Chromatin modifications and their function

Kouzarides, Tony·2007·Cell

Cited by (1,104)

Items 101–200 of 1,104

  1. Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
    Frank W. Schmitges, Archana Bairavasundaram Prusty, Mahamadou Faty, Alexandra Stützer, Gondichatnahalli M. Lingaraju, Jonathan Aiwazian, Ragna Sack, Daniel Heß, Ling Li, Shaolian Zhou et al. · 2011 · Molecular Cell
  2. Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
    Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin · 2010 · Neuropsychopharmacology
  3. Interpreting the language of histone and DNA modifications
    Scott B. Rothbart, Brian D. Strahl · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  4. A model for transmission of the H3K27me3 epigenetic mark
    Klaus H. Hansen, Adrian P. Bracken, Diego Pasini, Nikolaj Dietrich, Simmi S. Gehani, Astrid Monrad, Juri Rappsilber, Mads Lerdrup, Kristian Helin · 2008 · Nature Cell Biology
  5. Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
    Aleksey G. Kazantsev, Leslie Michels Thompson · 2008 · Nature Reviews Drug Discovery
  6. The landscape of accessible chromatin in mammalian preimplantation embryos
    Jing-Yi Wu, Bo Huang, He Chen, Qiang-Zong Yin, Yang Liu, Yun-Long Xiang, Bingjie Zhang, Bo-Feng Liu, Qiu-Jun Wang, Weikun Xia et al. · 2016 · Nature
  7. Integrative epigenomic mapping defines four main chromatin states in Arabidopsis
    François Roudier, Ikhlak Ahmed, Caroline Bérard, Alexis Sarazin, Tristan Mary‐Huard, Sandra Cortijo, Daniel Bouyer, Erwann Caillieux, Evelyne Duvernois‐Berthet, Liza Al-Shikhley et al. · 2011 · The EMBO Journal
  8. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
    Sunhwa Hong, Young‐Wook Cho, Li‐Rong Yu, Hong Yu, Timothy D. Veenstra, Kai Ge · 2007 · Proceedings of the National Academy of Sciences
  9. Allelic reprogramming of the histone modification H3K4me3 in early mammalian development
    Bingjie Zhang, Hui Zheng, Bo Huang, Wenzhi Li, Yun-Long Xiang, Xu Peng, Ming Jia, Xiaotong Wu, Yu Zhang, Qian-Hua Xu et al. · 2016 · Nature
  10. Genetic landscape of esophageal squamous cell carcinoma
    Yibo Gao, Zhao-li Chen, Jia-Gen Li, Xue-Da Hu, Xue-Jiao Shi, Zeng-Miao Sun, Fan Zhang, Zi-Ran Zhao, Zi-Tong Li, Zi-Yuan Liu et al. · 2014 · Nature Genetics
  11. Structure and Function of Mammalian DNA Methyltransferases
    Renata Zofia Jurkowska, Tomasz Piotr Jurkowski, Albert Jeltsch · 2010 · ChemBioChem
  12. Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
    Madhusoodanan Mottamal, Shilong Zheng, Tien L. Huang, Guangdi Wang · 2015 · Molecules
  13. DNA methylation: The nuts and bolts of repression
    Tina Branscombe Miranda, Peter A. Jones · 2007 · Journal of Cellular Physiology
  14. Covalent modifications of histones during development and disease pathogenesis
    Sukesh R. Bhaumik, Edwin R. Smith, Ali Shilatifard · 2007 · Nature Structural & Molecular Biology
  15. Epigenetic control of T-helper-cell differentiation
    Christopher B. Wilson, Emily A. Rowell, Masayuki Sekimata · 2009 · Nature reviews. Immunology
  16. Histone acetylation: molecular mnemonics on the chromatin
    Gräff, Johannes, Tsai, Li-Huei · 2013 · Nature Reviews Neuroscience
  17. Chromatin marks identify critical cell types for fine mapping complex trait variants
    Trynka, Gosia, Sandor, Cynthia, Han, Buhm, Xu, Han, Stranger, Barbara E, Liu, X Shirley, Raychaudhuri, Soumya · 2013 · Nature Genetics
  18. Epigenetic regulation of aging: implications for interventions of aging and diseases
    Wang Kang, Huicong Liu, Qinchao Hu, Lingna Wang, Jiaqing Liu, Zikai Zheng, Weiqi Zhang, Jie Ren, Fangfang Zhu, Guang‐Hui Liu · 2022 · Signal Transduction and Targeted Therapy
  19. Differential chromatin marking of introns and expressed exons by H3K36me3
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  20. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
    Paul A. Cloos, Jesper Christensen, Karl Agger, Kristian Helin · 2008 · Genes & Development
  21. The Notch signaling pathway: Transcriptional regulation at Notch target genes
    Tilman Borggrefe, Franz Oswald · 2009 · Cellular and Molecular Life Sciences
  22. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
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  23. Amino Assets: How Amino Acids Support Immunity
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  24. Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation
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  25. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
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  26. Chromatin organization marks exon-intron structure
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  27. Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs
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  28. Lysine succinylation and lysine malonylation in histones
    Xie, Zhongyu, Dai, Junbiao, Dai, Lunzhi, Tan, Minjia, Cheng, Zhongyi, Wu, Yeming, Boeke, Jef D., Zhao, Yingming · 2012 · Molecular & Cellular Proteomics
  29. Histone phosphorylation
    Dorine Rossetto, Nikita Avvakumov, Jacques Côté · 2012 · Epigenetics
  30. Epigenetics: a molecular link between environmental factors and type 2 diabetes
    Ling, Charlotte, Groop, Leif · 2009 · Diabetes
  31. Child Health, Developmental Plasticity, and Epigenetic Programming
    Ze’ev Hochberg, Robert Feil, Miguel Constância, Mario F. Fraga, Claudine Junien, Jean‐Claude Carel, Pascal Boileau, Yves Le Bouc, Cheri Deal, Karen A. Lillycrop et al. · 2010 · Endocrine Reviews
  32. Readers of histone modifications
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  33. JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin
    Mark A. Dawson, Andrew J. Bannister, Berthold Göttgens, Samuel D. Foster, Till Bartke, Anthony Richard Green, Tony Kouzarides · 2009 · Nature
  34. A complete immunoglobulin gene is created by somatic recombination
    Christine Brack, Minoru Hirama, Rita Lenhard-Schuller, Susumu Tonegawa · 1978 · Cell
  35. Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
    María Berdasco, Manel Esteller · 2010 · Developmental Cell
  36. H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy
    Monika Podhorecka, Andrzej Składanowski, Przemyslaw M. Bozko · 2010 · Journal of Nucleic Acids
  37. Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation
    Bartke, Till, Vermeulen, Michiel, Xhemalce, Blerta, Robson, Samuel C., Mann, Matthias, Kouzarides, Tony · 2010 · Cell
  38. Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
    Ahel, Dragana, Hořejší, Zuzana, Wiechens, Nicola, Polo, Sophie E., Garcia-Wilson, Elisa, Ahel, Ivan, Flynn, Helen, Skehel, Mark, West, Stephen C., Jackson, Stephen P. et al. · 2009 · Science
  39. Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
    Mitsuo V. Kato, Rama D Natarajan · 2019 · Nature Reviews Nephrology
  40. The diverse functions of Dot1 and H3K79 methylation
    Anh Tram Nguyen, Yi Zhang · 2011 · Genes & Development
  41. The Adult Ventricular–Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis
    Lim, Daniel A., Alvarez-Buylla, Arturo · 2016 · Cold Spring Harbor Perspectives in Biology
  42. Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli
    Renthal, William, Maze, Ian, Krishnan, Vaishnav, Covington, Herbert E., Xiao, Guanghua, Kumar, Arvind, Russo, Scott J., Graham, Ami, Tsankova, Nadia, Kippin, Tod E. et al. · 2007 · Neuron
  43. Genetically encoding Nε-acetyllysine in recombinant proteins
    Heinz Neumann, Sew‐Yeu Peak‐Chew, Jason W. Chin · 2008 · Nature Chemical Biology
  44. Chromatin replication and epigenome maintenance
    Constance Alabert, Anja Groth · 2012 · Nature Reviews Molecular Cell Biology
  45. Next-generation genomics: an integrative approach
    R. David Hawkins, Gary C. Hon, Bing Ren · 2010 · Nature Reviews Genetics
  46. Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
    Rocío G. Urdinguio, Jose Vicente Sanchez-Mut, Manel Esteller · 2009 · The Lancet Neurology
  47. Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models
    Miriam Fanjul‐Fernández, Alicia R. Folgueras, Sandra Cabrera, Carlos López-Otı́n · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  48. Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation
    McGinty, Robert K., Kim, Jaehoon, Chatterjee, Champak, Roeder, Robert G., Muir, Tom W. · 2008 · Nature
  49. DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs
    Karimi, Mohammad M., Goyal, Preeti, Maksakova, Irina A., Bilenky, Misha, Leung, Danny, Tang, Jie Xin, Shinkai, Yoichi, Mager, Dixie L., Jones, Steven, Hirst, Martin et al. · 2011 · Cell Stem Cell
  50. Epigenetic regulation of centromeric chromatin: old dogs, new tricks?
    Robin C. Allshire, Gary H. Karpen · 2008 · Nature Reviews Genetics
  51. The Tubulin Code
    Verhey, Kristen J., Gaertig, Jacek · 2007 · Cell Cycle
  52. Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging
    Liu, Ling, Cheung, Tom H., Charville, Gregory W., Hurgo, Bernadette Marie Ceniza, Leavitt, Tripp, Shih, Johnathan, Brunet, Anne, Rando, Thomas A. · 2013 · Cell Reports
  53. Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils
    Indira Neeli, Salar N. Khan, Marko Z. Radic · 2008 · The Journal of Immunology
  54. Global Epigenetic and Transcriptional Trends among Two Rice Subspecies and Their Reciprocal Hybrids
    Guangming He, Xiaopeng Zhu, Axel Armin Elling, Liangbi Chen, Xiangfeng Wang, Lan Ping Guo, Manzhong Liang, Hang He, Huiyong Zhang, Fangfang Chen et al. · 2010 · The Plant Cell
  55. Epigenetic modifications of histones in cancer
    Zibo Zhao, Ali Shilatifard · 2019 · Genome biology
  56. Mapping Human Epigenomes
    Rivera, Chloe M., Ren, Bing · 2013 · Cell
  57. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
    Zhao, Chunnian, Sun, GuoQiang, Li, Shengxiu, Shi, Yanhong · 2009 · Nature Structural & Molecular Biology
  58. Epigenetic modifications in cancer
    Rajnee Kanwal, Sanjay Gupta · 2011 · Clinical Genetics
  59. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
    Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu, Sylvie Rival‐Gervier, Abdellah Allali‐Hassani, Viviane Labrie, Tim J. Wigle, Peter A. DiMaggio, Gregory A. Wasney, Alena Siarheyeva et al. · 2011 · Nature Chemical Biology
  60. Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation
    Edmunds, John W, Mahadevan, Louis C, Clayton, Alison L · 2008 · The EMBO Journal
  61. Deconstructing repression: evolving models of co-repressor action
    Perissi, Valentina, Jepsen, Kristen, Glass, Christopher K., Rosenfeld, Michael G. · 2010 · Nature Reviews Genetics
  62. Glioma epigenetics: From subclassification to novel treatment options
    Olga Gusyatiner, Monika E. Hegi · 2017 · Seminars in Cancer Biology
  63. Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders
    Frank V. Brozovich, Christopher Nicholson, Chantal Vanessa Degen, Yuan Z. Gao, Manoj Aggarwal, Kathleen G. Morgan · 2016 · Pharmacological Reviews
  64. H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation
    Wen Yuan, Mo Xu, Chang Huang, Nan Liu, She Chen, Bing Zhu · 2011 · Journal of Biological Chemistry
  65. The impact of cellular metabolism on chromatin dynamics and epigenetics
    Reid, Michael A., Dai, Ziwei, Locasale, Jason W. · 2017 · Nature Cell Biology
  66. Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
    McDonald, Oliver G, Li, Xin, Saunders, Tyler, Tryggvadottir, Rakel, Mentch, Samantha J, Warmoes, Marc O, Word, Anna E, Carrer, Alessandro, Salz, Tal H, Natsume, Sonoko et al. · 2017 · Nature Genetics
  67. Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy
    Li, Qing, Geng, Shan, Luo, Hao, Wang, Wei, Mo, Ya-Qi, Luo, Qing, Wang, Lu, Song, Guan-Bin, Sheng, Jian-Peng, Xu, Bo · 2024 · Signal Transduction and Targeted Therapy
  68. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
    Yang, Liuqing, Lin, Chunru, Liu, Wen, Zhang, Jie, Ohgi, Kenneth A., Grinstein, Jonathan D., Dorrestein, Pieter C., Rosenfeld, Michael G. · 2011 · Cell
  69. Manipulation of host-cell pathways by bacterial pathogens
    Amit P. Bhavsar, Julian A. Guttman, B. Brett Finlay · 2007 · Nature
  70. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
    Min, Sang-Won, Chen, Xu, Tracy, Tara E, Li, Yaqiao, Zhou, Yungui, Wang, Chao, Shirakawa, Kotaro, Minami, S Sakura, Defensor, Erwin, Mok, Sue Ann et al. · 2015 · Nature Medicine
  71. Crosstalk between histone modifications during the DNA damage response
    Haico van Attikum, Susan M. Gasser · 2009 · Trends in Cell Biology
  72. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
    Yuin‐Han Loh, Weiwei Zhang, Xi Chen, Joshy George, Huck‐Hui Ng · 2007 · Genes & Development
  73. Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity
    Karin Johanna Ferrari, Andrea Scelfo, Sriganesh Jammula, Alessandro Cuomo, Iros Barozzi, Alexandra Stützer, Wolfgang Fischle, Tiziana Bonaldi, Diego Pasini · 2013 · Molecular Cell
  74. HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation
    McQuown, Susan C., Barrett, Ruth M., Matheos, Dina P., Post, Rebecca J., Rogge, George A., Alenghat, Theresa, Mullican, Shannon E., Jones, Steven, Rusche, James R., Lazar, Mitchell A. et al. · 2011 · The Journal of Neuroscience
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  76. Global Histone Modifications in Breast Cancer Correlate with Tumor Phenotypes, Prognostic Factors, and Patient Outcome
    Somaia Elbauomy Elsheikh, Andrew R. Green, Emad A. Rakha, Des G. Powe, Rabab A. Ahmed, Hilary M. Collins, Daniele Soria, Jonathan M. Garibaldi, Claire E. Paish, Amr A. Ammar et al. · 2009 · Cancer Research
  77. Post-Translational Modifications of Histones That Influence Nucleosome Dynamics
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  78. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
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  81. Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis
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  82. Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics
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  83. Signals and Combinatorial Functions of Histone Modifications
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  85. A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation
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  93. Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
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  98. Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis
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