The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
miR-146a deficiency in mice caused autoimmunity and a hyper-reactive immune response.
“Previous studies have shown that miR-146a deficiency in mice caused autoimmunity and a hyper-reactive immune response [74].”
From The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs (2020) · cites this paper as [74]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187
Taganov, K. D., Boldin, M. P., Chang, K.-J., & Baltimore, D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605298103 · Cited by 4,317
Self-citationSakaguchi, S. (2005) · Nature Immunology · doi:10.1038/ni1178 · Cited by 2,669
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
Rubtsov, Y. P., Rasmussen, J. P., Chi, E. Y., Fontenot, J., Castelli, L., Ye, X., Treuting, P., Siewe, L., Roers, A., Henderson, W. R., et al. (2008) · Immunity · doi:10.1016/j.immuni.2008.02.017 · Cited by 1,586
Self-citationCD4 + Regulatory T Cells Control T H 17 Responses in a Stat3-Dependent Manner
Chaudhry, A., Rudra, D., Treuting, P., Samstein, R. M., Liang, Y., Kas, A., & Rudensky, A. Y. (2009) · Science · doi:10.1126/science.1172702 · Cited by 1,000
Self-citationGenome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
Zheng, Y., Josefowicz, S. Z., Kas, A., Chu, T.-T., Gavin, M. A., & Rudensky, A. Y. (2007) · Nature · doi:10.1038/nature05563 · Cited by 835
Self-citationThe Kinase Akt1 Controls Macrophage Response to Lipopolysaccharide by Regulating MicroRNAs
Androulidaki, A., Iliopoulos, D., Arranz, A., Doxaki, C., Schworer, S., Zacharioudaki, V., Margioris, A. N., Tsichlis, P. N., & Tsatsanis, C. (2009) · Immunity · doi:10.1016/j.immuni.2009.06.024 · Cited by 581
Flagged first, then by citations
Research works printed but not linked: 49
- Alexander, 1999, SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine, Cell, 98, 597, 10.1016/S0092-8674(00)80047-1 · DOI · Paper page
- Barbi, 2007, IFN-gamma and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cells, Blood, 110, 2215, 10.1182/blood-2007-03-081307 · DOI
- Beima, 2006, T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects, J. Biol. Chem., 281, 11992, 10.1074/jbc.M513613200 · DOI
- Belkaid, 2009, Regulatory T cells in the control of host-microorganism interactions (∗), Annu. Rev. Immunol., 27, 551, 10.1146/annurev.immunol.021908.132723 · DOI
- Ben-Sasson, 2009, IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation, Proc. Natl. Acad. Sci. USA, 106, 7119, 10.1073/pnas.0902745106 · DOI · Paper page
- Cameron, 2008, Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways, J. Virol., 82, 1946, 10.1128/JVI.02136-07 · DOI
- Chen, 2005, Real-time quantification of microRNAs by stem-loop RT-PCR, Nucleic Acids Res., 33, e179, 10.1093/nar/gni178 · DOI
- Chong, 2008, The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease, J. Exp. Med., 205, 2005, 10.1084/jem.20081219 · DOI
- Chung, 2009, Critical regulation of early Th17 cell differentiation by interleukin-1 signaling, Immunity, 30, 576, 10.1016/j.immuni.2009.02.007 · DOI
- Cobb, 2006, A role for Dicer in immune regulation, J. Exp. Med., 203, 2519, 10.1084/jem.20061692 · DOI
- Curtale, 2010, An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes, Blood, 115, 265, 10.1182/blood-2009-06-225987 · DOI · Paper page
- Fontenot, 2003, Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nat. Immunol., 4, 330, 10.1038/ni904 · DOI · Paper page
- Fontenot, 2005, Regulatory T cell lineage specification by the forkhead transcription factor foxp3, Immunity, 22, 329, 10.1016/j.immuni.2005.01.016 · DOI
- Gavin, 2007, Foxp3-dependent programme of regulatory T-cell differentiation, Nature, 445, 771, 10.1038/nature05543 · DOI
- Horino, 2008, Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice, Int. Immunol., 20, 753, 10.1093/intimm/dxn033 · DOI
- Hou, 2009, MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2, J. Immunol., 183, 2150, 10.4049/jimmunol.0900707 · DOI · Paper page
- Hsieh, 2006, An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires, Nat. Immunol., 7, 401, 10.1038/ni1318 · DOI
- Hu, 2009, Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases, Immunity, 31, 539, 10.1016/j.immuni.2009.09.002 · DOI · Paper page
- Huang, 2009, miR-142-3p restricts cAMP production in CD4+CD25- T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA, EMBO Rep., 10, 180, 10.1038/embor.2008.224 · DOI
- Jazdzewski, 2008, Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma, Proc. Natl. Acad. Sci. USA, 105, 7269, 10.1073/pnas.0802682105 · DOI · Paper page
- Khattri, 2003, An essential role for Scurfin in CD4+CD25+ T regulatory cells, Nat. Immunol., 4, 337, 10.1038/ni909 · DOI
- Kim, 2007, Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice, Nat. Immunol., 8, 191, 10.1038/ni1428 · DOI
- Koch, 2009, The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation, Nat. Immunol., 10, 595, 10.1038/ni.1731 · DOI · Paper page
- Kohlhaas, 2009, Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells, J. Immunol., 182, 2578, 10.4049/jimmunol.0803162 · DOI
- Kubo, 2003, Suppressors of cytokine signaling and immunity, Nat. Immunol., 4, 1169, 10.1038/ni1012 · DOI
- Lal, 2009, miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3′UTR microRNA recognition elements, Mol. Cell, 35, 610, 10.1016/j.molcel.2009.08.020 · DOI
- Lin, 2007, Regulatory T cell development in the absence of functional Foxp3, Nat. Immunol., 8, 359, 10.1038/ni1445 · DOI
- Liston, 2008, Dicer-dependent microRNA pathway safeguards regulatory T cell function, J. Exp. Med., 205, 1993, 10.1084/jem.20081062 · DOI
- Lord, 2005, T-bet is required for optimal proinflammatory CD4+ T-cell trafficking, Blood, 106, 3432, 10.1182/blood-2005-04-1393 · DOI · Paper page
- Lu, 2009, Molecular orchestration of differentiation and function of regulatory T cells, Genes Dev., 23, 1270, 10.1101/gad.1791009 · DOI
- Lu, 2009, Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein, Immunity, 30, 80, 10.1016/j.immuni.2008.11.010 · DOI
- Maitra, 2009, Differential regulation of Foxp3 and IL-17 expression in CD4 T helper cells by IRAK-1, J. Immunol., 182, 5763, 10.4049/jimmunol.0900124 · DOI
- Marine, 1999, SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality, Cell, 98, 609, 10.1016/S0092-8674(00)80048-3 · DOI
- Marson, 2007, Foxp3 occupancy and regulation of key target genes during T-cell stimulation, Nature, 445, 931, 10.1038/nature05478 · DOI · Paper page
- Meraz, 1996, Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway, Cell, 84, 431, 10.1016/S0092-8674(00)81288-X · DOI · Paper page
- Monticelli, 2005, MicroRNA profiling of the murine hematopoietic system, Genome Biol., 6, R71, 10.1186/gb-2005-6-8-r71 · DOI · Paper page
- Nakajima, 2002, Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-gamma stimulation, Eur. J. Immunol., 32, 1792, 10.1002/1521-4141(200206)32:6<1792::AID-IMMU1792>3.0.CO;2-0 · DOI
- O'Connell, 2007, MicroRNA-155 is induced during the macrophage inflammatory response, Proc. Natl. Acad. Sci. USA, 104, 1604, 10.1073/pnas.0610731104 · DOI · Paper page
- Oldenhove, 2009, Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection, Immunity, 31, 772, 10.1016/j.immuni.2009.10.001 · DOI
- Schmitz, 2005, IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines, Immunity, 23, 479, 10.1016/j.immuni.2005.09.015 · DOI
- Siebler, 2003, A key pathogenic role for the STAT1/T-bet signaling pathway in T-cell-mediated liver inflammation, Hepatology, 38, 1573
- Tanaka, 2008, Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads, J. Immunol., 180, 3746, 10.4049/jimmunol.180.6.3746 · DOI
- Tang, 2009, MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins, Arthritis Rheum., 60, 1065, 10.1002/art.24436 · DOI
- Thai, 2007, Regulation of the germinal center response by microRNA-155, Science, 316, 604, 10.1126/science.1141229 · DOI
- Williams, 2007, Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3, Nat. Immunol., 8, 277, 10.1038/ni1437 · DOI
- Zhan, 2009, SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymus, Immunol. Cell Biol., 87, 473, 10.1038/icb.2009.23 · DOI
- Zheng, 2009, Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses, Nature, 458, 351, 10.1038/nature07674 · DOI · Paper page
- Zhou, 2008, Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity, J. Exp. Med., 205, 1983, 10.1084/jem.20080707 · DOI
- Zhou, 2009, Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo, Nat. Immunol., 10, 1000, 10.1038/ni.1774 · DOI
Cited by
Sorted by citations
Regulatory T cells: mechanisms of differentiation and function
Josefowicz, S. Z., Lu, L.-F., & Rudensky, A. Y. (2012) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141623 · Cited by 2,866
Self-citationVinuesa, C. G., Linterman, M. A., Yu, D., & MacLennan, I. C. M. (2016) · Annual Review of Immunology · doi:10.1146/annurev-immunol-041015-055605 · Cited by 1,141
MicroRNAs as regulatory elements in immune system logic
Mehta, A., & Baltimore, D. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.40 · Cited by 704
Self-citationModulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
Butovsky, O., Siddiqui, S., Gabriely, G., Lanser, A. J., Dake, B., Murugaiyan, G., Doykan, C. E., Wu, P. M., Gali, R. R., Iyer, L. K., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci62636 · Cited by 481
Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K., & O'Shea, J. J. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075058 · Cited by 342
Chronic immune response dysregulation in MDS pathogenesis
Barreyro, L., Chlon, T. M., & Starczynowski, D. T. (2018) · Blood · doi:10.1182/blood-2018-03-784116 · Cited by 226
Control of inflammation by integration of environmental cues by regulatory T cells
Chaudhry, A., & Rudensky, A. Y. (2013) · Journal of Clinical Investigation · doi:10.1172/jci57175 · Cited by 183
Self-citationSuppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy
Chikuma, S., Kanamori, M., Mise‐Omata, S., & Yoshimura, A. (2017) · Cancer Science · doi:10.1111/cas.13194 · Cited by 112
Self-citationNoncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation
Cheng, H. S., Njock, M.-S., Khyzha, N., Dang, L. T., & Fish, J. E. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00422 · Cited by 69
Regulatory T Cell Stability and Plasticity in Atherosclerosis
Ali, A. J., Makings, J., & Ley, K. (2020) · Cells · doi:10.3390/cells9122665 · Cited by 65
Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis
Di Giovangiulio, M., Rizzo, A., Franzè, E., Caprioli, F., Facciotti, F., Onali, S., Favale, A., Stolfi, C., Fehling, H.-J., Monteleone, G., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02158 · Cited by 63
Wang, W.-X., Prajapati, P., Nelson, P. T., & Springer, J. E. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-01937-y · Cited by 49
Lochhead, R. B., Ma, Y., Zachary, J. F., Baltimore, D., Zhao, J. L., Weis, J. H., O'Connell, R. M., & Weis, J. J. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004212 · Cited by 42
Self-citation
Metadata
- Authors
- Lu, L.-F., Boldin, M. P., Chaudhry, A., Lin, L.-L., Taganov, K. D., Hanada, T., Yoshimura, A., Baltimore, D., & Rudensky, A. Y.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 142
- Issue
- 6
- Pages
- 914-929
- ISSN
- 0092-8674
- PMC
- PMC3049116
- Cited by
- 849
- References
- 7
- Language
- en
- Licence
- Funders
- National Institute of Biomedical Innovation
- National Institutes of Health
- Ministry of Education, Culture, Sports, Science and Technology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review