Hidde J. Haisma · 2009 · Drug Discovery Today
- Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and diseaseAlbert E. Almada, Amy J. Wagers · 2016 · Nature Reviews Molecular Cell Biology
- Inhibitors of Protein Methyltransferases and DemethylasesH. Ümit Kanıskan, Michael L. Martini, Jian Jun Jin · 2017 · Chemical Reviews
- DNA methylomes, histone codes and miRNAs: Tying it all togetherSònia Guil, Manel Esteller · 2008 · The International Journal of Biochemistry & Cell Biology
- An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EEDQi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling et al. · 2017 · Nature Chemical Biology
- Helper T cell diversity and plasticityShingo Nakayamada, Hayato Takahashi, Yuka Kanno, John J. O’Shea · 2012 · Current Opinion in Immunology
- Readout of Epigenetic ModificationsDinshaw J. Patel, Zhanxin Wang · 2013 · Annual Review of Biochemistry
- Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)Man Mohan, Hans‐Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P. Washburn, Laurence A. Florens, Ali Shilatifard · 2010 · Genes & Development
- Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndromeGabriel E. Zentner, Wanda S. Layman, Donna M. Martin, Peter C. Scacheri · 2010 · American Journal of Medical Genetics Part A
- Genome-Wide and Organ-Specific Landscapes of Epigenetic Modifications and Their Relationships to mRNA and Small RNA Transcriptomes in MaizeXiangfeng Wang, Axel A. Elling, Xueyong Li, Ning Li, Zhiyu Peng, Guangming He, Hui Sun, Yijun Qi, X. Shirley Liu, Xing Wang Deng · 2009 · The Plant Cell
- SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repairMcCord, Ronald A., Michishita, Eriko, Hong, Tao, Berber, Elisabeth, Boxer, Lisa D., Kusumoto, Rika, Guan, Shenheng, Shi, Xiaobing, Gozani, Or, Burlingame, Alma L. et al. · 2009 · Aging
- Vitamin D and the epigenomeFetahu, Irfete S., Höbaus, Julia, Kállay, EnikÅ‘ · 2014 · Frontiers in Physiology
- Dynamic Changes in Chromatin Accessibility Occur in CD8 + T Cells Responding to Viral InfectionJames P Scott-Browne, Isaac F. López-Moyado, Sara Trifari, Victor Wong, Lukas Chávez, Anjana Rao, Renata M. Pereira · 2016 · Immunity
- Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor ComplexSchaefer, Anne, Sampath, Srihari C., Intrator, Adam, Min, Alice, Gertler, Tracy S., Surmeier, D. James, Tarakhovsky, Alexander, Greengard, Paul · 2009 · Neuron
- Suppression of the antiviral response by an influenza histone mimicIvan Marazzi, Jessica Ho, Jaehoon Kim, Balaji Manicassamy, Scott B. Dewell, Randy A. Albrecht, Christopher W. Seibert, Uwe Schaefer, Kate L. Jeffrey, Rab K. Prinjha et al. · 2012 · Nature
- CpG Islands Recruit a Histone H3 Lysine 36 DemethylaseNeil P. Blackledge, Jinchuan Zhou, Michael Yevgeniy Tolstorukov, Anca M. Farcas, Peter J. Park, Robert J. Klose · 2010 · Molecular Cell
- Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiologyRudolf P. Talens, Dorret Irene Boomsma, Elmar W. Tobi, Dennis Kremer, J. Wouter Jukema, Gonneke A. H. M. Willemsen, Hein Putter, P. Eline Slagboom, Bastiaan T. Heijmans · 2010 · The FASEB Journal
- 30 nm Chromatin Fibre Decompaction Requires both H4-K16 Acetylation and Linker Histone EvictionPhilip J. J. Robinson, Woojin An, Andrew L. Routh, Fabrizio Martino, Lynda Chapman, Robert G. Roeder, Daniela Rhodes · 2008 · Journal of Molecular Biology
- Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET BromodomainsOlivier Mirguet, Romain L. Gosmini, Jérôme Toum, Catherine A. Clément, Mélanie Barnathan, Jean-Marie G. Brusq, Jacqueline E. Mordaunt, Richard M. Grimes, Miriam C. Crowe, Olivier Pineau et al. · 2013 · Journal of Medicinal Chemistry
- Combined Action of PHD and Chromo Domains Directs the Rpd3S HDAC to Transcribed ChromatinBing Li, Madelaine Gogol, Mike Carey, Daeyoup Lee, Chris W. Seidel, Jerry L. Workman · 2007 · Science
- Eukaryotic transcriptional dynamics: from single molecules to cell populationsCoulon, Antoine, Chow, Carson C., Singer, Robert H., Larson, Daniel R. · 2013 · Nature Reviews Genetics
- Protein Acetylation Microarray Reveals that NuA4 Controls Key Metabolic Target Regulating GluconeogenesisYu-Yi Lin, Jin‐Ying Lu, Junmei Zhang, Wendy Walter, Weiwei Dang, Jun Wan, Sheng‐ce Tao, Jiang X. Qian, Yingming Zhao, Jef D. Boeke et al. · 2009 · Cell
- Epigenetic codes in cognition and behaviourJohannes Gräff, Isabelle M. Mansuy · 2008 · Behavioural Brain Research
- Homocysteine Modification in Protein Structure/Function and Human DiseaseHieronim Jakubowski · 2018 · Physiological Reviews
- Transgenerational epigenetic inheritance: More questions than answersLucia Daxinger, Emma Whitelaw · 2010 · Genome Research
- Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal DifferentiationShukla, Surabhi, Tekwani, Babu L. · 2020 · Frontiers in Pharmacology
- Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain developmentRusty L. Montgomery, Jenny Hsieh, Ana Carolina Coutinho Barbosa, James A. Richardson, Eric N. Olson · 2009 · Proceedings of the National Academy of Sciences
- CRISPR/Cas9-based engineering of the epigenomePulecio, Julian, Verma, Nipun, Mejía-Ramírez, Eva, Huangfu, Danwei, Raya, Angel · 2017 · Cell Stem Cell
- Histone onco-modificationsJens Füllgrabe, Edel T. Kavanagh, Bertrand Joseph · 2011 · Oncogene
- Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene ResponsesVineet D. Menachery, Amie J. Eisfeld, Alexandra Schäfer, Laurence Josset, Amy María Sims, Sean C Proll, Shufang Fan, Chengjun Li, Gabriele Neumann, Susan C. Tilton et al. · 2014 · mBio
- The role of nuclear architecture in genomic instability and ageing.Oberdoerffer, Philipp, Sinclair, David A. · 2007 · Nature Reviews Molecular Cell Biology